Makoto Mark Taketo

  • 36385 Citations
  • 105 h-Index
1973 …2019
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Fingerprint Dive into the research topics where Makoto Mark Taketo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Catenins Medicine & Life Sciences
Knockout Mice Medicine & Life Sciences
Genes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Wnt Signaling Pathway Medicine & Life Sciences
Intestinal Polyps Medicine & Life Sciences
Adenomatous Polyposis Coli Medicine & Life Sciences

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Research Output 1973 2019

Arid1a is essential for intestinal stem cells through Sox9 regulation

Hiramatsu, Y., Fukuda, A., Ogawa, S., Goto, N., Ikuta, K., Tsuda, M., Matsumoto, Y., Kimura, Y., Yoshioka, T., Takada, Y., Maruno, T., Hanyu, Y., Tsuruyama, T., Wang, Z., Akiyama, H., Takaishi, S., Miyoshi, H., Taketo, M. M., Chiba, T. & Seno, H., Jan 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1704-1713 10 p.

Research output: Contribution to journalArticle

Stem Cells
Homeostasis
Wnt Receptors
Epithelial Cells
Maintenance

Constitutive activation of β-catenin in conventional dendritic cells increases the insulin reserve to ameliorate the development of type 2 diabetes in mice

MacDougall, C. E., Wood, E. G., Solomou, A., Scagliotti, V., Taketo, M. M., Gaston-Massuet, C., Marelli-Berg, F. M., Charalambous, M. & Longhi, M. P., Jan 1 2019, In : Diabetes. 68, 7, p. 1473-1484 12 p.

Research output: Contribution to journalArticle

Catenins
Dendritic Cells
Type 2 Diabetes Mellitus
Insulin
Obesity
1 Citation (Scopus)

Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate

Wegner, K. A., Mehta, V., Johansson, J. A., Mueller, B. R., Keil, K. P., Abler, L. L., Marker, P. C., Taketo, M. M., Headon, D. J. & Vezina, C. M., Jan 1 2019, In : Biology Open. 8, 3, bio037945.

Research output: Contribution to journalArticle

Open Access
Ectodysplasin Receptors
beta Catenin
collagen
Prostate
Collagen
1 Citation (Scopus)

Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells

Goto, N., Fukuda, A., Yamaga, Y., Yoshikawa, T., Maruno, T., Maekawa, H., Inamoto, S., Kawada, K., Sakai, Y., Miyoshi, H., Taketo, M. M., Chiba, T. & Seno, H., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 26, p. 12996-13005 10 p.

Research output: Contribution to journalArticle

Open Access
Neoplastic Stem Cells
Colorectal Neoplasms
Neoplasms
Interleukin-13
Cell Differentiation

Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice

Benz, F., Wichitnaowarat, V., Lehmann, M., Germano, R. F., Mihova, D., Macas, J., Adams, R. H., Taketo, M. M., Plate, K. H., Guérit, S., Vanhollebeke, B. & Liebner, S., Apr 1 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Subfornical Organ
Catenins
Endothelial cells
Claudin-5
Homeostasis