• 6767 Bertner Ave, Mitchell Basic Science Research Building

    77030 Houston

    United States

  • 23579 Citations
  • 80 h-Index
1993 …2019
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Fingerprint Dive into the research topics where Junjie Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 21 Similar Profiles
DNA Damage Medicine & Life Sciences
Proteins Medicine & Life Sciences
DNA Chemical Compounds
Genomic Instability Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
Repair Chemical Compounds
Neoplasms Medicine & Life Sciences
DNA Replication Medicine & Life Sciences

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Research Output 1993 2019

4 Citations (Scopus)

Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition

Wang, C., Wang, G., Feng, X., Shepherd, P., Zhang, J., Tang, M., Chen, Z., Srivastava, M., McLaughlin, M. E., Navone, N. M., Hart, G. T. & Chen, J., Apr 4 2019, In : Oncogene. 38, 14, p. 2451-2463 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Genome
Prostate
Adenocarcinoma
Ataxia Telangiectasia
1 Citation (Scopus)

Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics

Chen, Z., Lei, C., Wang, C., Li, N., Srivastava, M., Tang, M., Zhang, H., Choi, J. M., Jung, S. Y., Qin, J. & Chen, J., Jan 10 2019, In : Nature communications. 10, 1, 1 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
adenosine monophosphate
AMP-Activated Protein Kinases
proteins
Substrates
1 Citation (Scopus)

Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2

Huang, J., Zhang, J., Bellani, M. A., Pokharel, D., Gichimu, J., James, R. C., Gali, H., Ling, C., Yan, Z., Xu, D., Chen, J., Meetei, A. R., Li, L., Wang, W. & Seidman, M. M., May 7 2019, In : Cell Reports. 27, 6, p. 1794-1808.e5

Research output: Contribution to journalArticle

Open Access
Multicarrier modulation
Fanconi Anemia Complementation Group Proteins
DNA
GTP-Binding Proteins
Proteins

Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling

Li, N., Wang, Y., Neri, S., Zhen, Y., Fong, L. W. R., Qiao, Y., Li, X., Chen, Z., Stephan, C., Deng, W., Ye, R., Jiang, W., Zhang, S., Yu, Y., Hung, M. C., Chen, J. & Lin, S. H., Dec 1 2019, In : Nature communications. 10, 1, 4363.

Research output: Contribution to journalArticle

Open Access
Tankyrases
homeostasis
AMP-Activated Protein Kinases
metabolic diseases
Carcinogenesis
34 Citations (Scopus)

BAP1 links metabolic regulation of ferroptosis to tumour suppression

Zhang, Y., Shi, J., Liu, X., Feng, L., Gong, Z., Koppula, P., Sirohi, K., Li, X., Wei, Y., Lee, H., Zhuang, L., Chen, G., Xiao, Z-D., Hung, M-C., Chen, J., Huang, P., Li, W. & Gan, B., Oct 1 2018, In : Nature cell biology. 20, 10, p. 1181-1192 12 p.

Research output: Contribution to journalArticle

BRCA1 Protein
Neoplasms
Cystine
Ubiquitination
Epigenomics