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Dive into the research topics where Institute for Applied Cancer Science (IACS) is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
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NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
Jeong, J., Hausmann, S., Dong, H., Szczepski, K., Flores, N. M., Garcia Gonzalez, A., Shi, L., Lu, X., Lempiäinen, J., Jakab, M., Zeng, L., Chasan, T., Bareke, E., Dong, R., Carlson, E., Padilla, R., Husmann, D., Thompson, J., Shipman, G. A. & Zahn, E. & 21 others, , Jan 1 2026, In: Nature. 649, 8095, p. 205-215 11 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
Structure-Guided Development of NRAS G12D Inhibitors Based on a 5-Azaindole Core
Cox, J. B., Nair, V., Mandal, P., Reyna, N., Tran, T., Mustachio, L. M., Bardenhagen, J., Fawver, J., Shepard, H., Hickey, A. M., Wu, Q., Rodriguez, C., Yu, F., Phan, P., Mendiola, A. J., Johnson, R., Thapar, R., Johnson, T., Jiang, Y. & Cross, J. B. & 6 others, , Feb 12 2026, In: ACS Medicinal Chemistry Letters. 17, 2, p. 425-432 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A Hit Prioritization Strategy for Compound Library Screening Using LiP-MS and Molecular Dynamics Simulations Applied to KRas G12D Inhibitors
Absar, F., Novy, B., Nagy, E., Petrotchenko, E. V., Popov, K. I., Cross, J. B., Thapar, R. & Borchers, C. H., Sep 23 2025, In: Analytical Chemistry. 97, 37, p. 20228-20236 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations