Research output per year
Research output per year
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Dive into the research topics where Quanyun Xu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials
Yap, T. A., Daver, N., Mahendra, M., Zhang, J., Kamiya-Matsuoka, C., Meric-Bernstam, F., Kantarjian, H. M., Ravandi, F., Collins, M. E., Francesco, M. E. D., Dumbrava, E. E., Fu, S., Gao, S., Gay, J. P., Gera, S., Han, J., Hong, D. S., Jabbour, E. J., Ju, Z. & Karp, D. D. & 29 others, , Jan 2023, In: Nature medicine. 29, 1, p. 115-126 12 p.Research output: Contribution to journal › Article › peer-review
Open Access118 Scopus citations -
Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy
Le, K., Soth, M. J., Cross, J. B., Liu, G., Ray, W. J., Ma, J., Goodwani, S. G., Acton, P. J., Buggia-Prevot, V., Akkermans, O., Barker, J., Conner, M. L., Jiang, Y., Liu, Z., McEwan, P., Warner-Schmidt, J., Xu, A., Zebisch, M., Heijnen, C. J. & Abrahams, B. & 1 others, , Jul 27 2023, In: Journal of Medicinal Chemistry. 66, 14, p. 9954-9971 18 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme
Hamilton, M. M., Mseeh, F., McAfoos, T. J., Leonard, P. G., Reyna, N. J., Harris, A. L., Xu, A., Han, M., Soth, M. J., Czako, B., Theroff, J. P., Mandal, P. K., Burke, J. P., Virgin-Downey, B., Petrocchi, A., Pfaffinger, D., Rogers, N. E., Parker, C. A., Yu, S. S. & Jiang, Y. & 10 others, , Aug 12 2021, In: Journal of Medicinal Chemistry. 64, 15, p. 11302-11329 28 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties
Soth, M. J., Le, K., Di Francesco, M. E., Hamilton, M. M., Liu, G., Burke, J. P., Carroll, C. L., Kovacs, J. J., Bardenhagen, J. P., Bristow, C. A., Cardozo, M., Czako, B., De Stanchina, E., Feng, N., Garvey, J. R., Gay, J. P., Do, M. K. G., Greer, J., Han, M. & Harris, A. & 27 others, , Nov 12 2020, In: Journal of Medicinal Chemistry. 63, 21, p. 12957-12977 21 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Scopus citations -
An inhibitor of oxidative phosphorylation exploits cancer vulnerability
Molina, J. R., Sun, Y., Protopopova, M., Gera, S., Bandi, M., Bristow, C., McAfoos, T., Morlacchi, P., Ackroyd, J., Agip, A. N. A., Al-Atrash, G., Asara, J., Bardenhagen, J., Carrillo, C. C., Carroll, C., Chang, E., Ciurea, S., Cross, J. B., Czako, B. & Deem, A. & 46 others, , Jul 1 2018, In: Nature medicine. 24, 7, p. 1036-1046 11 p.Research output: Contribution to journal › Article › peer-review
630 Scopus citations