• 5286 Citations
  • 39 h-Index
1987 …2019
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Research Output 1987 2019

  • 5286 Citations
  • 39 h-Index
  • 107 Article
  • 7 Review article
  • 5 Comment/debate
  • 1 Conference contribution
2019
3 Citations (Scopus)
Prostatic Neoplasms
Bone
Bone and Bones
Growth
Tumors
3 Citations (Scopus)

ERR1- And PGC1α-associated mitochondrial alterations correlate with pan-cancer disparity in African Americans

Piyarathna, D. W. B., Balasubramanian, A., Arnold, J. M., Lloyd, S. M., Karanam, B., Castro, P., Ittmann, M. M., Putluri, N., Navone, N., Jones, J. A., Yu, W., Sandulache, V. C., Sikora, A. G., Michailidis, G. & Sreekumar, A., Jun 3 2019, In : Journal of Clinical Investigation. 129, 6, p. 2351-2356 6 p.

Research output: Contribution to journalArticle

Open Access
African Americans
Neoplasms
Organized Financing
Mitochondria
Tissue Array Analysis
4 Citations (Scopus)

Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition

Wang, C., Wang, G., Feng, X., Shepherd, P., Zhang, J., Tang, M., Chen, Z., Srivastava, M., McLaughlin, M. E., Navone, N. M., Hart, G. T. & Chen, J., Apr 4 2019, In : Oncogene. 38, 14, p. 2451-2463 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Genome
Prostate
Adenocarcinoma
Ataxia Telangiectasia

Hyaluronic acid-based hydrogels for patient-derived xenograft culture in a high throughput microfluidic plate

Sablatura, L. K., Bircsak, K. M., Shepherd, P., Navone, N. M., Constantinou, P. E., Saleh, A. D. & Harrington, D. A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hyaluronic acid
Hydrogels
Microfluidics
Hyaluronic Acid
Heterografts

Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer

Sinha, K. M., Yarmand, R., Lahiri, S., Lu, Y., Zhang, M., Amra, S., Rizvi, Y., Wan, X., Navone, N. M., Ozpolat, B., Logothetis, C. J., Gagel, R. F. & Huard, J., Jun 20 2019, In : Oncogene. 38, 25, p. 5038-5049 12 p.

Research output: Contribution to journalArticle

Histone Demethylases
Castration
Prostatic Neoplasms
Epigenomics
Genes

Pseudogene Associated Recurrent Gene Fusion in Prostate Cancer

Chakravarthi, B. VSK., Dedigama-Arachchige, P., Carskadon, S., Sundaram, S. K., Li, J., Wu, K. H. H., Chandrashekar, D. S., Peabody, J. O., Stricker, H., Hwang, C., Chitale, D. A., Williamson, S. R., Gupta, N. S., Navone, N. M., Rogers, C., Menon, M., Varambally, S. & Palanisamy, N., Oct 1 2019, In : Neoplasia (United States). 21, 10, p. 989-1002 14 p.

Research output: Contribution to journalArticle

Open Access
Pseudogenes
Gene Fusion
Prostatic Neoplasms
Urine
African Americans
1 Citation (Scopus)

Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease

Liu, H., He, J., Koh, S. P., Zhong, Y., Liu, Z., Wang, Z., Zhang, Y., Li, Z., Tam, T. K. B., Lin, P., Xiao, M., Young, K. H., Amini, B., Starbuck, M. W., Lee, H. C., Navone, N. M., Davis, R. E., Tong, Q., Bergsagel, P. L., Hou, J. & 4 others, Yi, Q., Orlowski, R., Gagel, R. F. & Yang, J., Jan 1 2019, In : Science Translational Medicine. 11, 494, eaau9087.

Research output: Contribution to journalArticle

Bone Diseases
Adipocytes
Bone Marrow
Peroxisomes
Polycomb Repressive Complex 2
2018
1 Citation (Scopus)

An in vivo screen identifies PYGO2 as a driver for metastatic prostate cancer

Lu, X., Pan, X., Wu, C. J., Zhao, D., Feng, S., Zang, Y., Lee, R., Khadka, S., Amin, S. B., Jin, E. J., Shang, X., Deng, P., Luo, Y., Morgenlander, W. R., Weinrich, J., Lu, X., Jiang, S., Chang, Q., Navone, N. M., Troncoso, P. & 2 others, DePinho, R. A. & Wang, Y. A., Jul 15 2018, In : Cancer research. 78, 14, p. 3823-3833 11 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Oncogenes
Neoplasm Metastasis
Biomarkers
Lymph Nodes
4 Citations (Scopus)

FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer

Pecqueux, C., Arslan, A., Heller, M., Falkenstein, M., Kaczorowski, A., Tolstov, Y., Sültmann, H., Grüllich, C., Herpel, E., Duensing, A., Kristiansen, G., Hohenfellner, M., Navone, N. M. & Duensing, S., Aug 1 2018, In : Urologic Oncology: Seminars and Original Investigations. 36, 8, p. 365.e15-365.e26

Research output: Contribution to journalArticle

Chromosomal Instability
Fibroblast Growth Factor 2
Prostatic Neoplasms
Genomic Instability
Stromal Cells
4 Citations (Scopus)

Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis article

Gueron, G., Anselmino, N., Chiarella, P., Ortiz, E. G., Lage Vickers, S., Paez, A. V., Giudice, J., Contin, M. D., Leonardi, D., Jaworski, F., Manzano, V., Strazza, A., Montagna, D. R., Labanca, E., Cotignola, J., Daccorso, N., Woloszynska-Read, A., Navone, N. M., Meiss, R. P., Ruggiero, R. & 1 others, Vazquez, E., Feb 1 2018, In : Cell Death and Disease. 9, 2, 140.

Research output: Contribution to journalArticle

Phenylalanine
Neoplasm Metastasis
Neoplasms
Prostatic Neoplasms
Tumor Escape
5 Citations (Scopus)

Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone

Dondossola, E., Alexander, S., Holzapfel, B. M., Filippini, S., Starbuck, M. W., Hoffman, R. M., Navone, N. M., De-Juan-pardo, E. M., Logothetis, C. J., Hutmacher, D. W. & Friedl, P., Aug 1 2018, In : Science Translational Medicine. 10, 452, eaao5726.

Research output: Contribution to journalArticle

Bone and Bones
Neoplasms
Osteolysis
Osteoclasts
Therapeutics
7 Citations (Scopus)

Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models

Navone, N. M., van Weerden, W. M., Vessella, R. L., Williams, E. D., Wang, Y., Isaacs, J. T., Nguyen, H. M., Culig, Z., van der Pluijm, G., Rentsch, C. A., Marques, R. B., de Ridder, C. M. A., Bubendorf, L., Thalmann, G. N., Brennen, W. N., Santer, F. R., Moser, P. L., Shepherd, P., Efstathiou, E., Xue, H. & 11 others, Lin, D., Buijs, J., Bosse, T., Collins, A., Maitland, N., Buzza, M., Kouspou, M., Achtman, A., Taylor, R. A., Risbridger, G. & Corey, E., Dec 1 2018, In : Prostate. 78, 16, p. 1262-1282 21 p.

Research output: Contribution to journalArticle

Heterografts
Prostatic Neoplasms
Fluorescence In Situ Hybridization
Androgens
Prostate
9 Citations (Scopus)

Targeting the MYCN–PARP–DNA damage response pathway in neuroendocrine prostate cancer

Zhang, W., Liu, B., Wu, W., Li, L., Broom, B. M., Basourakos, S. P., Korentzelos, D., Luan, Y., Wang, J., Yang, G., Park, S., Azad, A. K., Cao, X., Kim, J., Corn, P., Logothetis, C. J., Aparicio, A., Chinnaiyan, A. M., Navone, N. M., Troncoso, P. & 1 others, Thompson, T., Feb 1 2018, In : Clinical Cancer Research. 24, 3, p. 696-707 12 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Castration
Gene Knockdown Techniques
Aurora Kinase A
Genes

The estrogen receptor variants β2 and β5 induce stem cell characteristics and chemotherapy resistance in prostate cancer through activation of hypoxic signaling

Faria, M., Shepherd, P., Pan, Y., Chatterjee, S. S., Navone, N. M., Gustafsson, J. Å. & Strom, A., Nov 1 2018, In : Oncotarget. 9, 91, p. 36273-36288 16 p.

Research output: Contribution to journalArticle

Estrogen Receptor beta
Prostatic Neoplasms
Stem Cells
Drug Therapy
Neoplastic Stem Cells
2017
2 Citations (Scopus)

In vivo hemin conditioning targets the vascular and immunologic compartments and restrains prostate tumor development

Jaworski, F. M., Gentilini, L. D., Gueron, G., Meiss, R. P., Ortiz, E. G., Berguer, P. M., Ahmed, A., Navone, N. M., Rabinovich, G. A., Compagno, D., Laderach, D. J. & Vazquez, E. S., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5135-5148 14 p.

Research output: Contribution to journalArticle

Hemin
Blood Vessels
Prostate
Heme Oxygenase-1
Neoplasms
56 Citations (Scopus)

Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer

Zhao, D., Lu, X., Wang, G., Lan, Z., Liao, W., Li, J., Liang, X., Chen, J. R., Shah, S., Shang, X., Tang, M., Deng, P., Dey, P., Chakravarti, D., Chen, P., Spring, D. J., Navone, N. M., Troncoso, P., Zhang, J., Wang, Y. A. & 1 others, DePinho, R. A., Feb 23 2017, In : Nature. 542, 7642, p. 484-488 5 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Neoplasms
Synthetic Genes
Essential Genes
Histone Code
20 Citations (Scopus)

Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling

Karanika, S., Karantanos, T., Li, L., Wang, J., Park, S., Yang, G., Zuo, X., Song, J. H., Maity, S. N., Manyam, G. C., Broom, B. M., Aparicio, A., Gallick, G. E., Troncoso, P., Corn, P., Navone, N. M., Zhang, W., Li, S. & Thompson, T., Feb 21 2017, In : Cell Reports. 18, 8, p. 1970-1981 12 p.

Research output: Contribution to journalArticle

Androgen Receptors
DNA Damage
Prostatic Neoplasms
Cell Cycle
DNA
2016
32 Citations (Scopus)

A 3D in vitro model of patient-derived prostate cancer xenograft for controlled interrogation of in vivo tumor-stromal interactions

Fong, E. L. S., Wan, X., Yang, J., Morgado, M., Mikos, A. G., Harrington, D. A., Navone, N. M. & Farach-Carson, M. C., Jan 1 2016, In : Biomaterials. 77, p. 164-172 9 p.

Research output: Contribution to journalArticle

Heterografts
Tumors
Prostatic Neoplasms
Bone
Neoplasms
68 Citations (Scopus)

BET bromodomain inhibitors enhance efficacy and disrupt resistance to AR antagonists in the treatment of prostate cancer

Asangani, I. A., Wilder-Romans, K., Dommeti, V. L., Krishnamurthy, P. M., Apel, I. J., Escara-Wilke, J., Plymate, S. R., Navone, N. M., Wang, S., Feng, F. Y. & Chinnaiyan, A. M., Apr 1 2016, In : Molecular Cancer Research. 14, 4, p. 324-331 8 p.

Research output: Contribution to journalArticle

Androgen Receptor Antagonists
Castration
Prostatic Neoplasms
Androgen Receptors
Prostate
21 Citations (Scopus)

Differentially methylated genes and androgen receptor re-expression in small cell prostate carcinomas

Kleb, B., Estécio, M. R. H., Zhang, J., Tzelepi, V., Chung, W., Jelinek, J., Navone, N. M., Tahir, S., Marquez, V. E., Issa, J. P., Maity, S. & Aparicio, A., Mar 3 2016, In : Epigenetics. 11, 3, p. 184-193 10 p.

Research output: Contribution to journalArticle

Small Cell Carcinoma
Androgen Receptors
Prostate
Genes
Heterografts
11 Citations (Scopus)

Heme oxygenase-1 in the forefront of a multi-molecular network that governs cell–cell contacts and filopodia-induced zippering in prostate cancer

Paez, A. V., Pallavicini, C., Schuster, F., Valacco, M. P., Giudice, J., Ortiz, E. G., Anselmino, N., Labanca, E., Binaghi, M., Salierno, M., Martí, M. A., Cotignola, J. H., Woloszynska-Read, A., Bruno, L., Levi, V., Navone, N., Vazquez, E. S. & Gueron, G., Jan 1 2016, In : Cell Death and Disease. 7, 12, e2570.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Pseudopodia
Prostatic Neoplasms
Cytoskeleton
Prostate
12 Citations (Scopus)

Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients

Liu, J., You, P., Chen, G., Fu, X., Zeng, X., Wang, C., Huang, Y., An, L., Wan, X., Navone, N. M., Wu, C. L., McKeehan, W. L., Zhang, Z., Zhong, W. & Wang, F., Apr 7 2016, In : Oncogene. 35, 14, p. 1750-1759 10 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Prostatic Neoplasms
Fibroblast Growth Factors
Neoplasms
Angiogenesis Inducing Agents
4 Citations (Scopus)

Mechanistic Support for Combined MET and AR Blockade in Castration-Resistant Prostate Cancer

Qiao, Y., Feng, F. Y., Wang, Y., Cao, X., Han, S., Wilder-Romans, K., Navone, N. M., Logothetis, C. J., Taichman, R. S., Keller, E. T., Palapattu, G. S., Alva, A. S., Smith, D. C., Tomlins, S. A., Chinnaiyan, A. M. & Morgan, T. M., Jan 1 2016, In : Neoplasia. 18, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Castration
Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Computer Simulation
15 Citations (Scopus)

Targeted molecular-genetic imaging and liganddirected therapy in aggressive variant prostate cancer

Ferrara, F., Staquicini, D. I., Driessen, W. H. P., D'Angelo, S., Dobroff, A. S., Barry, M., Lomo, L. C., Staquicini, F. I., Cardó-Vila, M., Soghomonyan, S., Alauddin, M. M., Flores, L. G., Arap, M. A., Lauer, R. C., Mathew, P., Efstathiou, E., Aparicio, A. M., Troncoso, P., Navone, N. M., Logothetis, C. J. & 5 others, Marchiò, S., Gelovani, J. G., Sidman, R. L., Pasqualini, R. & Arap, W., Nov 8 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 45, p. 12786-12791 6 p.

Research output: Contribution to journalArticle

Molecular Imaging
Molecular Biology
Prostatic Neoplasms
Bacteriophages
Dependovirus
2015
5 Citations (Scopus)

Association of HO-1 and BRCA1 is critical for the maintenance of cellular homeostasis in prostate cancer

Labanca, E., De Luca, P., Gueron, G., Paez, A., Moiola, C. P., Massillo, C., Porretti, J., Giudice, J., Zalazar, F., Navone, N. M., Vazquez, E. & De Siervi, A., Nov 1 2015, In : Molecular Cancer Research. 13, 11, p. 1455-1464 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Homeostasis
Maintenance
Doxorubicin
DNA Damage

Erratum: Erratum: Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases (Science Translational Medicine (2015) 7 (287er3))

Wan, X., Corn, P., Yang, J., Palanisamy, N., Starbuck, M. W., Efstathiou, E., Tapia, E. M., Zurita-Saavedra, A., Aparicio, A., Ravoori, M. K., Vazquez, E. S., Robinson, D. R., Wu, Y. M., Cao, X., Iyer, M. K., McKeehan, W., Kundra, V., Wang, F., Troncoso, P., Chinnaiyan, A. M. & 2 others, Logothetis, C. J. & Navone, N. M., May 13 2015, In : Science Translational Medicine. 7, 287

Research output: Contribution to journalComment/debate

Translational Medical Research
Stromal Cells
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
36 Citations (Scopus)

Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation

Liu, Z., Xu, J., He, J., Liu, H., Lin, P., Wan, X., Navone, N. M., Tong, Q., Kwak, L. W., Orlowski, R. & Yang, J., Jan 1 2015, In : Oncotarget. 6, 33, p. 34329-34341 13 p.

Research output: Contribution to journalArticle

Autophagy
Adipocytes
Bone Marrow
Drug Therapy
Adipokines
105 Citations (Scopus)

PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3

Salameh, A., Lee, A. K., Cardó-Vila, M., Nunes, D. N., Efstathiou, E., Staquicini, F. I., Dobroff, A. S., Marchiò, S., Navone, N. M., Hosoya, H., Lauer, R. C., Wen, S., Salmeron, C. C., Hoang, A., Newsham, I., Lima, L. A., Carraro, D. M., Oliviero, S., Kolonin, M. G., Sidman, R. L. & 9 others, Do, K. A., Troncoso, P., Logothetis, C. J., Brentani, R. R., Calin, G. A., Cavenee, W. K., Dias-Neto, E., Pasqualini, R. & Arap, W., Jul 7 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 27, p. 8403-8408 6 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Prostatic Neoplasms
Antigens
RNA Editing
Inosine
27 Citations (Scopus)

Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study

Pasqualini, R., Millikan, R. E., Christianson, D. R., Cardõ-Vila, M., Diessen, W. H. P., Giordano, R. J., Hajitou, A., Hoang, A. G., Wen, S., Barnhart, K. F., Baze, W., Marcott, V. D., Hawke, D. H., Do, K-A., Navone, N. M., Efstathiou, E., Troncoso, P., Lobb, R. R., Logothetis, C. J. & Arap, W., Jul 1 2015, In : Cancer. 121, 14, p. 2411-2421 11 p.

Research output: Contribution to journalArticle

Interleukin-11 Receptors
Prostatic Neoplasms
Neoplasms
Ligands
Blood Vessels
2014
28 Citations (Scopus)

Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells

Gueron, G., Giudice, J., Valacco, P., Paez, A., Elguero, B., Toscani, M., Jaworski, F., Leskow, F. C., Cotignola, J., Marti, M., Binaghi, M., Navone, N. & Vazquez, E., 2014, In : Oncotarget. 5, 12, p. 4087-4102 16 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Adhesives
Prostatic Neoplasms
Catenins
Cadherins
30 Citations (Scopus)

Hydrogel-based 3D model of patient-derived prostate xenograft tumors suitable for drug screening

Fong, E. L. S., Martinez, M., Yang, J., Mikos, A. G., Navone, N. M., Harrington, D. A. & Farach-Carson, M. C., Jul 7 2014, In : Molecular Pharmaceutics. 11, 7, p. 2040-2050 11 p.

Research output: Contribution to journalArticle

Preclinical Drug Evaluations
Hydrogel
Heterografts
Prostate
Prostatic Neoplasms
149 Citations (Scopus)

PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer

Prensner, J. R., Chen, W., Iyer, M. K., Cao, Q., Ma, T., Han, S., Sahu, A., Malik, R., Wilder-Romans, K., Navone, N. M., Logothetis, C. J., Araujo, J. C., Pisters, L. L., Tewari, A. K., Canman, C. E., Knudsen, K. E., Kitabayashi, N., Rubin, M. A., Demichelis, F., Lawrence, T. S. & 2 others, Chinnaiyan, A. M. & Feng, F. Y., Mar 15 2014, In : Cancer research. 74, 6, p. 1651-1660 10 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Homologous Recombination
Double-Stranded DNA Breaks
DNA Repair
Neoplasms
49 Citations (Scopus)

Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases

Wan, X., Corn, P., Yang, J., Palanisamy, N., Starbuck, M. W., Efstathiou, E., Li-Ning Tapia, E. M., Zurita-Saavedra, A., Aparicio, A., Ravoori, M. K., Vazquez, E. S., Robinson, D. R., Wu, Y. M., Cao, X., Iyer, M. K., McKeehan, W., Kundra, V., Wang, F., Troncoso, P., Chinnaiyan, A. M. & 2 others, Logothetis, C. J. & Navone, N. M., Sep 3 2014, In : Science Translational Medicine. 6, 252, 252ra122.

Research output: Contribution to journalArticle

Stromal Cells
Prostatic Neoplasms
Fibroblast Growth Factor Receptors
Bone Neoplasms
Neoplasm Metastasis
38 Citations (Scopus)

Targeting poly(ADP-ribose) polymerase and the c-Myb-regulated DNA damage response pathway in castration-resistant prostate cancer

Li, L., Chang, W., Yang, G., Ren, C., Park, S., Karantanos, T., Karanika, S., Wang, J., Yin, J., Shah, P. K., Takahiro, H., Dobashi, M., Zhang, W., Efstathiou, E., Maity, S. N., Aparicio, A., Li Ning Tapia, E. M., Troncoso, P., Broom, B. M., Xiao, L. & 5 others, Lee, H. S., Lee, J-S., Corn, P., Navone, N. M. & Thompson, T., May 20 2014, In : Science Signaling. 7, 326, ra47.

Research output: Contribution to journalArticle

Poly Adenosine Diphosphate Ribose
Ribose
Diphosphates
Castration
Androgen Receptors
2013

Erratum to Mechanistic rationale for inhibition of poly(ADP-Ribose) polymerase in ETS gene fusion-positive prostate cancer [Cancer Cell, 19 (2011) 664-678]

Brenner, J. C., Ateeq, B., Li, Y., Yocum, A. K., Cao, Q., Asangani, I. A., Patel, S., Wang, X., Liang, H., Yu, J., Palanisamy, N., Siddiqui, J., Yan, W., Cao, X., Mehra, R., Sabolch, A., Basrur, V., Lonigro, R. J., Yang, J., Tomlins, S. A. & 8 others, Maher, C. A., Elenitoba-Johnson, K. S. J., Hussain, M., Navone, N. M., Pienta, K. J., Varambally, S., Feng, F. Y. & Chinnaiyan, A. M., Apr 15 2013, In : Cancer cell. 23, 4, 1 p.

Research output: Contribution to journalComment/debate

Poly(ADP-ribose) Polymerases
Gene Fusion
Prostatic Neoplasms
Neoplasms
7 Citations (Scopus)

Glutathione-S-transferase (GST) polymorphisms are associated with relapse after radical prostatectomy

Cotignola, J., Leonardi, D. B., Shahabi, A., Acuña, A. D., Stern, M. C., Navone, N., Scorticati, C., De Siervi, A., Mazza, O. & Vazquez, E., Mar 1 2013, In : Prostate Cancer and Prostatic Diseases. 16, 1, p. 28-34 7 p.

Research output: Contribution to journalArticle

Prostatectomy
Glutathione Transferase
Prostatic Neoplasms
Recurrence
Proportional Hazards Models
7 Citations (Scopus)

Heme oxygenase-1 (HO-1) expression in prostate cancer cells modulates the oxidative response in bone cells

Ferrando, M., Wan, X., Meiss, R., Yang, J., De Siervi, A., Navone, N. & Vazquez, E., Nov 4 2013, In : PloS one. 8, 11, e80315.

Research output: Contribution to journalArticle

heme oxygenase (biliverdin-producing)
Heme Oxygenase-1
prostatic neoplasms
osteoblasts
Osteoblasts
49 Citations (Scopus)

Targeting fibroblast growth factor pathways in prostate cancer

Corn, P., Wang, F., McKeehan, W. L. & Navone, N. M., Nov 1 2013, In : Clinical Cancer Research. 19, 21, p. 5856-5866 11 p.

Research output: Contribution to journalReview article

Fibroblast Growth Factors
Prostatic Neoplasms
MAP Kinase Kinase 3
Fibroblast Growth Factor Receptors
1-Phosphatidylinositol 4-Kinase
2012
41 Citations (Scopus)

Activation of β-catenin signaling in androgen receptor-negative prostate cancer cells

Wan, X., Liu, J., Lu, J. F., Tzelepi, V., Yang, J., Starbuck, M. W., Diao, L., Wang, J., Efstathiou, E., Vazquez, E. S., Troncoso, P., Maity, S. N. & Navone, N. M., Feb 1 2012, In : Clinical Cancer Research. 18, 3, p. 726-736 11 p.

Research output: Contribution to journalArticle

Catenins
Androgen Receptors
Prostatic Neoplasms
Genes
Bone and Bones
36 Citations (Scopus)

Arachidonic acid metabolism in human prostate cancer

Yang, P., Cartwright, C. A., Li, J., Wen, S., Prokhorova, I. N., Shureiqi, I., Troncoso, P., Navone, N. M., Newman, R. A. & Kim, J., Oct 1 2012, In : International journal of oncology. 41, 4, p. 1495-1503 9 p.

Research output: Contribution to journalArticle

Arachidonic Acid
Prostatic Neoplasms
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
Lipoxygenases
Heterografts
16 Citations (Scopus)

Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma

Yang, J., He, J., Wang, J., Cao, Y., Ling, J., Qian, J., Lu, Y., Li, H., Zheng, Y., Lan, Y., Hong, S., Matthews, J., Starbuck, M. W., Navone, N. M., Orlowski, R. Z., Lin, P., Kwak, L. W. & Yi, Q., Sep 1 2012, In : Leukemia. 26, 9, p. 2114-2123 10 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Multiple Myeloma
Bone and Bones
Neoplasms
SCID Mice
34 Citations (Scopus)

Effect of transforming growth factor beta (TGF-β) receptor I kinase inhibitor on prostate cancer bone growth

Wan, X., Li, Z. G., Yingling, J. M., Yang, J., Starbuck, M. W., Ravoori, M. K., Kundra, V., Vazquez, E. & Navone, N. M., Mar 1 2012, In : Bone. 50, 3, p. 695-703 9 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Bone Development
Prostatic Neoplasms
Phosphotransferases
Osteoblasts
23 Citations (Scopus)

Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b

Karlou, M., Lu, J. F., Wu, G., Maity, S., Tzelepi, V., Navone, N. M., Hoang, A., Logothetis, C. J. & Efstathiou, E., Nov 1 2012, In : Prostate. 72, 15, p. 1638-1647 10 p.

Research output: Contribution to journalArticle

HhAntag691
Hedgehogs
Heterografts
Prostatic Neoplasms
Bone and Bones
33 Citations (Scopus)

Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer

Sircar, K., Huang, H., Hu, L., Cogdell, D., Dhillon, J., Tzelepi, V., Efstathiou, E., Koumakpayi, I. H., Saad, F., Luo, D., Bismar, T. A., Aparicio, A., Troncoso, P., Navone, N. M. & Zhang, W., Mar 1 2012, In : American Journal of Pathology. 180, 3, p. 895-903 9 p.

Research output: Contribution to journalArticle

Aspartate-Ammonia Ligase
Castration
Prostatic Neoplasms
Asparagine
Heterografts
11 Citations (Scopus)

Mitosis phase enrichment with identification of mitotic centromere-associated kinesin as a therapeutic target in castration-resistant prostate cancer

Sircar, K., Huang, H., Hu, L., Liu, Y., Dhillon, J., Cogdell, D., Aprikian, A., Efstathiou, E., Navone, N. M., Troncoso, P. & Zhang, W., Feb 17 2012, In : PLoS One. 7, 2, e31259.

Research output: Contribution to journalArticle

Kinesin
kinesin
Centromere
Castration
centromeres
69 Citations (Scopus)

Modeling a lethal prostate cancer variant with small-cell carcinoma features

Tzelepi, V., Zhang, J., Lu, J. F., Kleb, B., Wu, G., Wan, X., Hoang, A., Efstathiou, E., Sircar, K., Navone, N. M., Troncoso, P., Liang, S., Logothetis, C. J., Maity, S. N. & Aparicio, A., Feb 1 2012, In : Clinical Cancer Research. 18, 3, p. 666-677 12 p.

Research output: Contribution to journalArticle

Small Cell Carcinoma
Heterografts
Prostate
Prostatic Neoplasms
Neuroendocrine Carcinoma
24 Citations (Scopus)

Unveiling the association of STAT3 and HO-1 in prostate cancer: Role beyond heme degradation

Elguero, B., Gueron, G., Giudice, J., Toscani, M. A., de Luca, P., Zalazar, F., Coluccio-Leskow, F., Meiss, R., Navone, N. M., de Siervi, A. & Vazquez, E., Jan 1 2012, In : Neoplasia (United States). 14, 11, p. 1043-1056 14 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Heme Oxygenase-1
Heme
Prostatic Neoplasms
Androgen Receptors
2 Citations (Scopus)

Vascular patterning and permeability in prostate cancer models with differing osteogenic properties

Dafni, H., Burghardt, A. J., Majumdar, S., Navone, N. M. & Ronen, S. M., Jun 1 2012, In : NMR in Biomedicine. 25, 6, p. 843-851 9 p.

Research output: Contribution to journalArticle

Capillary Permeability
Prostatic Neoplasms
Bone and Bones
Pericytes
Neoplasm Metastasis
2011
32 Citations (Scopus)

Androgen regulation of 5α-Reductase isoenzymes in prostate cancer: Implications for prostate cancer prevention

Li, J., Ding, Z., Wang, Z., Lu, J. F., Maity, S. N., Navone, N. M., Logothetis, C. J., Mills, G. B. & Kim, J., Dec 14 2011, In : PLoS One. 6, 12, e28840.

Research output: Contribution to journalArticle

prostatic neoplasms
androgens
Androgens
Isoenzymes
isozymes
52 Citations (Scopus)

Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer

Ferrando, M., Gueron, G., Elguero, B., Giudice, J., Salles, A., Leskow, F. C., Jares-Erijman, E. A., Colombo, L., Meiss, R., Navone, N. M., De Siervi, A. & Vazquez, E., Dec 1 2011, In : Angiogenesis. 14, 4, p. 467-479 13 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Prostatic Neoplasms
Switches
Neoplasms
Tumors