• 1112 Citations
  • 16 h-Index
20002018
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Research Output 2000 2018

2018

Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53

Høland, M., Kolberg, M., Danielsen, S. A., Bjerkehagen, B., Eilertsen, I. A., Hektoen, M., Mandahl, N., van den Berg, E., Smeland, S., Mertens, F., Sundby Hall, K., Picci, P., Sveen, A. & Lothe, R. A., Nov 1 2018, In : Modern Pathology. 31, 11, p. 1694-1707 14 p.

Research output: Contribution to journalArticle

Neurilemmoma
Survival
Loss of Heterozygosity
p53 Genes
Phenotype
8 Citations (Scopus)

Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer

Bruun, J., Sveen, A., Barros, R., Eide, P. W., Eilertsen, I., Kolberg, M., Pellinen, T., David, L., Svindland, A., Kallioniemi, O., Guren, M. G., Nesbakken, A., Almeida, R. & Lothe, R. A., Sep 2018, In : Molecular oncology. 12, 9, p. 1639-1655 17 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Colorectal Neoplasms
Drug Therapy
Adjuvant Chemotherapy
Survival
2017
4 Citations (Scopus)

Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors

Kolberg, M., Bruun, J., Murumägi, A., Mpindi, J. P., Bergsland, C. H., Høland, M., Eilertsen, I. A., Danielsen, S. A., Kallioniemi, O. & Lothe, R. A., Sep 2017, In : Molecular oncology. 11, 9, p. 1156-1171 16 p.

Research output: Contribution to journalArticle

gemcitabine
Neurilemmoma
Drug Resistance
Pharmaceutical Preparations
Schwann Cells
2015
18 Citations (Scopus)

Connexins in colorectal cancer pathogenesis

Sirnes, S., Lind, G. E., Bruun, J., Fykerud, T. A., Mesnil, M., Lothe, R., Rivedal, E., Kolberg, M. & Leithe, E., Jul 1 2015, In : International Journal of Cancer. 137, 1, p. 1-11 11 p.

Research output: Contribution to journalReview article

Connexins
Colorectal Neoplasms
Connexin 43
Gap Junctions
Cell Membrane
7 Citations (Scopus)

Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis

Danielsen, S. A., Lind, G. E., Kolberg, M., Høland, M., Bjerkehagen, B., Hall, K. S., Van Den Berg, E., Mertens, F., Smeland, S., Picci, P. & Lothe, R., Jan 1 2015, In : Neuro-oncology. 17, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Neurilemmoma
Methylation
Neurofibroma
Tumor Suppressor Genes
11 Citations (Scopus)

Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours - A prognostic test after surgical resection

Kolberg, M., Høland, M., Lind, G. E., Ågesen, T. H., Skotheim, R. I., Hall, K. S., Mandahl, N., Smeland, S., Mertens, F., Davidson, B. & Lothe, R., Jan 1 2015, In : Molecular Oncology. 9, 6, p. 1129-1139 11 p.

Research output: Contribution to journalArticle

Neurilemmoma
Proteins
Neurofibroma
Neurofibromatosis 1
Pharmaceutical Preparations
15 Citations (Scopus)

Regulator of chromosome condensation 2 identifies high-risk patients within both major phenotypes of colorectal cancer

Bruun, J., Kolberg, M., Ahlquist, T. C., Røyrvik, E. C., Nome, T., Leithe, E., Lind, G. E., Merok, M. A., Rognum, T. O., Bjørkøy, G., Johansen, T., Lindblom, A., Sun, X. F., Svindland, A., Liestøl, K., Nesbakken, A., Skotheim, R. I. & Lothe, R., Jan 1 2015, In : Clinical Cancer Research. 21, 16, p. 3759-3770 12 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 2
Microsatellite Repeats
Colorectal Neoplasms
Phenotype
Neoplasms
2014
43 Citations (Scopus)

Prognostic significance of β-catenin, E-cadherin, and SOX9 in colorectal cancer: Results from a large population-representative series

Bruun, J., Kolberg, M., Nesland, J. M., Svindland, A., Nesbakken, A. & Lothe, R. A., Jan 1 2014, In : Frontiers in Oncology. 4 MAY, 118.

Research output: Contribution to journalArticle

Catenins
Cadherins
Colorectal Neoplasms
Population
Proteins
2013
6 Citations (Scopus)

Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin

Lobert, V. H., Bruun, J., Abrahamsen, H., Lothe, R., Stenmark, H. A., Kolberg, M. & Campsteijn, C., Jan 1 2013, In : EMBO reports. 14, 1, p. 10-11 2 p.

Research output: Contribution to journalEditorial

Phosphoprotein Phosphatases
beta Catenin
Nuclear Proteins
Gene expression
Mass spectrometry
104 Citations (Scopus)

Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1

Kolberg, M., Høland, M., Agesen, T. H., Brekke, H. R., Liestøl, K., Hall, K. S., Mertens, F., Picci, P., Smeland, S. & Lothe, R. A., Feb 1 2013, In : Neuro-oncology. 15, 2, p. 135-147 13 p.

Research output: Contribution to journalReview article

Neurofibromatosis 1
Neurilemmoma
Survival Analysis
Meta-Analysis
Survival
2012
66 Citations (Scopus)

Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome

Sirnes, S., Bruun, J., Kolberg, M., Kjenseth, A., Lind, G. E., Svindland, A., Brech, A., Nesbakken, A., Lothe, R., Leithe, E. & Rivedal, E., Aug 1 2012, In : International Journal of Cancer. 131, 3, p. 570-581 12 p.

Research output: Contribution to journalArticle

Connexin 43
Colorectal Neoplasms
Survival
Colonic Neoplasms
Catenins
7 Citations (Scopus)

Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate

Sandvik, G. K., Tomter, A. B., Bergan, J., Zoppellaro, G., Barra, A. L., Røhr, Å. K., Kolberg, M., Ellefsen, S., Andersson, K. K. & Nilsson, G. E., Aug 14 2012, In : PloS one. 7, 8, e42784.

Research output: Contribution to journalArticle

Carassius
ribonucleotide reductase
Ribonucleotide Reductases
Carps
Vertebrates
39 Citations (Scopus)

The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation

Kjenseth, A., Fykerud, T. A., Sirnes, S., Bruun, J., Yohannes, Z., Kolberg, M., Omori, Y., Rivedal, E. & Leithe, E., May 4 2012, In : Journal of Biological Chemistry. 287, 19, p. 15851-15861 11 p.

Research output: Contribution to journalArticle

Sumoylation
Connexin 43
Connexins
Gap Junctions
Ubiquitin
2011
19 Citations (Scopus)

Peritoneal carcinomatosis of colon cancer origin: Highest incidence in women and in patients with right-sided tumors

Sjo, O. H., Berg, M., Merok, M. A., Kolberg, M., Svindland, A., Lothe, R. A. & Nesbakken, A., Dec 1 2011, In : Journal of surgical oncology. 104, 7, p. 792-797 6 p.

Research output: Contribution to journalArticle

Patient Rights
Colonic Neoplasms
Carcinoma
Incidence
Neoplasms
2010
35 Citations (Scopus)

Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group

Brekke, H. R., Ribeiro, F. R., Kolberg, M., Ågesen, T. H., Lind, G. E., Eknæs, M., Hall, K. S., Bjerkehagen, B., Van Den Berg, E., Teixeira, M. R., Mandahl, N., Smeland, S., Mertens, F., Skotheim, R. I. & Lothe, R., Mar 20 2010, In : Journal of Clinical Oncology. 28, 9, p. 1573-1582 10 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 10
Neurilemmoma
DNA Copy Number Variations
Survival
2009
29 Citations (Scopus)

Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors

Brekke, H. R., Kolberg, M., Skotheim, R. I., Hall, K. S., Bjerkehagen, B., Risberg, B., Domanski, H. A., Mandahl, N., Liestøl, K., Smeland, S., Danielsen, H., Mertens, F. & Lothe, R., Oct 1 2009, In : Neuro-oncology. 11, 5, p. 514-528 15 p.

Research output: Contribution to journalArticle

Neurilemmoma
Survival
Cell Cycle Proteins
Neurofibromatosis 1
Biomarkers
2008
37 Citations (Scopus)

Hypermethylated MAL gene - A silent marker of early colon tumorigenesis

Lind, G. E., Ahlquist, T., Kolberg, M., Berg, M., Eknæs, M., Alonso, M. A., Kallioniemi, A., Meling, G. I., Skotheim, R. I., Rognum, T. O., Thiis-Evensen, E. & Lothe, R. A., Mar 17 2008, In : Journal of translational medicine. 6, 13.

Research output: Contribution to journalArticle

Methylation
Colon
Carcinogenesis
Mucous Membrane
Genes
2005
14 Citations (Scopus)

A comparative reactivity study of microperoxidases based on hemin, mesohemin and deuterohemin

Ryabova, E. S., Rydberg, P., Kolberg, M., Harbitz, E., Barra, A. L., Ryde, U., Andersson, K. K. & Nordlander, E., Mar 2005, In : Journal of Inorganic Biochemistry. 99, 3, p. 852-863 12 p.

Research output: Contribution to journalArticle

diglycyl-histidine
Hemin
Esters
Peroxidase
Metmyoglobin
11 Citations (Scopus)

A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H: Combined x-ray diffraction and EPR/ENDOR studies

Kolberg, M., Logan, D. T., Bleifuss, G., Pötsch, S., Sjöberg, B. M., Gräslund, A., Lubitz, W., Lassmann, G. & Lendzian, F., Mar 25 2005, In : Journal of Biological Chemistry. 280, 12, p. 11233-11246 14 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Electron Spin Resonance Spectroscopy
Escherichia coli
Paramagnetic resonance
Iron
12 Citations (Scopus)

The active site residue tyrosine 325 influences iron binding and coupling efficiency in human phenylalanine hydroxylase

Miranda, F. F., Kolberg, M., Andersson, K. K., Geraldes, C. F. G. C. & Martínez, A., Jun 1 2005, In : Journal of Inorganic Biochemistry. 99, 6, p. 1320-1328 9 p.

Research output: Contribution to journalArticle

Phenylalanine Hydroxylase
Tyrosine
Catalytic Domain
Iron
Enzymes
2004
49 Citations (Scopus)

Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse

Strand, K. R., Karlsen, S., Kolberg, M., Røhr, Å. K., Görbitz, C. H. & Andersson, K. K., Nov 5 2004, In : Journal of Biological Chemistry. 279, 45, p. 46794-46801 8 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Iron
Crystals
Proteins
Escherichia coli

Erratum: The use of multi-frequency EPR techniques to identify the radicals produced in irradiated #-blockers, (Free Radical Research vol. 38 (1) (59-66))

Engalytcheff, A., Kolberg, M., Barra, A. L., Andersson, K. K. & Tilquin, B., Mar 1 2004, In : Free Radical Research. 38, 3, p. xxx

Research output: Contribution to journalComment/debate

Free Radicals
Paramagnetic resonance
Research
278 Citations (Scopus)

Structure, function, and mechanism of ribonucleotide reductases

Kolberg, M., Strand, K. R., Graff, P. & Andersson, K. K., Jun 1 2004, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1699, 1-2, p. 1-34 34 p.

Research output: Contribution to journalReview article

Ribonucleotide Reductases
Proteins
Ribonucleotides
Cysteine
Metals
12 Citations (Scopus)

The use of multi-frequency EPR techniques to identify the radicals produced in irradiated β-blockers

Engalytcheff, A., Kolberg, M., Barra, A. L., Andersson, K. K. & Tilquin, B., Jan 1 2004, In : Free Radical Research. 38, 1, p. 59-66 8 p.

Research output: Contribution to journalReview article

Electron Spin Resonance Spectroscopy
Atenolol
Paramagnetic resonance
Nadolol
Propranolol
2003
125 Citations (Scopus)

Displacement of the tyrosyl radical cofactor in ribonucleotide reductase obtained by single-crystal high-field EPR and 1.4-Å x-ray data

Högbom, M., Galander, M., Andersson, M., Kolberg, M., Hofbauer, W., Lassmann, G., Nordlund, P. & Lendzian, F., Mar 18 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 6, p. 3209-3214 6 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
X-Rays
Proteins
Ribonucleotides
Crystallography
30 Citations (Scopus)

Protein thiyl radicals in disordered systems: A comparative epr study at low temperature

Lassmann, G., Kolberg, M., Bleifuss, G., Gräslund, A., Sjöberg, B. M. & Lubitz, W., Jun 1 2003, In : Physical Chemistry Chemical Physics. 5, 11, p. 2442-2453 12 p.

Research output: Contribution to journalArticle

proteins
Cysteine
Bovine Serum Albumin
Proteins
Temperature
2002
17 Citations (Scopus)

Generation and electron paramagnetic resonance spin trapping detection of thiyl radicals in model proteins and in the R1 subunit of Escherichia coli ribonucleotide reductase

Kolberg, M., Bleifuss, G., Sjöberg, B. M., Gräslund, A., Lubitz, W., Lendzian, F. & Lassmann, G., Jan 1 2002, In : Archives of Biochemistry and Biophysics. 397, 1, p. 57-68 12 p.

Research output: Contribution to journalArticle

Spin Trapping
Ribonucleotide Reductases
Photolysis
Electron Spin Resonance Spectroscopy
Escherichia coli
22 Citations (Scopus)

Protein thiyl radicals directly observed by EPR spectroscopy

Kolberg, M., Bleifuss, G., Gräslund, A., Sjöberg, B. M., Lubitz, W., Lendzian, F. & Lassmann, G., Jul 1 2002, In : Archives of Biochemistry and Biophysics. 403, 1, p. 141-144 4 p.

Research output: Contribution to journalArticle

2001
84 Citations (Scopus)

Tryptophan and tyrosine radicals in ribonucleotide reductase: A comparative high-field EPR study at 94 GHz

Bleifuss, G., Kolberg, M., Pötsch, S., Hofbauer, W., Bittl, R., Lubitz, W., Gräslund, A., Lassmann, G. & Lendzian, F., Dec 18 2001, In : Biochemistry. 40, 50, p. 15362-15368 7 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Tryptophan
Paramagnetic resonance
Free Radicals
Deoxyribodipyrimidine Photo-Lyase
2000
10 Citations (Scopus)

A new stable high-valent diiron center in R2 mutant Y122H of E. coli Ribonucleotide reductase studied by high-field EPR and 57Fe-ENDOR [11]

Kolberg, M., Bleifuss, G., Potsch, S., Graslund, A., Lubitz, W., Lassmann, G. & Lendzian, F., Oct 11 2000, In : Journal of the American Chemical Society. 122, 40, p. 9856-9857 2 p.

Research output: Contribution to journalLetter

Ribonucleotide Reductases
Electron Spin Resonance Spectroscopy
Escherichia coli
Paramagnetic resonance
Oxidoreductases