Einav Nili Gal-Yam

  • 1406 Citations
  • 11 h-Index
20012018
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Research Output 2001 2018

  • 1406 Citations
  • 11 h-Index
  • 20 Article
  • 1 Review article
2018
3 Citations (Scopus)

Evaluation of tolerability and efficacy of incorporating carboplatin in neoadjuvant anthracycline and taxane based therapy in a BRCA1 enriched triple-negative breast cancer cohort

Sella, T., Nili Gal-Yam, E., Levanon, K., Rotenberg, T. S., Gadot, M., Kuchuk, I., Molho, R. B., Itai, A., Modiano, T. M., Gold, R., Kaufman, B. & Shimon, S. P., Aug 1 2018, In : Breast. 40, p. 141-146 6 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Anthracyclines
Carboplatin
Drug Therapy
Therapeutics
4 Citations (Scopus)

mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues

Bossel Ben-Moshe, N., Gilad, S., Perry, G., Benjamin, S., Balint-Lahat, N., Pavlovsky, A., Halperin, S., Markus, B., Yosepovich, A., Barshack, I., Nili Gal-Yam, E., Domany, E., Kaufman, B. & Dadiani, M., May 30 2018, In : BMC genomics. 19, 1, 419.

Research output: Contribution to journalArticle

Gene Expression Profiling
Paraffin
Formaldehyde
Messenger RNA
RNA Sequence Analysis
2016
7 Citations (Scopus)

Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis

Sapoznik, S., Bahar-Shany, K., Brand, H., Pinto, Y., Gabay, O., Glick-Saar, E., Dor, C., Zadok, O., Barshack, I., Zundelevich, A., Nili Gal-Yam, E., Yung, Y., Hourvitz, A., Korach, J., Beiner, M., Jacob, J., Levanon, E. Y., Barak, M., Aviel-Ronen, S. & Levanon, K., Jan 1 2016, In : Neoplasia. 18, 2, p. 90-99 10 p.

Research output: Contribution to journalArticle

Fallopian Tubes
Ovulation
Carcinogenesis
Epithelial Cells
Inflammation
3 Citations (Scopus)

Tumor evolution inferred by patterns of microRNA expression through the course of disease, therapy, and recurrence in breast cancer

Dadiani, M., Ben-Moshe, N. B., Paluch-Shimon, S., Perry, G., Balint, N., Marin, I., Pavlovski, A., Morzaev, D., Kahana-Edwin, S., Yosepovich, A., Gal-Yam, E. N., Berger, R., Barshack, I., Domany, E. & Kaufman, B., Jul 15 2016, In : Clinical Cancer Research. 22, 14, p. 3651-3662 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Breast Neoplasms
Recurrence
Neoplasms
Therapeutics
2013
11 Citations (Scopus)

Chromatin-modifying agents reactivate embryonic renal stem/progenitor genes in human adult kidney epithelial cells but abrogate dedifferentiation and stemness

Omer, D., Harari-Steinberg, O., Buzhor, E., Metsuyanim, S., Pleniceanu, O., Zundelevich, A., Gal-Yam, E. N. & Dekel, B., Aug 1 2013, In : Cellular Reprogramming. 15, 4, p. 281-292 12 p.

Research output: Contribution to journalArticle

Cell Dedifferentiation
Chromatin
Epithelial Cells
Valproic Acid
Kidney
2012
123 Citations (Scopus)

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

Landan, G., Cohen, N. M., Mukamel, Z., Bar, A., Molchadsky, A., Brosh, R., Horn-Saban, S., Zalcenstein, D. A., Goldfinger, N., Zundelevich, A., Nili Gal-Yam, E., Rotter, V. & Tanay, A., Nov 1 2012, In : Nature Genetics. 44, 11, p. 1207-1214 8 p.

Research output: Contribution to journalArticle

Epigenomics
Methylation
Stochastic Processes
Histone Code
Population
61 Citations (Scopus)

Epigenetic silencing of the tumor suppressor klotho in human breast cancer

Rubinek, T., Shulman, M., Israeli, S., Bose, S., Avraham, A., Zundelevich, A., Evron, E., Gal-Yam, E. N., Kaufman, B. & Wolf, I., Jun 1 2012, In : Breast Cancer Research and Treatment. 133, 2, p. 649-657 9 p.

Research output: Contribution to journalArticle

Epigenomics
Methylation
Breast Neoplasms
Breast
Neoplasms
2011
92 Citations (Scopus)

Mutant p53 R175H upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells

Kogan-Sakin, I., Tabach, Y., Buganim, Y., Molchadsky, A., Solomon, H., Madar, S., Kamer, I., Stambolsky, P., Shelly, A., Goldfinger, N., Valsesia-Wittmann, S., Puisieux, A., Zundelevich, A., Nili Gal-Yam, E., Avivi, C., Barshack, I., Brait, M., Sidransky, D., Domany, E. & Rotter, V., Feb 1 2011, In : Cell death and differentiation. 18, 2, p. 271-281 11 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Prostate
Up-Regulation
Mutation
Epigenetic Repression
2008
192 Citations (Scopus)

Cancer epigenetics: Modifications, screening, and therapy

Nili Gal-Yam, E., Saito, Y., Egger, G. & Jones, P. A., Feb 28 2008, In : Annual Review of Medicine. 59, p. 267-280 14 p.

Research output: Contribution to journalReview article

Epigenomics
Gene expression
Screening
Cells
Deregulation
6 Citations (Scopus)

Epigenetic regulation and nucleosome positioning in the human TATA-less IL-1α promoter

van Rietschoten, J. G. I., Gal-Yam, E. N., Jeong, S., Cortez, C. C., Verweij, C. L. & Jones, P. A., Jul 11 2008, In : Genes and Immunity. 9, 7, p. 582-590 9 p.

Research output: Contribution to journalArticle

Nucleosomes
Interleukin-1
Epigenomics
Genes
Nucleic Acid Regulatory Sequences
243 Citations (Scopus)

Frequent switching of polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

Gal-Yam, E. N., Egger, G., Iniguez, L., Holster, H., Einarsson, S., Zhang, X., Lin, J. C., Liang, G., Jones, P. A. & Tanay, A., Sep 2 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12979-12984 6 p.

Research output: Contribution to journalArticle

DNA Methylation
Prostatic Neoplasms
Epigenomics
Cell Line
DNA
10 Citations (Scopus)

LAP2ζ binds BAF and suppresses LAP2β-mediated transcriptional repression

Shaklai, S., Somech, R., Nili Gal-Yam, E., Deshet-Unger, N., Moshitch-Moshkovitz, S., Hirschberg, K., Amariglio, N., Simon, A. J. & Rechavi, G., May 21 2008, In : European journal of cell biology. 87, 5, p. 267-278 12 p.

Research output: Contribution to journalArticle

Nuclear Envelope
Gene Silencing
Nuclear Lamina
Nuclear Proteins
Histones
2007
18 Citations (Scopus)

Enhanced expression of the nuclear envelope LAP2 transcriptional repressors in normal and malignant activated lymphocytes

Somech, R., Nili Gal-Yam, E., Shaklai, S., Geller, O., Amariglio, N., Rechavi, G. & Simon, A. J., Jun 1 2007, In : Annals of hematology. 86, 6, p. 393-401 9 p.

Research output: Contribution to journalArticle

Nuclear Lamina
Nuclear Envelope
Nuclear Proteins
Lymphocytes
Hematologic Neoplasms
148 Citations (Scopus)

Role of Nucleosomal Occupancy in the Epigenetic Silencing of the MLH1 CpG Island

Lin, J. C., Jeong, S., Liang, G., Takai, D., Fatemi, M., Tsai, Y. C., Egger, G., Gal-Yam, E. N. & Jones, P. A., Nov 13 2007, In : Cancer cell. 12, 5, p. 432-444 13 p.

Research output: Contribution to journalArticle

CpG Islands
Nucleosomes
Epigenomics
Cytosine
decitabine
2006
46 Citations (Scopus)

Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting

Gal-Yam, E. N., Jeong, S., Tanay, A., Egger, G., Lee, A. S. & Jones, P. A., Oct 10 2006, In : PLoS genetics. 2, 9, p. 1451-1463 13 p.

Research output: Contribution to journalArticle

nucleosomes
Nucleosomes
Endoplasmic Reticulum Stress
Transcription Initiation Site
promoter regions
2005
128 Citations (Scopus)

Footprinting of mammalian promoters: Use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level

Fatemi, M., Pao, M. M., Jeong, S., Nili Gal-Yam, E., Egger, G., Weisenberger, D. J. & Jones, P. A., Dec 27 2005, In : Nucleic Acids Research. 33, 20

Research output: Contribution to journalArticle

Nucleosomes
Methyltransferases
Genetic Promoter Regions
CpG Islands
DNA
137 Citations (Scopus)

The nuclear-envelope protein and transcriptional repressor LAP2β interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation

Somech, R., Shaklai, S., Geller, O., Amariglio, N., Simon, A. J., Rechavi, G. & Gal-Yam, E. N., Sep 1 2005, In : Journal of cell science. 118, 17, p. 4017-4025 9 p.

Research output: Contribution to journalArticle

Nuclear Envelope
Nuclear Proteins
Histones
Histone Deacetylase Inhibitors
Histone Deacetylases
2003
11 Citations (Scopus)

Reduced Human Germ Cell-Less (HGCL) Expression in Azoospermic Men with Severe Germinal Cell Impairment

Kleiman, S. E., Yogev, L., Gal-Yam, E. N., Hauser, R., Gamzu, R., Botchan, A., Paz, G., Yavetz, H., Maymon, B. B. S., Schreiber, L., Barzilai, S., Amariglio, N., Rechavi, G. & Simon, A. J., Jan 1 2003, In : Journal of andrology. 24, 5, p. 670-675 6 p.

Research output: Contribution to journalArticle

Germ Cells
Spermatogenesis
Meiosis
Y Chromosome
Drosophila
2001
161 Citations (Scopus)

Nuclear membrane protein LAP2β mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less)

Nili Gal-Yam, E., Cojocaru, G. S., Kalma, Y., Ginsberg, D., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Berger, R., Shaklai, S., Amariglio, N., Brok-Simoni, F., Simon, A. J. & Rechavi, G., Nov 7 2001, In : Journal of cell science. 114, 18, p. 3297-3307 11 p.

Research output: Contribution to journalArticle

Nuclear Envelope
Nuclear Proteins
Germ Cells
Membrane Proteins
E2F Transcription Factors
2 Citations (Scopus)

The human germ cell-less (HGCL): A candidate gene for Alström syndrome

Nili Gal-Yam, E., Cojocaru, G. S., Collin, G. B., Nishina, P. M., Brok-Simoni, F., Amariglio, N., Simon, A. J. & Rechavi, G., Jan 1 2001, In : Journal of Endocrine Genetics. 2, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Germ Cells
Genes
Eunuchism
Acanthosis Nigricans
Retinitis Pigmentosa

The Human Germ Cell-Less (HGCL): A Candidate Gene for Alström Syndrome

Nili Gal-Yam, E., Cojocaru, G. S., Brok-Simoni, F., Amariglio, N., Simon, A. J., Rechavi, G., Collin, G. B., Nishina, P. M. & Simon, A. J., Jan 1 2001, In : International Journal on Disability and Human Development. 2, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Germ Cells
Genes
Alstrom Syndrome
Gels
Eunuchism