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Fas Ligand Protein Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Granulocyte Colony-Stimulating Factor Medicine & Life Sciences
CD95 Antigens Medicine & Life Sciences
Genes Medicine & Life Sciences
Phosphatidylserines Medicine & Life Sciences
Granulocyte Colony-Stimulating Factor Receptors Medicine & Life Sciences
Macrophages Medicine & Life Sciences

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Profiles

No photo of Shigekazu Nagata
19742019

Research Output 1974 2019

MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation

Nishi, C., Yanagihashi, Y., Segawa, K. & Nagata, S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 18, p. 7221-7230 10 p.

Research output: Contribution to journalArticle

Signal transduction
Cell proliferation
Receptor Protein-Tyrosine Kinases
Signal Transduction
Cells

Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure

Sakuragi, T., Kosako, H. & Nagata, S., Feb 19 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 2907-2912 6 p.

Research output: Contribution to journalArticle

Phosphatidylserines
Phosphorylation
Phosphoric Monoester Hydrolases
Phosphotransferases
Down-Regulation

Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution

Tsuji, T., Cheng, J., Tatematsu, T., Ebata, A., Kamikawa, H., Fujita, A., Gyobu, S., Segawa, K., Arai, H., Taguchi, T., Nagata, S. & Fujimoto, T., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13368-13373 6 p.

Research output: Contribution to journalArticle

Open Access
Phosphatidylserines
Endoplasmic Reticulum
Nuclear Envelope
Phospholipids
Fibroblasts