• 8155 Citations
  • 46 h-Index
1978 …2018
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Fingerprint Dive into the research topics where Bruno Kyewski is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Thymus Gland Medicine & Life Sciences
Autoantigens Medicine & Life Sciences
Thymocytes Medicine & Life Sciences
Antigens Medicine & Life Sciences
Stromal Cells Medicine & Life Sciences
Central Tolerance Medicine & Life Sciences

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Research Output 1978 2018

An efficient protocol for in vivo labeling of proliferating epithelial cells

Michel, C., Küchler, R., Martin, I., Kyewski, B. & Pinto, S., Jun 1 2018, In : Journal of Immunological Methods. 457, p. 82-86 5 p.

Research output: Contribution to journalArticle

Epithelial Cells
Cell Differentiation
Cell Proliferation
Single-Cell Analysis
Organogenesis
15 Citations (Scopus)

Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors

Gonzalez-Duque, S., Azoury, M. E., Colli, M. L., Afonso, G., Turatsinze, J. V., Nigi, L., Lalanne, A. I., Sebastiani, G., Carré, A., Pinto, S., Culina, S., Corcos, N., Bugliani, M., Marchetti, P., Armanet, M., Diedisheim, M., Kyewski, B., Steinmetz, L. M., Buus, S., You, S. & 10 others, Dubois-Laforgue, D., Larger, E., Beressi, J. P., Bruno, G., Dotta, F., Scharfmann, R., Eizirik, D. L., Verdier, Y., Vinh, J. & Mallone, R., Dec 4 2018, In : Cell Metabolism. 28, 6, p. 946-960.e6

Research output: Contribution to journalArticle

Epitopes
Tissue Donors
T-Lymphocytes
Type 1 Diabetes Mellitus
Peptides
21 Citations (Scopus)

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

ImMaDiab Study Group, Jan 1 2018, In : Science Immunology. 3, 20, eaao4013.

Research output: Contribution to journalArticle

Pancreas
Type 1 Diabetes Mellitus
Tissue Donors
T-Lymphocytes
Epitopes
11 Citations (Scopus)

T cells specific for post-translational modifications escape intrathymic tolerance induction

Raposo, B., Merky, P., Lundqvist, C., Yamada, H., Urbonaviciute, V., Niaudet, C., Viljanen, J., Kihlberg, J., Kyewski, B., Ekwall, O., Holmdahl, R. & Bäcklund, J., Dec 1 2018, In : Nature communications. 9, 1, 353.

Research output: Contribution to journalArticle

T-cells
antigens
Post Translational Protein Processing
Central Tolerance
escape
19 Citations (Scopus)

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

Miller, C. N., Proekt, I., von Moltke, J., Wells, K. L., Rajpurkar, A. R., Wang, H., Rattay, K., Khan, I. S., Metzger, T. C., Pollack, J. L., Fries, A. C., Lwin, W. W., Wigton, E. J., Parent, A. V., Kyewski, B., Erle, D. J., Hogquist, K. A., Steinmetz, L. M., Locksley, R. M. & Anderson, M. S., Jul 26 2018, In : Nature. 559, 7715, p. 627-631 5 p.

Research output: Contribution to journalLetter

Thymocytes
Interleukin-4
Epithelial Cells
Natural Killer T-Cells
Aptitude