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Research Output 1984 2020

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Comment/debate
2019
1 Citation (Scopus)

Corrigendum: Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome (Genes & Development, (2004) 18, (1533-1538))

Corradetti, M. N., Inoki, K., Bardeesy, N., DePinho, R. A. & Guan, K. L., Apr 1 2019, In : Genes and Development. 33, 7-8, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Peutz-Jeghers Syndrome
Tuberous Sclerosis
Starvation
Glucose
Genes

Erratum: Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer (Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer (2014) 158(1) (185–197), (S0092867414007247), (10.1016/j.cell.2014.06.003))

Kapoor, A., Yao, W., Ying, H., Hua, S., Liewen, A., Wang, Q., Zhong, Y., Wu, C. J., Sadanandam, A., Hu, B., Chang, Q., Chu, G. C., Al-Khalil, R., Jiang, S., Xia, H., Fletcher-Sananikone, E., Lim, C., Horwitz, G. I., Viale, A., Pettazzoni, P. & 10 others, Sanchez, N., Wang, H., Protopopov, A., Zhang, J., Heffernan, T., Johnson, R. L., Chin, L., Wang, Y. A., Draetta, G. & DePinho, R. A., Nov 14 2019, In : Cell. 179, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
United States Office of Research Integrity
Somatostatin-Secreting Cells
Pancreatic Neoplasms
Chemical activation
2018
18 Citations (Scopus)

Erratum: Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment (Cancer Cell (2017) 32(1) (42–56.e6)(S1535610817302532)(10.1016/j.ccell.2017.06.003))

Wang, Q., Hu, B., Hu, X., Kim, H., Squatrito, M., Scarpace, L., deCarvalho, A. C., Lyu, S., Li, P., Li, Y., Barthel, F., Cho, H. J., Lin, Y. H., Satani, N., Martinez-Ledesma, E., Zheng, S., Chang, E., Gabriel Sauvé, C. E., Olar, A., Lan, Z. D. & 14 others, Finocchiaro, G., Phillips, J. J., Berger, M. S., Gabrusiewicz, K. R., Wang, G., Eskilsson, E., Hu, J., Mikkelsen, T., DePinho, R. A., Muller, F., Heimberger, A. B., Sulman, E. P., Nam, D. H. & Verhaak, R. G. W., Jan 8 2018, In : Cancer cell. 33, 1, 1 p.

Research output: Contribution to journalComment/debate

Cellular Microenvironment
Tumor Microenvironment
Glioma
Gene Expression
Genes
2015

Erratum: Passenger deletions generate therapeutic vulnerabilities in cancer (Nature (2012) 488 (337-342) DOI:10.1038/nature11331)

Muller, F., Colla, S., Aquilanti, E., Manzo, V. E., Genovese, G., Lee, J., Eisenson, D., Narurkar, R., Deng, P., Nezi, L., Lee, M., Hu, B., Hu, J., Sahin, E., Ong, D., Fletcher-Sananikone, E., Ho, D., Kwong, L., Brennan, C., Wang, Y. A. & 2 others, Chin, L. & Depinho, R. A., Sep 10 2015, In : Nature. 525, 7568, 1 p.

Research output: Contribution to journalComment/debate

Neoplasms
Therapeutics
1 Citation (Scopus)

Erratum: FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization (Nature Communications 6 (7079) DOI: 10.1038/ncomms8079)

O-Sullivan, I., Zhang, W., Wasserman, D. H., Liew, C. W., Liu, J., Paik, J., Depinho, R. A., Stolz, D. B., Kahn, C. R., Schwartz, M. W. & Unterman, T. G., Jul 24 2015, In : Nature communications. 6, 8861.

Research output: Contribution to journalComment/debate

Insulin
Glucose
Communication
2014
1 Citation (Scopus)

Erratum: Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1 (Cell Metabolism (2013) 17 (901-915))

Kajimura, D., Lee, H. W., Riley, K. J., Arteaga-Solis, E., Ferron, M., Zhou, B., Clarke, C. J., Hannun, Y. A., DePinho, R. A., Guo, X. E., Mann, J. J. & Karsenty, G., May 6 2014, In : Cell Metabolism. 19, 5, 1 p.

Research output: Contribution to journalComment/debate

Adiponectin
Bone and Bones
2013

Erratum: Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway (Nature (2013) 496 (101-105) DOI: 10.1038/nature12040)

Son, J., Lyssiotis, C. A., Ying, H., Wang, X., Hua, S., Ligorio, M., Perera, R. M., Ferrone, C. R., Mullarky, E., Ng, S. C., Kang, Y., Fleming, J. B., Bardeesy, N., Asara, J. M., Haigis, M. C., Depinho, R. A., Cantley, L. C. & Kimmelman, A. C., Jun 17 2013, In : Nature. 499, 7459, 1 p.

Research output: Contribution to journalComment/debate

Metabolic Networks and Pathways
Glutamine
Pancreatic Neoplasms
Growth
2012
193 Citations (Scopus)

Axis of ageing: Telomeres, p53 and mitochondria

Sahin, E. & DePinho, R. A., Jun 1 2012, In : Nature Reviews Molecular Cell Biology. 13, 6, p. 397-404 8 p.

Research output: Contribution to journalComment/debate

Telomere
DNA Damage
Mitochondria
Organelle Biogenesis
Therapeutics
2011

Erratum: Telomere dysfunction induces metabolic and mitochondrial compromise (Nature (2011) 470 (359-365))

Sahin, E., Colla, S., Liesa, M., Moslehi, J., Müller, F. L., Guo, M., Cooper, M., Kotton, D., Fabian, A. J., Walkey, C., Maser, R. S., Tonon, G., Foerster, F., Xiong, R., Wang, Y. A., Shukla, S. A., Jaskelioff, M., Martin, E. S., Heffernan, T. P., Protopopov, A. & 10 others, Ivanova, E., Mahoney, J. E., Kost-Alimova, M., Perry, S. R., Bronson, R., Liao, R., Mulligan, R., Shirihai, O. S., Chin, L. & Depinho, R. A., Jul 14 2011, In : Nature. 475, 7355, 1 p.

Research output: Contribution to journalComment/debate

Telomere
2 Citations (Scopus)

Erratum: AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias (Cell (2011) 146 (697-708))

Sykes, S. M., Lane, S. W., Bullinger, L., Kalaitzidis, D., Yusuf, R., Saez, B., Ferraro, F., Mercier, F., Singh, H., Brumme, K. M., Acharya, S. S., Scholl, C., Tothova, Z., Attar, E. C., Fröhling, S., DePinho, R. A., Gilliland, D. G., Armstrong, S. A. & Scadden, D. T., Sep 30 2011, In : Cell. 147, 1, 1 p.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)

Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

Scott, K. L., Nogueira, C., Heffernan, T. P., van Doorn, R., Dhakal, S., Hanna, J. A., Min, C., Jaskelioff, M., Xiao, Y., Wu, C. J., Cameron, L. A., Perry, S. R., Zeid, R., Feinberg, T., Kim, M., Vande Woude, G., Granter, S. R., Bosenberg, M., Chu, G. C., DePinho, R. A. & 2 others, Rimm, D. L. & Chin, L., Aug 16 2011, In : Cancer Cell. 20, 2, 1 p.

Research output: Contribution to journalComment/debate

Oncogenes
Melanoma
Neoplasm Metastasis
2010

Erratum: FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice (Journal of Clinical Investigation (2010) 120, 1 (357-368) (DOI:10.1172/JCI39901))

Rached, M. T., Kode, A., Silva, B. C., Jung, D. Y., Gray, S., Ong, H., Paik, J. H., DePinho, R. A., Kim, J. K., Karsenty, G. & Kousteni, S., Mar 1 2010, In : Journal of Clinical Investigation. 120, 3, 1 p.

Research output: Contribution to journalComment/debate

Osteocalcin
Osteoblasts
Homeostasis
Glucose
53 Citations (Scopus)

Towards patient-based cancer therapeutics

Schreiber, S. L., Shamji, A. F., Clemons, P. A., Hon, C., Koehler, A. N., Munoz, B., Palmer, M., Stern, A. M., Wagner, B. K., Powers, S., Lowe, S. W., Guo, X., Krasnitz, A., Sawey, E. T., Sordella, R., Stein, L., Trotman, L. C., Califano, A., Dalla-Favera, R., Ferrando, A. & 19 others, Iavarone, A., Pasqualucci, L., Silva, J., Stockwell, B. R., Hahn, W. C., Chin, L., DePinho, R. A., Boehm, J. S., Gopal, S., Huang, A., Root, D. E., Weir, B. A., Gerhard, D. S., Zenklusen, J. C., Roth, M. G., White, M. A., Minna, J. D., MacMillan, J. B. & Posner, B. A., Sep 1 2010, In : Nature biotechnology. 28, 9, p. 904-906 3 p.

Research output: Contribution to journalComment/debate

2007

Erratum: Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma (Ecography (2007) 21 (98-111))

Stegh, A. H., Kim, H., Bachoo, R. M., Forloney, K. L., Zhang, J., Schulze, H., Park, K., Hannon, G. J., Yuan, J., Louis, D. N., DePinho, R. A. & Chin, L., Feb 15 2007, In : Genes and Development. 21, 4, 1 p.

Research output: Contribution to journalComment/debate

Glioblastoma
Apoptosis
2006
1 Citation (Scopus)

The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans (DOI:10.1016/j.ccr.2006.03.028)

Carrasco, D. R., Fenton, T., Sukhdeo, K., Protopopova, M., Enos, M., You, M. J., Di Vizio, D., Nogueira, C., Stommel, J., Pinkus, G. S., Fletcher, C., Hornick, J. L., Cavenee, W. K., Furnari, F. B. & DePinho, R. A., Aug 1 2006, In : Cancer cell. 10, 2, 1 p.

Research output: Contribution to journalComment/debate

Histiocytic Sarcoma
Human Development
Homeostasis
Neoplasms
2004
1 Citation (Scopus)

Erratum: Molecular diversity of astrocytes with implications for neurological disorders (Proceedings of the National Academy of Sciencs of the United States of America (June 1, 2004) 101, 22 (8384-8389))

Bachoo, R. M., Kim, R. S., Ligon, K. L., Maher, E. A., Brennan, C., Billings, N., Chan, S., Li, C., Rowitch, D. H., Wong, W. H. & DePinho, R. A., Jul 13 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 28, p. 10494 1 p.

Research output: Contribution to journalComment/debate

2003

Erratum: Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis (Nature Medicine (2002) 8 (1276-1280))

Sharp, R., Recio, J. A., Jhappan, C., Otsuka, T., Liu, S., Yu, Y., Liu, W., Anver, M., Navid, F., Helman, L. J., DePinho, R. A. & Merlino, G., Jan 1 2003, In : Nature medicine. 9, 1, 1 p.

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Erratum: Telomere-based crisis: Functional differences between telomerase activation and alt in tumor progression (Genes and Development (2003) 17 (88-100))

Chang, S., Khoo, C. M., Naylor, M. L., Maser, R. S. & DePinho, R. A., Feb 15 2003, In : Genes and Development. 17, 4, p. 541 1 p.

Research output: Contribution to journalComment/debate

Telomerase
Telomere
Genes
Neoplasms
2002
58 Citations (Scopus)

Telomerase extracurricular activities

Chang, S. & DePinho, R. A., Oct 1 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 20, p. 12520-12522 3 p.

Research output: Contribution to journalComment/debate

Cyclin-Dependent Kinase Inhibitor p16
Proto-Oncogene Proteins p21(ras)
Cultured Tumor Cells
Telomerase
Telomere
1995

Erratum: Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells (Nature Medicine (1995) 1 (638-643))

Chen, J., Willingham, T., Margraf, L. R., Schreiber-Agus, N., DePinho, R. A. & Nisen, P. D., Jan 1 1995, In : Nature medicine. 1, 12, 1 p.

Research output: Contribution to journalComment/debate

Cell proliferation
Medicine
Tumors
Brain
Cells
1991
Glucocorticoids
Signal Transduction
Hormones
Gene Expression