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Research Output 1984 2020

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Short survey
2011
3 Citations (Scopus)

Cancer drug discovery faces the FACT

Draetta, G. & DePinho, R. A., Aug 10 2011, In : Science Translational Medicine. 3, 95, 95ps34.

Research output: Contribution to journalShort survey

Drug Discovery
Chromatin Assembly and Disassembly
Translational Medical Research
Cell Division
Neoplasms
2007
26 Citations (Scopus)

Cancer biology: Gone but not forgotten

Sharpless, N. E. & DePinho, R. A., Feb 8 2007, In : Nature. 445, 7128, p. 606-607 2 p.

Research output: Contribution to journalShort survey

Tumor Suppressor Protein p53
Neoplasms
Therapeutics
2005
117 Citations (Scopus)

Cancer: Crime and punishment

Sharpless, N. E. & DePinho, R. A., Aug 4 2005, In : Nature. 436, 7051, p. 636-637 2 p.

Research output: Contribution to journalShort survey

Punishment
Cell Aging
Crime
Cell Culture Techniques
Growth
9 Citations (Scopus)

How disruption of cell cycle regulating genes might predispose to sun-induced skin cancer

Rünger, T. M., Vergilis, I., Sarkar, P., DePinho, R. A. & Sharpless, N. E., May 2005, In : Cell Cycle. 4, 5, p. 643-645 3 p.

Research output: Contribution to journalShort survey

cdc Genes
Skin Neoplasms
Solar System
Keratinocytes
DNA Repair
24 Citations (Scopus)

PTEN: A novel anti-oncogenic function independent of phosphatase activity

Okumura, K., Zhao, M., DePinho, R. A., Furnari, F. B. & Cavenee, W. K., Apr 2005, In : Cell Cycle. 4, 4, p. 540-542 3 p.

Research output: Contribution to journalShort survey

Phosphoric Monoester Hydrolases
Mutation
Protein Stability
Phosphoprotein Phosphatases
Catalytic Domain
2004
78 Citations (Scopus)

Cancer chromosomes in crisis

DePinho, R. A. & Polyak, K., Sep 1 2004, In : Nature Genetics. 36, 9, p. 932-934 3 p.

Research output: Contribution to journalShort survey

Telomere
Chromosome Aberrations
Chromosomes
Breast Neoplasms
Neoplasms
16 Citations (Scopus)

Conquering the complexity of p53

Attardi, L. D. & DePinho, R. A., Jan 1 2004, In : Nature Genetics. 36, 1, p. 7-8 2 p.

Research output: Contribution to journalShort survey

Neoplastic Gene Expression Regulation
Mutant Strains Mice
p53 Genes
Signal Transduction
Cell Cycle
2002
23 Citations (Scopus)

Keeping telomerase in its place

Maser, R. S. & DePinho, R. A., Sep 1 2002, In : Nature medicine. 8, 9, p. 934-936 3 p.

Research output: Contribution to journalShort survey

Genomic Instability
Telomerase
Ionizing radiation
Ionizing Radiation
Cell Cycle
2001
7 Citations (Scopus)

Cancer: Telomerase meets its mismatch

Kucherlapati, R. & DePinho, R. A., Jun 7 2001, In : Nature. 411, 6838, p. 647-648 2 p.

Research output: Contribution to journalShort survey

Telomerase
Telomere
Neoplasms
Chromosomes
Yeasts
2000
28 Citations (Scopus)

Flipping the oncogene switch: Illumination of tumor maintenance and regression

Chin, L. & DePinho, R. A., Apr 1 2000, In : Trends in Genetics. 16, 4, p. 147-150 4 p.

Research output: Contribution to journalShort survey

Lighting
Oncogenes
Maintenance
Neoplasms
Biological Adaptation
1999
8 Citations (Scopus)

A bumper crop of cancer genes

DePinho, R. A. & Jacks, T., Nov 19 1999, In : Nature Genetics. 23, 3, p. 253-254 2 p.

Research output: Contribution to journalShort survey

Experimental Leukemias
Neoplastic Cell Transformation
Proviruses
Insertional Mutagenesis
Neoplasm Genes
1998
61 Citations (Scopus)

The cancer-chromatin connection

DePinho, R. A., Feb 5 1998, In : Nature. 391, 6667, p. 533-536 4 p.

Research output: Contribution to journalShort survey

Viral Cell Transformation
Genetic Transcription
E2F Transcription Factors
Retinoblastoma Genes
Retinoblastoma Protein