Richard Julian Jones

Assistant Professor

  • 674 Citations
  • 15 h-Index
19982019
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  • 4 Similar Profiles
Multiple Myeloma Medicine & Life Sciences
Human Herpesvirus 4 Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Epstein-Barr Virus Infections Medicine & Life Sciences
Mantle-Cell Lymphoma Medicine & Life Sciences
Autophagy Medicine & Life Sciences

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Research Output 1998 2019

  • 674 Citations
  • 15 h-Index
  • 26 Article
  • 1 Comment/debate
  • 1 Editorial
3 Citations (Scopus)

Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma

Zhuang, J., Shirazi, F., Singh, R. K., Kuiatse, I., Wang, H., Lee, H. C., Berkova, Z., Berger, A., Hyer, M., Chattopadhyay, N., Syed, S., Shi, J. Q., Yu, J., Shinde, V., Tirrell, S., Jones, R. J., Wang, Z., Davis, R. E. & Orlowski, R., Apr 4 2019, In : Blood. 133, 14, p. 1572-1584 13 p.

Research output: Contribution to journalArticle

Ubiquitin-Activating Enzymes
Enzyme inhibition
Unfolded Protein Response
Drug Resistance
Endoplasmic Reticulum Stress
14 Citations (Scopus)

Protein targeting chimeric molecules specific for bromodomain and extra-terminal motif family proteins are active against pre-clinical models of multiple myeloma

Zhang, X., Lee, H. C., Shirazi, F., Baladandayuthapani, V., Lin, H., Kuiatse, I., Wang, H., Jones, R. J., Berkova, Z., Singh, R. K., Lu, J., Qian, Y., Raina, K., Coleman, K. G., Crews, C. M., Li, B., Wang, H., Hailemichael, Y., Thomas, S. K., Wang, Z. & 2 others, Davis, R. E. & Orlowski, R. Z., Oct 1 2018, In : Leukemia. 32, 10, p. 2224-2239 16 p.

Research output: Contribution to journalArticle

Amino Acid Motifs
Protein Transport
Multiple Myeloma
Dexamethasone
Ubiquitination
1 Citation (Scopus)

Targeting myddosome signaling in Waldenstrom's macroglobulinemia with the interleukin-1 receptor-associated kinase 1/4 inhibitor R191

Ni, H., Shirazi, F., Baladandayuthapani, V., Lin, H., Kuiatse, I., Wang, H., Jones, R. J., Berkova, Z., Hitoshi, Y., Ansell, S. M., Treon, S. P., Thomas, S. K., Lee, H. C., Wang, Z., Davis, R. E. & Orlowski, R., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6408-6420 13 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptor-Associated Kinases
Waldenstrom Macroglobulinemia
NF-kappa B
Cell Line
Cyclin-Dependent Kinase 6
5 Citations (Scopus)

Chondroitin sulfate proteoglycan serglycin influences protein cargo loading and functions of tumor-derived exosomes

Purushothaman, A., Bandari, S. K., Chandrashekar, D. S., Jones, R. J., Lee, H. C., Weber, D. M. & Orlowski, R. Z., Jan 1 2017, In : Oncotarget. 8, 43, p. 73723-73732 10 p.

Research output: Contribution to journalArticle

Exosomes
Chondroitin Sulfate Proteoglycans
Neoplasms
Proteins
serglycin

Exosome targeted therapy-a step in the future

Gingras, M. C. & Jones, R. J., Dec 1 2017, In : Translational Cancer Research. 6, p. S1398-S1401

Research output: Contribution to journalEditorial

Exosomes
Therapeutics