Hector A Alvarez

Assistant Professor

  • 2243 Citations
  • 20 h-Index
20072019
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Pancreatic Neoplasms Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Exosomes Medicine & Life Sciences
Gallbladder Neoplasms Medicine & Life Sciences
Connective Tissue Growth Factor Medicine & Life Sciences
Hedgehogs Medicine & Life Sciences
Therapeutics Medicine & Life Sciences

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Research Output 2007 2019

  • 2243 Citations
  • 20 h-Index
  • 34 Article
7 Citations (Scopus)

Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer

Bernard, V., Kim, D. U., San Lucas, F. A., Castillo Arias, J. A., Allenson, K., Mulu, F. C., Stephens, B. M., Huang, J., Semaan, A., Guerrero, P. A., Kamyabi, N., Zhao, J., Hurd, M. W., Koay, E. J., Taniguchi, C., Herman, J. M., Javle, M., Wolff, R. A., Katz, M. H., Varadhachary, G. R. & 2 othersMaitra, A. & Alvarez, H. A., Jan 1 2019, In : Gastroenterology. 156, 1, p. 108-118.e4

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Nucleic Acids
Exosomes
Circulating Neoplastic Cells
DNA
4 Citations (Scopus)

Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity

Capello, M., Vykoukal, J. V., Katayama, H., Bantis, L. E., Wang, H., Kundnani, D. L., Aguilar-Bonavides, C., Aguilar, M., Tripathi, S. C., Dhillon, D. S., Momin, A. A., Peters, H., Katz, M. H., Alvarez, H. A., Bernard, V., Ferri-Borgogno, S., Brand, R., Adler, D. G., Firpo, M. A., Mulvihill, S. J. & 5 othersMolldrem, J. J., Feng, Z., Taguchi, A., Maitra, A. & Hanash, S., Dec 1 2019, In : Nature communications. 10, 1, 254.

Research output: Contribution to journalArticle

Exosomes
decoys
harbors
antigens
Cytotoxicity
2 Citations (Scopus)

Single-cell transcriptomics of pancreatic cancer precursors demonstrates epithelial and microenvironmental heterogeneity as an early event in neoplastic progression

Bernard, V., Semaan, A., Huang, J., Anthony San Lucas, F., Mulu, F. C., Stephens, B. M., Guerrero, P. A., Huang, Y., Zhao, J., Kamyabi, N., Sen, S., Scheet, P. A., Taniguchi, C., Kim, M., Tzeng, C-W. D., Katz, M. H., Singhi, A. D., Maitra, A. & Alvarez, H. A., Apr 1 2019, In : Clinical Cancer Research. 25, 7, p. 2194-2205 12 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
Neoplasms
Adenocarcinoma
Single-Cell Analysis
RNA Sequence Analysis
6 Citations (Scopus)

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations

Shah, M. Y., Ferracin, M., Pileczki, V., Chen, B., Redis, R., Fabris, L., Zhang, X., Ivan, C., Shimizu, M., Rodriguez-Aguayo, C., Dragomir, M., Van Roosbroeck, K., Almeida, M. I. C. D., Ciccone, M., Nedelcu, D., Cortez, M. A. A., Manshouri, T., Calin, S., Muftuoglu, M., Banerjee, P. P. & 24 othersBadiwi, M. H., Parker-Thornburg, J., Multani, A. S., Welsh, J., Estecio, M. R., Ling, H., Tomuleasa, C., Dima, D., Yang, H., Alvarez, H. A., You, M. J., Radovich, M., Shpall, E., Fabbri, M., Rezvani, K., Girnita, L., Berindan-Neagoe, I., Maitra, A., Verstovsek, S., Fodde, R., Bueso-Ramos, C. E., Gagea Iurascu, M., Garcia-Manero, G. & Calin, G. A., Apr 1 2018, In : Genome Research. 28, 4, p. 432-447 16 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Single Nucleotide Polymorphism
RNA
Mutation
Neoplasms
1 Citation (Scopus)

Dynamic changes during the treatment of pancreatic cancer

Wolff, R. A., Wang-Gillam, A., Alvarez, H. A., Tiriac, H., Engle, D., Hou, S., Groff, A. F., Lucas, A. S., Bernard, V., Allenson, K., Castillo Arias, J. A., Kim, D., Mulu, F., Huang, J., Stephens, B., Wistuba, I. I., Katz, M. H., Varadhachary, G. R., Park, Y. K., Hicks, J. & 10 othersChinnaiyan, A., Scampavia, L., Spicer, T., Gerhardinger, C., Maitra, A., Tuveson, D., Rinn, J., Lizee, G. A., Yee, C. & Levine, A. J., Jan 1 2018, In : Oncotarget. 9, 19, p. 14764-14790 27 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Organoids
Therapeutics
Immunotherapy
Neoplasms