Anil K Sood – Research Output — MD Anderson Cancer Center

2018

6 Citations

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 690-705.e9

Research output: Contribution to journal › Article

Breast Neoplasms

Atlases

Long Noncoding RNA

Decision Trees

Genome

ADH1B promotes mesothelial clearance and ovarian cancer infiltration

Gharpure, K. M., Lara, O. D., Wen, Y., Pradeep, S., LaFargue, C., Ivan, C., Rupaimoole, R., Hu, W., Mangala, L. S., Wu, S., Nagaraja, A. S., Baggerly, K. A. & Sood, A. K., May 18 2018, In : Oncotarget. 9, 38, p. 25115-25126 12 p.

Research output: Contribution to journal › Article

Ovarian Neoplasms

Neoplasms

Adjuvant Chemotherapy

Cell Adhesion

Extracellular Matrix

12 Citations

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journal › Article

Atlases

Genes

Genome

Survival

Neoplasms

6 Citations

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 386-399.e12

Research output: Contribution to journal › Article

Genes

Tumors

Neoplasms

Computational methods

Chromatin

Association of biobehavioral factors with non-coding RNAs in cervical cancer

Liu, Q., Lu, C., Dai, W., Li, K., Xu, J., Huang, Y., Li, G., Kang, Y., Sood, A. K. & Xu, C., Jan 1 2018, In : BioScience Trends. 12, 1, p. 24-31 8 p.

Research output: Contribution to journal › Article

Long Noncoding RNA

Untranslated RNA

Uterine Cervical Neoplasms

cancer

Gene Ontology

3 Citations

A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression

Velazquez-Torres, G., Shoshan, E., Ivan, C., Huang, L., Fuentes-Mattei, E., Paret, H., Kim, S. J., Rodriguez-Aguayo, C., Xie, V., Brooks, D., Jones, S. J. M., Robertson, A. G., Calin, G. A., Lopez-Berenstein, G., Sood, A. K. & Bar Eli, M., Dec 1 2018, In : Nature communications. 9, 1, 461.

Research output: Contribution to journal › Article

editing

MicroRNAs

progressions

Melanoma

3' Untranslated Regions

Bioactive lipid metabolism in platelet “first responder” and cancer biology

Kanikarla Marie, P., Kopetz, E. S., Hawk, E., Millward, S., Sood, A. K., Gresele, P., Overman, M. J., Honn, K. & Menter, D. G., Sep 1 2018, In : Cancer and Metastasis Reviews. 37, 2-3, p. 439-454 16 p.

Research output: Contribution to journal › Article

Lipid Metabolism

Blood Platelets

Eicosanoids

Thromboxanes

Epoprostenol

3 Citations

Biobehavioral modulation of the exosome transcriptome in ovarian carcinoma

Lutgendorf, S. K., Thaker, P. H., Arevalo, J. M., Goodheart, M. J., Slavich, G. M., Sood, A. K. & Cole, S. W., Feb 1 2018, In : Cancer. 124, 3, p. 580-586 7 p.

Research output: Contribution to journal › Article

Exosomes

Transcriptome

Social Support

Activating Transcription Factors

Carcinoma

Bone protection by inhibition of microRNA-182

Inoue, K., Deng, Z., Chen, Y., Giannopoulou, E., Xu, R., Gong, S., Greenblatt, M. B., Mangala, L. S., Lopez, G., Kirsch, D. G., Sood, A. K., Zhao, L. & Zhao, B., Dec 1 2018, In : Nature communications. 9, 1, 4108.

Research output: Contribution to journal › Article

arthritis

Interferon-beta

interferon

MicroRNAs

Osteogenesis

6 Citations

Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance

Leung, S. L. C., Yeung, T-L., Yip, K. P., Wong, K. K., Ho, S. Y., Mangala, L. S., Sood, A. K., Lopez, G., Sheng, J., Wong, S. T. C., Birrer, M. J. & Mok, S., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 589-606 18 p.

Research output: Contribution to journal › Article

Lipoma

Ovarian Neoplasms

Proteins

Endothelial Cells

Small Interfering RNA

CD44-targeting PLGA nanoparticles incorporating paclitaxel and FAK siRNA overcome chemoresistance in epithelial ovarian cancer

Byeon, Y., Lee, J. W., Choi, W. S., Won, J. E., Kim, G. H., Kim, M. G., Wi, T. I., Lee, J. M., Kang, T. H., Jung, I. D., Cho, Y. J., Ahn, H. J., Shin, B. C., Lee, Y. J., Sood, A. K., Han, H. D. & Park, Y. M., Nov 1 2018, In : Cancer Research. 78, 21, p. 6247-6256 10 p.

Research output: Contribution to journal › Article

Focal Adhesion Protein-Tyrosine Kinases

Paclitaxel

Nanoparticles

Small Interfering RNA

Ovarian Neoplasms

21 Citations

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

The Cancer Genome Atlas Network, Apr 5 2018, In : Cell. 173, 2, p. 291-304.e6

Research output: Contribution to journal › Article

Tumors

Tissue

Histology

Methylation

Oncology

8 Citations

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 721-735.e8

Research output: Contribution to journal › Article

Adenocarcinoma

Neoplasms

Genome

Chromosomal Instability

Rectum

33 Citations

Comprehensive Characterization of Cancer Driver Genes and Mutations

The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 371-385.e18

Research output: Contribution to journal › Article

Neoplasm Genes

Tumors

Genes

Mutation

Neoplasms

Concordance of a laparoscopic scoring algorithm with primary surgery findings in advanced stage ovarian cancer

Hansen, J. M., Sood, A. K., Coleman, R., Westin, S. N., Soliman, P. T., Ramirez, P. T., Fellman, B. M., Schmeler, K. M. & Fleming, N., Jan 1 2018, (Accepted/In press) In : Gynecologic oncology.

Research output: Contribution to journal › Article

Ovarian Neoplasms

Laparoscopy

Neoplasms

Stomach Diseases

Diaphragm

Defining Survivorship Trajectories Across Patients With Solid Tumors: An Evidence-Based Approach

Dood, R. L., Zhao, Y., Armbruster, S. D., Coleman, R., Tworoger, S., Sood, A. K. & Baggerly, K. A., Nov 1 2018, In : JAMA Oncology. 4, 11, p. 1519-1526 8 p.

Research output: Contribution to journal › Article

Survival Rate

Neoplasms

Mortality

Population

Primary Care Physicians

7 Citations

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 227-238.e3

Research output: Contribution to journal › Article

Human Development

Phosphotransferases

Genes

Gene expression

Tumors

5 Citations

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 194-212.e6

Research output: Contribution to journal › Article

Squamous Cell Carcinoma

MicroRNAs

Mutation

Epithelial Cells

Squamous Cell Neoplasms

10 Citations

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 676-689.e3

Research output: Contribution to journal › Article

Aneuploidy

Chromosomes

Neoplasms

Genome

Mutation Rate

12 Citations

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 239-254.e6

Research output: Contribution to journal › Article

DNA Repair-Deficiency Disorders

Atlases

DNA Damage

Repair

Genes

1 Citations

HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway

Liu, Y., Choi, D. S., Sheng, J., Ensor, J. E., Liang, D. H., Rodriguez-Aguayo, C., Polley, A., Benz, S., Elemento, O., Verma, A., Cong, Y., Wong, H., Qian, W., Li, Z., Granados-Principal, S., Lopez, G., Landis, M. D., Rosato, R. R., Dave, B., Wong, S. & 3 othersMarchetti, D., Sood, A. K. & Chang, J. C., Jan 1 2018, In : Stem Cell Reports. 10, 1, p. 212-227 16 p.

Research output: Contribution to journal › Article

Triple Negative Breast Neoplasms

Neoplastic Stem Cells

Stem cells

Breast Neoplasms

Transcription

1 Citations

Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma

Matsuo, K., Wong, K. K., Fotopoulou, C., Blake, E. A., Robertson, S. E., Pejovic, T., Frimer, M., Pardeshi, V., Hu, W., Choi, J. S., Sun, C. C., Richmond, A. M., Marcus, J. Z., Hilliard, M. A. M., Mostofizadeh, S., Mhawech-Fauceglia, P., Abdulfatah, E., Post, M. D., Saglam, O., Shahzad, M. M. K. & 6 othersKarabakhtsian, R. G., Ali-Fehmi, R., Gabra, H., Roman, L. D., Sood, A. K. & Gershenson, D. M., Feb 1 2018, In : Journal of surgical oncology. 117, 2, p. 236-244 9 p.

Research output: Contribution to journal › Article

Blood Vessels

Carcinoma

Survival

Neoplasms

Odds Ratio

1 Citations

Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP)

Mitamura, T., Pradeep, S., McGuire, M., Wu, S. Y., Ma, S., Hatakeyama, H., Lyons, Y. A., Hisamatsu, T., Noh, K., Villar-Prados, A., Chen, X., Ivan, C., Rodriguez-Aguayo, C., Hu, W., Lopez, G., Coleman, R. & Sood, A. K., Feb 8 2018, In : Oncogene. 37, 6, p. 722-731 10 p.

Research output: Contribution to journal › Article

Vascular Endothelial Growth Factor A

Neoplasms

Therapeutics

R Factors

Acetylation

Inhibiting nuclear phospho-progesterone receptor enhances antitumor activity of onapristone in uterine cancer

Huang, Y., Hu, W., Huang, J., Shen, F., Sun, Y., Ivan, C., Pradeep, S., Dood, R., Haemmerle, M., Jiang, D., Mangala, L. S., Noh, K., Hansen, J. M., Dalton, H. J., Previs, R. A., Nagaraja, A. S., McGuire, M., Jennings, N. B., Broaddus, R., Coleman, R. & 1 othersSood, A. K., Feb 1 2018, In : Molecular Cancer Therapeutics. 17, 2, p. 464-473 10 p.

Research output: Contribution to journal › Article

Uterine Neoplasms

Progesterone Receptors

Epidermal Growth Factor

Ligands

onapristone

1 Citations

Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers

Yuan, J., Hu, Z., Mahal, B. A., Zhao, S. D., Kensler, K. H., Pi, J., Hu, X., Zhang, Y., Wang, Y., Jiang, J., Li, C., Zhong, X., Montone, K. T., Guan, G., Tanyi, J. L., Fan, Y., Xu, X., Morgan, M. A., Long, M., Zhang, Y. & 5 othersZhang, R., Sood, A. K., Rebbeck, T. R., Dang, C. V. & Zhang, L., Oct 8 2018, In : Cancer Cell. 34, 4, p. 549-560.e9

Research output: Contribution to journal › Article

Chromosomal Instability

African Americans

Neoplasms

Endometrial Neoplasms

Head and Neck Neoplasms

3 Citations

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 213-226.e3

Research output: Contribution to journal › Article

Ubiquitin

Genes

Neoplasms

Tumors

Amplification

Laparoscopic Surgical Algorithm to Triage the Timing of Tumor Reductive Surgery in Advanced Ovarian Cancer

Fleming, N., Nick, A. M., Coleman, R., Westin, S. N., Ramirez, P. T., Soliman, P. T., Fellman, B., Meyer, L. A., Schmeler, K. M., Lu, K. H. & Sood, A. K., Jan 1 2018, In : Obstetrics and gynecology. 132, 3, p. 545-554 10 p.

Research output: Contribution to journal › Article

Triage

Ovarian Neoplasms

Neoplasms

Drug Therapy

Disease-Free Survival

Life stress as a risk factor for sustained anxiety and cortisol dysregulation during the first year of survivorship in ovarian cancer

Armer, J. S., Clevenger, L., Davis, L. Z., Cuneo, M., Thaker, P. H., Goodheart, M. J., Bender, D. P., Dahmoush, L., Sood, A. K., Cole, S. W., Slavich, G. M. & Lutgendorf, S. K., Aug 1 2018, In : Cancer. 124, 16, p. 3401-3408 8 p.

Research output: Contribution to journal › Article

Psychological Stress

Ovarian Neoplasms

Hydrocortisone

Survival Rate

Anxiety

13 Citations

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 706-720.e9

Research output: Contribution to journal › Article

Long Noncoding RNA

Epigenomics

Cell Cycle

Genes

Neoplasms

2 Citations

Lpa induces metabolic reprogramming in ovarian cancer via a pseudohypoxic response

Ha, J. H., Radhakrishnan, R., Jayaraman, M., Yan, M., Ward, J. D., Fung, K. M., Moxley, K., Sood, A. K., Isidoro, C., Mukherjee, P., Song, Y. S. & Dhanasekaran, D. N., Apr 15 2018, In : Cancer Research. 78, 8, p. 1923-1934 12 p.

Research output: Contribution to journal › Article

Ovarian Neoplasms

Hexokinase

Facilitative Glucose Transport Proteins

NADPH Oxidase

Protein Subunits

6 Citations

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 172-180.e3

Research output: Contribution to journal › Article

Atlases

Learning systems

Tumors

Genes

Chemical activation

14 Citations

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 338-354.e15

Research output: Contribution to journal › Article

Learning systems

Tumors

Neoplasms

Stem cells

Logistics

3 Citations

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 255-269.e4

Research output: Contribution to journal › Article

Tumors

Carbohydrates

Oncology

Metabolism

Vitamins

4 Citations

MYC targeted long noncoding RNA DANCR promotes cancer in part by reducing p21 levels

Lu, Y., Hu, Z., Mangala, L. S., Stine, Z. E., Hu, X., Jiang, D., Xiang, Y., Zhang, Y., Pradeep, S., Rodriguez-Aguayo, C., Lopez, G., DeMarzo, A. M., Sood, A. K., Zhang, L. & Dang, C. V., Jan 1 2018, In : Cancer Research. 78, 1, p. 64-74 11 p.

Research output: Contribution to journal › Article

Long Noncoding RNA

Neoplasms

Cell Proliferation

Ovarian Neoplasms

Modifier Genes

26 Citations

Oncogenic Signaling Pathways in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 321-337.e10

Research output: Contribution to journal › Article

Atlases

Tumors

Genes

Genome

Neoplasms

Paclitaxel sensitivity of ovarian cancer can be enhanced by knocking down pairs of kinases that regulate MAP4 phosphorylation and microtubule stability

Yang, H., Mao, W., Rodriguez-Aguayo, C., Mangala, L. S., Bartholomeusz, G., Iles, L. R., Jennings, N. B., Ahmed, A. A., Sood, A. K., Lopez, G., Lu, Z. & Bast Jr, R. C., Oct 15 2018, In : Clinical Cancer Research. 24, 20, p. 5072-5084 13 p.

Research output: Contribution to journal › Article

Paclitaxel

Microtubules

Ovarian Neoplasms

Phosphotransferases

Phosphorylation

4 Citations

Paclitaxel with and without pazopanib for persistent or recurrent ovarian cancer: A randomized clinical trial

Richardson, D. L., Sill, M. W., Coleman, R., Sood, A. K., Pearl, M. L., Kehoe, S. M., Carney, M. E., Hanjani, P., Van Le, L., Zhou, X. C., Secord, A. A., Gray, H. J., Landrum, L. M., Lankes, H. A., Hu, W. & Aghajanian, C., Feb 1 2018, In : JAMA Oncology. 4, 2, p. 196-202 7 p.

Research output: Contribution to journal › Article

Paclitaxel

Ovarian Neoplasms

Randomized Controlled Trials

Disease-Free Survival

Survival

9 Citations

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

The Cancer Genome Atlas Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 282-300.e2

Research output: Contribution to journal › Article

Atlases

Oncogenes

Genome

Neoplasms

Neoplasm Genes

10 Citations

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 297-312.e12

Research output: Contribution to journal › Article

Long Noncoding RNA

Neoplasm Genes

Tumors

Genes

Neoplasms

8 Citations

Pathogenic Germline Variants in 10,389 Adult Cancers

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 355-370.e14

Research output: Contribution to journal › Article

Gene expression

Automatic teller machines

Tumors

Neoplasms

Genes

Perineural invasion (PNI) in vulvar carcinoma: A review of 421 cases

Salcedo, M. P., Sood, A. K., dos Reis, R., Ramalingam, P., Chen, C., Frumovitz, M., Jhingran, A., Pitcher, B., Ramirez, P. T. & Schmeler, K. M., Jan 1 2018, (Accepted/In press) In : Gynecologic oncology.

Research output: Contribution to journal › Article

Vulvar Neoplasms

Carcinoma

Disease-Free Survival

Lichen Sclerosus et Atrophicus

Survival

1 Citations

Perioperative inhibition of β-adrenergic and COX2 signaling in a clinical trial in breast cancer patients improves tumor Ki-67 expression, serum cytokine levels, and PBMCs transcriptome

Haldar, R., Shaashua, L., Lavon, H., Lyons, Y. A., Zmora, O., Sharon, E., Birnbaum, Y., Allweis, T., Sood, A. K., Barshack, I., Cole, S. & Ben-Eliyahu, S., Oct 1 2018, In : Brain, behavior, and immunity. 73, p. 294-309 16 p.

Research output: Contribution to journal › Article

Transcriptome

Adrenergic Agents

Clinical Trials

Breast Neoplasms

Cytokines

6 Citations

Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy

Moruno-Manchon, J. F., Uzor, N. E., Kesler, S., Wefel, J. S., Townley, D. M., Nagaraja, A. S., Pradeep, S., Mangala, L. S., Sood, A. K. & Tsvetkov, A. S., Jan 1 2018, In : Molecular and Cellular Neuroscience. 86, p. 65-71 7 p.

Research output: Contribution to journal › Article

Peroxisomes

Doxorubicin

Oxidative Stress

Neurons

Drug Therapy

7 Citations

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 305-320.e10

Research output: Contribution to journal › Article

Genomics

Tumors

Genes

Neoplasms

Atlases

6 Citations

RNA interference-based therapy and its delivery systems

Chen, X., Mangala, L. S., Rodriguez-Aguayo, C., Kong, X., Lopez, G. & Sood, A. K., Mar 1 2018, In : Cancer and Metastasis Reviews. 37, 1, p. 107-124 18 p.

Research output: Contribution to journal › Article

RNA Interference

Gene Silencing

Therapeutics

Virus Diseases

MicroRNAs

13 Citations

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 271-281.e7

Research output: Contribution to journal › Article

Exome

Mutation

Atlases

Neoplasms

Genomics

1 Citations

Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer

Kim, G. H., Won, J. E., Byeon, Y., Kim, M. G., Wi, T. I., Lee, J. M., Park, Y. Y., Lee, J. W., Kang, T. H., Jung, I. D., Shin, B. C., Ahn, H. J., Lee, Y. J., Sood, A. K., Han, H. D. & Park, Y. M., Jan 1 2018, In : Drug Delivery. 25, 1, p. 1394-1402 9 p.

Research output: Contribution to journal › Article

Chitosan

Nanoparticles

Small Interfering RNA

Endothelial Cells

Hyaluronic Acid

10 Citations

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 282-296.e4

Research output: Contribution to journal › Article

Genes

Mutation

Neoplasms

Tumors

RNA

7 Citations

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 181-193.e7

Research output: Contribution to journal › Article

Tumor-Infiltrating Lymphocytes

Lymphocytes

Pathology

Tumors

Learning

Stress, inflammation, and eicosanoids: an emerging perspective

Umamaheswaran, S., Dasari, S. K., Yang, P., Lutgendorf, S. K. & Sood, A. K., Sep 1 2018, In : Cancer and Metastasis Reviews. 37, 2-3, p. 203-211 9 p.

Research output: Contribution to journal › Article

Eicosanoids

Inflammation

Metabolic Networks and Pathways

Adrenergic Agents

Neoplasms