• 13770 Citations
  • 60 h-Index
1986 …2019
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Research Output 1986 2019

2019
2 Citations (Scopus)

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer

Walsh, N., Zhang, H., Hyland, P. L., Yang, Q., Mocci, E., Zhang, M., Childs, E. J., Collins, I., Wang, Z., Arslan, A. A., Beane-Freeman, L., Bracci, P. M., Brennan, P., Canzian, F., Duell, E. J., Gallinger, S., Giles, G. G., Goggins, M., Goodman, G. E., Goodman, P. J. & 78 others, Hung, R. J., Kooperberg, C., Kurtz, R. C., Malats, N., Lemarchand, L., Neale, R. E., Olson, S. H., Scelo, G., Shu, X. O., Van Den Eeden, S. K., Visvanathan, K., White, E., Zheng, W., Albanes, D., Andreotti, G., Babic, A., Bamlet, W. R., Berndt, S. I., Borgida, A., Boutron-Ruault, M. C., Brais, L., Bueno-De-Mesquita, B., Buring, J., Chaffee, K. G., Chanock, S., Cleary, S., Cotterchio, M., Foretova, L., Fuchs, C., M Gaziano, J. M., Giovannucci, E., Hackert, T., Haiman, C., Hartge, P., Hasan, M., Helzlsouer, K. J., Herman, J., Holcatova, I., Holly, E. A., Hoover, R., Janout, V., Klein, E. A., Laheru, D., Lee, I. M., Lu, L., Mannisto, S., Milne, R. L., Oberg, A. L., Orlow, I., Patel, A. V., Peters, U., Porta, M., Real, F. X., Rothman, N., Sesso, H. D., Severi, G., Silverman, D., Strobel, O., Sund, M., Thornquist, M. D., Tobias, G. S., Wactawski-Wende, J., Wareham, N., Weiderpass, E., Wentzensen, N., Wheeler, W., Yu, H., Zeleniuch-Jacquotte, A., Kraft, P., Li, D., Jacobs, E. J., Petersen, G. M., Wolpin, B. M., Risch, H. A., Amundadottir, L. T., Yu, K., Klein, A. P. & Stolzenberg-Solomon, R. Z., Jun 1 2019, In : Journal of the National Cancer Institute. 111, 6, p. 557-567 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pancreatic Neoplasms
Genes
Single Nucleotide Polymorphism
Adenocarcinoma

A GPC1-targeted and gemcitabine-loaded biocompatible nanoplatform for pancreatic cancer multimodal imaging and therapy

Qiu, W., Zhang, H., Chen, X., Song, L., Cui, W., Ren, S., Wang, Y., Guo, K., Li, D., Chen, R. & Wang, Z., Jan 1 2019, In : Nanomedicine. 14, 17, p. 2339-2353 15 p.

Research output: Contribution to journalArticle

gemcitabine
Multimodal Imaging
Pancreatic Neoplasms
Nanoparticles
Imaging techniques
2 Citations (Scopus)

Analysis of heritability and genetic architecture of pancreatic cancer: A PANC4 study

Chen, F., Childs, E. J., Mocci, E., Bracci, P., Gallinger, S., Li, D., Neale, R. E., Olson, S. H., Scelo, G., Bamlet, W. R., Blackford, A. L., Borges, M., Brennan, P., Chaffee, K. G., Duggal, P., Hassan, M. J., Holly, E. A., Hung, R. J., Goggins, M. G., Kurtz, R. C. & 6 others, Oberg, A. L., Orlow, I., Yu, H., Petersen, G. M., Risch, H. A. & Klein, A. P., Jan 1 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 7, p. 1238-1245 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Genome-Wide Association Study
Genome
Neoplasm Genes
Linkage Disequilibrium
3 Citations (Scopus)

A powerful and data-adaptive test for rare-variant–based gene-environment interaction analysis

Yang, T., Chen, H., Tang, H. W., Li, D. & Wei, P., Mar 30 2019, In : Statistics in Medicine. 38, 7, p. 1230-1244 15 p.

Research output: Contribution to journalArticle

Gene-environment Interaction
Adaptive Test
Exome
Gene-Environment Interaction
Genetic Testing

Association between birth weight and diabetes: Role of body mass index and lifestyle in later life

for the REACTION Study Group, Jan 1 2019, (Accepted/In press) In : Journal of Diabetes.

Research output: Contribution to journalArticle

Birth Weight
Life Style
Body Mass Index
Confidence Intervals
Odds Ratio
1 Citation (Scopus)

Dietary N-nitroso compounds and risk of pancreatic cancer: Results from a large case-control study

Zheng, J., Stuff, J., Tang, H., Hassan, M. M., Daniel, C. R. & Li, D., Jan 1 2019, In : Carcinogenesis. 40, 2, p. 254-262 9 p.

Research output: Contribution to journalArticle

Nitroso Compounds
Pancreatic Neoplasms
Case-Control Studies
Dimethylnitrosamine
Diethylnitrosamine

Erratum: Downregulation of human endogenous retrovirus type K (HERV-K) viral Env RNA in pancreatic cancer cells decreases cell proliferation and tumor growth (Clin Cancer Res. ( 2017)23:19(5892-5911) DOI: 10.1158/1078-0432.CCR-17-0001)

Li, M., Radvanyi, L., Yin, B., Rycaj, K., Li, J., Chivukula, R., Lin, K., Lu, Y., Shen, J. J., Chang, D. Z., Li, D., Johanning, G. L. & Wang-Johanning, F., Jan 1 2019, In : Clinical Cancer Research. 25, 9, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Endogenous Retroviruses
Viral RNA
Pancreatic Neoplasms
Down-Regulation
Cell Proliferation
2 Citations (Scopus)

Ideal Cardiovascular Health Metrics and Major Cardiovascular Events in Patients with Prediabetes and Diabetes

Wang, T., Lu, J., Su, Q., Chen, Y., Bi, Y., Mu, Y., Chen, L., Hu, R., Tang, X., Yu, X., Li, M., Xu, M., Xu, Y., Zhao, Z., Yan, L., Qin, G., Wan, Q., Chen, G., Dai, M., Zhang, D. & 22 others, Gao, Z., Wang, G., Shen, F., Luo, Z., Qin, Y., Chen, L., Huo, Y., Li, Q., Ye, Z., Zhang, Y., Liu, C., Wang, Y., Wu, S., Yang, T., Deng, H., Li, D., Lai, S., Bloomgarden, Z. T., Shi, L., Ning, G., Zhao, J. & Wang, W., Sep 2019, In : JAMA Cardiology. 4, 9, p. 874-883 10 p.

Research output: Contribution to journalArticle

Prediabetic State
Health
Cardiovascular Diseases
Glucose
China
2 Citations (Scopus)

Predictive value of fasting glucose, postload glucose, and hemoglobin A1c on risk of diabetes and complications in Chinese adults

4C Study Group, Aug 1 2019, In : Diabetes care. 42, 8, p. 1539-1548 10 p.

Research output: Contribution to journalArticle

Diabetes Complications
Fasting
Hemoglobins
Glucose
Cardiovascular Diseases

血清载脂蛋白B与中国中老年人代谢综合征风险增加相关:一项横断面和前瞻性队列研究

Translated title of the contribution: Serum apolipoprotein B is associated with increased risk of metabolic syndrome among middle-aged and elderly Chinese: A cross-sectional and prospective cohort studyDu, R., Wu, X., Peng, K., Lin, L., Li, M., Xu, Y., Xu, M., Chen, Y., Li, D., Lu, J., Bi, Y., Wang, W. & Ning, G., Jan 1 2019, In : Journal of Diabetes. 11, 9, p. 752-760 9 p.

Research output: Contribution to journalArticle

Apolipoproteins B
Cohort Studies
Prospective Studies
Serum
Odds Ratio
1 Citation (Scopus)

静息心率与代谢综合征及10年心血管疾病的预测风险相关:一项横断面研究

Translated title of the contribution: Resting heart rate is associated with metabolic syndrome and predicted 10-year risk of cardiovascular disease: a cross-sectional studyWu, X., Du, R., Hu, C., Cheng, D., Ma, L., Li, M., Xu, Y., Xu, M., Chen, Y., Li, D., Bi, Y., Wang, W., Ning, G. & Lu, J., Nov 1 2019, In : Journal of Diabetes. 11, 11, p. 884-894 11 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Cross-Sectional Studies
Heart Rate
Hypertension
Abdominal Obesity
2018
8 Citations (Scopus)

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

Wang, Y. N., Lee, H. H., Chou, C. K., Yang, W. H., Wei, Y., Chen, C. T., Yao, J., Hsu, J. L., Zhu, C., Ying, H., Ye, Y., Wang, W. J., Lim, S. O., Xia, W., Ko, H. W., Liu, X., Liu, C. G., Wu, X., Wang, H., Li, D. & 9 others, Prakash, L. R., Katz, M. H., Kang, Y., Kim, M., Fleming, J. B., Fogelman, D., Javle, M., Maitra, A. & Hung, M. C., Apr 9 2018, In : Cancer cell. 33, 4, p. 752-769.e8

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Epidermal Growth Factor Receptor
Biomarkers
Ligands
Serum
4 Citations (Scopus)
Longitudinal Studies
Smoking
Neoplasms
Smoking Cessation
Logistic Models
1 Citation (Scopus)

CDKN2A germline rare coding variants and risk of pancreatic cancer in minority populations

McWilliams, R. R., Wieben, E. D., Chaffee, K. G., Antwi, S. O., Raskin, L., Olopade, O. I., Li, D., Highsmith, W. E., Colon-Otero, G., Khanna, L. G., Permuth, J. B., Olson, J. E., Frucht, H., Genkinger, J., Zheng, W., Blot, W. J., Wu, L., Almada, L. L., Fernandez-Zapico, M. E., Sicotte, H. & 2 others, Pedersen, K. S. & Petersen, G. M., Nov 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 11, p. 1364-1370 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
African Americans
Population
Odds Ratio
Confidence Intervals

Clinical and prognostic significance of circulating levels of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma

Pestana, R. C., Hassan, M. M., Ali, R. A. H., Abugabal, Y. I., Girard, L. M., Li, D., Chang, P., Raghav, K. P. S., Morris, J., Wolff, R. A., Rashid, A., Amin, H. & Kaseb, A., Dec 1 2018, In : Oncotarget. 9, 102, p. 37721-37732 12 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Angiopoietin-1
Hepatocellular Carcinoma
Survival
Confidence Intervals
20 Citations (Scopus)

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Klein, A. P., Wolpin, B. M., Risch, H. A., Stolzenberg-Solomon, R. Z., Mocci, E., Zhang, M., Canzian, F., Childs, E. J., Hoskins, J. W., Jermusyk, A., Zhong, J., Chen, F., Albanes, D., Andreotti, G., Arslan, A. A., Babic, A., Bamlet, W. R., Beane-Freeman, L., Berndt, S. I., Blackford, A. & 103 others, Borges, M., Borgida, A., Bracci, P. M., Brais, L., Brennan, P., Brenner, H., Bueno-De-Mesquita, B., Buring, J., Campa, D., Capurso, G., Cavestro, G. M., Chaffee, K. G., Chung, C. C., Cleary, S., Cotterchio, M., Dijk, F., Duell, E. J., Foretova, L., Fuchs, C., Funel, N., Gallinger, S., Gaziano, J. M. M., Gazouli, M., Giles, G. G., Giovannucci, E., Goggins, M., Goodman, G. E., Goodman, P. J., Hackert, T., Haiman, C., Hartge, P., Hasan, M., Hegyi, P., Helzlsouer, K. J., Herman, J., Holcatova, I., Holly, E. A., Hoover, R., Hung, R. J., Jacobs, E. J., Jamroziak, K., Janout, V., Kaaks, R., Khaw, K. T., Klein, E. A., Kogevinas, M., Kooperberg, C., Kulke, M. H., Kupcinskas, J., Kurtz, R. J., Laheru, D., Landi, S., Lawlor, R. T., Lee, I. M., Lemarchand, L., Lu, L., Malats, N., Mambrini, A., Mannisto, S., Milne, R. L., Mohelníková-Duchoňová, B., Neale, R. E., Neoptolemos, J. P., Oberg, A. L., Olson, S. H., Orlow, I., Pasquali, C., Patel, A. V., Peters, U., Pezzilli, R., Porta, M., Real, F. X., Rothman, N., Scelo, G., Sesso, H. D., Severi, G., Shu, X. O., Silverman, D., Smith, J. P., Soucek, P., Sund, M., Talar-Wojnarowska, R., Tavano, F., Thornquist, M. D., Tobias, G. S., Van Den Eeden, S. K., Vashist, Y., Visvanathan, K., Vodicka, P., Wactawski-Wende, J., Wang, Z., Wentzensen, N., White, E., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Zheng, W., Kraft, P., Li, D., Chanock, S., Obazee, O., Petersen, G. M. & Amundadottir, L. T., Dec 1 2018, In : Nature communications. 9, 1, 556.

Research output: Contribution to journalArticle

genome
loci
Pancreatic Neoplasms
Meta-Analysis
Genes
4 Citations (Scopus)

Pancreatic cancer risk is modulated by inflammatory potential of diet and ABO genotype: A consortia-based evaluation and replication study

Antwi, S. O., Bamlet, W. R., Pedersen, K. S., Chaffee, K. G., Risch, H. A., Shivappa, N., Steck, S. E., Anderson, K. E., Bracci, P. M., Polesel, J., Serraino, D., La Vecchia, C., Bosetti, C., Li, D., Oberg, A. L., Arslan, A. A., Albanes, D., Duell, E. J., Huybrechts, I., Amundadottir, L. T. & 16 others, Hoover, R., Mannisto, S., Chanock, S. J., Zheng, W., Shu, X. O., Stepien, M., Canzian, F., Bueno-De-Mesquita, B., Quirós, J. R., Zeleniuch-Jacquotte, A., Bruinsma, F., Milne, R. L., Giles, G. G., Hébert, J. R., Stolzenberg-Solomon, R. Z. & Petersen, G. M., Jul 30 2018, In : Carcinogenesis. 39, 8, p. 1056-1067 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Genotype
Diet
Confidence Intervals
Case-Control Studies
7 Citations (Scopus)

Plectin-1 Targeted Dual-modality Nanoparticles for Pancreatic Cancer Imaging

Chen, X., Zhou, H., Li, X., Duan, N., Hu, S., Liu, Y., Yue, Y., Song, L., Zhang, Y., Li, D. & Wang, Z., Apr 2018, In : EBioMedicine. 30, p. 129-137 9 p.

Research output: Contribution to journalArticle

Plectin
Pancreatic Neoplasms
Nanoparticles
Imaging techniques
Magnetic resonance

The Association of Recently Diagnosed Diabetes and Long-term Diabetes with Survival in Pancreatic Cancer Patients: A Pooled Analysis

Jeon, C. Y., Li, D., Cleary, S., Stolzenberg-Solomon, R., Bosetti, C., La Vecchia, C., Porta, M., Toriola, A. T., Hung, R. J., Kurtz, R. C. & Olson, S. H., Mar 1 2018, In : Pancreas. 47, 3, p. 314-320 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Adenocarcinoma
Survival
Confidence Intervals
Mortality
5 Citations (Scopus)

Thiazolidinedione therapy and breast cancer risk in diabetic women: A systematic review and meta-analysis

Du, R., Lin, L., Cheng, D., Xu, Y., Xu, M., Chen, Y., Wang, W., Bi, Y., Li, D. & Lu, J., Feb 1 2018, In : Diabetes/Metabolism Research and Reviews. 34, 2, e2961.

Research output: Contribution to journalReview article

Thiazolidinediones
Meta-Analysis
Breast Neoplasms
Odds Ratio
Confidence Intervals
2017
7 Citations (Scopus)

Age at menarche is associated with the prevalence of non-alcoholic fatty liver disease later in life:

Lu, J., Zhang, J., Du, R., Wang, T., Xu, M., Xu, Y., Wang, W., Bi, Y., Li, D., Chen, Y. & Ning, G., Jan 1 2017, In : Journal of Diabetes. 9, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

Menarche
Insulin Resistance
Body Mass Index
Homeostasis
Obesity
123 Citations (Scopus)

Association between telomere length and risk of cancer and non-neoplastic diseases a mendelian randomization study

Telomeres Mendelian Randomization Collaboration, Jan 1 2017, In : JAMA Oncology. 3, 5, p. 636-651 16 p.

Research output: Contribution to journalArticle

Telomere
Random Allocation
Odds Ratio
Confidence Intervals
Neoplasms
1 Citation (Scopus)

A tumor vessel-targeting fusion protein elicits a chemotherapeutic bystander effect in pancreatic ductal adenocarcinoma

Chen, C. T., Chen, Y. C., Du, Y., Han, Z., Ying, H., Bouchard, R. R., Hsu, J. L., Hsu, J. M., Mitcham, T. M., Chen, M. K., Sun, H. L., Chang, S. S., Li, D., Chang, P., DePinho, R. A. & Hung, M. C., Jan 1 2017, In : American Journal of Cancer Research. 7, 3, p. 657-672 16 p.

Research output: Contribution to journalArticle

Bystander Effect
Protein Transport
Adenocarcinoma
Flucytosine
Neoplasms
49 Citations (Scopus)

Diabetes, pancreatogenic diabetes, and pancreatic cancer

Andersen, D. K., Korc, M., Petersen, G. M., Eibl, G., Li, D., Rickels, M. R., Chari, S. T. & Abbruzzese, J. L., May 1 2017, In : Diabetes. 66, 5, p. 1103-1110 8 p.

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Adenocarcinoma
Type 2 Diabetes Mellitus
Early Diagnosis
Research
3 Citations (Scopus)

Dietary acrylamide and the risk of pancreatic cancer in the International Pancreatic Cancer Case-Control Consortium (PanC4)

Pelucchi, C., Rosato, V., Bracci, P. M., Li, D., Neale, R. E., Lucenteforte, E., Serraino, D., Anderson, K. E., Fontham, E., Holly, E. A., Hassan, M. M., Polesel, J., Bosetti, C., Strayer, L., Su, J., Boffetta, P., Duell, E. J. & La Vecchia, C., Jan 1 2017, In : Annals of Oncology. 28, 2, p. 408-414 7 p.

Research output: Contribution to journalArticle

Acrylamide
Pancreatic Neoplasms
Confidence Intervals
Odds Ratio
Logistic Models
13 Citations (Scopus)

Downregulation of human endogenous retrovirus type K (HERV-K) viral env RNA in pancreatic cancer cells decreases cell proliferation and tumor growth

Li, M., Radvanyi, L., Yin, B., Li, J., Chivukula, R., Lin, K., Lu, Y., Shen, J. J., Chang, D. Z., Li, D., Johanning, G. L. & Wang-Johanning, F., Oct 1 2017, In : Clinical Cancer Research. 23, 19, p. 5892-5911 20 p.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Viral RNA
Pancreatic Neoplasms
Down-Regulation
Cell Proliferation
12 Citations (Scopus)

Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers

Luo, Z., Li, Y., Zuo, M., Liu, C., Yan, D., Wang, H. & Li, D., May 2017, In : Molecular Carcinogenesis. 56, 5, p. 1438-1448 11 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Neoplastic Stem Cells
Pancreatic Neoplasms
Neoplasms
Staining and Labeling
17 Citations (Scopus)

Estrogen Replacement Reduces Risk and Increases Survival Times of Women With Hepatocellular Carcinoma

Hassan, M. M., Botrus, G., Abdel-Wahab, R., Wolff, R. A., Li, D., Tweardy, D., Phan, A. T., Hawk, E., Javle, M., Lee, J. S., Torres, H. A., Rashid, A., Lenzi, R., Hassabo, H. M., Abaza, Y., Shalaby, A. S., Lacin, S., Morris, J., Patt, Y. Z., Amos, C. I. & 4 others, Khaderi, S. A., Goss, J. A., Jalal, P. K. & Kaseb, A. O., Nov 2017, In : Clinical Gastroenterology and Hepatology. 15, 11, p. 1791-1799 9 p.

Research output: Contribution to journalArticle

Estrogen Replacement Therapy
Hepatocellular Carcinoma
Survival
Menopause
Estrogens
12 Citations (Scopus)

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Fang, J., Jia, J., Makowski, M., Xu, M., Wang, Z., Zhang, T., Hoskins, J. W., Choi, J., Han, Y., Zhang, M., Thomas, J., Kovacs, M., Collins, I., Dzyadyk, M., Thompson, A., O'Neill, M., Das, S., Lan, Q., Koster, R., Stolzenberg-Solomon, R. S. & 215 others, Kraft, P., Wolpin, B. M., Jansen, P. W. T. C., Olson, S., McGlynn, K. A., Kanetsky, P. A., Chatterjee, N., Barrett, J. H., Dunning, A. M., Taylor, J. C., Newton-Bishop, J. A., Timothy Bishop, D., Andresson, T., Petersen, G. M., Amos, C. I., Iles, M. M., Nathanson, K. L., Landi, M. T., Vermeulen, M., Brown, K. M., Amundadottir, L. T., Canzian, F., Kooperberg, C., Arslan, A. A., Bracci, P. M., Buring, J., Duell, E. J., Gallinger, S., Jacobs, E. J., Kamineni, A., Van Den Eeden, S., Klein, A. P., Kolonel, L. N., Li, D., Olson, S. H., Risch, H. A., Sesso, H. D., Visvanathan, K., Zheng, W., Albanes, D., Austin, M. A., Boutron-Ruault, M. C., Bueno-De-Mesquita, H. B., Cotterchio, M., Gaziano, J. M., Giovannucci, E. L., Goggins, M., Gross, M., Hassan, M., Helzlsouer, K. J., Holly, E. A., Hunter, D. J., Jenab, M., Kaaks, R., Key, T. J., Khaw, K. T., Krogh, V., Kurtz, R. C., LaCroix, A., Le Marchand, L., Mannisto, S., Patel, A. V., Peeters, P. H. M., Riboli, E., Shu, X. O., Sund, M., Thornquist, M., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Wactawski-Wende, J., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Hoover, R., Hartge, P., Fuchs, C., Chanock, S. J., Stevens, V., Albanes, D., Caporaso, N. E., Brennan, P., McKay, J., Wu, X., Hung, R. J., McLaughlin, J. R., Bickeboller, H., Risch, A., Wichmann, E., Houlston, R. S., Mann, G., Hopper, J., Aitken, J., Armstrong, B., Giles, G., Holland, E., Kefford, R., Cust, A., Jenkins, M., Schmid, H., Puig, S., Aguilera, P., Badenas, C., Barreiro, A., Carrera, C., Gabriel, D., Xavier, P. G., Iglesias-Garcia, P., Malvehy, J., Mila, M., Pigem, R., Potrony, M., Puig Butille, J. A., Tell-Marti, G., Hayward, N. K., Martin, N. G., Montgomery, G., Duffy, D. L., Whiteman, D. C., MacGregor, S., Calista, D., Landi, G., Minghetti, P., Arcangeli, F., Bertazzi, P. A., Ghiorzo, P., Bianchi-Scarra, G., Pastorino, L., Bruno, W., Andreotti, V., Queirolo, P., Spagnolo, F., MacKie, R., Lang, J., Gruis, N., Van Nieuwpoort, F. A., Out, C., Bergman, W., Kukutsch, N., Bavinck, J. N. B., Bakker, B., Van Der Stoep, N., Ter Huurne, J., Van Der Rhee, H., Bekkenk, M., Snels, D., Van Praag, M., Brochez, L., Gerritsen, R., Crijns, M., Vasen, H., Janssen, B., Ingvar, C., Olsson, H., Jönsson, G., Borg, Å., Harbst, K., Nielsen, K., Zander, A. S., Molven, A., Helsing, P., Andresen, P. A., Rootwelt, H., Akslen, L. A., Paillerets, B. B. D., Demenais, F., Avril, M. F., Chaudru, V., Jeannin, P., Lesueur, F., Maubec, E., Mohamdi, H., Bossard, M., Vaysse, A., Boitier, F., Caron, O., Caux, F., Dalle, S., Dereure, O., Leroux, D., Martin, L., Mateus, C., Robert, C., Stoppa-Lyonnet, D., Thomas, L., Wierzbicka, E., Elder, D. E., Ming, M., Mitra, N., Debniak, T., Lubinski, J., Hocevar, M., Novakovic, S., Peric, B., Skerl, P., Hansson, J., Höiom, V., Friedman, E., Azizi, E., Baron-Epel, O., Scope, A., Pavlotsky, F., Cohen-Manheim, I., Laitman, Y., Harland, M., Randerson-Moor, J., Laye, J., Davies, J., Nsengimana, J., O'Shea, S., Chan, M., Gascoyne, J., Tucker, M. A., Goldstein, A. M. & Yang, X. R., Jan 1 2017, In : Nature communications. 8, 15034.

Research output: Contribution to journalArticle

Zinc Fingers
loci
Zinc
zinc
cancer
4 Citations (Scopus)

Genetic polymorphisms associated with pancreatic cancer survival: a genome-wide association study

Tang, H. W., Wei, P., Chang, P., Li, Y., Yan, D., Liu, C., Hassan, M. M. & Li, D., Aug 15 2017, In : International Journal of Cancer. 141, 4, p. 678-686 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genetic Polymorphisms
Pancreatic Neoplasms
Single Nucleotide Polymorphism
Survival
2 Citations (Scopus)

Glycemic status and chronic kidney disease in Chinese adults: Findings from the REACTION study

on behalf of the REACTION Study Group, Sep 2017, In : Journal of Diabetes. 9, 9, p. 837-845 9 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Prediabetic State
Odds Ratio
Confidence Intervals
Glucose
98 Citations (Scopus)

High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients

Allenson, K., Castillo, J., San Lucas, F. A., Scelo, G., Kim, D. U., Bernard, V., Davis, G., Kumar, T., Katz, M., Overman, M. J., Foretova, L., Fabianova, E., Holcatova, I., Janout, V., Meric-Bernstam, F., Gascoyne, P., Wistuba, I., Varadhachary, G., Brennan, P., Hanash, S. & 3 others, Li, D., Maitra, A. & Alvarez, H., Apr 1 2017, In : Annals of Oncology. 28, 4, p. 741-747 7 p., mdx004.

Research output: Contribution to journalArticle

Exosomes
Pancreatic Neoplasms
DNA
Adenocarcinoma
Biopsy
20 Citations (Scopus)

RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer

Mao, Y., Shen, J., Lu, Y., Lin, K., Wang, H., Li, Y., Chang, P., Walker, M. G. & Li, D., Jan 1 2017, In : Oncotarget. 8, 26, p. 42537-42547 11 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Pancreatic Neoplasms
Adenocarcinoma
Genes
Transendothelial and Transepithelial Migration
4 Citations (Scopus)

Serum CA 19-9 and risk of incident diabetes in middle-aged and elderly Chinese: a prospective cohort study

Du, R., Sun, W., Lin, L., Sun, J., Peng, K., Xu, Y., Xu, M., Chen, Y., Bi, Y., Wang, W., Li, D. & Lu, J., Feb 1 2017, In : Acta Diabetologica. 54, 2, p. 201-208 8 p.

Research output: Contribution to journalArticle

Cohort Studies
Carbohydrates
Prospective Studies
Antigens
Odds Ratio
2016
6 Citations (Scopus)

Association between the change in body mass index from early adulthood to midlife and subsequent type 2 diabetes mellitus

Sun, W., Shi, L., Ye, Z., Mu, Y., Liu, C., Zhao, J., Chen, L., Li, Q., Yang, T., Yan, L., Wan, Q., Wu, S., Liu, Y., Wang, G., Luo, Z., Tang, X., Chen, G., Huo, Y., Gao, Z., Su, Q. & 20 others, Wang, Y., Qin, G., Deng, H., Yu, X., Shen, F., Chen, L., Zhao, L., Sun, J., Ding, L., Xu, Y., Xu, M., Dai, M., Wang, T., Zhang, D., Lu, J., Bi, Y., Lai, S., Li, D., Wang, W. & Ning, G., Mar 1 2016, In : Obesity. 24, 3, p. 703-709 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Body Mass Index
Confidence Intervals
Odds Ratio
Weight Loss
9 Citations (Scopus)

Association of insulin resistance with breast, ovarian, endometrial and cervical cancers in non-diabetic women

Sun, W., Lu, J., Wu, S., Bi, Y., Mu, Y., Zhao, J., Liu, C., Chen, L., Shi, L., Li, Q., Yang, T., Yan, L., Wan, Q., Liu, Y., Wang, G., Luo, Z., Tang, X., Chen, G., Huo, Y., Gao, Z. & 21 others, Su, Q., Ye, Z., Wang, Y., Qin, G., Deng, H., Yu, X., Shen, F., Chen, L., Zhao, L., Wang, T., Sun, J., Xu, M., Xu, Y., Chen, Y., Dai, M., Zhang, J., Zhang, D., Lai, S., Li, D., Ning, G. & Wang, W., Jan 1 2016, In : American Journal of Cancer Research. 6, 10, p. 2334-2344 11 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Uterine Cervical Neoplasms
Ovarian Neoplasms
Insulin Resistance
Breast Neoplasms
23 Citations (Scopus)

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

MacHiela, M. J., Zhou, W., Karlins, E., Sampson, J. N., Freedman, N. D., Yang, Q., Hicks, B., Dagnall, C., Hautman, C., Jacobs, K. B., Abnet, C. C., Aldrich, M. C., Amos, C., Amundadottir, L. T., Arslan, A. A., Beane-Freeman, L. E., Berndt, S. I., Black, A., Blot, W. J., Bock, C. H. & 156 others, Bracci, P. M., Brinton, L. A., Bueno-De-Mesquita, H. B., Burdett, L., Buring, J. E., Butler, M. A., Canzian, F., Carreón, T., Chaffee, K. G., Chang, I. S., Chatterjee, N., Chen, C., Chen, C., Chen, K., Chung, C. C., Cook, L. S., Crous Bou, M., Cullen, M., Davis, F. G., De Vivo, I., Ding, T., Doherty, J., Duell, E. J., Epstein, C. G., Fan, J. H., Figueroa, J. D., Fraumeni, J. F., Friedenreich, C. M., Fuchs, C. S., Gallinger, S., Gao, Y. T., Gapstur, S. M., Garcia-Closas, M., Gaudet, M. M., Gaziano, J. M., Giles, G. G., Gillanders, E. M., Giovannucci, E. L., Goldin, L., Goldstein, A. M., Haiman, C. A., Hallmans, G., Hankinson, S. E., Harris, C. C., Henriksson, R., Holly, E. A., Hong, Y. C., Hoover, R. N., Hsiung, C. A., Hu, N., Hu, W., Hunter, D. J., Hutchinson, A., Jenab, M., Johansen, C., Khaw, K. T., Kim, H. N., Kim, Y. H., Kim, Y. T., Klein, A. P., Klein, R., Koh, W. P., Kolonel, L. N., Kooperberg, C., Kraft, P., Krogh, V., Kurtz, R. C., Lacroix, A., Lan, Q., Landi, M. T., Marchand, L. L., Li, D., Liang, X., Liao, L. M., Lin, D., Liu, J., Lissowska, J., Lu, L., Magliocco, A. M., Malats, N., Matsuo, K., McNeill, L. H., McWilliams, R. R., Melin, B. S., Mirabello, L., Moore, L., Olson, S. H., Orlow, I., Park, J. Y., Patinõ-Garcia, A., Peplonska, B., Peters, U., Petersen, G. M., Pooler, L., Prescott, J., Prokunina-Olsson, L., Purdue, M. P., Qiao, Y. L., Rajaraman, P., Real, F. X., Riboli, E., Risch, H. A., Rodriguez-Santiago, B., Ruder, A. M., Savage, S. A., Schumacher, F., Schwartz, A. G., Schwartz, K. L., Seow, A., Wendy Setiawan, V., Severi, G., Shen, H., Sheng, X., Shin, M. H., Shu, X. O., Silverman, D. T., Spitz, M. R., Stevens, V. L., Stolzenberg-Solomon, R., Stram, D., Tang, Z. Z., Taylor, P. R., Teras, L. R., Tobias, G. S., Van Den Berg, D., Visvanathan, K., Wacholder, S., Wang, J. C., Wang, Z., Wentzensen, N., Wheeler, W., White, E., Wiencke, J. K., Wolpin, B. M., Wong, M. P., Wu, C., Wu, T., Wu, X., Wu, Y. L., Wunder, J. S., Xia, L., Yang, H. P., Yang, P. C., Yu, K., Zanetti, K. A., Zeleniuch-Jacquotte, A., Zheng, W., Zhou, B., Ziegler, R. G., Perez-Jurado, L. A., Caporaso, N. E., Rothman, N., Tucker, M., Dean, M. C., Yeager, M. & Chanock, S. J., Jun 13 2016, In : Nature communications. 7, 11843.

Research output: Contribution to journalArticle

Mosaicism
chromosomes
X Chromosome
Chromosomes
Sex Chromosomes
2 Citations (Scopus)
gemcitabine
Drug Resistance
DNA Repair
DNA Damage
Drug Therapy
5 Citations (Scopus)

Menstrual and Reproductive Factors, Hormone Use, and Risk of Pancreatic Cancer: Analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)

Lujan-Barroso, L., Zhang, W., Olson, S. H., Gao, Y. T., Yu, H., Baghurst, P. A., Bracci, P. M., Bueno-De-Mesquita, H. B., Foretová, L., Gallinger, S., Holcatova, I., Janout, V., Ji, B. T., Kurtz, R. C., La Vecchia, C., Lagiou, P., Li, D., Miller, A. B., Serraino, D., Zatonski, W. & 2 others, Risch, H. A. & Duell, E. J., Nov 1 2016, In : Pancreas. 45, 10, p. 1401-1410 10 p.

Research output: Contribution to journalArticle

Hysterectomy
Pancreatic Neoplasms
Hormones
Hormone Replacement Therapy
Confidence Intervals
78 Citations (Scopus)

Minimally invasive genomic and transcriptomic profiling of visceral cancers by next-generation sequencing of circulating exosomes

San Lucas, F. A., Allenson, K., Bernard, V., Castillo, J., Kim, D. U., Ellis, K., Ehli, E. A., Davies, G. E., Petersen, J. L., Li, D., Wolff, R., Katz, M., Varadhachary, G., Wistuba, I., Maitra, A. & Alvarez, H., Apr 1 2016, In : Annals of Oncology. 27, 4, p. 635-641 7 p.

Research output: Contribution to journalArticle

Exosomes
Gene Fusion
Neoplasms
Exome
Biopsy
2 Citations (Scopus)

RECQ1 A159C Polymorphism Is Associated with Overall Survival of Patients with Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704

Li, D., Moughan, J., Crane, C., Hoffman, J. P., Regine, W. F., Abrams, R. A., Safran, H., Liu, C., Chang, P., Freedman, G. M., Winter, K. A., Guha, C. & Abbruzzese, J. L., Jan 1 2016, In : International Journal of Radiation Oncology Biology Physics. 94, 3, p. 554-560 7 p.

Research output: Contribution to journalArticle

Radiation Oncology
polymorphism
Pancreatic Neoplasms
radiation therapy
Radiotherapy
7 Citations (Scopus)
Cardiovascular Diseases
Kidney
Glomerular Filtration Rate
Coronary Disease
Chronic Renal Insufficiency
18 Citations (Scopus)

Risk Factors for Early-Onset and Very-Early-Onset Pancreatic Adenocarcinoma: A Pancreatic Cancer Case-Control Consortium (PanC4) Analysis

McWilliams, R. R., Maisonneuve, P., Bamlet, W. R., Petersen, G. M., Li, D., Risch, H. A., Yu, H., Fontham, E. T. H., Luckett, B., Bosetti, C., Negri, E., La Vecchia, C., Talamini, R., De Mesquita, H. B. B., Bracci, P., Gallinger, S., Neale, R. E. & Lowenfels, A. B., Feb 1 2016, In : Pancreas. 45, 2, p. 311-316 6 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Adenocarcinoma
Alcohols
Obesity
Smoking
2 Citations (Scopus)

RNA sequencing-based analysis of gallbladder cancer reveals the importance of the liver X receptor and lipid metabolism in gallbladder cancer

Zuo, M., Rashid, A., Wang, Y., Jain, A., Li, D., Behari, A., Kapoor, V. K., Koay, E. J., Chang, P., Vauthey, J. N., Li, Y., Espinoza, J. A., Roa, J. C. & Javle, M., Jun 7 2016, In : Oncotarget. 7, 23, p. 35302-35312 11 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Gallbladder Neoplasms
Lipid Metabolism
Retinoid X Receptors
Genes
32 Citations (Scopus)

Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer

Liu, C., Eng, C., Shen, J., Lu, Y., Yoko, T., Mehdizadeh, A., Chang, G. J., Rodriguez-Bigas, M. A., Li, Y., Chang, P., Mao, Y., Hassan, M. M., Wang, F. & Li, D., Jan 1 2016, In : Oncotarget. 7, 46, p. 76250-76260 11 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Recurrence
Serum
MicroRNAs
Neoplasms
4 Citations (Scopus)

Survivin-targeted nanoparticles for pancreatic tumor imaging in mouse model

Wang, Z., Tong, M., Chen, X., Hu, S., Yang, Z., Zhang, Y., Zhou, H., Wu, Y., Li, X. & Li, D., Aug 1 2016, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 12, 6, p. 1651-1661 11 p.

Research output: Contribution to journalArticle

Nanoparticles
Tumors
Imaging techniques
Oligonucleotides
Neoplasms
26 Citations (Scopus)

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21

Zhang, M., Wang, Z., Obazee, O., Jia, J., Childs, E. J., Hoskins, J., Figlioli, G., Mocci, E., Collins, I., Chung, C. C., Hautman, C., Arslan, A. A., Beane-Freeman, L., Bracci, P. M., Buring, J., Duell, E. J., Gallinger, S., Giles, G. G., Goodman, G. E., Goodman, P. J. & 103 others, Kamineni, A., Kolonel, L. N., Kulke, M. H., Malats, N., Olson, S. H., Sesso, H. D., Visvanathan, K., White, E., Zheng, W., Abnet, C. C., Albanes, D., Andreotti, G., Brais, L., Bas Bueno-de-Mesquita, H., Basso, D., Berndt, S. I., Boutron-Ruault, M. C., Bijlsma, M. F., Brenner, H., Burdette, L., Campa, D., Caporaso, N. E., Capurso, G., Cavestro, G. M., Cotterchio, M., Costello, E., Elena, J., Boggi, U., Michael Gaziano, J., Gazouli, M., Giovannucci, E. L., Goggins, M., Gross, M., Haiman, C. A., Hassan, M., Helzlsouer, K. J., Hu, N., Hunter, D. J., Iskierka-Jazdzewska, E., Jenab, M., Kaaks, R., Key, T. J., Khaw, K. T., Klein, E. A., Kogevinas, M., Krogh, V., Kupcinskas, J., Kurtz, R. C., Landi, M. T., Landi, S., Marchand, L. L., Mambrini, A., Mannisto, S., Milne, R. L., Neale, R. E., Oberg, A. L., Panico, S., Patel, A. V., Peeters, P. H. M., Peters, U., Pezzilli, R., Porta, M., Purdue, M., Ramón Quiros, J., Riboli, E., Rothman, N., Scarpa, A., Scelo, G., Shu, X. O., Silverman, D. T., Soucek, P., Strobel, O., Sund, M., Malecka-Panas, E., Taylor, P. R., Tavano, F., Travis, R. C., Thornquist, M., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Vashist, Y., Vodicka, P., Wactawski-Wende, J., Wentzensen, N., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Kooperberg, C., Risch, H. A., Jacobs, E. J., Li, D., Fuchs, C., Hoover, R., Hartge, P., Chanock, S. J., Petersen, G. M., Stolzenberg-Solomon, R. S., Wolpin, B. M., Kraft, P., Klein, A. P., Canzian, F. & Amundadottir, L. T., Jan 1 2016, In : Oncotarget. 7, 41, p. 66328-66343 16 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Chromosomes
Genome-Wide Association Study
Odds Ratio
Single Nucleotide Polymorphism
27 Citations (Scopus)

Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data

MGS (Molecular Genetics of Schizophrenia) GWAS Consortium, GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium), The GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium, PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium, PanScan Consortium & The GAME-ON/ELLIPSE Consortium, Dec 2016, In : PLoS genetics. 12, 12, e1006493.

Research output: Contribution to journalArticle

Genome-Wide Association Study
genome
single nucleotide polymorphism
Single Nucleotide Polymorphism
polymorphism
2015
3 Citations (Scopus)

193nm lithography fabricated high sensitivity photonic crystal microcavity biosensors for plasma protein detection in patients with pancreatic cancer

Yang, C. J., Tang, N., Yan, H., Chakravarty, S., Li, D. & Chen, R. T., May 4 2015, CLEO: Science and Innovations, CLEO-SI 2015. Optical Society of America (OSA), 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microcavities
biomarkers
Photolithography
photolithography
Tumor Biomarkers

193nm Lithography fabricated high sensitivity photonic crystal microcavity biosensors for plasma protein detection in patients with pancreatic cancer

Yang, C. J., Tang, N., Yan, H., Chakravarty, S., Li, D. & Chen, R. T., Aug 10 2015, 2015 Conference on Lasers and Electro-Optics, CLEO 2015. Institute of Electrical and Electronics Engineers Inc., 7184262. (Conference on Lasers and Electro-Optics Europe - Technical Digest; vol. 2015-August).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microcavities
biomarkers
Photolithography
photolithography
Tumor Biomarkers