Bin Liu

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CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells
Rafei, H., Basar, R., Acharya, S., Hsu, Y. S., Liu, P., Zhang, D., Bohn, T., Liang, Q., Mohanty, V., Upadhyay, R., Li, P., Phadatare, P., Dede, M., Xiong, D., Fan, H., Jones, C. M., Kunz, S., Daher, M., Nunez Cortes, A. K. & Shanley, M. & 38 others, Liu, B., Moseley, S. M., Zhang, C., Fang, D., Banerjee, P., Uprety, N., Li, Y., Shrestha, R., Wan, X., Shen, H., Woods, V., Gilbert, A. L., Rawal, S., Dou, J., Tan, Y., Park, J. M., Reyes Silva, F., Biederstädt, A., Kaplan, M., Jiang, X. R., Biederstädt, I., Kumar, B., Tiberti, S., Moore, M., Jin, J., Yang, R. Z., Muniz-Feliciano, L., Rosemore, S., Lin, P., Deyter, G. M., Fowlkes, N. W., Jain, A. K., Marin, D., Maitra, A., Chen, K., Bopp, T., Shpall, E. J. & Rezvani, K., Jul 24 2025, In: Nature. 643, 8073, p. 1076-1086 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
25 Link opens in a new tab Scopus citations
Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency
Biederstädt, A., Basar, R., Park, J. M., Uprety, N., Shrestha, R., Reyes Silva, F., Dede, M., Watts, J., Acharya, S., Xiong, D., Liu, B., Daher, M., Rafei, H., Banerjee, P., Li, P., Islam, S., Fan, H., Shanley, M., Jin, J. & Kumar, B. & 16 others, Woods, V., Lin, P., Tiberti, S., Nunez Cortes, A. K., Jiang, X. R., Biederstädt, I., Zhang, P., Li, Y., Rawal, S., Liu, E., Muniz-Feliciano, L., Deyter, G. M., Shpall, E. J., Fowlkes, N. W., Chen, K. & Rezvani, K., Nov 10 2025, In: Cancer cell. 43, 11, p. 2069-2088.e11
Research output: Contribution to journal › Article › peer-review

Open Access
16 Link opens in a new tab Scopus citations
CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ ZAP70 Signaling Axis
Acharya, S., Basar, R., Daher, M., Rafei, H., Li, P., Uprety, N., Ensley, E., Shanley, M., Kumar, B., Banerjee, P. P., Garcia, L. M., Lin, P., Mohanty, V., Kim, K. H., Jiang, X., Pan, Y., Li, Y., Liu, B., Nunez Cortes, A. K. & Zhang, C. & 27 others, Fathi, M., Rezvan, A., Montalvo, M. J., Cha, S. L., Reyes-Silva, F., Shrestha, R., Guo, X., Kundu, K., Biederstädt, A., Muniz-Feliciano, L., Deyter, G. M., Kaplan, M., Jiang, X. R., Liu, E., Jain, A., Roszik, J., Fowlkes, N. W., Solis Soto, L. M., Raso, M. G., Khoury, J. D., Lin, P., Vega, F., Varadarajan, N., Chen, K., Marin, D., Shpall, E. J. & Rezvani, K., Oct 1 2024, In: Cancer discovery. 14, 10, p. 1879-1900 22 p.
Research output: Contribution to journal › Article › peer-review

Open Access
38 Link opens in a new tab Scopus citations
Correction to: KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape (Nature Medicine, (2022), 28, 10, (2133-2144), 10.1038/s41591-022-02003-x)
Li, Y., Basar, R., Wang, G., Liu, E., Moyes, J. S., Li, L., Kerbauy, L. N., Uprety, N., Fathi, M., Rezvan, A., Banerjee, P. P., Muniz-Feliciano, L., Laskowski, T. J., Ensley, E., Daher, M., Shanley, M., Mendt, M., Acharya, S., Liu, B. & Biederstädt, A. & 12 others, Rafei, H., Guo, X., Melo Garcia, L., Lin, P., Ang, S., Marin, D., Chen, K., Bover, L., Champlin, R. E., Varadarajan, N., Shpall, E. J. & Rezvani, K., Mar 2024, In: Nature medicine. 30, 3, p. 906 1 p.
Research output: Contribution to journal › Comment/debate › peer-review

Open Access
2 Link opens in a new tab Scopus citations
KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape
Li, Y., Basar, R., Wang, G., Liu, E., Moyes, J. S., Li, L., Kerbauy, L. N., Uprety, N., Fathi, M., Rezvan, A., Banerjee, P. P., Muniz-Feliciano, L., Laskowski, T. J., Ensley, E., Daher, M., Shanley, M., Mendt, M., Acharya, S., Liu, B. & Biederstädt, A. & 12 others, Rafei, H., Guo, X., Melo Garcia, L., Lin, P., Ang, S., Marin, D., Chen, K., Bover, L., Champlin, R. E., Varadarajan, N., Shpall, E. J. & Rezvani, K., Oct 2022, In: Nature medicine. 28, 10, p. 2133-2144 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
151 Link opens in a new tab Scopus citations

Bin Liu

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Collaborations and top research areas from the last five years

Dive into details

CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells

Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency

CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ ZAP70 Signaling Axis

Correction to: KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape (Nature Medicine, (2022), 28, 10, (2133-2144), 10.1038/s41591-022-02003-x)

KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape

Bin Liu

Fingerprint

Collaborations and top research areas from the last five years

Research output

CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells

Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency

CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ ZAP70 Signaling Axis

Correction to: KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape (Nature Medicine, (2022), 28, 10, (2133-2144), 10.1038/s41591-022-02003-x)

KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape