John Frederick de Groot


  • 8769 Citations
  • 40 h-Index
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Fingerprint Dive into the research topics where John Frederick de Groot is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Glioblastoma Medicine & Life Sciences
Glioma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
temozolomide Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Brain Neoplasms Medicine & Life Sciences
Survival Medicine & Life Sciences
Vascular Endothelial Growth Factor A Medicine & Life Sciences

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Research Output 1997 2019

5 Citations (Scopus)

Buparlisib in patients with recurrent glioblastoma harboring phosphatidylinositol 3-kinase pathway activation: An open-label, multicenter, multi-arm, phase II trial

Wen, P. Y., Touat, M., Alexander, B. M., Mellinghoff, I. K., Ramkissoon, S., McCluskey, C. S., Pelton, K., Haidar, S., Basu, S. S., Gaffey, S. C., Brown, L. E., Martinez-Ledesma, J. E., Wu, S., Kim, J., Wei, W., Park, M. A., Huse, J., Kuhn, J. G., Rinne, M. L., Colman, H. & 24 others, Agar, N. Y. R., Omuro, A. M., DeAngelis, L. M., Gilbert, M. R., de Groot, J. F., Cloughesy, T. F., Chi, A. S., Roberts, T. M., Zhao, J. J., Lee, E. Q., Nayak, L., Heath, J. R., Horky, L. L., Batchelor, T. T., Beroukhim, R., Chang, S. M., Ligon, A. H., Dunn, I. F., Koul, D., Young, G. S., Prados, M. D., Reardon, D. A., Alfred Yung, W. K. & Ligon, K. L., Mar 20 2019, In : Journal of Clinical Oncology. 37, 9, p. 741-750 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase

Clinical trial participation of patients with glioblastoma at The University of Texas MD Anderson Cancer Center

Harrison, R., Anderson, M. D., Cachia, D., Kamiya Matsuoka, C., Weathers, S-P., O'Brien, B. J., Penas-Prado, M., Yung, W. K. A., Wu, J., Yuan, Y. & de Groot, J. F., May 1 2019, In : European Journal of Cancer. 112, p. 83-93 11 p.

Research output: Contribution to journalArticle

Patient Participation
Clinical Trials
Clinical Protocols

Disparities along the glioblastoma clinical trials landscape

Ludmir, E. B., Mandel, J. J., McAleer, M. F. & de Groot, J. F., Feb 14 2019, In : Neuro-oncology. 21, 2, p. 285-286 2 p.

Research output: Contribution to journalLetter

Open Access
Clinical Trials

Effect of health disparities on overall survival of patients with glioblastoma

Mandel, J. J., Youssef, M., Nam, J., Patel, A. J., Jalali, A., Ludmir, E. B., Liu, D., Wu, J., Armstrong, G., Huse, J., Bondy, M. & de Groot, J. F., Apr 15 2019, In : Journal of neuro-oncology. 142, 2, p. 365-374 10 p.

Research output: Contribution to journalArticle

Standard of Care
County Hospitals

Erratum: Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair (Cancer Cell (2019)35(3)(504–518.e7), (S1535610819300546), (10.1016/j.ccell.2019.01.020))

Ma, J., Benitez, J. A., Li, J., Miki, S., Ponte de Albuquerque, C., Galatro, T., Orellana, L., Zanca, C., Reed, R., Boyer, A., Koga, T., Varki, N. M., Fenton, T. R., Nagahashi Marie, S. K., Lindahl, E., Gahman, T. C., Shiau, A. K., Zhou, H., de Groot, J. F., Sulman, E. P. & 4 others, Cavenee, W. K., Kolodner, R. D., Chen, C. C. & Furnari, F. B., May 13 2019, In : Cancer cell. 35, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Radiation Tolerance
DNA Repair