Monoclonal Antibody Facility (MAF)

Research output

Research output per year 2007 2013 2014 2015 2019 2021

• 81 Article
• 8 Review article
• 1 Editorial

Research output per year

Research output per year

Search results

• 2021

  Lysine acetylation of NKG2D ligand Rae-1 stabilizes the protein and sensitizes tumor cells to NKG2D immune surveillance

  Hu, J., Xia, X., Zhao, Q. & Li, S., Apr 1 2021, In: Cancer Letters. 502, p. 143-153 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acetylation 100%
  • Lysine 92%
  • Natural Killer Cells 88%
  • Ligands 67%
  • Proteins 34%
  8 Scopus citations
• 2020

  Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer

  Yang, W. L., Lu, Z., Guo, J., Fellman, B. M., Ning, J., Lu, K. H., Menon, U., Kobayashi, M., Hanash, S. M., Celestino, J., Skates, S. J. & Bast, R. C., Feb 15 2020, In: Cancer. 126, 4, p. 725-736 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epididymis 100%
  • Autoantibodies 77%
  • Ovarian Neoplasms 76%
  • Antigens 53%
  • Proteins 30%
  22 Scopus citations
• 2019

  A novel T-cell engaging Bi-specific antibody targeting the leukemia antigen PR1/HLA-A2

  Herrmann, A. C., Im, J. S., Pareek, S., Ruiz-Vasquez, W., Lu, S., Sergeeva, A., Mehrens, J., He, H., Alatrash, G., Sukhumalchandra, P., St John, L., Clise-Dwyer, K., Zha, D. & Molldrem, J. J., 2019, In: Frontiers in immunology. 10, JAN, 3153.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HLA-A2 Antigen 100%
  • Leukemia 60%
  • T-Lymphocytes 45%
  • Antibodies 40%
  • Acute Myeloid Leukemia 39%
  11 Scopus citations

• Anticancer immunotherapy by MFAP5 blockade inhibits fibrosis and enhances chemosensitivity in ovarian and pancreatic cancer

  Yeung, T. L., Leung, C. S., Yip, K. P., Sheng, J., Vien, L., Bover, L. C., Birrer, M. J., Wong, S. T. C. & Mok, S. C., Nov 1 2019, In: Clinical Cancer Research. 25, 21, p. 6417-6428 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreatic Neoplasms 100%
  • Ovarian Neoplasms 96%
  • Immunotherapy 92%
  • Fibrosis 78%
  • Clone Cells 55%
  35 Scopus citations

• Anti-OX40 antibody directly enhances the function of tumor-reactive CD8^þ T cells and synergizes with PI3Kb inhibition in PTEN loss melanoma

  Peng, W., Williams, L. J., Xu, C., Melendez, B., McKenzie, J. A., Chen, Y., Jackson, H. L., Voo, K. S., Mbofung, R. M., Leahey, S. E., Wang, J., Lizee, G., Tawbi, H. A., Davies, M. A., Hoos, A., Smothers, J., Srinivasan, R., Paul, E. M., Yanamandra, N. & Hwu, P., Nov 1 2019, In: Clinical Cancer Research. 25, 21, p. 6406-6416 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Anti-Idiotypic Antibodies 100%
  • Melanoma 98%
  • Psychological Inhibition 96%
  • T-Lymphocytes 73%
  • Tumor-Infiltrating Lymphocytes 66%
  37 Scopus citations

• Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo

  Aryal, N. K., Pant, V., Wasylishen, A. R., Parker-Thornburg, J., Baseler, L., El-Naggar, A. K., Liu, B., Kalia, A., Lozano, G. & Arur, S., Jan 15 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 3, p. 960-969 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphorylation 100%
  • Serine 56%
  • Caenorhabditis elegans 31%
  • HEK293 Cells 31%
  • Aspartic Acid 30%
  13 Scopus citations

• Dicer1 phosphomimetic promotes tumor progression and dissemination

  Arya, N. K., Pant, V., Wasylishen, A. R., Rimel, B. J., Baseler, L., El-Naggar, A. K., Mutch, D. G., Goodfellow, P. J., Arur, S. & Lozano, G., 2019, In: Cancer Research. 79, 10, p. 2662-2668 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplasms 100%
  • Phosphorylation 38%
  • Germ-Line Mutation 31%
  • Extracellular Signal-Regulated MAP Kinases 30%
  • Serine 27%
  9 Scopus citations

• DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

  Sutton, M. N., Lu, Z., Li, Y. C., Zhou, Y., Huang, T., Reger, A. S., Hurwitz, A. M., Palzkill, T., Logsdon, C., Liang, X., Gray, J. W., Nan, X., Hancock, J., Wahl, G. M. & Bast, R. C., Dec 10 2019, In: Cell Reports. 29, 11, p. 3448-3459.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Monomeric GTP-Binding Proteins 100%
  • Mutation 71%
  • Molecular Cluster 54%
  • Phenotype 51%
  • Growth 42%
  43 Scopus citations

• FGL2 promotes tumor progression in the CNS by suppressing CD103⁺ dendritic cell differentiation

  Yan, J., Zhao, Q., Gabrusiewicz, K., Kong, L. Y., Xia, X., Wang, J., Ott, M., Xu, J., Davis, R. E., Huo, L., Rao, G., Sun, S. C., Watowich, S. S., Heimberger, A. B. & Li, S., Dec 1 2019, In: Nature communications. 10, 1, 448.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fibrinogen 100%
  • progressions 76%
  • Fibrinogen 65%
  • tumors 65%
  • Dendritic Cells 61%
  72 Scopus citations

• Fibrinogen-like protein 2: a potential molecular target for glioblastoma treatment

  Patel, R., Traylor, J. I., Latha, K., Heimberger, A. B., Li, S. & Rao, G., Aug 3 2019, In: Expert Opinion on Therapeutic Targets. 23, 8, p. 647-649 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations

• Induction of NKG2D ligand expression on tumor cells by CD8⁺ T-cell engagement-mediated activation of nuclear factor-kappa B and p300/CBP-associated factor

  Hu, J., Xia, X., Gorlick, R. & Li, S., Dec 5 2019, In: Oncogene. 38, 49, p. 7433-7446 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • p300-CBP-associated factor 100%
  • NF-kappa B 67%
  • Ligands 44%
  • T-Lymphocytes 39%
  • Neoplasms 20%
  4 Scopus citations

• The role of fibrinogen-like protein 2 on immunosuppression and malignant progression in glioma

  Latha, K., Yan, J., Yang, Y., Gressot, L. V., Kong, L. Y., Manyam, G., Ezhilarasan, R., Wang, Q., Sulman, E. P., Davis, R. E., Huang, S., Fuller, G. N., Rao, A., Heimberger, A. B., Li, S. & Rao, G., Mar 1 2019, In: Journal of the National Cancer Institute. 111, 3, p. 292-300 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fibrinogen 100%
  • Glioma 96%
  • Immunosuppression 94%
  • Proteins 38%
  • Neoplasms 19%
  32 Scopus citations
• 2018

  E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs

  Bi, E., Li, R., Bover, L. C., Li, H., Su, P., Ma, X., Huang, C., Wang, Q., Liu, L., Yang, M., Lin, Z., Qian, J., Fu, W., Liu, Y. J. & Yi, Q., Nov 1 2018, In: Journal of Clinical Investigation. 128, 11, p. 4821-4831 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cadherins 100%
  • Multiple Myeloma 97%
  • Dendritic Cells 88%
  • Neoplasms 31%
  • Bone Marrow 20%
  27 Scopus citations

• Novel baff-receptor antibody to natively folded recombinant protein eliminates drug-resistant human b-cell malignancies in vivo

  Qin, H., Wei, G., Sakamaki, I., Dong, Z., Cheng, W. A., Lynne Smith, D., Wen, F., Sun, H., Kim, K., Cha, S., Bover, L., Neelapu, S. S. & Kwak, L. W., Mar 1 2018, In: Clinical Cancer Research. 24, 5, p. 1114-1123 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Recombinant Proteins 100%
  • Antibodies 56%
  • B-Lymphocytes 44%
  • Pharmaceutical Preparations 42%
  • Neoplasms 32%
  24 Scopus citations

• RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells

  Sutton, M. N., Yang, H., Huang, G. Y., Fu, C., Pontikos, M., Wang, Y., Mao, W., Pang, L., Yang, M., Liu, J., Parker-Thornburg, J., Lu, Z. & Bast, R. C., Apr 3 2018, In: Autophagy. 14, 4, p. 637-653 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Autophagic Cell Death 100%
  • GTP Phosphohydrolases 78%
  • Autophagy 66%
  • Ovarian Neoplasms 62%
  • Neoplasms 22%
  44 Scopus citations
• 2017

  Induction of NKG2D ligands on solid tumors requires tumor-specific CD8⁺ T cells and histone acetyltransferases

  Hu, J., Bernatchez, C., Zhang, L., Xia, X., Kleinerman, E. S., Hung, M. C., Hwu, P. & Li, S., Apr 2017, In: Cancer Immunology Research. 5, 4, p. 300-311 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Histone Acetyltransferases 100%
  • Ligands 53%
  • T-Lymphocytes 46%
  • Neoplasms 24%
  • human KAT2A protein 9%
  18 Scopus citations

• Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells

  Kerros, C., Tripathi, S. C., Zha, D., Mehrens, J. M., Sergeeva, A., Philips, A. V., Qiao, N., Peters, H. L., Katayama, H., Sukhumalchandra, P., Ruisaard, K. E., Perakis, A. A., St John, L. S., Lu, S., Mittendorf, E. A., Clise-Dwyer, K., Herrmann, A. C., Alatrash, G., Toniatti, C., Hanash, S. M., & 2 othersMa, Q. & Molldrem, J. J., Jun 16 2017, In: Journal of Biological Chemistry. 292, 24, p. 10295-10305 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuropilin-1 100%
  • Haematological 96%
  • Cross-Priming 95%
  • Leukocyte Elastase 86%
  • Antigen 56%
  30 Scopus citations

• Oncolytic adenovirus and tumor-targeting immune modulatory therapy improve autologous cancer vaccination

  Jiang, H., Rivera-Molina, Y., Gomez-Manzano, C., Clise-Dwyer, K., Bover, L., Vence, L. M., Yuan, Y., Lang, F. F., Toniatti, C., Hossain, M. B. & Fueyo, J., Jul 15 2017, In: Cancer Research. 77, 14, p. 3894-3907 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenoviridae 100%
  • Vaccination 81%
  • Neoplasms 33%
  • Oncolytic Viruses 23%
  • Therapeutics 16%
  144 Scopus citations

• PR1 peptide vaccine induces specific immunity with clinical responses in myeloid malignancies

  Qazilbash, M. H., Wieder, E., Thall, P. F., Wang, X., Rios, R., Lu, S., Kanodia, S., Ruisaard, K. E., Giralt, S. A., Estey, E. H., Cortes, J., Komanduri, K. V., Clise-Dwyer, K., Alatrash, G., Ma, Q., Champlin, R. E. & Molldrem, J. J., Mar 1 2017, In: Leukemia. 31, 3, p. 697-704 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Subunit Vaccines 100%
  • HLA-A2 Antigen 67%
  • Immunity 67%
  • MDS 11 36%
  • Cytotoxic T-Lymphocytes 35%
  81 Scopus citations

• Trastuzumab increases HER2 uptake and cross-presentation by dendritic cells

  Gall, V. A., Philips, A. V., Qiao, N., Clise-Dwyer, K., Perakis, A. A., Zhang, M., Clifton, G. T., Sukhumalchandra, P., Ma, Q., Reddy, S. M., Yu, D., Molldrem, J. J., Peoples, G. E., Alatrash, G. & Mittendorf, E. A., Oct 1 2017, In: Cancer Research. 77, 19, p. 5374-5383 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cross-Priming 100%
  • Trastuzumab 83%
  • Dendritic Cells 63%
  • Subunit Vaccines 24%
  • Tumor Necrosis Factor Receptor Superfamily, Member 7 15%
  107 Scopus citations
• 2016

  Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivo

  Sergeeva, A., He, H., Ruisaard, K., St John, L., Alatrash, G., Clise-Dwyer, K., Li, D., Patenia, R., Hong, R., Sukhumalchandra, P., You, M. J., Gagea, M., Ma, Q. & Molldrem, J. J., Jul 1 2016, In: Leukemia. 30, 7, p. 1475-1484 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HLA-A2 Antigen 100%
  • T-Cell Antigen Receptor 74%
  • Acute Myeloid Leukemia 69%
  • Antibodies 40%
  • Leukemia 10%
  26 Scopus citations

• A novel TCR-like CAR with specificity for PR1/HLA-A2 effectively targets myeloid leukemia in vitro when expressed in human adult peripheral blood and cord blood T cells

  Ma, Q., Garber, H. R., Lu, S., He, H., Tallis, E., Ding, X., Sergeeva, A., Wood, M. S., Dotti, G., Salvado, B., Ruisaard, K., Clise-Dwyer, K., John, L. S., Rezvani, K., Alatrash, G., Shpall, E. J. & Molldrem, J. J., Aug 1 2016, In: Cytotherapy. 18, 8, p. 985-994 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HLA-A2 Antigen 100%
  • Chimeric Antigen Receptors 98%
  • Myeloid Leukemia 89%
  • T-Cell Antigen Receptor 74%
  • Fetal Blood 72%
  68 Scopus citations

• Discovery of cell surface vimentin targeting mAb for direct disruption of GBM tumor initiating cells

  Noh, H., Yan, J., Hong, S., Kong, L. Y., Gabrusiewicz, K., Xia, X., Heimberger, A. B. & Li, S., 2016, In: Oncotarget. 7, 44, p. 72021-72032 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplastic Stem Cells 100%
  • Vimentin 97%
  • Glioblastoma 92%
  • Monoclonal Antibodies 11%
  • Apoptosis 9%
  40 Scopus citations

• Molecular basis of antibody binding to mucin glycopeptides in lung cancer

  Qu, J., Yu, H., Li, F., Zhang, C., Trad, A., Brooks, C., Zhang, B., Gong, T., Guo, Z., Li, Y., Ragupathi, G., Lou, Y., Hwu, P., Huang, W. & Zhou, D., Feb 2016, In: International journal of oncology. 48, 2, p. 587-594 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tandem Repeat Sequences 100%
  • Glycopeptides 99%
  • Mucins 84%
  • Lung Neoplasms 62%
  • Sugars 57%
  11 Scopus citations

• Tumor necrosis factor-α and Interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB

  Morgado, M., Sutton, M. N., Simmons, M., Warren, C. R., Lu, Z., Constantinou, P. E., Liu, J., Francis, L. L. W., Steven Conlan, R., Bast, R. C. & Carson, D. D., Mar 22 2016, In: Oncotarget. 7, 12, p. 14871-14884 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Endometrial Neoplasms 100%
  • Interferons 89%
  • Ovarian Neoplasms 88%
  • Mucins 69%
  • Tumor Necrosis Factor-alpha 69%
  40 Scopus citations
• 2015

  Angiomotin is a novel component of cadherin-11/β-catenin/p120 complex and is critical for cadherin-11-mediated cell migration

  Ortiz, A., Lee, Y. C., Yu, G., Liu, H. C., Lin, S. C., Bilen, M. A., Cho, H., Yu-Lee, L. Y. & Lin, S. H., Mar 1 2015, In: FASEB Journal. 29, 3, p. 1080-1091 12 p.

  Research output: Contribution to journal › Article › peer-review

  • osteoblast cadherin 100%
  • delta catenin 91%
  • Cell Movement 48%
  • Polarity 23%
  • Protein 12%
  29 Scopus citations

• Cell-surface Vimentin: A mislocalized protein for isolating csVimentin⁺CD133^- novel stem-like hepatocellular carcinoma cells expressing EMT markers

  Mitra, A., Satelli, A., Xia, X., Cutrera, J., Mishra, L. & Li, S., Jul 15 2015, In: International journal of cancer. 137, 2, p. 491-496 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epithelial-Mesenchymal Transition 100%
  • Vimentin 99%
  • Hepatocellular Carcinoma 77%
  • Neoplastic Stem Cells 42%
  • Proteins 35%
  71 Scopus citations

• Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

  Kochenderfer, J. N., Dudley, M. E., Kassim, S. H., Somerville, R. P. T., Carpenter, R. O., Maryalice, S. S., Yang, J. C., Phan, G. Q., Hughes, M. S., Sherry, R. M., Raffeld, M., Feldman, S., Lu, L., Li, Y. F., Ngo, L. T., Goy, A., Feldman, T., Spaner, D. E., Wang, M. L., Chen, C. C., & 6 othersKranick, S. M., Nath, A., Nathan, D. A. N., Morton, K. E., Toomey, M. A. & Rosenberg, S. A., Feb 20 2015, In: Journal of Clinical Oncology. 33, 6, p. 540-549 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • CD19 Antigens 100%
  • Chimeric Antigen Receptors 85%
  • B-Cell Lymphoma 65%
  • B-Lymphocytes 48%
  • T-Lymphocytes 39%
  1313 Scopus citations

• Circulating tumor cell enumeration with a combination of epithelial cell adhesion molecule-and cell-surface vimentin-based methods for monitoring breast cancer therapeutic response

  Satelli, A., Brownlee, Z., Mitra, A., Meng, Q. H. & Li, S., Jan 1 2015, In: Clinical chemistry. 61, 1, p. 259-266 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial Cell Adhesion Molecule 100%
  • Circulating Neoplastic Cells 89%
  • Vimentin 74%
  • Breast Neoplasms 46%
  • Marker 31%
  143 Scopus citations

• Epithelial-mesenchymal transitioned circulating tumor cells capture for detecting tumor progression

  Satelli, A., Mitra, A., Brownlee, Z., Xia, X., Bellister, S., Overman, M. J., Kopetz, S., Ellis, L. M., Meng, Q. H. & Li, S., Feb 15 2015, In: Clinical Cancer Research. 21, 4, p. 899-906 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Circulating Neoplastic Cells 100%
  • Vimentin 66%
  • Antibodies 26%
  • Neoplasms 26%
  • Single-Cell Analysis 21%
  185 Scopus citations

• New blocking antibodies against novel AGR2-C4.4A pathway reduce growth and metastasis of pancreatic tumors and increase survival in mice

  Arumugam, T., Deng, D., Bover, L., Wang, H., Logsdon, C. D. & Ramachandran, V., 2015, In: Molecular cancer therapeutics. 14, 4, p. 941-951 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Blocking Antibodies 100%
  • Adenocarcinoma 52%
  • Neoplasm Metastasis 51%
  • Growth 42%
  • Neoplasms 26%
  51 Scopus citations

• PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145

  Yang, Y., Hadjikyriacou, A., Xia, Z., Gayatri, S., Kim, D., Zurita-Lopez, C., Kelly, R., Guo, A., Li, W., Clarke, S. G. & Bedford, M. T., Mar 4 2015, In: Nature communications. 6, 6428.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatidyl-N-Methylethanolamine N-Methyltransferase 100%
  • RNA Splicing Factors 73%
  • splicing 69%
  • methylation 57%
  • Arginine 55%
  163 Scopus citations

• SNAP23 is selectively expressed in airway secretory cells and mediates baseline and stimulated mucin secretion

  Ren, B., Azzegagh, Z., Jaramillo, A. M., Zhu, Y., Pardo-Saganta, A., Bagirzadeh, R., Flores, J. R., Han, W., Tang, Y. J., Tu, J., Alanis, D. M., Evans, C. M., Guindani, M., Roche, P. A., Rajagopal, J., Chen, J., Davis, C. W., Tuvim, M. J. & Dickey, B. F., 2015, In: Bioscience reports. 35, 3, e00220.

  Research output: Contribution to journal › Article › peer-review

  • Mucins 100%
  • Trachea 38%
  • Secretagogue 29%
  • Adenosine Triphosphate 28%
  • Polystyrenes 22%
  19 Scopus citations

• T_H17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

  Meller, S., Di Domizio, J., Voo, K. S., Friedrich, H. C., Chamilos, G., Ganguly, D., Conrad, C., Gregorio, J., Le Roy, D., Roger, T., Ladbury, J. E., Homey, B., Watowich, S., Modlin, R. L., Kontoyiannis, D. P., Liu, Y. J., Arold, S. T. & Gilliet, M., Aug 19 2015, In: Nature Immunology. 16, 9, p. 970-979 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Th17 Cells 100%
  • Interleukins 92%
  • DNA 46%
  • human IL26 protein 46%
  • Interleukin Receptors 31%
  169 Scopus citations
• 2014

  A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19

  Singh, H., Huls, H., Kebriaei, P. & Cooper, L. J. N., Jan 2014, In: Immunological Reviews. 257, 1, p. 181-190 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Beauty 100%
  • Genetic Therapy 68%
  • Chimeric Antigen Receptors 49%
  • T-Lymphocytes 45%
  • Antigen-Presenting Cells 19%
  122 Scopus citations

• Arginine Methylation Facilitates the Recruitment of TOP3B to Chromatin to Prevent R Loop Accumulation

  Yang, Y., McBride, K. M., Hensley, S., Lu, Y., Chedin, F. & Bedford, M. T., Feb 6 2014, In: Molecular cell. 53, 3, p. 484-497 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Tudor Domain 100%
  • R-Loop Structures 94%
  • Arginine 54%
  • Methylation 53%
  • Chromatin 51%
  177 Scopus citations

• Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection

  Kumaresan, P. R., Manuri, P. R., Albert, N. D., Maiti, S., Singh, H., Mi, T., Roszik, J., Rabinovich, B., Olivares, S., Krishnamurthy, J., Zhang, L., Najjar, A. M., Huls, M. H., Lee, D. A., Champlin, R. E., Kontoyiannis, D. P. & Cooper, L. J. N., Jul 22 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 29, p. 10660-10665 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bioengineering 100%
  • Opportunistic Infections 83%
  • Mycoses 77%
  • Chimeric Antigen Receptors 77%
  • Carbohydrates 66%
  162 Scopus citations

• Human endogenous retrovirus type K antibodies and mRNA as serum biomarkers of early-stage breast cancer

  Wang-Johanning, F., Li, M., Esteva, F. J., Hess, K. R., Yin, B., Rycaj, K., Plummer, J. B., Garza, J. G., Ambs, S. & Johanning, G. L., Feb 1 2014, In: International Journal of Cancer. 134, 3, p. 587-595 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Biomarkers 47%
  • Breast Neoplasms 46%
  • Messenger RNA 41%
  • Antibodies 40%
  • Serum 33%
  81 Scopus citations

• IL-30 (IL27p28) attenuates liver fibrosis through inducing NKG2D-rae1 interaction between NKT and activated hepatic stellate cells in mice

  Mitra, A., Satelli, A., Yan, J., Xueqing, X., Gagea, M., Hunter, C. A., Mishra, L. & Li, S., Dec 1 2014, In: Hepatology. 60, 6, p. 2027-2039 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Hepatic Stellate Cells 100%
  • Interleukins 89%
  • Natural Killer T-Cells 77%
  • Liver Cirrhosis 75%
  • 3,5-diethoxycarbonyl-1,4-dihydrocollidine 58%
  86 Scopus citations

• Selective targeting of toll-like receptors and OX40 inhibit regulatory T-cell function in follicular lymphoma

  Voo, K. S., Foglietta, M., Percivalle, E., Chu, F., Nattamai, D., Harline, M., Lee, S. T., Bover, L., Lin, H. Y., Baladandayuthapani, V., Delgado, D., Luong, A., Davis, R. E., Kwak, L. W., Liu, Y. J. & Neelapu, S. S., Dec 15 2014, In: International journal of cancer. 135, 12, p. 2834-2846 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Follicular Lymphoma 100%
  • Toll-Like Receptors 88%
  • Regulatory T-Lymphocytes 80%
  • Remission Induction 30%
  • pidilizumab 24%
  31 Scopus citations

• Tumor lysing genetically engineered t cells loaded with multi-modal imaging agents

  Bhatnagar, P., Alauddin, M., Bankson, J. A., Kirui, D., Seifi, P., Huls, H., Lee, D. A., Babakhani, A., Ferrari, M., Li, K. C. & Cooper, L. J. N., Mar 28 2014, In: Scientific reports. 4, 4502.

  Research output: Contribution to journal › Article › peer-review

  • T-Lymphocytes 100%
  • Chimeric Antigen Receptors 87%
  • CD19-specific chimeric antigen receptor 60%
  • Neoplasms 52%
  • ferric oxide 40%
  28 Scopus citations

• Universal artificial antigen presenting cells to selectively propagate t cells expressing chimeric antigen receptor independent of specificity

  Rushworth, D., Jena, B., Olivares, S., Maiti, S., Briggs, N., Somanchi, S., Dai, J., Lee, D. & Cooper, L. J. N., May 2014, In: Journal of Immunotherapy. 37, 4, p. 204-213 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chimeric Antigen Receptors 100%
  • Antigen-Presenting Cells 77%
  • Neoplasm Antigens 35%
  • T-Lymphocytes 30%
  • T-Cell Antigen Receptor Specificity 23%
  22 Scopus citations

• Universal marker and detection tool for human sarcoma circulating tumor cells

  Satelli, A., Mitra, A., Cutrera, J. J., Devarie, M., Xia, X., Ingram, D. R., Dibra, D., Somaiah, N., Torres, K. E., Ravi, V., Ludwig, J. A., Kleinerman, E. S. & Li, S., Mar 15 2014, In: Cancer Research. 74, 6, p. 1645-1650 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Circulating Neoplastic Cells 100%
  • Sarcoma 76%
  • Vimentin 27%
  • Tumor Biomarkers 13%
  • Neoplasms 13%
  127 Scopus citations
• 2013

  Antibodies targeting human OX40 expand effector T cells and block inducible and natural regulatory T cell function

  Voo, K. S., Bover, L., Harline, M. L., Vien, L. T., Facchinetti, V., Arima, K., Kwak, L. W. & Liu, Y. J., Oct 1 2013, In: Journal of Immunology. 191, 7, p. 3641-3650 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Regulatory T-Lymphocytes 100%
  • T-Lymphocytes 62%
  • Antibodies 55%
  • Cancer Vaccines 40%
  • Interleukin-10 29%
  81 Scopus citations

• Bispecific T-cells expressing polyclonal repertoire of endogenous γδ T-cell receptors and introduced CD19-specific chimeric antigen receptor

  Deniger, D. C., Switzer, K., Mi, T., Maiti, S., Hurton, L., Singh, H., Huls, H., Olivares, S., Lee, D. A., Champlin, R. E. & Cooper, L. JN., Mar 2013, In: Molecular Therapy. 21, 3, p. 638-647 10 p.

  Research output: Contribution to journal › Article › peer-review

  • CD19-specific chimeric antigen receptor 100%
  • Chimeric Antigen Receptors 71%
  • T-Cell Antigen Receptor 54%
  • Antigen 44%
  • T-Lymphocytes 32%
  122 Scopus citations

• CARs in chronic lymphocytic leukemia - Ready to drive

  Hosing, C., Kebriaei, P., Wierda, W., Jena, B., Cooper, L. J. N. & Shpall, E., Mar 2013, In: Current hematologic malignancy reports. 8, 1, p. 60-70 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chimeric Antigen Receptors 100%
  • B-Cell Chronic Lymphocytic Leukemia 78%
  • T-Lymphocytes 45%
  • Immune Tolerance 22%
  • Adoptive Transfer 21%
  16 Scopus citations

• Caveolin-1-LRP6 signaling module stimulates aerobic glycolysis in prostate cancer

  Tahir, S. A., Yang, G., Goltsov, A., Song, K. D., Ren, C., Wang, J., Chang, W. & Thompson, T. C., Mar 15 2013, In: Cancer Research. 73, 6, p. 1900-1911 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Low Density Lipoprotein Receptor-Related Protein-6 100%
  • Caveolin 1 75%
  • Glycolysis 61%
  • Prostatic Neoplasms 46%
  • Gene Knockdown Techniques 9%
  66 Scopus citations

• Chimeric Antigen Receptor (CAR)-Specific Monoclonal Antibody to Detect CD19-Specific T Cells in Clinical Trials

  Jena, B., Maiti, S., Huls, H., Singh, H., Lee, D. A., Champlin, R. E. & Cooper, L. J. N., Mar 1 2013, In: PloS one. 8, 3, e57838.

  Research output: Contribution to journal › Article › peer-review

  • Chimeric Antigen Receptors 100%
  • clinical trials 79%
  • CD19-specific chimeric antigen receptor 69%
  • T-lymphocytes 67%
  • monoclonal antibodies 66%
  95 Scopus citations

• Clinical application of Sleeping Beauty and artificial antigen presenting cells to genetically modify T cells from peripheral and umbilical cord blood.

  Huls, M. H., Figliola, M. J., Dawson, M. J., Olivares, S., Kebriaei, P., Shpall, E. J., Champlin, R. E., Singh, H. & Cooper, L. J. N., 2013, In: Unknown Journal. 72, p. e50070

  Research output: Contribution to journal › Article › peer-review

  • Antigen-Presenting Cells 100%
  • T-cells 75%
  • Beauty 68%
  • Fetal Blood 50%
  • Blood 46%
  48 Scopus citations

• Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64

  Bhatnagar, P., Li, Z., Choi, Y., Guo, J., Li, F., Lee, D. Y., Figliola, M., Huls, H., Lee, D. A., Zal, T., Li, K. C. & Cooper, L. J. N., Jan 2013, In: Integrative Biology (United Kingdom). 5, 1, p. 231-238 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Positron 64%
  • Gold 56%
  • Positron-Emission Tomography 51%
  • Nanoparticles 49%
  • Antigen 46%
  59 Scopus citations