If you made any changes in Pure, your changes will be visible here soon.

Research Output 1994 2019

Filter
Article
2019

Activating p53 family member TAp63: A novel therapeutic strategy for targeting p53-altered tumors

Gunaratne, P. H., Pan, Y., Rao, A. K., Lin, C., Hernandez-Herrera, A., Liang, K., Rait, A. S., Venkatanarayan, A., Benham, A. L., Rubab, F., Kim, S. S., Rajapakshe, K., Chan, C. K., Mangala, L. S., Lopez, G., Sood, A. K., Rowat, A. C., Coarfa, C., Pirollo, K. F., Flores, E. R. & 1 others, Chang, E. H., Jul 15 2019, In : Cancer. 125, 14, p. 2409-2422 14 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Neoplasms
B-Cell Lymphoma
Therapeutics
Heterografts
1 Citation (Scopus)

EGFL6 promotes breast cancer by simultaneously enhancing cancer cell metastasis and stimulating tumor angiogenesis

An, J., Du, Y., Fan, X., Wang, Y., Ivan, C., Zhang, X. G., Sood, A. K., An, Z. & Zhang, N., Mar 21 2019, In : Oncogene. 38, 12, p. 2123-2134 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasm Metastasis
Neoplasms
Cell Movement
Heterografts
6 Citations (Scopus)

exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids

Murillo, O. D., Thistlethwaite, W., Rozowsky, J., Subramanian, S. L., Lucero, R., Shah, N., Jackson, A. R., Srinivasan, S., Chung, A., Laurent, C. D., Kitchen, R. R., Galeev, T., Warrell, J., Diao, J. A., Welsh, J. A., Hanspers, K., Riutta, A., Burgstaller-Muehlbacher, S., Shah, R. V., Yeri, A. & 38 others, Jenkins, L. M., Ahsen, M. E., Cordon-Cardo, C., Dogra, N., Gifford, S. M., Smith, J. T., Stolovitzky, G., Tewari, A. K., Wunsch, B. H., Yadav, K. K., Danielson, K. M., Filant, J., Moeller, C., Nejad, P., Paul, A., Simonson, B., Wong, D. K., Zhang, X., Balaj, L., Gandhi, R., Sood, A. K., Alexander, R. P., Wang, L., Wu, C., Wong, D. T. W., Galas, D. J., Van Keuren-Jensen, K., Patel, T., Jones, J. C., Das, S., Cheung, K. H., Pico, A. R., Su, A. I., Raffai, R. L., Laurent, L. C., Roth, M. E., Gerstein, M. B. & Milosavljevic, A., Apr 4 2019, In : Cell. 177, 2, p. 463-477.e15

Research output: Contribution to journalArticle

Atlases
RNA
Deconvolution
Saliva
Urine

GnRH-R-Targeted Lytic Peptide Sensitizes BRCA Wild-type Ovarian Cancer to PARP Inhibition

Ma, S., Pradeep, S., Villar-Prados, A., Wen, Y., Bayraktar, E., Mangala, L. S., Kim, M. S., Wu, S., Hu, W., Rodriguez-Aguayo, C., Leuschner, C., Liang, X., Ram, P., Schlacher, K., Coleman, R. & Sood, A. K., May 1 2019, In : Molecular cancer therapeutics. 18, 5, p. 969-979 11 p.

Research output: Contribution to journalArticle

Gonadotropin-Releasing Hormone
Ovarian Neoplasms
Peptides
Protein Array Analysis
Comet Assay

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

Chen, X., Mangala, L. S., Mooberry, L., Bayraktar, E., Dasari, S. K., Ma, S., Ivan, C., Court, K. A., Rodriguez-Aguayo, C., Bayraktar, R., Raut, S., Sabnis, N., Kong, X., Yang, X., Lopez, G., Lacko, A. G. & Sood, A. K., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

MicroRNAs
Ovarian Neoplasms
Neoplasms
CD36 Antigens
Vascular Endothelial Growth Factor A

Mucinous borderline ovarian tumor versus invasive well-differentiated mucinous ovarian cancer: Difference in characteristics and outcomes

Matsuo, K., Machida, H., Mandelbaum, R. S., Grubbs, B. H., Roman, L. D., Sood, A. K. & Gershenson, D. M., May 1 2019, In : Gynecologic oncology. 153, 2, p. 230-237 8 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Propensity Score
Survival
SEER Program
3 Citations (Scopus)

Ovarian cancer cell-derived lysophosphatidic acid induces glycolytic shift and cancer-associated fibroblast-phenotype in normal and peritumoral fibroblasts

Radhakrishnan, R., Ha, J. H., Jayaraman, M., Liu, J., Moxley, K. M., Isidoro, C., Sood, A. K., Song, Y. S. & Dhanasekaran, D. N., Feb 1 2019, In : Cancer Letters. 442, p. 464-474 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Fibroblasts
Phenotype
Glycolysis
Conditioned Culture Medium

Oxytocin in the tumor microenvironment is associated with lower inflammation and longer survival in advanced epithelial ovarian cancer patients

Cuneo, M. G., Szeto, A., Schrepf, A., Kinner, E. M., Schachner, B. I., Ahmed, R., Thaker, P. H., Goodheart, M., Bender, D., Cole, S. W., McCabe, P. M., Sood, A. K., Lutgendorf, S. K. & Mendez, A. J., Aug 1 2019, In : Psychoneuroendocrinology. 106, p. 244-251 8 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Oxytocin
Inflammation
Survival
Interleukin-6

Pan-cancer genomic analysis links 3’UTR DNA methylation with increased gene expression in T cells

McGuire, M. H., Herbrich, S. M., Dasari, S. K., Wu, S., Wang, Y., Rupaimoole, R., Lopez, G., Baggerly, K. A. & Sood, A. K., May 1 2019, In : EBioMedicine. 43, p. 127-137 11 p.

Research output: Contribution to journalArticle

Open Access
T-cells
DNA Methylation
Gene expression
T-Lymphocytes
Gene Expression
1 Citation (Scopus)

Performance of the MasSpec pen for rapid diagnosis of Ovarian cancer

Sans, M., Zhang, J., Lin, J. Q., Feider, C. L., Giese, N., Breen, M. T., Sebastian, K., Liu, J., Sood, A. K. & Eberlin, L. S., May 1 2019, In : Clinical chemistry. 65, 5, p. 674-683 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Tissue
Peritoneum
Mass spectrometers
Learning systems
3 Citations (Scopus)

Perineural invasion (PNI) in vulvar carcinoma: A review of 421 cases

Salcedo, M. P., Sood, A. K., dos Reis, R., Ramalingam, P., Chen, C., Frumovitz, M., Jhingran, A., Pitcher, B., Ramirez, P. T. & Schmeler, K. M., Jan 1 2019, In : Gynecologic oncology. 152, 1, p. 101-105 5 p.

Research output: Contribution to journalArticle

Carcinoma
Disease-Free Survival
Lichen Sclerosus et Atrophicus
Survival
Medical Records

Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein Brd4

Villar-Prados, A., Wu, S., Court, K. A., Ma, S., LaFargue, C., Chowdhury, M. A., Engelhardt, M. I., Ivan, C., Ram, P., Wang, Y., Baggerly, K. A., Rodriguez-Aguayo, C., Lopez, G., Yang, S. M., Maloney, D. J., Yoshioka, M., Strovel, J. W., Roszik, J. & Sood, A. K., Feb 1 2019, In : Molecular cancer therapeutics. 18, 2, p. 421-436 16 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Small Interfering RNA
Therapeutics
Down-Regulation
Neoplasms
3 Citations (Scopus)

PRKRA/PACT expression promotes chemoresistance of mucinous ovarian cancer

Hisamatsu, T., McGuire, M., Wu, S., Rupaimoole, R., Pradeep, S., Bayraktar, E., Noh, K., Hu, W., Hansen, J. M., Lyons, Y. A., Gharpure, K. M., Nagaraja, A. S., Mangala, L. S., Mitamura, T., Rodriguez-Aguayo, C., Eun, Y. G., Rose, J., Bartholomeusz, G., Ivan, C., Lee, J-S. & 5 others, Matsuo, K., Frumovitz, M., Wong, K. K., Lopez, G. & Sood, A. K., Jan 1 2019, In : Molecular cancer therapeutics. 18, 1, p. 162-172 11 p.

Research output: Contribution to journalArticle

oxaliplatin
Ovarian Neoplasms
Small Interfering RNA
Platinum
Phosphotransferases

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis

Rodriguez-Aguayo, C., Bayraktar, E., Ivan, C., Aslan, B., Mai, J., He, G., Mangala, L. S., Jiang, D., Nagaraja, A. S., Ozpolat, B., Chavez-Reyes, A., Ferrari, M., Mitra, R., Siddik, Z. H., Shen, H., Yang, X., Sood, A. K. & Lopez, G., Feb 1 2019, In : EBioMedicine. 40, p. 290-304 15 p.

Research output: Contribution to journalArticle

Dinoprostone
Cisplatin
Ovary
Carcinogenesis
Up-Regulation

Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis

Azam, S. H., Porrello, A., Harrison, E. B., Leslie, P. L., Liu, X., Waugh, T. A., Belanger, A., Mangala, L. S., Lopez, G., Wilson, H. L., McCann, J. V., Kim, W. Y., Sood, A. K., Liu, J., Dudley, A. C. & Pecot, C. V., Jun 27 2019, In : Oncogene. 38, 26, p. 5191-5210 20 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Cell Cycle
Endothelial Cells
MicroRNAs
Neoplasm Metastasis
6 Citations (Scopus)

Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation

Srinivasan, S., Yeri, A., Cheah, P. S., Chung, A., Danielson, K., De Hoff, P., Filant, J., Laurent, C. D., Laurent, L. D., Magee, R., Moeller, C., Murthy, V. L., Nejad, P., Paul, A., Rigoutsos, I., Rodosthenous, R., Shah, R. V., Simonson, B., To, C., Wong, D. & 14 others, Yan, I. K., Zhang, X., Balaj, L., Breakefield, X. O., Daaboul, G., Gandhi, R., Lapidus, J., Londin, E., Patel, T., Raffai, R. L., Sood, A. K., Alexander, R. P., Das, S. & Laurent, L. C., Apr 4 2019, In : Cell. 177, 2, p. 446-462.e16

Research output: Contribution to journalArticle

RNA Sequence Analysis
RNA
MicroRNAs
Research Personnel
Ribonucleoproteins
2018
5 Citations (Scopus)

Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling

González-González, A., Muñoz-Muela, E., Marchal, J. A., Cara, F. E., Molina, M. P., Cruz-Lozano, M., Jiménez, G., Verma, A., Ramírez, A., Qian, W., Chen, W., Kozielski, A. J., Elemento, O., Martín-Salvago, M. D., Luque, R. J., Rosa-Garrido, C., Landeira, D., Quintana-Romero, M., Rosato, R. R., García, M. A. & 9 others, Ramirez-Tortosa, C. L., Kim, H., Rodriguez-Aguayo, C., Lopez, G., Sood, A. K., Lorente, J. A., Sánchez-Rovira, P., Chang, J. C. & Granados-Principal, S., Nov 15 2018, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 24, 22, p. 5697-5709 13 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 4
Triple Negative Breast Neoplasms
Survival
Breast Neoplasms
Heterografts
2 Citations (Scopus)

ADH1B promotes mesothelial clearance and ovarian cancer infiltration

Gharpure, K. M., Lara, O. D., Wen, Y., Pradeep, S., LaFargue, C., Ivan, C., Rupaimoole, R., Hu, W., Mangala, L. S., Wu, S., Nagaraja, A. S., Baggerly, K. A. & Sood, A. K., May 18 2018, In : Oncotarget. 9, 38, p. 25115-25126 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Adjuvant Chemotherapy
Cell Adhesion
Extracellular Matrix

Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens

Nagaraja, A. S., Dood, R. L., Armaiz-Pena, G., Kang, Y., Wu, S., Allen, J. K., Jennings, N. B., Mangala, L. S., Pradeep, S., Lyons, Y. A., Haemmerle, M., Gharpure, K. M., Sadaoui, N. C., Rodriguez-Aguayo, C., Ivan, C., Wang, Y., Baggerly, K. A., Ram, P., Lopez, G., Liu, J. & 5 others, Mok, S., Cohen, L., Lutgendorf, S. K., Cole, S. W. & Sood, A. K., Jun 7 2018, In : JCI insight. 3, 11

Research output: Contribution to journalArticle

Open Access
64 Citations (Scopus)

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journalArticle

Atlases
Genes
Genome
Survival
Neoplasms
21 Citations (Scopus)

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 386-399.e12

Research output: Contribution to journalArticle

Genes
Tumors
Neoplasms
Computational methods
Chromatin
4 Citations (Scopus)

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

The Cancer Genome Atlas Research Network, Oct 24 2018, In : Cell Systems. 7, 4, p. 422-437.e7

Research output: Contribution to journalArticle

Transforming Growth Factors
Neoplasms
Sequence Deletion
Genes
Gastrointestinal Neoplasms
1 Citation (Scopus)

Association of biobehavioral factors with non-coding RNAs in cervical cancer

Liu, Q., Lu, C., Dai, W., Li, K., Xu, J., Huang, Y., Li, G., Kang, Y., Sood, A. K. & Xu, C., Jan 1 2018, In : BioScience Trends. 12, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Untranslated RNA
Uterine Cervical Neoplasms
cancer
Gene Ontology
10 Citations (Scopus)

A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression

Velazquez-Torres, G., Shoshan, E., Ivan, C., Huang, L., Fuentes-Mattei, E., Paret, H., Kim, S. J., Rodriguez-Aguayo, C., Xie, V., Brooks, D., Jones, S. J. M., Robertson, A. G., Calin, G. A., Lopez-Berenstein, G., Sood, A. K. & Bar Eli, M., Dec 1 2018, In : Nature communications. 9, 1, 461.

Research output: Contribution to journalArticle

editing
MicroRNAs
progressions
Melanoma
3' Untranslated Regions
1 Citation (Scopus)

ATP11B mediates platinum resistance in ovarian cancer

Moreno-Smith, M., Halder, J. B., Meltzer, P. S., Gonda, T. A., Mangala, L. S., Rupaimoole, R., Lu, C., Nagaraja, A. S., Gharpure, K. M., Kang, Y., Rodriguez-Aguayo, C., Vivas-Mejia, P. E., Zand, B., Schmandt, R., Wang, H., Langley, R. R., Jennings, N. B., Ivan, C., Coffin, J. E., Armaiz, G. N. & 10 others, Bottsford-Miller, J., Kim, S. B., Halleck, M. S., Hendrix, M. J., Bornman, W., Bar Eli, M., Lee, J-S., Siddik, Z. H., Lopez-Berestein, G. & Sood, A. K., Jul 2 2018, In : The Journal of clinical investigation. 128, 7, 1 p.

Research output: Contribution to journalArticle

Open Access
Platinum
Ovarian Neoplasms

Bioactive lipid metabolism in platelet “first responder” and cancer biology

Kanikarla Marie, P., Kopetz, E. S., Hawk, E., Millward, S., Sood, A. K., Gresele, P., Overman, M. J., Honn, K. & Menter, D. G., Sep 1 2018, In : Cancer and Metastasis Reviews. 37, 2-3, p. 439-454 16 p.

Research output: Contribution to journalArticle

Lipid Metabolism
Blood Platelets
Eicosanoids
Thromboxanes
Epoprostenol
10 Citations (Scopus)

Biobehavioral modulation of the exosome transcriptome in ovarian carcinoma

Lutgendorf, S. K., Thaker, P. H., Arevalo, J. M., Goodheart, M. J., Slavich, G. M., Sood, A. K. & Cole, S. W., Feb 1 2018, In : Cancer. 124, 3, p. 580-586 7 p.

Research output: Contribution to journalArticle

Exosomes
Transcriptome
Social Support
Activating Transcription Factors
Carcinoma
5 Citations (Scopus)

Bone protection by inhibition of microRNA-182

Inoue, K., Deng, Z., Chen, Y., Giannopoulou, E., Xu, R., Gong, S., Greenblatt, M. B., Mangala, L. S., Lopez, G., Kirsch, D. G., Sood, A. K., Zhao, L. & Zhao, B., Dec 1 2018, In : Nature communications. 9, 1, 4108.

Research output: Contribution to journalArticle

arthritis
interferon
MicroRNAs
Osteogenesis
Interferons
18 Citations (Scopus)

Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance

Leung, S. L. C., Yeung, T-L., Yip, K. P., Wong, K. K., Ho, S. Y., Mangala, L. S., Sood, A. K., Lopez, G., Sheng, J., Wong, S. T. C., Birrer, M. J. & Mok, S., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 589-606 18 p.

Research output: Contribution to journalArticle

Lipoma
Ovarian Neoplasms
Proteins
Endothelial Cells
Small Interfering RNA
6 Citations (Scopus)

CD44-targeting PLGA nanoparticles incorporating paclitaxel and FAK siRNA overcome chemoresistance in epithelial ovarian cancer

Byeon, Y., Lee, J. W., Choi, W. S., Won, J. E., Kim, G. H., Kim, M. G., Wi, T. I., Lee, J. M., Kang, T. H., Jung, I. D., Cho, Y. J., Ahn, H. J., Shin, B. C., Lee, Y. J., Sood, A. K., Han, H. D. & Park, Y. M., Nov 1 2018, In : Cancer Research. 78, 21, p. 6247-6256 10 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Paclitaxel
Nanoparticles
Small Interfering RNA
Ovarian Neoplasms
91 Citations (Scopus)

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

The Cancer Genome Atlas Network, Apr 5 2018, In : Cell. 173, 2, p. 291-304.e6

Research output: Contribution to journalArticle

Tumors
Tissue
Histology
Methylation
Oncology
31 Citations (Scopus)

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 721-735.e8

Research output: Contribution to journalArticle

Adenocarcinoma
Neoplasms
Genome
Chromosomal Instability
Rectum
24 Citations (Scopus)

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

The Cancer Genome Atlas Research Network, Aug 13 2018, In : Cancer Cell. 34, 2, p. 211-224.e6

Research output: Contribution to journalArticle

Alternative Splicing
Neoplasms
Exons
Exome
Peptides
110 Citations (Scopus)

Comprehensive Characterization of Cancer Driver Genes and Mutations

The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 371-385.e18

Research output: Contribution to journalArticle

Neoplasm Genes
Tumors
Genes
Mutation
Neoplasms
5 Citations (Scopus)

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

The Cancer Genome Atlas Research Network, Oct 30 2018, In : Cell Reports. 25, 5, p. 1304-1317.e5

Research output: Contribution to journalArticle

Genes
Neoplasms
Squamous Cell Neoplasms
Tumors
Atlases
Ovarian Neoplasms
Neoplasms
Laparoscopy
Stomach Diseases
Diaphragm
3 Citations (Scopus)

Defining survivorship trajectories across patients with solid tumors: An evidence-based approach

Dood, R. L., Zhao, Y., Armbruster, S. D., Coleman, R., Tworoger, S., Sood, A. K. & Baggerly, K. A., Jan 1 2018, In : JAMA Oncology. 4, 11, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

Survival Rate
Neoplasms
Mortality
Population
Primary Care Physicians
29 Citations (Scopus)

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 227-238.e3

Research output: Contribution to journalArticle

Human Development
Phosphotransferases
Genes
Gene expression
Tumors
3 Citations (Scopus)

Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer

Kanlikilicer, P., Bayraktar, R., Denizli, M., Rashed, M. H., Ivan, C., Aslan, B., Mitra, R., Karagoz, K., Bayraktar, E., Zhang, X., Rodriguez-Aguayo, C., El-Arabey, A. A., Kahraman, N., Baydogan, S., Ozkayar, O., Gatza, M. L., Ozpolat, B., Calin, G. A., Sood, A. K. & Lopez, G., Dec 1 2018, In : EBioMedicine. 38, p. 100-112 13 p.

Research output: Contribution to journalArticle

Macrophages
MicroRNAs
Ovarian Neoplasms
Paclitaxel
Tumors
8 Citations (Scopus)

FABP4 as a key determinant of metastatic potential of ovarian cancer

Gharpure, K. M., Pradeep, S., Sans, M., Rupaimoole, R., Ivan, C., Wu, S., Bayraktar, E., Nagaraja, A. S., Mangala, L. S., Zhang, X., Haemmerle, M., Hu, W., Rodriguez-Aguayo, C., McGuire, M., Mak, S. L. CELIA., Chen, X., Tran, M. A., Villar-Prados, A., Pena, G. A., Kondetimmanahalli, R. & 8 others, Nini, R., Koppula, P., Ram, P., Liu, J., Lopez, G., Baggerly, K. A., S. Eberlin, L. & Sood, A. K., Dec 1 2018, In : Nature communications. 9, 1, 2923.

Research output: Contribution to journalArticle

determinants
Ovarian Neoplasms
cancer
Cells
Surgery
22 Citations (Scopus)

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 194-212.e6

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
MicroRNAs
Mutation
Epithelial Cells
Squamous Cell Neoplasms
38 Citations (Scopus)

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 676-689.e3

Research output: Contribution to journalArticle

Aneuploidy
Chromosomes
Neoplasms
Genome
Mutation Rate
56 Citations (Scopus)

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 239-254.e6

Research output: Contribution to journalArticle

DNA Repair-Deficiency Disorders
Atlases
DNA Damage
Repair
Genes
9 Citations (Scopus)

HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway

Liu, Y., Choi, D. S., Sheng, J., Ensor, J. E., Liang, D. H., Rodriguez-Aguayo, C., Polley, A., Benz, S., Elemento, O., Verma, A., Cong, Y., Wong, H., Qian, W., Li, Z., Granados-Principal, S., Lopez, G., Landis, M. D., Rosato, R. R., Dave, B., Wong, S. & 3 others, Marchetti, D., Sood, A. K. & Chang, J. C., Jan 1 2018, In : Stem Cell Reports. 10, 1, p. 212-227 16 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Neoplastic Stem Cells
Stem cells
Breast Neoplasms
Transcription
3 Citations (Scopus)

Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma

Matsuo, K., Wong, K. K., Fotopoulou, C., Blake, E. A., Robertson, S. E., Pejovic, T., Frimer, M., Pardeshi, V., Hu, W., Choi, J. S., Sun, C. C., Richmond, A. M., Marcus, J. Z., Hilliard, M. A. M., Mostofizadeh, S., Mhawech-Fauceglia, P., Abdulfatah, E., Post, M. D., Saglam, O., Shahzad, M. M. K. & 6 others, Karabakhtsian, R. G., Ali-Fehmi, R., Gabra, H., Roman, L. D., Sood, A. K. & Gershenson, D. M., Feb 1 2018, In : Journal of Surgical Oncology. 117, 2, p. 236-244 9 p.

Research output: Contribution to journalArticle

Blood Vessels
Carcinoma
Survival
Neoplasms
Odds Ratio

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

Mangala, L. S., Wang, H., Jiang, D., Wu, S., Somasunderam, A., Volk, D. E., Lokesh, G. L. R., Li, X., Pradeep, S., Yang, X., Haemmerle, M., Rodriguez-Aguayo, C., Nagaraja, A. S., Rupaimoole, R., Bayraktar, E., Bayraktar, R., Li, L., Tanaka, T., Hu, W., Ivan, C. & 13 others, Gharpure, K. M., McGuire, M. H., Thiviyanathan, V., Zhang, X., Maiti, S. N., Bulayeva, N., Choi, H. J., Dorniak, P. L., Cooper, L. J., Rosenblatt, K. P., Lopez, G., Gorenstein, D. G. & Sood, A. K., Jun 7 2018, In : JCI insight. 3, 11

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP)

Mitamura, T., Pradeep, S., McGuire, M., Wu, S., Ma, S., Hatakeyama, H., Lyons, Y. A., Hisamatsu, T., Noh, K., Villar-Prados, A., Chen, X., Ivan, C., Rodriguez-Aguayo, C., Hu, W., Lopez, G., Coleman, R. & Sood, A. K., Feb 8 2018, In : Oncogene. 37, 6, p. 722-731 10 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Neoplasms
Therapeutics
R Factors
Acetylation

Inhibiting nuclear phospho-progesterone receptor enhances antitumor activity of onapristone in uterine cancer

Huang, Y., Hu, W., Huang, J., Shen, F., Sun, Y., Ivan, C., Pradeep, S., Dood, R., Haemmerle, M., Jiang, D., Mangala, L. S., Noh, K., Hansen, J. M., Dalton, H. J., Previs, R. A., Nagaraja, A. S., McGuire, M., Jennings, N. B., Broaddus, R., Coleman, R. & 1 others, Sood, A. K., Feb 1 2018, In : Molecular cancer therapeutics. 17, 2, p. 464-473 10 p.

Research output: Contribution to journalArticle

Uterine Neoplasms
Progesterone Receptors
Epidermal Growth Factor
Ligands
onapristone
7 Citations (Scopus)

Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers

Yuan, J., Hu, Z., Mahal, B. A., Zhao, S. D., Kensler, K. H., Pi, J., Hu, X., Zhang, Y., Wang, Y., Jiang, J., Li, C., Zhong, X., Montone, K. T., Guan, G., Tanyi, J. L., Fan, Y., Xu, X., Morgan, M. A., Long, M., Zhang, Y. & 5 others, Zhang, R., Sood, A. K., Rebbeck, T. R., Dang, C. V. & Zhang, L., Oct 8 2018, In : Cancer Cell. 34, 4, p. 549-560.e9

Research output: Contribution to journalArticle

Chromosomal Instability
African Americans
Neoplasms
Endometrial Neoplasms
Head and Neck Neoplasms
8 Citations (Scopus)

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 213-226.e3

Research output: Contribution to journalArticle

Ubiquitin
Genes
Neoplasms
Tumors
Amplification