• 2187 Citations
  • 25 h-Index
20012019
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Fingerprint Dive into the research topics where Jian Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Neoplasms Medicine & Life Sciences
Transforming Growth Factors Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Hepatocellular Carcinoma Medicine & Life Sciences
Spectrin Medicine & Life Sciences
Hypoxia-Inducible Factor 1 Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Apoptosis Medicine & Life Sciences

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Research Output 2001 2019

  • 2187 Citations
  • 25 h-Index
  • 40 Article
  • 4 Review article
  • 1 Chapter
  • 1 Comment/debate
2 Citations (Scopus)

Immunomodulatory TGF-β Signaling in Hepatocellular Carcinoma

Chen, J., Gingold, J. A. & Su, X., Nov 2019, In : Trends in Molecular Medicine. 25, 11, p. 1010-1023 14 p.

Research output: Contribution to journalReview article

Open Access
Transforming Growth Factor beta
Hepatocellular Carcinoma
Immunotherapy
Biomarkers
Inflammation
17 Citations (Scopus)

Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway

Chen, J., Zaidi, S., Rao, S., Chen, J. S., Phan, L., Farci, P., Su, X., Shetty, K., White, J., Zamboni, F., Wu, X., Rashid, A., Pattabiraman, N., Mazumder, R., Horvath, A., Wu, R. C., Li, S., Xiao, C., Deng, C. X., Wheeler, D. A. & 3 others, Mishra, B., Akbani, R. & Mishra, L., Jan 1 2018, In : Gastroenterology. 154, 1, p. 195-210 16 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Gene Expression Profiling
Transforming Growth Factor beta
Hepatocellular Carcinoma
Genome
25 Citations (Scopus)

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

Sun, C., Yin, J., Fang, Y., Chen, J., Jeong, K. J., Chen, X., Vellano, C. P., Ju, Z., Zhao, W., Zhang, D., Lu, Y., Meric-Bernstam, F., Yap, T. A., Hattersley, M., O'Connor, M. J., Chen, H., Fawell, S., Lin, S. Y., Peng, G. & Mills, G. B., Mar 12 2018, In : Cancer Cell. 33, 3, p. 401-416.e8

Research output: Contribution to journalArticle

Homologous Recombination
Mutation
Poly(ADP-ribose) Polymerase Inhibitors
Protein C
Neoplasms
11 Citations (Scopus)

Genomic Profiling and Metabolic Homeostasis in Primary Liver Cancers

Gingold, J. A., Zhu, D., Lee, D. F., Kaseb, A. & Chen, J., Apr 1 2018, In : Trends in Molecular Medicine. 24, 4, p. 395-411 17 p.

Research output: Contribution to journalReview article

Cholangiocarcinoma
Liver Neoplasms
Hepatocellular Carcinoma
Homeostasis
Molecular Targeted Therapy
300 Citations (Scopus)

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

The Cancer Genome Atlas Research Network, Jun 15 2017, In : Cell. 169, 7, p. 1327-1341.e23

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Genes
DNA
MicroRNAs
Gene expression