Dimpy Koul

Associate Professor

  • 3246 Citations
  • 29 h-Index
1992 …2019
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  • 6 Similar Profiles
Glioblastoma Medicine & Life Sciences
Glioma Medicine & Life Sciences
Phosphatidylinositol 3-Kinase Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Tumor Suppressor Genes Medicine & Life Sciences
Growth Medicine & Life Sciences
Apoptosis Medicine & Life Sciences

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Research Output 1992 2019

  • 3246 Citations
  • 29 h-Index
  • 47 Article
  • 1 Comment/debate
  • 1 Review article
7 Citations (Scopus)

Buparlisib in patients with recurrent glioblastoma harboring phosphatidylinositol 3-kinase pathway activation: An open-label, multicenter, multi-arm, phase II trial

Wen, P. Y., Touat, M., Alexander, B. M., Mellinghoff, I. K., Ramkissoon, S., McCluskey, C. S., Pelton, K., Haidar, S., Basu, S. S., Gaffey, S. C., Brown, L. E., Martinez-Ledesma, J. E., Wu, S., Kim, J., Wei, W., Park, M. A., Huse, J., Kuhn, J. G., Rinne, M. L., Colman, H. & 24 others, Agar, N. Y. R., Omuro, A. M., DeAngelis, L. M., Gilbert, M. R., de Groot, J. F., Cloughesy, T. F., Chi, A. S., Roberts, T. M., Zhao, J. J., Lee, E. Q., Nayak, L., Heath, J. R., Horky, L. L., Batchelor, T. T., Beroukhim, R., Chang, S. M., Ligon, A. H., Dunn, I. F., Koul, D., Young, G. S., Prados, M. D., Reardon, D. A., Alfred Yung, W. K. & Ligon, K. L., Mar 20 2019, In : Journal of Clinical Oncology. 37, 9, p. 741-750 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Glioblastoma
Neoplasms
Pharmacokinetics
NVP-BKM120

TIE2–FGFR1 interaction induces adaptive PI3K inhibitor resistance by upregulating Aurora A/PlK1/CDK1 signaling in glioblastoma

Li, X., Martinez-Ledesma, E., Zhang, C., Gao, F., Zheng, S., Ding, J., Wu, S., Nguyen, N., Clifford, S. C., Wen, P. Y., Ligon, K. L., Alfred Yung, W. K. & Koul, D., Oct 1 2019, In : Cancer research. 79, 19, p. 5088-5101 14 p.

Research output: Contribution to journalArticle

Glioblastoma
Phosphatidylinositol 3-Kinases
Phosphotransferases
Aurora Kinase A
Heterografts
4 Citations (Scopus)

Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma

Wu, S., Wang, S., Gao, F., Li, L., Zheng, S., Yung, W. K. A. & Koul, D., Jan 1 2018, In : Neuro-oncology. 20, 1, p. 78-91 14 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Glioblastoma
Heterografts
Cell Division
Neoplasms
3 Citations (Scopus)

APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death

Wang, Y., Wu, S., Zheng, S., Wang, S., Wali, A., Ezhilarasan, R., Sulman, E. P., Koul, D. & Alfred Yung, W. K., Jan 1 2017, In : Oncotarget. 8, 33, p. 54285-54296 12 p.

Research output: Contribution to journalArticle

Glioma
Cell Death
Radiation
Therapeutics
Genes
4 Citations (Scopus)

PAF promotes stemness and radioresistance of glioma stem cells

Ong, D. S. T., Hu, B., Ho, Y. W., Sauvé, C. E. G., Bristow, C. A., Wang, Q., Multani, A. S., Chen, P., Nezi, L., Jiang, S., Gorman, C. E., Moreno Monasterio, M., Koul, D., Marchesini, M., Colla, S., Jin, E. J., Sulman, E. P., Spring, D. J., Yung, W. K. A., Verhaak, R. G. W. & 3 others, Chin, L., Wang, Y. A. & DePinho, R. A., Oct 24 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 43, p. E9085-E9095

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
Glioma
Stem Cells
Glioblastoma
DNA Replication