Abdullah A Osman

Assistant Professor

  • 1501 Citations
  • 13 h-Index
20002019
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Fingerprint Dive into the research topics where Abdullah A Osman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Head and Neck Neoplasms Medicine & Life Sciences
Mutation Medicine & Life Sciences
Cisplatin Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
AMP-Activated Protein Kinases Medicine & Life Sciences
Inner Auditory Hair Cells Medicine & Life Sciences
Insulin Medicine & Life Sciences
Apoptosis Medicine & Life Sciences

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Research Output 2000 2019

  • 1501 Citations
  • 13 h-Index
  • 19 Article
  • 1 Review article

COTI-2, a novel thiosemicarbazone derivative, exhibits antitumor activity in HNSCC through p53-dependent and -independent mechanisms

Lindemann, A., Patel, A. A., Silver, N. L., Tang, L., Liu, Z., Wang, L., Tanaka, N., Rao, X., Takahashi, H., Maduka, N. K., Zhao, M., Chen, T. C., Liu, W. W., Gao, M., Wang, J., Frank, S. J., Hittelman, W. N., Mills, G. B., Myers, J. N. & Osman, A. A., Sep 15 2019, In : Clinical Cancer Research. 25, 18, p. 5650-5662 13 p.

Research output: Contribution to journalArticle

Open Access
Thiosemicarbazones
Radiation
Cisplatin
Apoptosis
RNA Sequence Analysis
5 Citations (Scopus)

Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1

Tanaka, N., Zhao, M., Tang, L., Patel, A. A., Xi, Q., Van Hieu, T., Takahashi, H., Osman, A. A., Zhang, J., Wang, J., Myers, J. N. & Zhou, G., Mar 1 2018, In : Oncogene. 37, 10, p. 1279-1292 14 p.

Research output: Contribution to journalArticle

Transcription Factors
AMP-Activated Protein Kinases
Forkhead Transcription Factors
Down-Regulation
Neoplasm Metastasis
8 Citations (Scopus)

Head and neck cancer organoids established by modification of the CTOS method can be used to predict in vivo drug sensitivity

Tanaka, N., Osman, A. A., Takahashi, Y., Lindemann, A., Patel, A. A., Zhao, M., Takahashi, H. & Myers, J. N., Dec 1 2018, In : Oral Oncology. 87, p. 49-57 9 p.

Research output: Contribution to journalArticle

Organoids
Head and Neck Neoplasms
Pharmaceutical Preparations
Neoplasms
docetaxel
7 Citations (Scopus)

Targeting the DNA Damage Response in OSCC with TP53 Mutations

Lindemann, A., Takahashi, H., Patel, A. A., Osman, A. A. & Myers, J. N., Jun 1 2018, In : Journal of Dental Research. 97, 6, p. 635-644 10 p.

Research output: Contribution to journalReview article

DNA Damage
Squamous Cell Carcinoma
Mutation
Drug Therapy
DNA Repair
8 Citations (Scopus)

Replication stress leading to apoptosis within the S-phase contributes to synergism between vorinostat and AZD1775 in HNSCC harboring high-risk TP53 mutation

Tanaka, N., Patel, A. A., Tang, L., Silver, N. L., Lindemann, A., Takahashi, H., Jaksik, R., Rao, X., Kalu, N. N., Chen, T. C., Wang, J., Frederick, M. J., Johnson, F. M., Netto, F. O. G., Fu, S., Kimmel, M., Wang, J., Hittelman, W. N., Pickering, C. R., Myers, J. N. & 1 others, Osman, A. A., Nov 1 2017, In : Clinical Cancer Research. 23, 21, p. 6541-6554 14 p.

Research output: Contribution to journalArticle

S Phase
Apoptosis
Mutation
Mouth Neoplasms
Homologous Recombination