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Dive into the research topics where Helen Piwnica-Worms is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Regulation of mitochondrial ROS by C15ORF48 in a basal cell subpopulation contributes to chemotherapy resistance in TNBC
Jiang, Y., Abdulkareem, N. M., Rinkenbaugh, A. L., Qi, Y., Wall, S. W., Zhang, X., Shao, J., Jeter-Jones, S., Cai, S., Hancock, F. B., Echeverria, G. V., Chang, J. T. & Piwnica-Worms, H., Apr 3 2026, In: Science Advances. 12, 14, p. eaec8684Research output: Contribution to journal › Article › peer-review
Open Access -
Resistance to neoadjuvant talazoparib in triple-negative breast cancer by BRN2-induced ATR/STAT3 pathways or SHLD2 subclone expansion
Abdulkareem, N. M., Jiang, Y., Qi, Y., Liu, X., Zhang, X., Cai, S., Shao, J., Jeter-Jones, S., Rinkenbaugh, A. L., Cheng, C. C., Hancock, F., Schwartz, J., Litton, J. K., Chang, J. T. & Piwnica-Worms, H., Apr 21 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 16, e2513742123.Research output: Contribution to journal › Article › peer-review
Open Access -
An Annotated Biobank of Triple-Negative Breast Cancer Patient-Derived Xenografts Features Treatment-Naïve and Longitudinal Samples during Neoadjuvant Chemotherapy
Rinkenbaugh, A. L., Qi, Y., Cai, S., Shao, J., Baameur Hancock, F., Jeter-Jones, S. L., Zhang, X., Powell, E., Huo, L., Lau, R., Fu, C., Gould, R., den Hollander, P., Ravenberg, E. E., White, J. B., Rauch, G. M., Arun, B., Yam, C., Thompson, A. M. & Echeverria, G. V. & 4 others, , Nov 3 2025, In: Cancer Research. 85, 21, p. 4062-4080 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
FGFR3-induced Y158 PARP1 phosphorylation promotes PARP inhibitor resistance via BRG1/MRE11-mediated DNA repair in breast cancer models
Chen, M. K., Yamaguchi, H., Gao, Y., Xia, W., Chang, J. T., Hsiao, Y. C., Shegute, T. W., Lin, Z. S., Wu, C. S., Wang, Y. H., Litton, J. K., Ding, Q., Wei, Y., Chu, Y. Y., Meric-Bernstam, F., Piwnica-Worms, H., Arun, B., Ahnert, J. R., Liu, J. & Yao, J. & 12 others, , Jul 15 2025, In: Journal of Clinical Investigation. 135, 14, e173757.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations -
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers
Lei, G., Mao, C., Horbath, A. D., Yan, Y., Cai, S., Yao, J., Jiang, Y., Sun, M., Liu, X., Cheng, J., Xu, Z., Lee, H., Li, Q., Lu, Z., Zhuang, L., Chen, M. K., Alapati, A., Yap, T. A., Hung, M. C. & You, M. J. & 2 others, , Aug 1 2024, In: Cancer discovery. 14, 8, p. 1476-1495 20 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Link opens in a new tab Scopus citations