• 6767 Bertner Ave, Mitchell Basic Science Research Building

    77030 Houston

    United States

  • 11659 Citations
  • 50 h-Index
1979 …2019
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Research Output 1979 2019

2019

Complementary roles of gcn5 and pcaf in foxp3+ t-regulatory cells

Liu, Y., Bao, C., Wang, L., Han, R., Beier, U. H., Akimova, T., Cole, P. A., Dent, S. Y. R. & Hancock, W. W., Apr 2019, In : Cancers. 11, 4, 554.

Research output: Contribution to journalArticle

Open Access
Histone Acetyltransferases
Acetyltransferases
Allografts
p300-CBP Transcription Factors
Proteins

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways

Farria, A. T., Mustachio, L. M., Coban Akdemir, Z. H. & Dent, S. Y. R., Oct 1 2019, In : Oncotarget. 10, 56, p. 5847-5858 12 p.

Research output: Contribution to journalArticle

Burkitt Lymphoma
Cell Survival
Gene Expression
Lymphoma
B-Lymphocytes
5 Citations (Scopus)

TGFb-activated USP27X deubiquitinase regulates cell migration and chemoresistance via stabilization of Snail1

Lambies, G., Miceli, M., Martínez-Guillamon, C., Olivera-Salguero, R., Peña, R., Frías, C. P., Calderon, I., Atanassov, B., Dent, S. R., Arribas, J., García de Herreros, A. & Díaz, V. M., Jan 1 2019, In : Cancer research. 79, 1, p. 33-46 14 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Cell Movement
Tumor Cell Line
Fibroblasts
Epithelial Cells
3 Citations (Scopus)

USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta

Koutelou, E., Wang, L., Schibler, A. C., Chao, H. P., Kuang, X., Lin, K., Lu, Y., Shen, J., Jeter, C. R., Salinger, A., Wilson, M., Chen, Y. C., Atanassov, B. S., Tang, D. G. & Dent, S. Y. R., Feb 2019, In : Development (Cambridge). 146, 4, dev174037.

Research output: Contribution to journalArticle

Open Access
Pericytes
Receptor Protein-Tyrosine Kinases
Embryonic Stem Cells
Cardiovascular System
Placenta
2018
4 Citations (Scopus)

Cross-talk between chromatin acetylation and SUMOylation of tripartite motif–containing protein 24 (TRIM24) impacts cell adhesion

Appikonda, S., Thakkar, K. N., Shah, P. K., Dent, S. Y. R., Andersen, J. N. & Barton, M. C., Jan 1 2018, In : Journal of Biological Chemistry. 293, 19, p. 7476-7485 10 p.

Research output: Contribution to journalArticle

Sumoylation
Acetylation
Cell adhesion
Cell Adhesion
Chromatin
6 Citations (Scopus)

Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice

Bao, J., Perez, C. J., Kim, J., Zhang, H., Murphy, C. J., Hamidi, T., Jaubert, J., Platt, C. D., Chou, J., Deng, M., Zhou, M. H., Huang, Y., Gaitán-Peñas, H., Guénet, J. L., Lin, K., Lu, Y., Chen, T., Bedford, M. T., Dent, S. Y., Richburg, J. H. & 5 others, Estévez, R., Pan, H. L., Geha, R. S., Shi, Q. & Benavides, F., Aug 23 2018, In : JCI Insight. 3, 16

Research output: Contribution to journalArticle

Male Infertility
Germ Cells
Anions
Sertoli Cell-Only Syndrome
Spermatozoa
11 Citations (Scopus)

Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis

Franco, H. L., Nagari, A., Malladi, V. S., Li, W., Xi, Y., Richardson, D., Allton, K. L., Tanaka, K., Li, J., Murakami, S., Keyomarsi, K., Bedford, M. T., Shi, X., Li, W., Barton, M. C., Dent, S. Y. R. & Kraus, W. L., Feb 2018, In : Genome research. 28, 2, p. 159-170 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Gene Expression
Triple Negative Breast Neoplasms
Transcription Factors
Cell Line
6 Citations (Scopus)

GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation

Wang, L., Koutelou, E., Hirsch, C., McCarthy, R., Schibler, A., Lin, K., Lu, Y., Jeter, C., Shen, J., Barton, M. C. & Dent, S. Y. R., Jan 1 2018, In : Stem Cell Reports. 10, 1, p. 287-299 13 p.

Research output: Contribution to journalArticle

Embryoid Bodies
Fibroblast Growth Factors
Genes
Gene expression
Chromatin
4 Citations (Scopus)

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

Xi, Y., Shi, J., Li, W., Tanaka, K., Allton, K. L., Richardson, D., Li, J., Franco, H. L., Nagari, A., Malladi, V. S., Coletta, L. D., Simper, M. S., Keyomarsi, K., Shen, J., Bedford, M. T., Shi, X., Barton, M. C., Lee Kraus, W., Li, W. & Dent, S. Y. R., Feb 20 2018, In : BMC genomics. 19, 1, 150.

Research output: Contribution to journalArticle

Histone Code
Epigenomics
Chromatin
Breast Neoplasms
Cell Line
2017
9 Citations (Scopus)

Diencephalic size is restricted by a novel interplay between GCN5 acetyltransferase activity and retinoic acid signaling

Wilde, J. J., Siegenthaler, J. A., Dent, S. Y. R. & Niswander, L. A., Mar 8 2017, In : Journal of Neuroscience. 37, 10, p. 2565-2579 15 p.

Research output: Contribution to journalArticle

Acetyltransferases
Tretinoin
Response Elements
Prosencephalon
Neuroepithelial Cells
9 Citations (Scopus)

KATapulting toward Pluripotency and Cancer

Hirsch, C. L., Wrana, J. L. & Dent, S. R., Jun 30 2017, In : Journal of Molecular Biology. 429, 13, p. 1958-1977 20 p.

Research output: Contribution to journalReview article

Neoplasms
Chromatin
Transcriptome
Cues
Carcinogenesis
12 Citations (Scopus)

Leucine-rich repeat containing 8A (LRRC8A)–dependent volume-regulated anion channel activity is dispensable for T-cell development and function

Platt, C. D., Chou, J., Houlihan, P., Badran, Y. R., Kumar, L., Bainter, W., Poliani, P. L., Perez, C. J., Dent, S. Y. R., Clapham, D. E., Benavides, F. & Geha, R. S., Dec 2017, In : Journal of Allergy and Clinical Immunology. 140, 6, p. 1651-1659.e1

Research output: Contribution to journalArticle

Leucine
Anions
T-Lymphocytes
B-Lymphocytes
Agammaglobulinemia
5 Citations (Scopus)

Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia

Butler, J. S., Qiu, Y. H., Zhang, N., Yoo, S. Y., Coombes, K. R., Dent, S. R. & Kornblau, S. M., May 4 2017, In : Leukemia and Lymphoma. 58, 5, p. 1207-1218 12 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Proteins
Leukemia
Protein Array Analysis
Cell Adhesion
7 Citations (Scopus)

The histone acetyltransferase Gcn5 positively regulates T Cell activation

Gao, B., Kong, Q., Zhang, Y., Yun, C., Dent, S. Y. R., Song, J., Zhang, D. D., Wang, Y., Li, X. & Fang, D., May 15 2017, In : Journal of Immunology. 198, 10, p. 3927-3938 12 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
T-Lymphocytes
Proteins
Interleukin-2
Autoimmune Experimental Encephalomyelitis
7 Citations (Scopus)

The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation

Wang, Y., Yun, C., Gao, B., Xu, Y., Zhang, Y., Wang, Y., Kong, Q., Zhao, F., Wang, C. R., Dent, S. Y. R., Wang, J., Xu, X., Li, H. B. & Fang, D., Jul 18 2017, In : Cell Reports. 20, 3, p. 600-612 13 p.

Research output: Contribution to journalArticle

Acetylation
Natural Killer T-Cells
Acetyltransferases
T-cells
Lysine
9 Citations (Scopus)

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation

Li, J., Xi, Y., Li, W., McCarthy, R. L., Stratton, S. A., Zou, W., Li, W., Dent, S. Y., Jain, A. K. & Barton, M. C., May 25 2017, In : Oncogene. 36, 21, p. 2991-3001 11 p.

Research output: Contribution to journalArticle

Genes
MCF-7 Cells
Chromatin
Stem Cells
Maintenance
11 Citations (Scopus)

YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer

Mi, W., Guan, H., Lyu, J., Zhao, D., Xi, Y., Jiang, S., Andrews, F. H., Wang, X., Gagea, M., Wen, H., Tora, L., Dent, S. Y. R., Kutateladze, T. G., Li, W., Li, H. & Shi, X., Dec 1 2017, In : Nature communications. 8, 1, 1088.

Research output: Contribution to journalArticle

acetylation
Acetylation
Non-Small Cell Lung Carcinoma
Histones
lungs
2016
34 Citations (Scopus)

ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth

Atanassov, B. S., Mohan, R. D., Lan, X., Kuang, X., Lu, Y., Lin, K., McIvor, E., Li, W., Zhang, Y., Florens, L., Byrum, S. D., Mackintosh, S. G., Calhoun-Davis, T., Koutelou, E., Wang, L., Tang, D. G., Tackett, A. J., Washburn, M. P., Workman, J. L. & Dent, S. Y. R., May 19 2016, In : Molecular cell. 62, 4, p. 558-571 14 p.

Research output: Contribution to journalArticle

Cell Proliferation
Histones
Growth
Neoplasms
Neurodegenerative Diseases
4 Citations (Scopus)

Cytoplasmic ATXN7L3B interferes with nuclear functions of the SAGA deubiquitinase module

Li, W., Atanassov, B. S., Lan, X., Mohan, R. D., Swanson, S. K., Farria, A. T., Florens, L., Washburn, M. P., Workman, J. L. & Dent, S. Y. R., Jan 1 2016, In : Molecular and cellular biology. 36, 22, p. 2855-2866 12 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Histones
Catalytic Domain
Cytoplasm
Deubiquitinating Enzymes
7 Citations (Scopus)

Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2

Schibler, A., Koutelou, E., Tomida, J., Wilson-Pham, M., Wang, L., Lu, Y., Cabrera, A. P., Chosed, R. J., Li, W., Li, B., Shi, X., Wood, R. D. & Dent, S. Y. R., May 15 2016, In : Genes and Development. 30, 10, p. 1187-1197 11 p.

Research output: Contribution to journalArticle

M Phase Cell Cycle Checkpoints
Benomyl
Histones
Methylation
Cdc20 Proteins

Sharon Dent: The unfolding SAGA of chromatin-modifying proteins

Dent, S. & Sedwick, C., Jan 4 2016, In : The Journal of cell biology. 212, 1, p. 4-5 2 p.

Research output: Contribution to journalArticle

p300-CBP Transcription Factors
Protein Unfolding
Chromatin
Proteins
13 Citations (Scopus)

USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B

Lan, X., Atanassov, B., Li, W., Zhang, Y., Florens, L., Mohan, R. D., Galardy, P. J., Washburn, M. P., Workman, J. L. & Dent, S. R., Nov 22 2016, In : Cell Reports. 17, 9, p. 2382-2393 12 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Histones
Genes
Chromatin
Cells
2015
35 Citations (Scopus)

Excision of expanded GAA repeats alleviates the molecular phenotype of friedreich's ataxia

Li, Y., Polak, U., Bhalla, A. D., Rozwadowska, N., Butler, J. S., Lynch, D. R., Dent, S. Y. R. & Napierala, M., Jun 1 2015, In : Molecular Therapy. 23, 6, p. 1055-1065 11 p.

Research output: Contribution to journalArticle

Friedreich Ataxia
Guanine
Adenine
Phenotype
Zinc Fingers
12 Citations (Scopus)

Increased susceptibility to skin carcinogenesis associated with a spontaneous mouse mutation in the palmitoyl transferase Zdhhc13 gene

Perez, C. J., Mecklenburg, L., Jaubert, J., Martinez-Santamaria, L., Iritani, B. M., Espejo, A., Napoli, E., Song, G., Del Río, M., DiGiovanni, J., Giulivi, C., Bedford, M. T., Dent, S. Y. R., Wood, R. D., Kusewitt, D. F., Guénet, J. L., Conti, C. J. & Benavides, F., Dec 1 2015, In : Journal of Investigative Dermatology. 135, 12, p. 3133-3143 11 p.

Research output: Contribution to journalArticle

Zinc Fingers
Transferases
Zinc
Skin
Carcinogenesis
57 Citations (Scopus)

KATs in cancer: Functions and therapies

Farria, A., Li, W. & Dent, S. R., Sep 17 2015, In : Oncogene. 34, 38, p. 4901-4913 13 p.

Research output: Contribution to journalReview article

Acetylation
Neoplasms
Therapeutics
Histone Code
Biological Phenomena
33 Citations (Scopus)

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

Hirsch, C. L., Akdemir, Z. C., Wang, L., Jayakumaran, G., Trcka, D., Weiss, A., Javier Hernandez, J., Pan, Q., Han, H., Xu, X., Xia, Z., Salinger, A. P., Wilson, M., Vizeacoumar, F., Datti, A., Li, W., Cooney, A. J., Barton, M. C., Blencowe, B. J., Wrana, J. L. & 1 others, Dent, S. Y. R., Jan 1 2015, In : Genes and Development. 29, 8, p. 803-816 14 p.

Research output: Contribution to journalArticle

Alternative Splicing
Epigenomics
Histone Acetyltransferases
Gene Regulatory Networks
Embryonic Stem Cells
25 Citations (Scopus)

REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

Tomida, J., Takata, K. I., Lange, S. S., Schibler, A. C., Yousefzadeh, M. J., Bhetawal, S., Dent, S. Y. R. & Wood, R. D., Jan 30 2015, In : Nucleic acids research. 43, 2, p. 1000-1011 12 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
DNA Damage
Binding Sites
Chromosome Breakage
Mutagenesis
2014
135 Citations (Scopus)

AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation

Li, Y., Wen, H., Xi, Y., Tanaka, K., Wang, H., Peng, D., Ren, Y., Jin, Q., Dent, S. R., Li, W., Li, H. & Shi, X., Oct 23 2014, In : Cell. 159, 3, p. 558-571 14 p.

Research output: Contribution to journalArticle

Acetylation
Methylation
Histones
Chromatin
Methyltransferases
293 Citations (Scopus)

Chromatin modifiers and remodellers: Regulators of cellular differentiation

Chen, T. & Dent, S. Y. R., Feb 1 2014, In : Nature Reviews Genetics. 15, 2, p. 93-106 14 p.

Research output: Contribution to journalReview article

Chromatin
Germ Layers
Gastrulation
Adult Stem Cells
Chromatin Assembly and Disassembly
45 Citations (Scopus)

Functions of SAGA in development and disease

Wang, L. & Dent, S. Y. R., Jun 2014, In : Epigenomics. 6, 3, p. 329-339 11 p.

Research output: Contribution to journalReview article

Histone Acetyltransferases
DNA-Binding Proteins
Gene Expression Regulation
Neurodegenerative Diseases
Histones
14 Citations (Scopus)

Gcn 5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1

Jin, Q., Zhuang, L., Lai, B., Wang, C., Li, W., Dolan, B., Lu, Y., Wang, Z., Zhao, K., Peng, W., Dent, S. Y. R. & Ge, K., Nov 1 2014, In : EMBO reports. 15, 11, p. 1192-1201 10 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Interferons
Acetylation
Innate Immunity
Antiviral Agents
20 Citations (Scopus)

Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis

Jin, Q., Wang, C., Kuang, X., Feng, X., Sartorelli, V., Ying, H., Ge, K. & Dent, S. Y. R., Jan 1 2014, In : Molecular and cellular biology. 34, 19, p. 3746-3753 8 p.

Research output: Contribution to journalArticle

Adipogenesis
Peroxisome Proliferator-Activated Receptors
1-Methyl-3-isobutylxanthine
Acetyltransferases
RNA Polymerase II
32 Citations (Scopus)

K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation

Stilling, R. M., Rönicke, R., Benito, E., Urbanke, H., Capece, V., Burkhardt, S., Bahari-Javan, S., Barth, J., Sananbenesi, F., Schütz, A. L., Dyczkowski, J., Martinez-Hernandez, A., Kerimoglu, C., Dent, S. R., Bonn, S., Reymann, K. G. & Fischer, A., Sep 1 2014, In : EMBO Journal. 33, 17, p. 1912-1927 16 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Acetyltransferases
Gene Regulatory Networks
Gene expression
Lysine
2013
47 Citations (Scopus)

Chromatin: Receiver and quarterback for cellular signals

Johnson, D. G. & Dent, S. Y. R., Feb 14 2013, In : Cell. 152, 4, p. 685-689 5 p.

Research output: Contribution to journalReview article

Chromatin
Histones
Histone Code
Signal transduction
Chromosome Segregation
143 Citations (Scopus)

DANPOS: Dynamic analysis of nucleosome position and occupancy by sequencing

Chen, K., Xi, Y., Pan, X., Li, Z., Kaestner, K., Tyler, J., Dent, S., He, X. & Li, W., Feb 1 2013, In : Genome research. 23, 2, p. 341-351 11 p.

Research output: Contribution to journalArticle

Nucleosomes
Nucleotides
Genome
Nucleic Acid Regulatory Sequences
Hematopoietic Stem Cells
11 Citations (Scopus)

Expanded complexity of unstable repeat diseases

Polak, U., Mcivor, E., Dent, S. Y. R., Wells, R. D. & Napierala, M., Mar 1 2013, In : BioFactors. 39, 2, p. 164-175 12 p.

Research output: Contribution to journalReview article

DNA sequences
Gene Expression Profiling
Pathologic Processes
Proteome
Microsatellite Repeats
43 Citations (Scopus)

Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects

Ravnskjaer, K., Hogan, M. F., Lackey, D., Tora, L., Dent, S. Y. R., Olefsky, J. & Montminy, M., Oct 1 2013, In : Journal of Clinical Investigation. 123, 10, p. 4318-4328 11 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Gluconeogenesis
Glucagon
Epigenomics
Fasting
18 Citations (Scopus)

Stabilization of the promoter nucleosomes in nucleosome-free regions by the yeast Cyc8-Tup1 corepressor

Chen, K., Wilson, M. A., Hirsch, C., Watson, A., Liang, S., Lu, Y., Li, W. & Dent, S. Y. R., Feb 1 2013, In : Genome research. 23, 2, p. 312-322 11 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Nucleosomes
Yeasts
Genes
Gene Expression
8 Citations (Scopus)

The lasting influence of LSD1 in the blood

Dent, S. Y. R. & Chandra, J., Jun 18 2013, In : eLife. 2013, 2, e00963.

Research output: Contribution to journalArticle

Histone Demethylases
Blood
26 Citations (Scopus)

The role of chromatin modifiers in normal and malignant hematopoiesis

Butler, J. S. & Dent, S. Y. R., Jan 1 2013, In : Blood. 121, 16, p. 3076-3084 9 p.

Research output: Contribution to journalReview article

Hematopoiesis
Chromatin
Epigenomics
Enzymes
Blood
2012
9 Citations (Scopus)

Chromatin 'resetting' during transcription elongation: A central role for methylated H3K36

Butler, J. S. & Dent, S. R., Sep 1 2012, In : Nature Structural and Molecular Biology. 19, 9, p. 863-864 2 p.

Research output: Contribution to journalArticle

Fungal Gene Expression Regulation
Saccharomyces cerevisiae Proteins
DNA-Binding Proteins
Histones
Chromatin
25 Citations (Scopus)

Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model

Chen, Y. C., Gatchel, J. R., Lewis, R. W., Mao, C. A., Grant, P. A., Zoghbi, H. Y. & Dent, S. Y. R., Jan 1 2012, In : Human molecular genetics. 21, 2, p. 394-405 12 p., ddr474.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Retinal Degeneration
Histone Acetyltransferases
Purkinje Cells
Ataxia
64 Citations (Scopus)

Histone-modifying enzymes: Regulators of developmental decisions and drivers of human disease

Butler, J. S., Koutelou, E., Schibler, A. C. & Dent, S. R., Apr 1 2012, In : Epigenomics. 4, 2, p. 163-177 15 p.

Research output: Contribution to journalReview article

Histones
Transcription Factors
Gene Regulatory Networks
Protein Subunits
Cell Lineage
27 Citations (Scopus)

N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells

Martínez-Cerdeño, V., Lemen, J. M., Chan, V., Wey, A., Lin, W., Dent, S. R. & Knoepfler, P. S., Jun 26 2012, In : PloS one. 7, 6, e39456.

Research output: Contribution to journalArticle

Neural Stem Cells
Stem cells
stem cells
Nestin
Gene expression
21 Citations (Scopus)

Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes

McCullough, S. D., Xu, X., Dent, S. Y. R., Bekiranov, S., Roeder, R. G. & Grant, P. A., Dec 26 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 52, p. 21319-21324 6 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Astrocytes
trichostatin A
Intranuclear Inclusion Bodies
Cerebellum
7 Citations (Scopus)

Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts

Polak, U., Hirsch, C., Ku, S., Gottesfeld, J., Dent, S. Y. R. & Napierala, M., Feb 20 2012, In : Journal of Visualized Experiments. 60, e3416.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Fibroblasts
Stem cells
Friedreich Ataxia
Cell Line

Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts.

Polak, U., Hirsch, C., Ku, S., Gottesfeld, J., Dent, S. Y. R. & Napierala, M., 2012, In : Journal of visualized experiments : JoVE. 60

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Fibroblasts
Stem cells
Friedreich Ataxia
Cell Line
2011
138 Citations (Scopus)

Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas

Xu, C. R., Cole, P. A., Meyers, D. J., Kormish, J., Dent, S. & Zaret, K. S., May 20 2011, In : Science. 332, 6032, p. 963-966 4 p.

Research output: Contribution to journalArticle

Histones
Chromatin
Pancreas
Histone Code
Liver
44 Citations (Scopus)

Chromatin signaling to kinetochores: Transregulation of Dam1 methylation by histone H2B ubiquitination

Latham, J. A., Chosed, R. J., Wang, S. & Dent, S. R., Sep 2 2011, In : Cell. 146, 5, p. 709-719 11 p.

Research output: Contribution to journalArticle

Kinetochores
Methylation
Ubiquitination
Histones
Chromatin
364 Citations (Scopus)

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

Jin, Q., Yu, L. R., Wang, L., Zhang, Z., Kasper, L. H., Lee, J. E., Wang, C., Brindle, P. K., Dent, S. R. & Ge, K., Jan 19 2011, In : EMBO Journal. 30, 2, p. 249-262 14 p.

Research output: Contribution to journalArticle

Cytoplasmic and Nuclear Receptors
Histone Acetyltransferases
Transcriptional Activation
Acetylation
Genes