Research Output 1906 2020

Filter
Letter
2019
39 Citations (Scopus)

Actively personalized vaccination trial for newly diagnosed glioblastoma

Hilf, N., Kuttruff-Coqui, S., Frenzel, K., Bukur, V., Stevanović, S., Gouttefangeas, C., Platten, M., Tabatabai, G., Dutoit, V., van der Burg, S. H., thor Straten, P., Martínez-Ricarte, F., Ponsati, B., Okada, H., Lassen, U., Admon, A., Ottensmeier, C. H., Ulges, A., Kreiter, S., von Deimling, A. & 44 others, Skardelly, M., Migliorini, D., Kroep, J. R., Idorn, M., Rodon Ahnert, J., Piró, J., Poulsen, H. S., Shraibman, B., McCann, K., Mendrzyk, R., Löwer, M., Stieglbauer, M., Britten, C. M., Capper, D., Welters, M. J. P., Sahuquillo, J., Kiesel, K., Derhovanessian, E., Rusch, E., Bunse, L., Song, C., Heesch, S., Wagner, C., Kemmer-Brück, A., Ludwig, J., Castle, J. C., Schoor, O., Tadmor, A. D., Green, E., Fritsche, J., Meyer, M., Pawlowski, N., Dorner, S., Hoffgaard, F., Rössler, B., Maurer, D., Weinschenk, T., Reinhardt, C., Huber, C., Rammensee, H. G., Singh-Jasuja, H., Sahin, U., Dietrich, P. Y. & Wick, W., Jan 10 2019, In : Nature. 565, 7738, p. 240-245 6 p.

Research output: Contribution to journalLetter

Glioblastoma
Vaccination
Vaccines
Glioma
HLA Antigens

A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia

Döhner, H., Müller-Tidow, C., Lübbert, M., Fiedler, W., Kraemer, A., Westermann, J., Bug, G., Schlenk, R. F., Krug, U., Goeldner, R. G., Hilbert, J., Taube, T. & Ottmann, O. G., May 1 2019, In : British Journal of Haematology. 185, 3, p. 583-587 5 p.

Research output: Contribution to journalLetter

Aurora Kinase B
Cytarabine
Acute Myeloid Leukemia

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia

Krombholz, C. F., Gallego-Villar, L., Sahoo, S. S., Panda, P. K., Wlodarski, M. W., Aumann, K., Hartmann, M., Lipka, D. B., Daskalakis, M., Plass, C., Niemeyer, C. M., Erlacher, M. & Flotho, C., Jul 1 2019, In : Leukemia. 33, 7, p. 1805-1810 6 p.

Research output: Contribution to journalLetter

Juvenile Myelomonocytic Leukemia
Azacitidine
Leukemia
7 Citations (Scopus)

GADD45A binds R-loops and recruits TET1 to CpG island promoters

Arab, K., Karaulanov, E., Musheev, M., Trnka, P., Schäfer, A., Grummt, I. & Niehrs, C., Feb 1 2019, In : Nature Genetics. 51, 2, p. 217-223 7 p.

Research output: Contribution to journalLetter

CpG Islands
DNA Damage
Antisense RNA
DNA
Growth
1 Citation (Scopus)

Genome-wide association study of monoclonal gammopathy of unknown significance (MGUS): comparison with multiple myeloma

Thomsen, H., Chattopadhyay, S., Weinhold, N., Vodicka, P., Vodickova, L., Hoffmann, P., Nöthen, M. M., Jöckel, K. H., Langer, C., Hajek, R., Hallmans, G., Pettersson-Kymmer, U., Ohlsson, C., Späth, F., Houlston, R., Goldschmidt, H., Hemminki, K. & Försti, A., Jul 1 2019, In : Leukemia. 33, 7, p. 1817-1821 5 p.

Research output: Contribution to journalLetter

Paraproteinemias
Genome-Wide Association Study
Multiple Myeloma

Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze

Klös, M., Thürmann, L., Bauer, M., Heinrich, J., Standl, M., von Berg, A., Schaaf, B., Weichenhan, D., Mücke, O., Plass, C., Röder, S., Herberth, G., Sack, U., Borte, M., Stangl, G. I., Eils, R., Trump, S. & Lehmann, I., Oct 1 2019, In : Allergy: European Journal of Allergy and Clinical Immunology. 74, 10, p. 2002-2006 5 p.

Research output: Contribution to journalLetter

Immunoglobulin E
Asthma
Serum

Molecular progression of SHH-activated medulloblastomas

Korshunov, A., Okonechnikov, K., Sahm, F., Ryzhova, M., Stichel, D., Sievers, P., Meyer, J., Schrimpf, D., Zheludkova, O., Golanov, A., Lichter, P., Jones, D. T. W., Pfister, S. M., von Deimling, A. & Kool, M., Aug 1 2019, In : Acta neuropathologica. 138, 2, p. 327-330 4 p.

Research output: Contribution to journalLetter

Medulloblastoma
3 Citations (Scopus)

Phase I dose-escalation trial investigating volasertib as monotherapy or in combination with cytarabine in patients with relapsed/refractory acute myeloid leukaemia

Ottmann, O. G., Müller-Tidow, C., Krämer, A., Schlenk, R. F., Lübbert, M., Bug, G., Krug, U., Bochtler, T., Voss, F., Taube, T., Liu, D., Garin-Chesa, P. & Döhner, H., Mar 2019, In : British Journal of Haematology. 184, 6, p. 1018-1021 4 p.

Research output: Contribution to journalLetter

Cytarabine
Acute Myeloid Leukemia
Pharmacokinetics
BI 6727
3 Citations (Scopus)

Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1

Lee, J. C., Villanueva-Meyer, J. E., Ferris, S. P., Sloan, E. A., Hofmann, J. W., Hattab, E. M., Williams, B. J., Guo, H., Torkildson, J., Florez, A., Van Ziffle, J., Onodera, C., Grenert, J. P., Cho, S. J., Horvai, A. E., Jones, D. T. W., Pfister, S. M., Koelsche, C., von Deimling, A., Korshunov, A. & 2 others, Perry, A. & Solomon, D. A., Mar 11 2019, In : Acta neuropathologica. 137, 3, p. 521-525 5 p.

Research output: Contribution to journalLetter

Neurofibromatosis 1
Sarcoma
Mutation

Quantitative dynamic 18F-fluorodeoxyglucose positron emission tomography/computed tomography before autologous stem cell transplantation predicts survival in multiple myeloma

Sachpekidis, C., Merz, M., Kopp-Schneider, A., Jauch, A., Raab, M. S., Sauer, S., Hillengass, J., Goldschmidt, H. & Dimitrakopoulou-Strauss, A., Aug 31 2019, In : Haematologica. 104, 9, p. E420-E423

Research output: Contribution to journalLetter

Open Access
Fluorodeoxyglucose F18
Stem Cell Transplantation
Multiple Myeloma
Positron Emission Tomography Computed Tomography
1 Citation (Scopus)

Rejection of adoptively transferred Eµ-TCL1 chronic lymphocytic leukemia cells in C57BL/6 substrains or knockout mouse lines

Öztürk, S., Roessner, P. M., Schulze-Edinghausen, L., Yazdanparast, H., Kalter, V., Lichter, P., Hanna, B. S. & Seiffert, M., Jun 1 2019, In : Leukemia. 33, 6, p. 1514-1539 26 p.

Research output: Contribution to journalLetter

B-Cell Chronic Lymphocytic Leukemia
Knockout Mice
12 Citations (Scopus)

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

NCD Risk Factor Collaboration (NCD-RisC), May 9 2019, In : Nature. 569, 7755, p. 260-264 5 p.

Research output: Contribution to journalLetter

Open Access
Body Mass Index
Obesity
Malnutrition
Urbanization
Africa South of the Sahara

Safety and efficacy of vismodegib in relapsed/refractory acute myeloid leukaemia: results of a phase Ib trial

Bixby, D., Noppeney, R., Lin, T. L., Cortes, J., Krauter, J., Yee, K., Medeiros, B. C., Krämer, A., Assouline, S., Fiedler, W., Dimier, N., Simmons, B. P., Riehl, T. & Colburn, D., May 2019, In : British Journal of Haematology. 185, 3, p. 595-598 4 p.

Research output: Contribution to journalLetter

HhAntag691
Acute Myeloid Leukemia
Safety
1 Citation (Scopus)

The GPRC5A frameshift variant c.183del is not associated with increased breast cancer risk in BRCA1 mutation carriers

Klaschik, K., Hauke, J., Neidhardt, G., Tränkle, C., Surowy, H. M., Heilmann-Heimbach, S., Rappl, G., Mangold, E., Arnold, N., Niederacher, D., Sutter, C., Burwinkel, B., Engel, C., Wappenschmidt, B., Meindl, A., Ernst, C., Weber-Lassalle, K., Weber-Lassalle, N., Schmidt, S., Borde, J. & 3 others, Schmutzler, R. K., Hahnen, E. & Pohl-Rescigno, E., Apr 1 2019, In : International Journal of Cancer. 144, 7, p. 1761-1763 3 p.

Research output: Contribution to journalLetter

Breast Neoplasms
Mutation

Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1

Thomas, C., Knerlich-Lukoschus, F., Reinhard, H., Johann, P. D., Sturm, D., Sahm, F., Bens, S., Vogt, J., Nemes, K., Oyen, F., Kordes, U., Siebert, R., Schneppenheim, R., Messing-Jünger, M., Pietsch, T., von Deimling, A., Paulus, W., Pfister, S. M., Kool, M., Frühwald, M. C. & 1 others, Hasselblatt, M., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalLetter

Neoplasms
Atypical Teratoid Tumor
Rhabdoid Tumor Predisposition Syndrome 1
Typical Teratoid Rhabdoid Tumor

Types of second primary cancers influence survival in chronic lymphocytic and hairy cell leukemia patients

Zheng, G., Chattopadhyay, S., Sud, A., Sundquist, K., Sundquist, J., Försti, A., Houlston, R. S., Hemminki, A. & Hemminki, K., Apr 1 2019, In : Blood cancer journal. 9, 4, 40.

Research output: Contribution to journalLetter

Open Access
Hairy Cell Leukemia
Second Primary Neoplasms
Survival
2018
4 Citations (Scopus)

A systematic classification of death causes in multiple myeloma

Mai, E. K., Haas, E. M., Lücke, S., Löpprich, M., Kunz, C., Pritsch, M., Knaup-Gregori, P., Raab, M-S., Schlenzka, J., Bertsch, U., Hillengass, J. & Goldschmidt, H., Mar 1 2018, In : Blood cancer journal. 8, 3, 30.

Research output: Contribution to journalLetter

Multiple Myeloma
Cause of Death
8 Citations (Scopus)

BRAF V600E status alone is not sufficient as a prognostic biomarker in pediatric low-grade glioma

Jones, D. T. W., Witt, O. & Pfister, S. M., Jan 1 2018, In : Journal of Clinical Oncology. 36, 1, 1 p.

Research output: Contribution to journalLetter

Glioma
Biomarkers
Pediatrics

Cell-free DNA in breast cancer: a long way to go

Cheng, J. & Burwinkel, B., Jul 1 2018, In : Breast Cancer Research and Treatment. 170, 1, p. 201-202 2 p.

Research output: Contribution to journalLetter

Breast Neoplasms
DNA

Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p

Sievers, P., Stichel, D., Hielscher, T., Schrimpf, D., Reinhardt, A., Wefers, A. K., Reuss, D., Jones, D. T. W., Bewerunge-Hudler, M., Hartmann, C., Baumgarten, P., Wirsching, H. G., Winther-Kristensen, B., Brokinkel, B., Ketter, R., Idoate Gastearena, M. A., Lamszus, K., Seiz-Rosenhagen, M., Mawrin, C., Harter, P. N. & 11 others, Felsberg, J., Hänggi, D., Herold-Mende, C., Berghoff, A. S., Weller, M., Pfister, S. M., Wick, W., Reifenberger, G., Preusser, M., von Deimling, A. & Sahm, F., Dec 1 2018, In : Acta neuropathologica. 136, 6, p. 975-978 4 p.

Research output: Contribution to journalLetter

Notochord
Meningioma
DNA Methylation
21 Citations (Scopus)

cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC)

Louis, D. N., Wesseling, P., Paulus, W., Giannini, C., Batchelor, T. T., Cairncross, J. G., Capper, D., Figarella-Branger, D., Lopes, M. B., Wick, W. & van den Bent, M., Mar 1 2018, In : Acta neuropathologica. 135, 3, p. 481-484 4 p.

Research output: Contribution to journalLetter

32 Citations (Scopus)

cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant

Louis, D. N., Giannini, C., Capper, D., Paulus, W., Figarella-Branger, D., Lopes, M. B., Batchelor, T. T., Cairncross, J. G., van den Bent, M., Wick, W. & Wesseling, P., Apr 1 2018, In : Acta neuropathologica. 135, 4, p. 639-642 4 p.

Research output: Contribution to journalLetter

Astrocytoma
Glioma
36 Citations (Scopus)

cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

Brat, D. J., Aldape, K., Colman, H., Holland, E. C., Louis, D. N., Jenkins, R. B., Kleinschmidt-DeMasters, B. K., Perry, A., Reifenberger, G., Stupp, R., von Deimling, A. & Weller, M., Nov 1 2018, In : Acta neuropathologica. 136, 5, p. 805-810 6 p.

Research output: Contribution to journalLetter

Astrocytoma
Glioblastoma

Cytogenetic aberrations in multiple myeloma are associated with shifts in serum immunoglobulin isotypes distribution and levels

Yadav, P., Merz, M., Mai, E. K., Försti, A., Jauch, A., Goldschmidt, H. & Hemminki, K., Mar 23 2018, In : Haematologica. 103, 4, p. e162-e164

Research output: Contribution to journalLetter

Immunoglobulin Isotypes
Multiple Myeloma
Chromosome Aberrations
Serum

Cytogenetic abnormalities in monoclonal gammopathy of undetermined significance

Merz, M., Hielscher, T., Hoffmann, K., Seckinger, A., Hose, D., Raab, M-S., Hillengass, J., Jauch, A. & Goldschmidt, H., Dec 1 2018, In : Leukemia. 32, 12, p. 2717-2719 3 p.

Research output: Contribution to journalLetter

Monoclonal Gammopathy of Undetermined Significance
Chromosome Aberrations
1 Citation (Scopus)

Familial risks of acute myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms

Sud, A., Chattopadhyay, S., Thomsen, H., Sundquist, K., Sundquist, J., Houlston, R. S. & Hemminki, K., Aug 30 2018, In : Blood. 132, 9, p. 973-976 4 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

High Accumulation of Metformin in Colonic Tissue of Subjects With Diabetes or the Metabolic Syndrome

Paleari, L., Burhenne, J., Weiss, J., Foersch, S., Roth, W., Parodi, A., Gnant, M., Bachleitner-Hofmann, T., Scherer, D., Ulrich, C. M., Stabuc, B., Puntoni, M., Coccia, G., Petrera, M., Haefeli, W. E. & DeCensi, A., Apr 2018, In : Gastroenterology. 154, 5, p. 1543-1545 3 p.

Research output: Contribution to journalLetter

Metformin
1 Citation (Scopus)

JAM-C expression as a biomarker to predict outcome of patients with acute myeloid leukemia—letter

von Bonin, M., Moll, K., Kramer, M., Oelschlägel, U., Wermke, M., Röllig, C., Thiede, C., Ehninger, G., Kraemer, A., Müller-Tidow, C., Mitroulis, I. & Bornhäuser, M., Nov 1 2018, In : Cancer Research. 78, 21, p. 6339-6341 3 p.

Research output: Contribution to journalLetter

Acute Myeloid Leukemia
Biomarkers
1 Citation (Scopus)

Multiple myeloma: family history and mortality in second primary cancers

Chattopadhyay, S., Yu, H., Sud, A., Sundquist, J., Försti, A., Hemminki, A. & Hemminki, K., Aug 1 2018, In : Blood cancer journal. 8, 8, 75.

Research output: Contribution to journalLetter

Second Primary Neoplasms
Multiple Myeloma
Mortality
6 Citations (Scopus)

Neutral tumor evolution?

The PCAWG Evolution and Heterogeneity Working Group, Dec 1 2018, In : Nature Genetics. 50, 12, p. 1630-1633 4 p.

Research output: Contribution to journalLetter

Genetic Drift
Neoplasms

Overcoming misled design and interpretation of randomised trials

Niedermaier, T., Weigl, K. & Brenner, H., Aug 1 2018, In : European journal of epidemiology. 33, 8, p. 775-776 2 p.

Research output: Contribution to journalLetter

Reply to 'Comment on 'Human papillomavirus association is the most important predictor for surgically treated patients with oropharyngeal cancer"

Wagner, S., Wittekindt, C., Sharma, S. J., Wuerdemann, N., Jüttner, T., Reuschenbach, M., Prigge, E. S., von Knebel Doeberitz, M., Gattenlöhner, S., Burkhardt, E., Pons-Kühnemann, J. & Klussmann, J. P., Feb 6 2018, In : British journal of cancer. 118, 3, p. e6

Research output: Contribution to journalLetter

Oropharyngeal Neoplasms

Response: Methods for second primary cancers evaluation have to be standardized

GEKID Cancer Survival Working Group, Mar 15 2018, In : International Journal of Cancer. 142, 6, p. 1286-1287 2 p.

Research output: Contribution to journalLetter

Second Primary Neoplasms
2 Citations (Scopus)
Fusobacterium
Early Detection of Cancer
Colorectal Neoplasms
14 Citations (Scopus)

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

Miller, C. N., Proekt, I., von Moltke, J., Wells, K. L., Rajpurkar, A. R., Wang, H., Rattay, K., Khan, I. S., Metzger, T. C., Pollack, J. L., Fries, A. C., Lwin, W. W., Wigton, E. J., Parent, A. V., Kyewski, B., Erle, D. J., Hogquist, K. A., Steinmetz, L. M., Locksley, R. M. & Anderson, M. S., Jul 26 2018, In : Nature. 559, 7715, p. 627-631 5 p.

Research output: Contribution to journalLetter

Thymocytes
Interleukin-4
Epithelial Cells
Natural Killer T-Cells
Aptitude
2 Citations (Scopus)

Updated analysis on polypharmacy and mortality from the ESTHER study

Schöttker, B., Muhlack, D. C., Hoppe, L. K., Holleczek, B. & Brenner, H., Jul 1 2018, In : European Journal of Clinical Pharmacology. 74, 7, p. 981-982 2 p.

Research output: Contribution to journalLetter

Polypharmacy
Mortality

Whole genome sequencing reveals DICER1 as a candidate predisposing gene in familial Hodgkin lymphoma

Bandapalli, O. R., Paramasivam, N., Giangiobbe, S., Kumar, A., Benisch, W., Engert, A., Witzens-Harig, M., Schlesner, M., Hemminki, K. & Försti, A., Oct 15 2018, In : International Journal of Cancer. 143, 8, p. 2076-2078 3 p.

Research output: Contribution to journalLetter

Hodgkin Disease
Genome
Genes
2017

Anästhesie zur Thrombektomie

Translated title of the contribution: Anesthesia for thrombectomySchönenberger, S., Wick, W. & Bösel, J., Sep 1 2017, In : Anaesthesist. 66, 9, p. 714-716 3 p.

Research output: Contribution to journalLetter

Thrombectomy
Anesthesia
2 Citations (Scopus)

Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach

Went, M., Sud, A., Law, P. J., Johnson, D. C., Weinhold, N., Försti, A., van Duin, M., Mitchell, J. S., Chen, B., Kuiper, R., Stephens, O. W., Bertsch, U., Campo, C., Einsele, H., Gregory, W. M., Henrion, M., Hillengass, J., Hoffmann, P., Jackson, G. H., Lenive, O. & 16 others, Nickel, J., Nöthen, M. M., da Silva Filho, M. I., Thomsen, H., Walker, B. A., Broyl, A., Davies, F. E., Langer, C., Hansson, M., Kaiser, M., Sonneveld, P., Goldschmidt, H., Hemminki, K., Nilsson, B., Morgan, G. J. & Houlston, R. S., Jun 16 2017, In : Blood cancer journal. 7, 6, p. e573

Research output: Contribution to journalLetter

Random Allocation
Multiple Myeloma
Obesity

Authors’ reply

Brenner, H. & Chen, H., Aug 28 2017, In : Clinical Epidemiology. 9, p. 437-438 2 p.

Research output: Contribution to journalLetter

10 Citations (Scopus)

DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma

Korshunov, A., Chavez, L., Northcott, P. A., Sharma, T., Ryzhova, M., Jones, D. T. W., von Deimling, A., Pfister, S. M. & Kool, M., Dec 1 2017, In : Acta neuropathologica. 134, 6, p. 965-967 3 p.

Research output: Contribution to journalLetter

Medulloblastoma
DNA Fingerprinting
DNA Methylation
10 Citations (Scopus)

Dosimetry in clinical radionuclide therapy: the devil is in the detail

Giammarile, F., Muylle, K., Delgado Bolton, R., Kunikowska, J., Haberkorn, U. & Oyen, W., Nov 1 2017, In : European Journal of Nuclear Medicine and Molecular Imaging. 44, 12

Research output: Contribution to journalLetter

Radioisotopes
Therapeutics

Evidence-based management of adult patients with diffuse glioma – Authors' reply

the European Association for Neuro-Oncology (EANO) Task Force on Gliomas, Aug 2017, In : The lancet oncology. 18, 8, p. e430-e431

Research output: Contribution to journalLetter

3 Citations (Scopus)

Genetics of gallbladder cancer

Hemminki, K., Hemminki, A., Försti, A., Sundquist, K. & Li, X., Jun 1 2017, In : The lancet oncology. 18, 6, p. e296

Research output: Contribution to journalLetter

Gallbladder Neoplasms
3 Citations (Scopus)

Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts

Meziane, I., Huhn, S., Da Silva Filho, M. I., Weinhold, N., Campo, C., Nickel, J., Hoffmann, P., Nöthen, M. M., Jöckel, K. H., Landi, S., Mitchell, J. S., Johnson, D., Jauch, A., Morgan, G. J., Houlston, R., Goldschmidt, H., Milani, P., Merlini, G., Rowcieno, D., Hawkins, P. & 6 others, Hegenbart, U., Palladini, G., Wechalekar, A., Försti, A., Schönland, S. O. & Hemminki, K., Sep 30 2017, In : Haematologica. 102, 10, p. e411-e414

Research output: Contribution to journalLetter

3 Citations (Scopus)

Go, no-go decision making for phase 3 clinical trials: ACT IV revisited – Authors' reply

Weller, M., Butowski, N., Tran, D. D., Recht, L. D., Lim, M., Hirte, H., Ashby, L., Mechtler, L., Goldlust, S. A., Iwamoto, F., Drappatz, J., O'Rourke, D. M., Wong, M., Hamilton, M. G., Finocchiaro, G., Perry, J., Wick, W., Green, J., He, Y., Turner, C. D. & 5 others, Yellin, M. J., Keler, T., Davis, T. A., Stupp, R. & Sampson, J. H., Dec 1 2017, In : The lancet oncology. 18, 12, p. e709-e710

Research output: Contribution to journalLetter

Phase III Clinical Trials
Decision Making
9 Citations (Scopus)

Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging

Zhang, Y., Hapala, J., Brenner, H. & Wagner, W., Feb 2 2017, In : Clinical epigenetics. 9, 1, 9.

Research output: Contribution to journalLetter

DNA Methylation
Life Expectancy
Biomarkers
Epigenomics
Mortality
5 Citations (Scopus)

Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature

Sahm, F., Toprak, U. H., Hübschmann, D., Kleinheinz, K., Buchhalter, I., Sill, M., Stichel, D., Schick, M., Bewerunge-Hudler, M., Schrimpf, D., Zadeh, G., Aldape, K., Herold-Mende, C., Beck, K., Staszewski, O., Prinz, M., Harosh, C. B., Eils, R., Sturm, D., Jones, D. T. W. & 6 others, Pfister, S. M., Paulus, W., Ram, Z., Schlesner, M., Grossman, R. & von Deimling, A., Jul 1 2017, In : Acta Neuropathologica. 134, 1, p. 155-158 4 p.

Research output: Contribution to journalLetter

Meningioma
Radiation
2 Citations (Scopus)

PARP inhibition in BRCA2-mutated prostate cancer

Nientiedt, C., Tolstov, Y., Volckmar, A. L., Endris, V., Bonekamp, D., Haberkorn, U., Jäger, D., Sültmann, H., Stenzinger, A., Hohenfellner, M., Grüllich, C. & Duensing, S., Jan 1 2017, In : Annals of Oncology. 28, 1, p. 189-191 3 p.

Research output: Contribution to journalLetter

Prostatic Neoplasms
2 Citations (Scopus)

Reply to Richarme: Evidence against a role of DJ-1 in methylglyoxal detoxification

Pfaff, D. H., Fleming, T., Nawroth, P. & Telemann, A., Jan 1 2017, In : Journal of Biological Chemistry. 292, 31, p. 12784-12785 2 p.

Research output: Contribution to journalLetter

Pyruvaldehyde
Oncogene Proteins