Clinical Pharmacokinetics and Pharmacodynamics

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Pharmacokinetics Medicine & Life Sciences
P-Glycoprotein Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
oxaliplatin Medicine & Life Sciences
Population Medicine & Life Sciences
Digoxin Medicine & Life Sciences
Kidney Medicine & Life Sciences
Genotype Medicine & Life Sciences

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Research Output 1981 2018

Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype-Guided Dosing of Tamoxifen

Nakamura, T., Toshimoto, K., Lee, W., Imamura, C. K., Tanigawara, Y. & Sugiyama, Y., Jul 1 2018, In : CPT: Pharmacometrics and Systems Pharmacology. 7, 7, p. 474-482 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Pharmacokinetics
Tamoxifen
Genotype
Predict
2 Citations

Clinical Factors Predicting Detection of T790M Mutation in Rebiopsy for EGFR-Mutant Non–small-cell Lung Cancer

Kawamura, T., Kenmotsu, H., Omori, S., Nakashima, K., Wakuda, K., Ono, A., Naito, T., Murakami, H., Omae, K., Mori, K., Tanigawara, Y., Nakajima, T., Ohde, Y., Endo, M. & Takahashi, T., Mar 1 2018, In : Clinical Lung Cancer. 19, 2, p. e219-e226

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Mutation
Recurrence

Individualized Dosing of Axitinib Based on First-Dose Area Under the Concentration–Time Curve for Metastatic Renal-Cell Carcinoma

Miura, Y., Imamura, C. K., Uchino, K., Kishida, T., Matsubara, N., Shinojima, T., Kondo, K., Hongo, F., Yoshimura, K., Tanigawara, Y. & Takano, T., Jan 1 2018, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Kidney Neoplasms
Renal Cell Carcinoma
Disease-Free Survival
Survival Rate
Hand-Foot Syndrome