Research output per year
Research output per year
- 11 results
Search results
-
2022
ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer
Hsieh, R. C. E., Krishnan, S., Wu, R. C., Boda, A. R., Liu, A., Winkler, M., Hsu, W. H., Lin, S. H., Hung, M. C., Chan, L. C., Bhanu, K. R., Srinivasamani, A., De Azevedo, R. A., Chou, Y. C., DePinho, R. A., Gubin, M., Vilar, E., Chen, C. H., Slay, R., Jayaprakash, P., & 14 others, May 2022, In: Science Immunology. 7, 72, eabl9330.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Hypoxia Reduction Sensitizes Refractory Cancers to Immunotherapy
Jayaprakash, P., Vignali, P. D. A., Delgoffe, G. M. & Curran, M. A., 2022, In: Annual Review of Medicine. 73, p. 251-265 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access28 Scopus citations -
2021
A Phase I dose-escalation study to evaluate the safety and tolerability of evofosfamide in combination with ipilimumab in advanced solid malignancies
Hegde, A., Jayaprakash, P., Couillault, C. A., Piha-Paul, S., Karp, D., Rodon, J., Pant, S., Fu, S., Dumbrava, E. E., Yap, T. A., Subbiah, V., Bhosale, P., Coarfa, C., Higgins, J. P., Williams, E. T., Wilson, T. F., Lim, J. A., Meric-Bernstam, F., Sumner, E., Zain, H., & 5 others, Jun 1 2021, In: Clinical Cancer Research. 27, 11, p. 3050-3060 11 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
High potency STING agonists engage unique myeloid pathways to reverse pancreatic cancer immune privilege
Ager, C. R., Boda, A., Rajapakshe, K., Lea, S. T., DI Francesco, M. E., Jayaprakash, P., Slay, R. B., Morrow, B., Prasad, R., Dean, M. A., Duffy, C. R., Coarfa, C., Jones, P. & Curran, M. A., Aug 2 2021, In: Journal for immunotherapy of cancer. 9, 8, 003246.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
2020
Melanoma evolves complete immunotherapy resistance through the acquisition of a hypermetabolic phenotype
Jaiswal, A. R., Liu, A. J., Pudakalakatti, S., Dutta, P., Jayaprakash, P., Bartkowiak, T., Ager, C. R., Wang, Z. Q., Reuben, A., Cooper, Z. A., Ivan, C., Ju, Z., Nwajei, F., Wang, J., Davies, M. A., Eric Davis, R., Wargo, J. A., Bhattacharya, P. K., Hong, D. S. & Curran, M. A., Nov 1 2020, In: Cancer Immunology Research. 8, 11, p. 1365-1380 16 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
2018
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy
Jayaprakash, P., Ai, M., Liu, A., Budhani, P., Bartkowiak, T., Sheng, J., Ager, C., Nicholas, C., Jaiswal, A. R., Sun, Y., Shah, K., Balasubramanyam, S., Li, N., Wang, G., Ning, J., Zal, A., Zal, T. & Curran, M. A., Nov 1 2018, In: Journal of Clinical Investigation. 128, 11, p. 5137-5149 13 p.Research output: Contribution to journal › Article › peer-review
Open Access257 Scopus citations -
2017
Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression
Zou, M., Bhatia, A., Dong, H., Jayaprakash, P., Guo, J., Sahu, D., Hou, Y., Tsen, F., Tong, C., O'Brien, K., Situ, A. J., Schmidt, T., Chen, M., Ying, Q., Ulmer, T. S., Woodley, D. T. & Li, W., Apr 1 2017, In: Oncogene. 36, 15, p. 2160-2171 12 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
PRAS40 connects microenvironmental stress signaling to exosome-mediated secretion
Guo, J., Jayaprakash, P., Dan, J., Wise, P., Jang, G. B., Liang, C., Chen, M., Woodley, D. T., Fabbri, M. & Li, W., Oct 1 2017, In: Molecular and cellular biology. 37, 19, e00171-17.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
2016
Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment
Dong, H., Zou, M., Bhatia, A., Jayaprakash, P., Hofman, F., Ying, Q., Chen, M., Woodley, D. T. & Li, W., Feb 5 2016, In: Scientific reports. 6, 20605.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
2015
Hsp90α and Hsp90β together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing
Jayaprakash, P., Dong, H., Zou, M., Bhatia, A., O'Brien, K., Chen, M., Woodley, D. T. & Li, W., 2015, In: Journal of cell science. 128, 8, p. 1475-1480 6 p.Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations -
2012
The anti-motility signaling mechanism of TGFβ3 that controls cell traffic during skin wound healing
Han, A., Bandyopadhyay, B., Jayaprakash, P., Lua, I., Sahu, D., Chen, M., Woodley, D. T. & Li, W., Dec 15 2012, In: Biology Open. 1, 12, p. 1169-1177 9 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations