• 15100 Citations
  • 75 h-Index
1973 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1973 2019

1992
79 Citations (Scopus)
Trans-Activators
DNA
RNA Polymerase I
Peptide Initiation Factors
Proteins
32 Citations (Scopus)

Limited proteolysis unmasks specific DNA-binding of the murine RNA polymerase I-specific transcription termination factor TTFI

Smid, A., Finsterer, M. & Grummt, I., Oct 5 1992, In : Journal of Molecular Biology. 227, 3, p. 635-647 13 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Proteolysis
Transcription Factors
DNA
Ribosomal DNA
153 Citations (Scopus)

The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation

Voit, R., Schnapp, A., Kuhn, A., Rosenbauer, H., Hirschmann, P., Stunnenberg, H. G. & Grummt, I., Jan 1 1992, In : EMBO Journal. 11, 6, p. 2211-2218 8 p.

Research output: Contribution to journalArticle

Casein Kinase II
Phosphorylation
Transcription
Transcriptional Activation
Tail
1991
4 Citations (Scopus)

Isolation of multiple protein factors involved in ribosomal DNA transcription

Heilgenthal, G. & Grummt, I., Nov 29 1991, In : Journal of Chromatography A. 587, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Transcription
Ribosomal DNA
RNA Polymerase I
Proteins
Genes
23 Citations (Scopus)

Trans-acting factors involved in species-specificity and control of mouse ribosomal gene transcription

Schnapp, A., Rosenbauer, H. & Grummt, I., May 1 1991, In : Molecular and Cellular Biochemistry. 104, 1-2, p. 137-147 11 p.

Research output: Contribution to journalArticle

Species Specificity
Trans-Activators
Transcription
Ribosomal DNA
RNA Polymerase I
97 Citations (Scopus)
Pol1 Transcription Initiation Complex Proteins
Transcription
Ribosomal DNA
DNA Polymerase I
Intercellular Signaling Peptides and Proteins
1990
54 Citations (Scopus)
Open Access
RNA Polymerase I
Cell-Free System
Nucleic Acid Repetitive Sequences
Ribosomal DNA
rRNA Genes
88 Citations (Scopus)

A growth-dependent transcription initiation factor (TIF-IA) interacting with RNA polymerase I regulates mouse ribosomal RNA synthesis

Schnapp, A., Pfleiderer, C., Rosenbauer, H. & Grummt, I., Sep 7 1990, In : EMBO Journal. 9, 9, p. 2857-2863 7 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Peptide Initiation Factors
Ribosomal RNA
Transcription
Ribosomal DNA
29 Citations (Scopus)

An undecamer DNA sequence directs termination of human ribosomal gene transcription

Pfleiderer, C., Smid, A., Bartsch, I. & Grummt, I., Aug 25 1990, In : Nucleic acids research. 18, 16, p. 4727-4736 10 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Genes
Ribosomal DNA
Transcription Initiation Site
DNA-Binding Proteins
45 Citations (Scopus)

Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I

Schnapp, A., Clos, J., Hädelt, W., Schreck, R., Cvekl, A. & Grummt, I., Mar 25 1990, In : Nucleic acids research. 18, 6, p. 1385-1393 9 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Peptide Initiation Factors
Ribosomal DNA
rRNA Genes
Transcriptional Activation
78 Citations (Scopus)

Specific interaction of the murine transcription termination factor TTF I with class-I RNA polymerases

Kuhn, A., Bartsch, I. & Grummt, I., Jan 1 1990, In : Nature. 344, 6266, p. 559-562 4 p.

Research output: Contribution to journalArticle

RNA Polymerase I
RNA Polymerase II
Transcription Factors
Poly I
RNA Polymerase III
1989
46 Citations (Scopus)

3'-end formation of mouse pre-rRNA involves both transcription termination and a specific processing reaction.

Kuhn, A. & Grummt, I., Feb 1989, In : Genes & development. 3, 2, p. 224-231 8 p.

Research output: Contribution to journalArticle

RNA Precursors
RNA Polymerase I
Cell-Free System
Guanine
Ribosomal DNA
4 Citations (Scopus)

Transcriptional enhancement by upstream activators is brought about by different molecular mechanisms for class I and II RNA polymerase genes

Schreck, R., Carey, M. F. & Grummt, I., Jan 1 1989, In : EMBO Journal. 8, 10, p. 3011-3017 7 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Transcription
Genes
Ribosomal DNA
Chemical activation
1988
44 Citations (Scopus)

Purification and characterization of TTFI, a factor that mediates termination of mouse ribosomal DNA transcription

Bartsch, I., Schoneberg, C. & Grummt, I., Jan 1 1988, In : Molecular and cellular biology. 8, 9, p. 3891-3897 7 p.

Research output: Contribution to journalArticle

Peptide Termination Factors
Genetic Templates
Molecular Sequence Data
Genetic Transcription
Ehrlich Tumor Carcinoma
33 Citations (Scopus)

The mouse ribosomal gene terminator consists of three functionally separable sequence elements.

Kuhn, A., Normann, A., Bartsch, I. & Grummt, I., Jan 1 1988, In : The EMBO journal. 7, 5, p. 1497-1502 6 p.

Research output: Contribution to journalArticle

RNA Precursors
Transcription
Genes
RNA Polymerase I
Cell-Free System
1987
44 Citations (Scopus)

A novel promoter in the mouse rDNA spacer is active in vivo and in vitro.

Kuhn, A. & Grummt, I., Nov 1987, In : The EMBO journal. 6, 11, p. 3487-3492 6 p.

Research output: Contribution to journalArticle

RNA Precursors
Ribosomal DNA
Genes
Genetic Promoter Regions
Transcription
26 Citations (Scopus)

Evolutionary changes of sequences and factors that direct transcription termination of human and mouse ribsomal genes.

Bartsch, I., Schoneberg, C. & Grummt, I., Jul 1987, In : Molecular and cellular biology. 7, 7, p. 2521-2529 9 p.

Research output: Contribution to journalArticle

Transcription Factors
Protein Sorting Signals
Genes
Ribosomal DNA
Base Pairing
9 Citations (Scopus)
Ribosomal DNA
Point Mutation
RNA Polymerase I
Carrier Proteins
Nucleotides
1986
81 Citations (Scopus)

A repeated 18 bp sequence motif in the mouse rDNA spacer mediates binding of a nuclear factor and transcription termination

Grummt, I., Rosenbauer, H., Niedermeyer, I., Maier, U. & Öhrlein, A., Jun 20 1986, In : Cell. 45, 6, p. 837-846 10 p.

Research output: Contribution to journalArticle

Sequence Deletion
Insertional Mutagenesis
RNA Precursors
Consensus Sequence
Transcription
85 Citations (Scopus)

A transcription terminator located upstream of the mouse rDNA initiation site affects rRNA synthesis

Grummt, I., Kuhn, A., Bartsch, I. & Rosenbauer, H., Dec 26 1986, In : Cell. 47, 6, p. 901-911 11 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Transcription Initiation Site
RNA Precursors
Transcription
Ribosomal DNA
30 Citations (Scopus)

The core promoter of mouse rDNA consists of two functionally distinct domains

Clos, J., Normann, A., Öhrlein, A. & Grummt, I., Oct 1 1986, In : Nucleic acids research. 14, 19, p. 7581-7596 16 p.

Research output: Contribution to journalArticle

Transcription Initiation Site
Ribosomal DNA
Point Mutation
Transcription Factors
Mutation
1985
38 Citations (Scopus)
RNA Polymerase I
Chloramphenicol O-Acetyltransferase
Gene Fusion
Ribosomal DNA
Moloney murine sarcoma virus
6 Citations (Scopus)

Functional RNA polymerase II promoters in solitary retroviral long terminal repeats (LTR-IS elements)

Köhrer, K., Grummt, I. & Horak, I., Apr 11 1985, In : Nucleic acids research. 13, 7, p. 2631-2645 15 p.

Research output: Contribution to journalArticle

DNA Transposable Elements
Terminal Repeat Sequences
RNA Polymerase II
Chloramphenicol
Transferases
74 Citations (Scopus)

Growth-dependent regulation of rRNA synthesis is mediated by a transcription initiation factor (TTF-IA)

Buttgereit, D., Pflugfelder, G. & Grummt, I., Nov 25 1985, In : Nucleic acids research. 13, 22, p. 8165-8180 16 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Peptide Initiation Factors
Transcription Factors
Enzymes
Growth
11 Citations (Scopus)

Spacer sequences downstream of the 28S RNA coding region are part of the mouse rDNA transcription unit

Grummt, I., Sorbaz, H., Hofmann, A. & Roth, E., Apr 11 1985, In : Nucleic acids research. 13, 7, p. 2293-2304 12 p.

Research output: Contribution to journalArticle

RNA Precursors
Ribosomal DNA
RNA
RNA Polymerase I
Nuclear RNA
112 Citations (Scopus)

Transcription of mouse rDNA terminates downstream of the 3′ end of 28S RNA and involves interaction of factors with repeated sequences in the 3′ spacer

Grummt, I., Maier, U., Öhrlein, A., Hassouna, N. & Bachellerie, J. P., Dec 1985, In : Cell. 43, 3 PART 2, p. 801-810 10 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Transcription
Ribosomal DNA
RNA
Pyrimidines
1984
78 Citations (Scopus)

Drastic rise of intracellular adenosine(5′)tetraphospho(5′)adenosine correlates with onset of DNA synthesis in eukaryotic cells

WEINMANN‐DORSCH, C., HEDL, A., GRUMMT, I., ALBERT, W., FERDINAND, FJ. J., FRIIS, R. R., PIERRON, G., MOLL, W. & GRUMMT, F., Jan 1984, In : European Journal of Biochemistry. 138, 1, p. 179-185 7 p.

Research output: Contribution to journalArticle

Eukaryotic Cells
DNA
S Phase
Cells
G1 Phase
40 Citations (Scopus)

In vitro mutagenesis and transcriptional analysis of a mouse ribosomal promoter element

Skinner, J. A., Ohrlein, A. & Grummt, I., Jan 1 1984, In : Proceedings of the National Academy of Sciences of the United States of America. 81, 7 I, p. 2137-2141 5 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Mutagenesis
Nucleotides
Cell-Free System
DNA
1983
9 Citations (Scopus)

Expression of an mRNA coding gene under the control of an RNA polymerase I promoter.

Fleischer, S. & Grummt, I., Dec 1 1983, In : EMBO Journal. 2, 12, p. 2319-2322 4 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Viral Tumor Antigens
Ribosomal DNA
Genes
Transcription
38 Citations (Scopus)

Formation of stable preinitiation complexes is a prerequisite for ribosomal DNA transcription in vitro

Wandelt, C. & Grummt, I., Jun 11 1983, In : Nucleic acids research. 11, 11, p. 3795-3809 15 p.

Research output: Contribution to journalArticle

Transcription
Ribosomal DNA
Histones
DNA
RNA Polymerase I
1982
59 Citations (Scopus)
RNA Polymerase I
136 Citations (Scopus)

Ribosomal RNA transcription in vitro is species specific

Grummt, I., Roth, E. & Paule, M. R., Dec 1 1982, In : Nature. 296, 5853, p. 173-174 2 p.

Research output: Contribution to journalArticle

Ribosomal RNA
Cell-Free System
RNA Polymerase I
DNA-Directed RNA Polymerases
Protozoan RNA
1981
43 Citations (Scopus)

Mapping of a mouse ribosomal DNA promoter by in vitro transcription

Grummt, I., Nov 25 1981, In : Nucleic acids research. 9, 22, p. 6093-6102 10 p.

Research output: Contribution to journalArticle

Ribosomal DNA
RNA Polymerase I
Cell-Free System
5' Flanking Region
Transcription Initiation Site
106 Citations (Scopus)
Genetic Transcription
RNA Polymerase I
Bacteriophage lambda
Ehrlich Tumor Carcinoma
Ribosomal RNA
42 Citations (Scopus)

The nucleotide sequence of the initiation region of the ribosomal transcription unit from mouse

Bach, R., Grummt, I. & Allet, B., Apr 10 1981, In : Nucleic acids research. 9, 7, p. 1559-1569 11 p.

Research output: Contribution to journalArticle

RNA Precursors
Ribosomal DNA
Polyphosphates
Ribosomal RNA
Enzyme Assays
1980
29 Citations (Scopus)

Structural organization of mouse rDNA: Comparison of transcribed and non-transcribed regions

Grummt, I. & Gross, H. J., Jan 1 1980, In : MGG Molecular & General Genetics. 177, 2, p. 223-229 7 p.

Research output: Contribution to journalArticle

Recombinant DNA
Nucleic Acid Repetitive Sequences
DNA Restriction Enzymes
Ribosomal DNA
Base Pairing
1979
46 Citations (Scopus)

Characterization of a cloned ribosomal fragment from mouse which contains the 18S coding region and adjacent spacer sequences

Grummt, I., Soellner, C. & Scholz, I., Apr 1 1979, In : Nucleic acids research. 6, 4, p. 1351-1369 19 p.

Research output: Contribution to journalArticle

Mouse
Fragment
Adjacent
Coding
Genes
18 Citations (Scopus)
Endonucleases
Ribonucleases
RNA
Chick Embryo
Enzymes
12 Citations (Scopus)

Ribosome Biosynthesis Is not Necessary for Initiation of DNA Replication

GRUMMT, F., GRUMMT, I. & MAYER, E., Jun 1979, In : European Journal of Biochemistry. 97, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

Biosynthesis
DNA Replication
Ribosomes
Cells
DNA
1977
49 Citations (Scopus)

Regulation of ATP Pools, rRNA and DNA Synthesis in 3T3 Cells in Response to Serum or Hypoxanthine

GRUMMT, F., PAUL, D. & GRUMMT, I., Jun 1977, In : European Journal of Biochemistry. 76, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

3T3 Cells
Hypoxanthine
Adenosine Triphosphate
DNA
Azaserine
3 Citations (Scopus)

The Effect of Cyclic Nucleotides on Cellular ATP Levels and Ribosomal RNA Synthesis in Ehrlich Ascites Cells

GRUMMT, F. & GRUMMT, I., Oct 1977, In : European Journal of Biochemistry. 79, 2, p. 387-393 7 p.

Research output: Contribution to journalArticle

Ribosomal RNA
Cyclic Nucleotides
Ascites
Adenosine Triphosphate
Azaserine
16 Citations (Scopus)

The Effects of Histidine Starvation on the Methylation of Ribosomal RNA

GRUMMT, I., Sep 1977, In : European Journal of Biochemistry. 79, 1, p. 133-141 9 p.

Research output: Contribution to journalArticle

Methylation
Ribosomal RNA
Starvation
Histidine
Ribosomes
1976
102 Citations (Scopus)

Amino acid starvation affects the initiation frequency of nucleolar RNA polymerase

Grummt, I., Smith, V. A. & Grummt, F., Mar 1976, In : Cell. 7, 3, p. 439-445 7 p.

Research output: Contribution to journalArticle

Cell Nucleolus
DNA-Directed RNA Polymerases
Starvation
Amino Acids
RNA
87 Citations (Scopus)

Control of nucleolar RNA synthesis by the intracellular pool sizes of ATP and GTP

Grummt, I. & Grummt, F., Mar 1976, In : Cell. 7, 3, p. 447-453 7 p.

Research output: Contribution to journalArticle

Guanosine Triphosphate
Adenosine Triphosphate
RNA
Nucleosides
Purine Nucleosides
43 Citations (Scopus)

Studies on the Role of Uncharged tRNA in Pleiotypic. Response of Animal Cells

GRUMMT, F. & GRUMMT, I., Apr 1976, In : European Journal of Biochemistry. 64, 1, p. 307-312 6 p.

Research output: Contribution to journalArticle

RNA, Transfer, His
Histidinol
Transfer RNA
Animals
Cells
1975
18 Citations (Scopus)

Methylation of Ribosomal‐Precursor RNA, Synthesized in vitro, by Isolated Rat‐Liver Nucleoli

GRUMMT, I., LOENING, U. E. & SLACK, J. M. W., Nov 1975, In : European Journal of Biochemistry. 59, 1, p. 313-318 6 p.

Research output: Contribution to journalArticle

Methylation
RNA
Ribosomal RNA
Ribose
In Vitro Techniques
36 Citations (Scopus)

Synthesis of RNA Molecules Larger than 45 S by Isolated Rat‐Liver Nucleoli

GRUMMT, I., Sep 1975, In : European Journal of Biochemistry. 57, 1, p. 159-167 9 p.

Research output: Contribution to journalArticle

RNA
Molecules
RNA Precursors
Transcription
Sedimentation
1974
37 Citations (Scopus)

ATPase and GTPase Activities Isolated from Rat Liver Ribosomes

Grummt, F., Grummt, I. & Erdmann, V. A., Apr 1974, In : European Journal of Biochemistry. 43, 2, p. 343-348 6 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Ribosomes
Liver
Adenosine Triphosphatases
Rats
11 Citations (Scopus)

Effects of TψCG on the enzymatic binding of eukaryotic and prokaryotic initiator tRNAs to rat liver ribosomes

Grummt, F., Grummt, I., Gross, H. J., Sprinzl, M., Richter, D. & Erdmann, V. A., May 15 1974, In : FEBS Letters. 42, 1, p. 15-17 3 p.

Research output: Contribution to journalArticle

Ultraviolet Spectrophotometry
Bacterial RNA
RNA, Transfer, Met
Nucleic Acid Conformation
Drug Receptors
5 Citations (Scopus)

Studies on free and 5 S RNA-bound ribosomal GTPase and ATPase

Grummt, F. & Grummt, I., Jun 15 1974, In : FEBS Letters. 42, 3, p. 343-346 4 p.

Research output: Contribution to journalArticle

Ultraviolet Spectrophotometry
Drug Stability
Drug Receptors
Ribosomal RNA
Density Gradient Centrifugation