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Sachet Ashok Shukla

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Sachet Ashok Shukla

Assistant Professor

 https://orcid.org/0000-0003-2445-3584
    20112026

    Research activity per year

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    • PKCβ Inhibitor MS-553 Displays Preclinical Efficacy in Both Treatment-Naïve and BTK Inhibitor-Resistant Chronic Lymphocytic Leukemia

      Gordon, B. K., Muhowski, E. M., Singh, J., Ravikrishnan, J., Peris-Cuesta, A., Diaz Rohena, D., Sanchez, J. R., Thangavadivel, S., Benrashid, S., He, A., Marr, A. R., Mitchell, A. D., Urrutia, J. M., Misra, S., Lai, T. H., Yu, L., Walker, B. R., Perry, E., Shukla, S. A. & Grieselhuber, N. R. & 12 others, Rogers, K. A., Lapalombella, R., Blachly, J. S., Kittai, A. S., Bhat, S. A., Jain, N., Wierda, W. G., Byrd, J. C., Niesman, M., Zhang, K., Sampath, D. & Woyach, J. A., Jan 12 2026, In: Blood Cancer Discovery. 7, 1, p. 85-103 19 p.

      Research output: Contribution to journal › Article › peer-review

      1   Link opens in a new tab Scopus citations

    • A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma

      Blass, E., Keskin, D. B., Tu, C. R., Forman, C., Vanasse, A., Sax, H. E., Shim, B., Chea, V., Kim, N., Carulli, I., Southard, J., Lyu, H., Lu, W., Rickles-Young, M., Afeyan, A. B., Olive, O., Mehndiratta, A., Greenslade, H., Shetty, K. & Baginska, J. & 24 others, Gomez Diaz, I., Nau, A., Pfaff, K. L., Gans, A., Ranasinghe, S., Buchbinder, E. I., Sussman, T. A., Insco, M. L., Yoon, C. H., Rodig, S. J., Shukla, S. A., Li, S., Aster, J. C., Braun, D. A., Cibulskis, C., Hacohen, N., Neuberg, D. S., Giobbie-Hurder, A., Livak, K. J., Fritsch, E. F., Oliveira, G., Simon, J. M., Wu, C. J. & Ott, P. A., Sep 18 2025, In: Cell. 188, 19, p. 5125-5141.e27

      Research output: Contribution to journal › Article › peer-review

      Open Access
      24   Link opens in a new tab Scopus citations

    • A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

      Braun, D. A., Moranzoni, G., Chea, V., McGregor, B. A., Blass, E., Tu, C. R., Vanasse, A. P., Forman, C., Forman, J., Afeyan, A. B., Schindler, N. R., Liu, Y., Li, S., Southard, J., Chang, S. L., Hirsch, M. S., LeBoeuf, N. R., Olive, O., Mehndiratta, A. & Greenslade, H. & 30 others, Shetty, K., Klaeger, S., Sarkizova, S., Pedersen, C. B., Mossanen, M., Carulli, I., Tarren, A., Duke-Cohan, J., Howard, A. A., Iorgulescu, J. B., Shim, B., Simon, J. M., Signoretti, S., Aster, J. C., Elagina, L., Carr, S. A., Leshchiner, I., Getz, G., Gabriel, S., Hacohen, N., Olsen, L. R., Oliveira, G., Neuberg, D. S., Livak, K. J., Shukla, S. A., Fritsch, E. F., Wu, C. J., Keskin, D. B., Ott, P. A. & Choueiri, T. K., Mar 13 2025, In: Nature. 639, 8054, p. 474-482 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      165   Link opens in a new tab Scopus citations

    • HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy

      Jiang, Q., Braun, D. A., Clauser, K. R., Ramesh, V., Shirole, N. H., Duke-Cohan, J. E., Nabilsi, N., Kramer, N. J., Forman, C., Lippincott, I. E., Klaeger, S., Phulphagar, K. M., Chea, V., Kim, N., Vanasse, A. P., Saad, E., Parsons, T., Carr-Reynolds, M., Carulli, I. & Pinjusic, K. & 26 others, Jiang, Y., Li, R., Syamala, S., Rachimi, S., Verzani, E. K., Stevens, J. D., Lane, W. J., Camp, S. Y., Meli, K., Pappalardi, M. B., Herbert, Z. T., Qiu, X., Cejas, P., Long, H. W., Shukla, S. A., Van Allen, E. M., Choueiri, T. K., Churchman, L. S., Abelin, J. G., Gurer, C., MacBeath, G., Childs, R. W., Carr, S. A., Keskin, D. B., Wu, C. J. & Kaelin, W. G., Apr 3 2025, In: Cell. 188, 7, p. 1807-1827.e34

      Research output: Contribution to journal › Article › peer-review

      Open Access
      46   Link opens in a new tab Scopus citations

    • Immunogenomic determinants of exceptional response to immune checkpoint inhibition in renal cell carcinoma

      Jammihal, T., Saliby, R. M., Labaki, C., Soulati, H., Gallegos, J., Peris, A., McCurry, D., Yu, C., Shah, V., Poduval, D., El Zarif, T., El Ahmar, N., Laimon, Y. N., Eid, M., Sheshdeh, A. B., Krajewski, K. M., Büttner, F. A., Schwab, M., Heng, D. & Casellas, R. C. & 9 others, Rai, K., Zacharias Millward, N. M., Msaouel, P., Karam, J., Signoretti, S., Van Allen, E., Choueiri, T. K., Braun, D. A. & Shukla, S. A., Feb 2025, In: Nature Cancer. 6, 2, p. 372-384 13 p., e001079.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      29   Link opens in a new tab Scopus citations
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