• 6953 Citations
  • 49 h-Index
1991 …2019
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Research Output 1991 2019

2002
156 Citations (Scopus)

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: Role of Gab1 and MEKK3 in TNF-α-induced c-Jun and NF-κB activation and adhesion molecule expression

Che, W., Lerner-Marmarosh, N., Huang, Q., Osawa, M., Ohta, S., Yoshizumi, M., Glassman, M., Lee, J. D., Yan, C., Berk, B. C. & Abe, J. I., Jun 14 2002, In : Circulation research. 90, 11, p. 1222-1230 9 p.

Research output: Contribution to journalArticle

Somatomedins
Endothelial Cells
Tumor Necrosis Factor-alpha
Transcriptional Activation
Blood Vessels
26 Citations (Scopus)

Protein kinase C-α and protein kinase C-ε are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor

Saito, Y., Hojo, Y., Tanimoto, T., Abe, J. I. & Berk, B. C., Jun 28 2002, In : Journal of Biological Chemistry. 277, 26, p. 23216-23222 7 p.

Research output: Contribution to journalArticle

Phosphorylation
Platelet-Derived Growth Factor
Type C Phospholipases
Protein Kinase C
Binders
13 Citations (Scopus)

The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation.

Huang, Q., Lerner-Marmarosh, N., Che, W., Ohta, S., Osawa, M., Yoshizumi, M., Glassman, M., Yan, C., Berk, B. C. & Abe, J. I., Aug 9 2002, In : The Journal of biological chemistry. 277, 32, p. 29330-29341 12 p.

Research output: Contribution to journalArticle

src Homology Domains
Phosphoric Monoester Hydrolases
Chemical activation
Signal transduction
Protein Tyrosine Phosphatases
2001
102 Citations (Scopus)

14-3-3 Binding to Na+/H+ Exchanger Isoform-1 is Associated with Serum-dependent Activation of Na+/H+ Exchange

Lehoux, S., Abe, J. I., Florian, J. A. & Berk, B. C., May 11 2001, In : Journal of Biological Chemistry. 276, 19, p. 15794-15800 7 p.

Research output: Contribution to journalArticle

Sodium-Hydrogen Antiporter
Ion exchange
Protein Isoforms
Chemical activation
Serum
5 Citations (Scopus)

Bcr in vascular smooth muscle cells involvement of Ras and Raf-1 activation by Bcr

Abe, J. I., Che, W., Yoshizumi, M., Huang, Q., Glassman, M., Ohta, S., Wu, Y., Arlinghaus, R. & Berk, B. C., Jan 1 2001, In : Annals of the New York Academy of Sciences. 947, p. 341-343 3 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
Phosphotransferases
Chemical activation
180 Citations (Scopus)

Endothelial atheroprotective and anti-inflammatory mechanisms

Berk, B. C., Abe, J., Min, W., Surapisitchat, J. & Yan, C., Jan 1 2001, In : Annals of the New York Academy of Sciences. 947, p. 93-111 19 p.

Research output: Contribution to journalArticle

Endothelial cells
Anti-Inflammatory Agents
Tumor Necrosis Factor-alpha
Endothelial Cells
Phosphotransferases
118 Citations (Scopus)

Molecular Cloning of Mouse ERK5/BMK1 Splice Variants and Characterization of ERK5 Functional Domains

Yan, C., Luo, H., Lee, J. D., Abe, J. & Berk, B. C., Apr 6 2001, In : Journal of Biological Chemistry. 276, 14, p. 10870-10878 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 7
Cloning
Molecular Cloning
Complementary DNA
Phosphotransferases
14 Citations (Scopus)

p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells

Che, W., Abe, J. I., Yoshizumi, M., Huang, Q., Glassman, M., Ohta, S., Melaragno, M. G., Poppa, V., Yan, C., Lerner-Marmarosh, N., Zhang, C., Wu, Y., Arlinghaus, R. & Berk, B. C., Sep 18 2001, In : Circulation. 104, 12, p. 1399-1406 8 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor
Extracellular Signal-Regulated MAP Kinases
Vascular Smooth Muscle
Smooth Muscle Myocytes
Phosphotransferases
107 Citations (Scopus)

Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: Comparison with acute mechanical stretch

Takeishi, Y., Huang, Q., Abe, J. I., Glassman, M., Che, W., Lee, J. D., Kawakatsu, H., Lawrence, E. G., Hoit, B. D., Berk, B. C. & Walsh, R. A., Jan 1 2001, In : Journal of Molecular and Cellular Cardiology. 33, 9, p. 1637-1648 12 p.

Research output: Contribution to journalArticle

Cardiomegaly
Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinase 7
Heart Failure
Pressure
42 Citations (Scopus)

Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: Modulation of MAP kinases activation by ischemic preconditioning

Takeishi, Y., Huang, Q., Wang, T., Glassman, M., Yoshizumi, M., Baines, C. P., Lee, J. D., Kawakatsu, H., Che, W., Lerner-Marmarosh, N., Zhang, C., Yan, C., Ohta, S., Walsh, R. A., Berk, B. C. & Abe, J. I., Jan 1 2001, In : Journal of Molecular and Cellular Cardiology. 33, 11, p. 1989-2005 17 p.

Research output: Contribution to journalArticle

Ischemic Preconditioning
src-Family Kinases
Mitogen-Activated Protein Kinases
Adenosine
Myocardium
2000
120 Citations (Scopus)

Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras

Jun-Ichi, A., Okuda, M., Huang, Q., Yoshizumi, M. & Berk, B. C., Jan 21 2000, In : Journal of Biological Chemistry. 275, 3, p. 1739-1748 10 p.

Research output: Contribution to journalArticle

90-kDa Ribosomal Protein S6 Kinases
Reactive Oxygen Species
Chemical activation
Fibroblasts
Signal transduction
98 Citations (Scopus)

Role of mitogen-activated protein kinases in ischemia and reperfusion injury: The good and the bad

Abe, J., Baines, C. P. & Berk, B. C., Mar 31 2000, In : Circulation research. 86, 6, p. 607-609 3 p.

Research output: Contribution to journalEditorial

Myocardial Reperfusion Injury
Mitogen-Activated Protein Kinases
Reperfusion Injury
Cardiac Myocytes
Myocardial Ischemia
229 Citations (Scopus)

Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species

Yoshizumi, M., Abe, J. I., Haendeler, J., Huang, Q. & Berk, B. C., Apr 21 2000, In : Journal of Biological Chemistry. 275, 16, p. 11706-11712 7 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Reactive Oxygen Species
Phosphotransferases
Chemical activation
Mitogen-Activated Protein Kinase 3
1999
74 Citations (Scopus)

Differential regulation of p90 ribosomal S6 kinase and big mitogen- activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts

Takeishi, Y., Abe, J., Lee, J. D., Kawakatsu, H., Walsh, R. A. & Berk, B. C., Dec 3 1999, In : Circulation research. 85, 12, p. 1164-1172 9 p.

Research output: Contribution to journalArticle

90-kDa Ribosomal Protein S6 Kinases
MAP Kinase Kinase 1
Mitogen-Activated Protein Kinase 1
Reperfusion
Guinea Pigs
178 Citations (Scopus)

Fyn and JAK2 mediate Ras activation by reactive oxygen species

Abe, J. & Berk, B. C., Jul 23 1999, In : Journal of Biological Chemistry. 274, 30, p. 21003-21010 8 p.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Chemical activation
Extracellular Signal-Regulated MAP Kinases
Fibroblasts
Transgenic Mice
5 Citations (Scopus)

Inhibitory effects of trapidil on PDGF signaling in balloon-injured rat carotid artery

Deguchi, J. O., Abe, J., Makuuchi, M. & Takuwa, Y., Nov 19 1999, In : Life Sciences. 65, 26, p. 2791-2799 9 p.

Research output: Contribution to journalArticle

Trapidil
Balloons
Platelet-Derived Growth Factor
Carotid Arteries
Rats
198 Citations (Scopus)

p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1

Takáhashi, E., Abe, J., Gallis, B., Aebersold, R., Spring, D. J., Krebs, E. G. & Berk, B. C., Jul 16 1999, In : Journal of Biological Chemistry. 274, 29, p. 20206-20214 9 p.

Research output: Contribution to journalArticle

90-kDa Ribosomal Protein S6 Kinases
Sodium-Hydrogen Antiporter
Phosphorylation
Serine
Protein Isoforms
42 Citations (Scopus)

Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injury

Deguchi, J., Namba, T., Hamada, H., Nakaoka, T., Abe, J., Sato, O., Miyata, T., Makuuchi, M., Kurokawa, K. & Takuwa, Y., Jun 1 1999, In : Gene Therapy. 6, 6, p. 956-965 10 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-sis
Adenoviridae
Smooth Muscle
Wounds and Injuries
Platelet-Derived Growth Factor Receptors
1998
127 Citations (Scopus)

p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells effects on Na+/H+ exchange and ERK1/2

Kusuhara, M., Takahashi, E., Peterson, T. E., Abe, J., Ishida, M., Han, J., Ulevitch, R. & Berk, B. C., Oct 19 1998, In : Circulation Research. 83, 8, p. 824-831 8 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Vascular Smooth Muscle
Angiotensin II
Smooth Muscle Myocytes
234 Citations (Scopus)

Reactive oxygen species as mediators of signal transduction in cardiovascular disease

Abe, J. & Berk, B. C., Feb 1 1998, In : Trends in Cardiovascular Medicine. 8, 2, p. 59-64 6 p.

Research output: Contribution to journalReview article

Reactive Oxygen Species
Signal Transduction
Cardiovascular Diseases
Chemical Phenomena
Biological Phenomena
15 Citations (Scopus)

Tyrosine phosphorylation of platelet derived growth factor β receptors in coronary artery lesions: Implications for vascular remodelling after directional coronary atherectomy and unstable angina pectoris

Abe, J., Deguchi, J., Takuwa, Y., Hara, K., Ikari, Y., Tamura, T., Ohno, M. & Kurokawa, K., Jan 1 1998, In : Heart. 79, 4, p. 400-406 7 p.

Research output: Contribution to journalArticle

Coronary Atherectomy
Platelet-Derived Growth Factor Receptors
Unstable Angina
Tyrosine
Coronary Vessels
1997
46 Citations (Scopus)

Angiotensin II stimulates p90(rsk) in vascular smooth muscle cells: A potential Na+-H+ exchanger kinase

Takahashi, E., Abe, J. & Berk, B. C., Jan 1 1997, In : Circulation Research. 81, 2, p. 268-273 6 p.

Research output: Contribution to journalArticle

90-kDa Ribosomal Protein S6 Kinases
Sodium-Hydrogen Antiporter
Vascular Smooth Muscle
Angiotensin II
Smooth Muscle Myocytes

Angiotensin II Stimulates p90rsk2 in vascular smooth muscle cells: A potential Na+/H+ exchanger kinase

Takahashi, E., Abe, J. I. & Berk, B. C., Dec 1 1997, In : FASEB Journal. 11, 3, p. A500

Research output: Contribution to journalArticle

Sodium-Hydrogen Antiporter
Vascular Smooth Muscle
Angiotensin II
Smooth Muscle Myocytes
Muscle
246 Citations (Scopus)

c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 (BMK1)

Abe, J., Takahashi, M., Ishida, M., Lee, J. D. & Berk, B. C., Aug 15 1997, In : Journal of Biological Chemistry. 272, 33, p. 20389-20394 6 p.

Research output: Contribution to journalArticle

Oxidative stress
Mitogen-Activated Protein Kinase 1
Oxidative Stress
Chemical activation
src-Family Kinases
53 Citations (Scopus)

Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: A link between angiotensin II and intimal thickening

Abe, J., Deguchi, J. O., Matsumoto, T., Takuwa, N., Noda, M., Ohno, M., Makuuchi, M., Kurokawa, K. & Takuwa, Y., Jan 1 1997, In : Circulation. 96, 6, p. 1906-1913 8 p.

Research output: Contribution to journalArticle

Tunica Intima
Platelet-Derived Growth Factor Receptors
Angiotensin II
Platelet-Derived Growth Factor
Arteries
1996
363 Citations (Scopus)

Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase

Abe, J., Kusuhara, M., Ulevitch, R. J., Berk, B. C. & Lee, J. D., Jul 30 1996, In : Journal of Biological Chemistry. 271, 28, p. 16586-16590 5 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 1
Oxidation-Reduction
Phosphotransferases
Mitogen-Activated Protein Kinases
Chemical activation
9 Citations (Scopus)

Thrombotic occlusion of the coronary artery associated with accidental detachment of undeployed Palmaz-Schatz stent

Shiojima, I., Ikari, Y., Abe, J., Ishizaka, N., Maemura, K., Kurihara, H., Isshiki, T. A., Suma, H., Saeki, H., Hara, K., Tamura, T. & Yamaguchi, T., Aug 1 1996, In : Catheterization and Cardiovascular Diagnosis. 38, 4, p. 360-362 3 p.

Research output: Contribution to journalArticle

Stents
Coronary Vessels
Coronary Occlusion
Therapeutics
1994
145 Citations (Scopus)
Retinoblastoma Genes
Angiogenesis Inhibitors
Cyclin-Dependent Kinases
Endothelial Cells
Phosphorylation
49 Citations (Scopus)

Angiographic follow-up after successful percutaneous coronary angioplasty for chronic total coronary occlusion: Experience in 110 consecutive patients

Ishizaka, N., Issiki, T., Saeki, F., Ishizaka, Y., Ikari, Y., Abe, J., Soumitsu, Y., Hashimoto, H., Masaki, K. & Yamaguchi, T., Jan 1 1994, In : American Heart Journal. 127, 1, p. 8-12 5 p.

Research output: Contribution to journalArticle

Coronary Balloon Angioplasty
Coronary Occlusion
Angioplasty
Angiography
Coronary Artery Disease
100 Citations (Scopus)

Suppression of neointimal smooth muscle cell accumulation in vivo by antisense cdc2 and cdk2 oligonucleotides in rat carotid artery

Abe, J., Zhou, W., Taguchi, J. I., Takuwa, N., Miki, K., Okazaki, H., Kurokawa, K., Kumada, M. & Takuwa, Y., Jan 15 1994, In : Biochemical and biophysical research communications. 198, 1, p. 16-24 9 p.

Research output: Contribution to journalArticle

Tunica Intima
Carotid Arteries
Oligonucleotides
Smooth Muscle Myocytes
Muscle
11 Citations (Scopus)

Topical application of AT1 receptor antagonists prevents medial and neointimal proliferation after balloon injury

Taguchi, J., Abe, J., Ohno, M., Schwartz, S. M. & Kurokawa, K., 1994, In : Blood Pressure, Supplement. 3, 5, p. 38-42 5 p.

Research output: Contribution to journalArticle

Neointima
UCON 50-HB-5100
Angiotensin II
Arginine
Wounds and Injuries
1993
25 Citations (Scopus)

Angiotensin converting enzyme inhibitors or DuP753 prevent neointimal formation following balloon injury with single topical or multiple systemic application

Taguchi, J., Abe, J., Okazaki, H., Ochiai, M., Ohno, M., Takuwa, Y. & Kurokawa, K., Oct 29 1993, In : Biochemical and biophysical research communications. 196, 2, p. 969-974 6 p.

Research output: Contribution to journalArticle

Balloons
Angiotensin-Converting Enzyme Inhibitors
UCON 50-HB-5100
Angiotensin II
Wounds and Injuries
46 Citations (Scopus)

L-arginine inhibits neointimal formation following balloon injury

Taguchi, J., Abe, J., Okazaki, H., Takuwa, Y. & Kurokawa, K., Jan 1 1993, In : Life Sciences. 53, 23

Research output: Contribution to journalArticle

Balloons
Arginine
Nitric Oxide
Wounds and Injuries
Blood pressure
14 Citations (Scopus)

Myocardial reperfusion can be predicted by myoglobin/creatine kinase ratio of a single blood sample obtained at the time of admission

Abe, J., Yamaguchi, T., Isshiki, T., Naka, H., Taguchi, J., Ishizaka, N., Kurokawa, K., Saeki, F., Ishizaka, Y., Ui, K., Ikari, Y., Somitsu, Y., Hashimoto, H. & Kashida, M., Jan 1 1993, In : American Heart Journal. 126, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion
Myoglobin
Creatine Kinase
Myocardial Infarction
Reperfusion
1992
2 Citations (Scopus)

Neuronal Hyaline Inclusions Observed in an Autopsy Case of Behçet's Disease

Iihara, K., Abe, J. & Murakami, T., Jan 1 1992, In : Pathology International. 42, 6, p. 432-439 8 p.

Research output: Contribution to journalArticle

Hyalin
Lewy Bodies
Autopsy
Parkinson Disease
Oral Ulcer
1991
1 Citation (Scopus)

Rapid quantitation of serum myoglobin by latex agglutination turbidimetry

Abe, J., Yamaguchi, T., Isshiki, T., Naka, H., Kawada, Y. & Katayama, Y., Nov 9 1991, In : Clinica Chimica Acta. 203, 1, p. 95-96 2 p.

Research output: Contribution to journalLetter

Latex Fixation Tests
Nephelometry and Turbidimetry
Myoglobin
Agglutination
Latex