Jun-ichi Abe &ndash; Research Output

1991

Rapid quantitation of serum myoglobin by latex agglutination turbidimetry

Abe, J., Yamaguchi, T., Isshiki, T., Naka, H., Kawada, Y. & Katayama, Y., Nov 9 1991, In : Clinica Chimica Acta. 203, 1, p. 95-96 2 p.

Research output: Contribution to journal › Letter

Latex Fixation Tests

Nephelometry and Turbidimetry

Myoglobin

Agglutination

Latex

1992

2 Citations (Scopus)

Neuronal Hyaline Inclusions Observed in an Autopsy Case of Behçet's Disease

Iihara, K., Abe, J. & Murakami, T., Jan 1 1992, In : Pathology International. 42, 6, p. 432-439 8 p.

Research output: Contribution to journal › Article

Hyalin

Lewy Bodies

Autopsy

Parkinson Disease

Oral Ulcer

1993

25 Citations (Scopus)

Angiotensin converting enzyme inhibitors or DuP753 prevent neointimal formation following balloon injury with single topical or multiple systemic application

Taguchi, J., Abe, J., Okazaki, H., Ochiai, M., Ohno, M., Takuwa, Y. & Kurokawa, K., Oct 29 1993, In : Biochemical and biophysical research communications. 196, 2, p. 969-974 6 p.

Research output: Contribution to journal › Article

Balloons

Angiotensin-Converting Enzyme Inhibitors

UCON 50-HB-5100

Angiotensin II

Wounds and Injuries

46 Citations (Scopus)

L-arginine inhibits neointimal formation following balloon injury

Taguchi, J., Abe, J., Okazaki, H., Takuwa, Y. & Kurokawa, K., Jan 1 1993, In : Life Sciences. 53, 23

Research output: Contribution to journal › Article

Balloons

Arginine

Nitric Oxide

Wounds and Injuries

Blood pressure

14 Citations (Scopus)

Myocardial reperfusion can be predicted by myoglobin/creatine kinase ratio of a single blood sample obtained at the time of admission

Abe, J., Yamaguchi, T., Isshiki, T., Naka, H., Taguchi, J., Ishizaka, N., Kurokawa, K., Saeki, F., Ishizaka, Y., Ui, K., Ikari, Y., Somitsu, Y., Hashimoto, H. & Kashida, M., Jan 1 1993, In : American Heart Journal. 126, 2, p. 279-285 7 p.

Research output: Contribution to journal › Article

Myocardial Reperfusion

Myoglobin

Creatine Kinase

Myocardial Infarction

Reperfusion

1994

145 Citations (Scopus)

A Fumagillin Derivative Angiogenesis Inhibitor, AGM-1470, Inhibits Activation of Cyclin-dependent Kinases and Phosphorylation of Retinoblastoma Gene Product but not Protein Tyrosyl Phosphorylation or Protooncogene Expression in Vascular Endothelial Cells

Abe, J., Zhou, W. & Takuwa, Y., Jan 1 1994, In : Cancer Research. 54, 13, p. 3407-3412 6 p.

Research output: Contribution to journal › Article

Retinoblastoma Genes

Angiogenesis Inhibitors

Cyclin-Dependent Kinases

Endothelial Cells

Phosphorylation

49 Citations (Scopus)

Angiographic follow-up after successful percutaneous coronary angioplasty for chronic total coronary occlusion: Experience in 110 consecutive patients

Ishizaka, N., Issiki, T., Saeki, F., Ishizaka, Y., Ikari, Y., Abe, J., Soumitsu, Y., Hashimoto, H., Masaki, K. & Yamaguchi, T., Jan 1 1994, In : American Heart Journal. 127, 1, p. 8-12 5 p.

Research output: Contribution to journal › Article

Coronary Balloon Angioplasty

Coronary Occlusion

Angioplasty

Angiography

Coronary Artery Disease

100 Citations (Scopus)

Suppression of neointimal smooth muscle cell accumulation in vivo by antisense cdc2 and cdk2 oligonucleotides in rat carotid artery

Abe, J., Zhou, W., Taguchi, J. I., Takuwa, N., Miki, K., Okazaki, H., Kurokawa, K., Kumada, M. & Takuwa, Y., Jan 15 1994, In : Biochemical and biophysical research communications. 198, 1, p. 16-24 9 p.

Research output: Contribution to journal › Article

Tunica Intima

Carotid Arteries

Oligonucleotides

Smooth Muscle Myocytes

Muscle

11 Citations (Scopus)

Topical application of AT₁ receptor antagonists prevents medial and neointimal proliferation after balloon injury

Taguchi, J., Abe, J., Ohno, M., Schwartz, S. M. & Kurokawa, K., 1994, In : Blood Pressure, Supplement. 3, 5, p. 38-42 5 p.

Research output: Contribution to journal › Article

Neointima

UCON 50-HB-5100

Angiotensin II

Arginine

Wounds and Injuries

1996

363 Citations (Scopus)

Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase

Abe, J., Kusuhara, M., Ulevitch, R. J., Berk, B. C. & Lee, J. D., Jul 30 1996, In : Journal of Biological Chemistry. 271, 28, p. 16586-16590 5 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase 1

Oxidation-Reduction

Phosphotransferases

Mitogen-Activated Protein Kinases

Chemical activation

9 Citations (Scopus)

Thrombotic occlusion of the coronary artery associated with accidental detachment of undeployed Palmaz-Schatz stent

Shiojima, I., Ikari, Y., Abe, J., Ishizaka, N., Maemura, K., Kurihara, H., Isshiki, T. A., Suma, H., Saeki, H., Hara, K., Tamura, T. & Yamaguchi, T., Aug 1 1996, In : Catheterization and Cardiovascular Diagnosis. 38, 4, p. 360-362 3 p.

Research output: Contribution to journal › Article

Stents

Coronary Vessels

Coronary Occlusion

Therapeutics

1997

46 Citations (Scopus)

Angiotensin II stimulates p90(rsk) in vascular smooth muscle cells: A potential Na⁺-H⁺ exchanger kinase

Takahashi, E., Abe, J. & Berk, B. C., Jan 1 1997, In : Circulation Research. 81, 2, p. 268-273 6 p.

Research output: Contribution to journal › Article

90-kDa Ribosomal Protein S6 Kinases

Sodium-Hydrogen Antiporter

Vascular Smooth Muscle

Angiotensin II

Smooth Muscle Myocytes

Angiotensin II Stimulates p90rsk2 in vascular smooth muscle cells: A potential Na+/H+ exchanger kinase

Takahashi, E., Abe, J. I. & Berk, B. C., Dec 1 1997, In : FASEB Journal. 11, 3, p. A500

Research output: Contribution to journal › Article

Sodium-Hydrogen Antiporter

Vascular Smooth Muscle

Angiotensin II

Smooth Muscle Myocytes

Muscle

246 Citations (Scopus)

c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 (BMK1)

Abe, J., Takahashi, M., Ishida, M., Lee, J. D. & Berk, B. C., Aug 15 1997, In : Journal of Biological Chemistry. 272, 33, p. 20389-20394 6 p.

Research output: Contribution to journal › Article

Oxidative stress

Mitogen-Activated Protein Kinase 1

Oxidative Stress

Chemical activation

src-Family Kinases

53 Citations (Scopus)

Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: A link between angiotensin II and intimal thickening

Abe, J., Deguchi, J. O., Matsumoto, T., Takuwa, N., Noda, M., Ohno, M., Makuuchi, M., Kurokawa, K. & Takuwa, Y., Jan 1 1997, In : Circulation. 96, 6, p. 1906-1913 8 p.

Research output: Contribution to journal › Article

Tunica Intima

Platelet-Derived Growth Factor Receptors

Angiotensin II

Platelet-Derived Growth Factor

Arteries

1998

127 Citations (Scopus)

p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells effects on Na⁺/H⁺ exchange and ERK1/2

Kusuhara, M., Takahashi, E., Peterson, T. E., Abe, J., Ishida, M., Han, J., Ulevitch, R. & Berk, B. C., Oct 19 1998, In : Circulation Research. 83, 8, p. 824-831 8 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase 3

Mitogen-Activated Protein Kinase 1

Vascular Smooth Muscle

Angiotensin II

Smooth Muscle Myocytes

234 Citations (Scopus)

Reactive oxygen species as mediators of signal transduction in cardiovascular disease

Abe, J. & Berk, B. C., Feb 1 1998, In : Trends in Cardiovascular Medicine. 8, 2, p. 59-64 6 p.

Research output: Contribution to journal › Review article

Reactive Oxygen Species

Signal Transduction

Cardiovascular Diseases

Chemical Phenomena

Biological Phenomena

15 Citations (Scopus)

Tyrosine phosphorylation of platelet derived growth factor β receptors in coronary artery lesions: Implications for vascular remodelling after directional coronary atherectomy and unstable angina pectoris

Abe, J., Deguchi, J., Takuwa, Y., Hara, K., Ikari, Y., Tamura, T., Ohno, M. & Kurokawa, K., Jan 1 1998, In : Heart. 79, 4, p. 400-406 7 p.

Research output: Contribution to journal › Article

Coronary Atherectomy

Platelet-Derived Growth Factor Receptors

Unstable Angina

Tyrosine

Coronary Vessels

1999

74 Citations (Scopus)

Differential regulation of p90 ribosomal S6 kinase and big mitogen- activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts

Takeishi, Y., Abe, J., Lee, J. D., Kawakatsu, H., Walsh, R. A. & Berk, B. C., Dec 3 1999, In : Circulation research. 85, 12, p. 1164-1172 9 p.

Research output: Contribution to journal › Article

90-kDa Ribosomal Protein S6 Kinases

MAP Kinase Kinase 1

Mitogen-Activated Protein Kinase 1

Reperfusion

Guinea Pigs

178 Citations (Scopus)

Fyn and JAK2 mediate Ras activation by reactive oxygen species

Abe, J. & Berk, B. C., Jul 23 1999, In : Journal of Biological Chemistry. 274, 30, p. 21003-21010 8 p.

Research output: Contribution to journal › Article

Reactive Oxygen Species

Chemical activation

Extracellular Signal-Regulated MAP Kinases

Fibroblasts

Transgenic Mice

5 Citations (Scopus)

Inhibitory effects of trapidil on PDGF signaling in balloon-injured rat carotid artery

Deguchi, J. O., Abe, J., Makuuchi, M. & Takuwa, Y., Nov 19 1999, In : Life Sciences. 65, 26, p. 2791-2799 9 p.

Research output: Contribution to journal › Article

Trapidil

Balloons

Platelet-Derived Growth Factor

Carotid Arteries

Rats

198 Citations (Scopus)

p90(RSK) is a serum-stimulated Na⁺/H⁺ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na⁺/H⁺ exchanger isoform-1

Takáhashi, E., Abe, J., Gallis, B., Aebersold, R., Spring, D. J., Krebs, E. G. & Berk, B. C., Jul 16 1999, In : Journal of Biological Chemistry. 274, 29, p. 20206-20214 9 p.

Research output: Contribution to journal › Article

90-kDa Ribosomal Protein S6 Kinases

Sodium-Hydrogen Antiporter

Phosphorylation

Serine

Protein Isoforms

42 Citations (Scopus)

Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injury

Deguchi, J., Namba, T., Hamada, H., Nakaoka, T., Abe, J., Sato, O., Miyata, T., Makuuchi, M., Kurokawa, K. & Takuwa, Y., Jun 1 1999, In : Gene Therapy. 6, 6, p. 956-965 10 p.

Research output: Contribution to journal › Article

Proto-Oncogene Proteins c-sis

Adenoviridae

Smooth Muscle

Wounds and Injuries

Platelet-Derived Growth Factor Receptors

2000

120 Citations (Scopus)

Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras

Jun-Ichi, A., Okuda, M., Huang, Q., Yoshizumi, M. & Berk, B. C., Jan 21 2000, In : Journal of Biological Chemistry. 275, 3, p. 1739-1748 10 p.

Research output: Contribution to journal › Article

90-kDa Ribosomal Protein S6 Kinases

Reactive Oxygen Species

Chemical activation

Fibroblasts

Signal transduction

98 Citations (Scopus)

Role of mitogen-activated protein kinases in ischemia and reperfusion injury: The good and the bad

Abe, J., Baines, C. P. & Berk, B. C., Mar 31 2000, In : Circulation research. 86, 6, p. 607-609 3 p.

Research output: Contribution to journal › Editorial

Myocardial Reperfusion Injury

Mitogen-Activated Protein Kinases

Reperfusion Injury

Cardiac Myocytes

Myocardial Ischemia

229 Citations (Scopus)

Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species

Yoshizumi, M., Abe, J. I., Haendeler, J., Huang, Q. & Berk, B. C., Apr 21 2000, In : Journal of Biological Chemistry. 275, 16, p. 11706-11712 7 p.

Research output: Contribution to journal › Article

JNK Mitogen-Activated Protein Kinases

Reactive Oxygen Species

Phosphotransferases

Chemical activation

Mitogen-Activated Protein Kinase 3

2001

102 Citations (Scopus)

14-3-3 Binding to Na⁺/H⁺ Exchanger Isoform-1 is Associated with Serum-dependent Activation of Na⁺/H⁺ Exchange

Lehoux, S., Abe, J. I., Florian, J. A. & Berk, B. C., May 11 2001, In : Journal of Biological Chemistry. 276, 19, p. 15794-15800 7 p.

Research output: Contribution to journal › Article

Sodium-Hydrogen Antiporter

Ion exchange

Protein Isoforms

Chemical activation

Serum

5 Citations (Scopus)

Bcr in vascular smooth muscle cells involvement of Ras and Raf-1 activation by Bcr

Abe, J. I., Che, W., Yoshizumi, M., Huang, Q., Glassman, M., Ohta, S., Wu, Y., Arlinghaus, R. & Berk, B. C., Jan 1 2001, In : Annals of the New York Academy of Sciences. 947, p. 341-343 3 p.

Research output: Contribution to journal › Article

Vascular Smooth Muscle

Smooth Muscle Myocytes

Muscle

Phosphotransferases

Chemical activation

180 Citations (Scopus)

Endothelial atheroprotective and anti-inflammatory mechanisms

Berk, B. C., Abe, J., Min, W., Surapisitchat, J. & Yan, C., Jan 1 2001, In : Annals of the New York Academy of Sciences. 947, p. 93-111 19 p.

Research output: Contribution to journal › Article

Endothelial cells

Anti-Inflammatory Agents

Tumor Necrosis Factor-alpha

Endothelial Cells

Phosphotransferases

118 Citations (Scopus)

Molecular Cloning of Mouse ERK5/BMK1 Splice Variants and Characterization of ERK5 Functional Domains

Yan, C., Luo, H., Lee, J. D., Abe, J. & Berk, B. C., Apr 6 2001, In : Journal of Biological Chemistry. 276, 14, p. 10870-10878 9 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase 7

Cloning

Molecular Cloning

Complementary DNA

Phosphotransferases

14 Citations (Scopus)

p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells

Che, W., Abe, J. I., Yoshizumi, M., Huang, Q., Glassman, M., Ohta, S., Melaragno, M. G., Poppa, V., Yan, C., Lerner-Marmarosh, N., Zhang, C., Wu, Y., Arlinghaus, R. & Berk, B. C., Sep 18 2001, In : Circulation. 104, 12, p. 1399-1406 8 p.

Research output: Contribution to journal › Article

Platelet-Derived Growth Factor

Extracellular Signal-Regulated MAP Kinases

Vascular Smooth Muscle

Smooth Muscle Myocytes

Phosphotransferases

107 Citations (Scopus)

Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: Comparison with acute mechanical stretch

Takeishi, Y., Huang, Q., Abe, J. I., Glassman, M., Che, W., Lee, J. D., Kawakatsu, H., Lawrence, E. G., Hoit, B. D., Berk, B. C. & Walsh, R. A., Jan 1 2001, In : Journal of Molecular and Cellular Cardiology. 33, 9, p. 1637-1648 12 p.

Research output: Contribution to journal › Article

Cardiomegaly

Mitogen-Activated Protein Kinases

Mitogen-Activated Protein Kinase 7

Heart Failure

Pressure

42 Citations (Scopus)

Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: Modulation of MAP kinases activation by ischemic preconditioning

Takeishi, Y., Huang, Q., Wang, T., Glassman, M., Yoshizumi, M., Baines, C. P., Lee, J. D., Kawakatsu, H., Che, W., Lerner-Marmarosh, N., Zhang, C., Yan, C., Ohta, S., Walsh, R. A., Berk, B. C. & Abe, J. I., Jan 1 2001, In : Journal of Molecular and Cellular Cardiology. 33, 11, p. 1989-2005 17 p.

Research output: Contribution to journal › Article

Ischemic Preconditioning

src-Family Kinases

Mitogen-Activated Protein Kinases

Adenosine

Myocardium

2002

77 Citations (Scopus)

Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy

Takeishi, Y., Huang, Q., Abe, J. I., Che, W., Lee, J. D., Kawakatsu, H., Hoit, B. D., Berk, B. C. & Walsh, R. A., Jan 10 2002, In : Cardiovascular Research. 53, 1, p. 131-137 7 p.

Research output: Contribution to journal › Article

90-kDa Ribosomal Protein S6 Kinases

Mitogen-Activated Protein Kinase 7

Dilated Cardiomyopathy

Mitogen-Activated Protein Kinases

Phosphotransferases

66 Citations (Scopus)

Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway

Tai, L. K., Okuda, M., Abe, J., Yan, C. & Berk, B. C., Nov 1 2002, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 22, 11, p. 1790-1796 7 p.

Research output: Contribution to journal › Article

Proline

Protein-Tyrosine Kinases

Crk-Associated Substrate Protein

Reactive Oxygen Species

Phosphorylation

6 Citations (Scopus)

Hypoxia and HIF-1α stability: Another stress-sensing mechanism for Shc

Abe, J. & Berk, B. C., Jul 12 2002, In : Circulation research. 91, 1, p. 4-6 3 p.

Research output: Contribution to journal › Editorial

Signal Transducing Adaptor Proteins

Alpha Subunit Hypoxia-Inducible Factor 1

Vesicular Transport Adaptor Proteins

Hypoxia-Inducible Factor 1

Cell Hypoxia

156 Citations (Scopus)

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: Role of Gab1 and MEKK3 in TNF-α-induced c-Jun and NF-κB activation and adhesion molecule expression

Che, W., Lerner-Marmarosh, N., Huang, Q., Osawa, M., Ohta, S., Yoshizumi, M., Glassman, M., Lee, J. D., Yan, C., Berk, B. C. & Abe, J. I., Jun 14 2002, In : Circulation research. 90, 11, p. 1222-1230 9 p.

Research output: Contribution to journal › Article

Somatomedins

Endothelial Cells

Tumor Necrosis Factor-alpha

Transcriptional Activation

Blood Vessels

26 Citations (Scopus)

Protein kinase C-α and protein kinase C-ε are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor

Saito, Y., Hojo, Y., Tanimoto, T., Abe, J. I. & Berk, B. C., Jun 28 2002, In : Journal of Biological Chemistry. 277, 26, p. 23216-23222 7 p.

Research output: Contribution to journal › Article

Phosphorylation

Platelet-Derived Growth Factor

Type C Phospholipases

Protein Kinase C

Binders

13 Citations (Scopus)

The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation.

Huang, Q., Lerner-Marmarosh, N., Che, W., Ohta, S., Osawa, M., Yoshizumi, M., Glassman, M., Yan, C., Berk, B. C. & Abe, J. I., Aug 9 2002, In : The Journal of biological chemistry. 277, 32, p. 29330-29341 12 p.

Research output: Contribution to journal › Article

src Homology Domains

Phosphoric Monoester Hydrolases

Chemical activation

Signal transduction

Protein Tyrosine Phosphatases

2003

29 Citations (Scopus)

Inhibition of tumor necrosis factor-α-induced SHP-2 phosphatase activity by shear stress: A mechanism to reduce endothelial inflammation

Lerner-Marmarosh, N., Yoshizumi, M., Che, W., Surapisitchat, J., Kawakatsu, H., Akaike, M., Ding, B., Huang, Q., Yan, C., Berk, B. C. & Abe, J. I., Oct 1 2003, In : Arteriosclerosis, thrombosis, and vascular biology. 23, 10, p. 1775-1781 7 p.

Research output: Contribution to journal › Article

Phosphoric Monoester Hydrolases

Tumor Necrosis Factor-alpha

Inflammation

src-Family Kinases

JNK Mitogen-Activated Protein Kinases

90 Citations (Scopus)

Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase 1/ERK5 but not ERK1/2 kinase activation

Cameron, S. J., Malik, S., Akaike, M., Lerner-Marmarosh, N., Yan, C., Lee, J. D., Abe, J. & Yang, J., May 16 2003, In : Journal of Biological Chemistry. 278, 20, p. 18682-18688 7 p.

Research output: Contribution to journal › Article

Connexin 43

Mitogen-Activated Protein Kinase 3

Gap Junctions

Mitogen-Activated Protein Kinase 1

Epidermal Growth Factor

98 Citations (Scopus)

Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells

Aizawa, T., Wei, H., Miano, J. M., Abe, J., Berk, B. C. & Yan, C., Sep 5 2003, In : Circulation research. 93, 5, p. 406-413 8 p.

Research output: Contribution to journal › Article

S-Nitroso-N-Acetylpenicillamine

C-Type Natriuretic Peptide

Phosphoric Diester Hydrolases

Vascular Smooth Muscle

Smooth Muscle Myocytes

65 Citations (Scopus)

Stress and vascular responses: Atheroprotective effect of laminar fluid shear stress in endothelial cells: Possible role of mitogen-activated protein kinases

Yoshizumi, M., Abe, J., Tsuchiya, K., Berk, B. C. & Tamaki, T., Mar 1 2003, In : Journal Pharmacological Sciences. 91, 3, p. 172-176 5 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinases

Blood Vessels

Endothelial Cells

Tumor Necrosis Factor-alpha

Umbilical Veins

2004

31 Citations (Scopus)

Activation of big MAP kinase 1 (BMK1/ERK5) inhibits cardiac injury after myocardial ischemia and reperfusion

Cameron, S. J., Itoh, S., Baines, C. P., Zhang, C., Ohta, S., Che, W., Glassman, M., Lee, J. D., Yan, C., Yang, J. & Abe, J., May 21 2004, In : FEBS Letters. 566, 1-3, p. 255-260 6 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase 7

Myocardial Reperfusion

Transgenic Mice

Reperfusion

Myocardial Ischemia

28 Citations (Scopus)

Differential Role of MEK5α and MEK5β in BMK1/ERK5 Activation

Cameron, S. J., Abe, J., Malik, S., Che, W. & Yang, J., Jan 9 2004, In : Journal of Biological Chemistry. 279, 2, p. 1506-1512 7 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase 1

Mitogen-Activated Protein Kinase 7

Phosphorylation

Phosphotransferases

Chemical activation

35 Citations (Scopus)

ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): Role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear accumulation

Osawa, M., Itoh, S., Ohta, S., Huang, Q., Berk, B. C., Marmarosh, N. L., Che, W., Ding, B., Yan, C. & Abe, J. I., Jul 9 2004, In : Journal of Biological Chemistry. 279, 28, p. 29691-29699 9 p.

Research output: Contribution to journal › Article

GRB2 Adaptor Protein

NFI Transcription Factors

Nuclear Localization Signals

Binders

Intercellular Signaling Peptides and Proteins

28 Citations (Scopus)

Pleckstrin Homology and Phosphotyrosine-binding Domain-dependent Membrane Association and Tyrosine Phosphorylation of Dok-4, an Inhibitory Adapter Molecule Expressed in Epithelial Cells

Bedirian, A., Baldwin, C., Abe, J., Takano, T. & Lemay, S., Apr 30 2004, In : Journal of Biological Chemistry. 279, 18, p. 19335-19349 15 p.

Research output: Contribution to journal › Article

Phosphotyrosine

Phosphorylation

Tyrosine

Epithelial Cells

Membranes

88 Citations (Scopus)

The hinge-helix 1 region of peroxisome proliferator-activated receptor γ1 (PPARγ1) mediates interaction with extracellular signal-regulated kinase 5 and PPARγ1 transcriptional activation: Involvement in flow-induced PPARγ activation in endothelial cells

Akaike, M., Che, W., Marmarosh, N. L., Ohta, S., Osawa, M., Ding, B., Berk, B. C., Yan, C. & Abe, J., Oct 1 2004, In : Molecular and Cellular Biology. 24, 19, p. 8691-8704 14 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase 7

Peroxisome Proliferator-Activated Receptors

Transcriptional Activation

Endothelial Cells

Phosphotransferases

2005

43 Citations (Scopus)

Adenovirus-mediated overexpression of diacylglycerol kinase-ζ inhibits endothelin-1-induced cardiomyocyte hypertrophy

Takahashi, H., Takeishi, Y., Seidler, T., Arimoto, T., Akiyama, H., Hozumi, Y., Koyama, Y., Shishido, T., Tsunoda, Y., Niizeki, T., Nozaki, N., Abe, J. I., Hasenfuss, G., Goto, K. & Kubota, I., Mar 29 2005, In : Circulation. 111, 12, p. 1510-1516 7 p.

Research output: Contribution to journal › Article

Diacylglycerol Kinase

Endothelin-1

Cardiac Myocytes

Adenoviridae

Hypertrophy

92 Citations (Scopus)

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis

Ding, B., Abe, J. I., Wei, H., Xu, H., Che, W., Aizawa, T., Liu, W., Molina, C. A., Sadoshima, J., Blaxall, B. C., Berk, B. C. & Yan, C., Oct 11 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 41, p. 14771-14776 6 p.

Research output: Contribution to journal › Article

Type 3 Cyclic Nucleotide Phosphodiesterases

Phosphoric Diester Hydrolases

Cardiac Myocytes

Apoptosis

Up-Regulation