• 834 Citations
  • 12 h-Index
20022018
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Fingerprint Dive into the research topics where Lei Nie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 27 Similar Profiles
Ubiquitination Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Proteins Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences

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Research Output 2002 2018

  • 834 Citations
  • 12 h-Index
  • 16 Article
  • 1 Review article
11 Citations (Scopus)

EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer

Yamaguchi, H., Du, Y., Nakai, K., Ding, M., Chang, S-S., Hsu, J. L., Yao, J., Wei, Y., Nie, L., Jiao, S., Chang, W-C., Chen, C. H., Yu, Y., Hortobagyi, G. N. & Hung, M-C., Jan 11 2018, In : Oncogene. 37, 2, p. 208-217 10 p.

Research output: Contribution to journalArticle

Poly(ADP-ribose) Polymerases
Adenosine Diphosphate
Breast Neoplasms
Ovarian Neoplasms
DNA Damage
4 Citations (Scopus)

Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer

Lee, P-C., Fang, Y. F., Yamaguchi, H., Wang, W. J., Chen, T. C., Hong, X., Ke, B., Xia, W., Wei, Y., Zha, Z., Wang, Y., Kuo, H. P., Wang, C. W., Tu, C-Y., Chen, C. H., Huang, W-C., Chiang, S. F., Nie, L., Hou, J., Chen, C. T. & 15 others, Huo, L., Yang, W-H., Deng, R., Nakai, K., Hsu, Y-H., Chang, S-S., Chiu, T. J., Tang, J., Zhang, R., Wang, L., Fang, B., Chen, T., Wong, K. K., Hsu, J. L. & Hung, M-C., Dec 10 2018, In : Cancer Cell. 34, 6, p. 954-969.e4

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Protein Kinase C
Lung Neoplasms
Nuclear Proteins
12 Citations (Scopus)

EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway

Zhang, F., Xiang, S., Cao, Y., Li, M., Ma, Q., Liang, H., Li, H., Ye, Y., Zhang, Y., Jiang, L., Hu, Y., Zhou, J., Wang, X., Zhang, Y., Nie, L., Liang, X., Gong, W. & Liu, Y., Jun 8 2017, In : Cell death & disease. 8, 6, p. e2868

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Phosphatidylinositol 3-Kinases
Phosphotransferases
Cell Proliferation
Neoplasm Metastasis
11 Citations (Scopus)

GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers

Ko, H. W., Lee, H-H., Huo, L., Xia, W., Yang, C. C., Hsu, J. L., Li, L-Y., Lai, C. C., Chan, L. C., Cheng, C-C., Labaff, A. M., Liao, H. W., Lim, S-O., Li, C-W., Wei, Y., Nie, L., Yamaguchi, H. & Hung, M-C., Jan 1 2016, In : Oncotarget. 7, 35, p. 57131-57144 14 p.

Research output: Contribution to journalArticle

Methylation
Breast Neoplasms
Cell Movement
Carcinogenesis
Phosphorylation

Phosphorylation of ezh2 at t416 by cdk2 contributes to the malignancy of triple negative breast cancers

Yang, C. C., Labaff, A., Wei, Y., Nie, L., Xia, W., Huo, L., Yamaguchi, H., Hsu, Y-H., Hsu, J. L., Liu, D., Lang, J., Du, Y., Lien, H. C., Li, L-Y., Deng, R., Chan, L. C., Yao, J., Kleer, C. G., Hortobagyi, G. N. & Hung, M-C., Feb 25 2015, In : American Journal of Translational Research. 7, 6, p. 1009-1020 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Cyclin E
Phosphorylation
Chemotherapy
Biomarkers