Functional and Structural Genomics

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Genes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Neuroblastoma Medicine & Life Sciences
Proteins Medicine & Life Sciences
Chromosomes Medicine & Life Sciences
DNA Medicine & Life Sciences
Genome Medicine & Life Sciences
RNA Interference Medicine & Life Sciences

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Research Output 1975 2018

A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment

Shen, J., Najafi, S., Stäble, S., Fabian, J., Koeneke, E., Kolbinger, F. R., Wrobel, J. K., Meder, B., Distel, M., Heimburg, T., Sippl, W., Jung, M., Peterziel, H., Kranz, D., Boutros, M., Westermann, F., Witt, O. & Oehme, I., Mar 7 2018, (Accepted/In press) In : Cell death and differentiation. p. 1-18 18 p.

Research output: Contribution to journalArticle

RNA Interference
Neuroblastoma
Cell Line
Therapeutics
Local Area Networks

Altered nuclear envelope structure and proteasome function of micronuclei

Maass, K. K., Rosing, F., Ronchi, P., Willmund, K. V., Devens, F., Hergt, M., Herrmann, H., Lichter, P. & Ernst, A., Oct 15 2018, In : Experimental Cell Research. 371, 2, p. 353-363 11 p.

Research output: Contribution to journalArticle

Nuclear Envelope
Proteasome Endopeptidase Complex
Nuclear Proteins
Lysosomes
DNA Damage
3 Citations

Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice

Leibing, T., Géraud, C., Augustin, I., Boutros, M., Augustin, H. G., Okun, J. G., Langhans, C. D., Zierow, J., Wohlfeil, S. A., Olsavszky, V., Schledzewski, K., Goerdt, S. & Koch, P. S., Aug 1 2018, In : Hepatology. 68, 2, p. 707-722 16 p.

Research output: Contribution to journalArticle

Liver
Growth
Hepatocytes
Endothelial Cells
Sialomucins