Shilpa S. Dhar

Instructor

  • 740 Citations
  • 16 h-Index
20082019
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  • 18 Similar Profiles
Nuclear Respiratory Factor 1 Medicine & Life Sciences
Electron Transport Complex IV Medicine & Life Sciences
Neurons Medicine & Life Sciences
Genes Medicine & Life Sciences
Energy Metabolism Medicine & Life Sciences
Protein-Arginine N-Methyltransferases Medicine & Life Sciences
Histones Medicine & Life Sciences
Oxidoreductases Medicine & Life Sciences

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Research Output 2008 2019

  • 740 Citations
  • 16 h-Index
  • 22 Article
  • 1 Comment/debate
1 Citation (Scopus)

Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4

Liu, Y., Qin, S., Chen, T. Y., Lei, M., Dhar, S. S., Ho, J. C., Dong, A., Loppnau, P., Li, Y., Lee, M. G. & Min, J., Dec 1 2019, In : Nature communications. 10, 1, 36.

Research output: Contribution to journalArticle

methylation
Methylation
Histones
Methyltransferases
stem cells
7 Citations (Scopus)

HP1ɣ promotes lung adenocarcinoma by downregulating the transcription-repressive regulators NCOR2 and ZBTB7A

Alam, H., Li, N., Dhar, S. S., Wu, S. J., Lv, J., Chen, K., Flores, E. R., Baseler, L. & Lee, M. G., Jul 15 2018, In : Cancer research. 78, 14, p. 3834-3848 15 p.

Research output: Contribution to journalArticle

Down-Regulation
Histones
Methylation
Proteins
Messenger RNA
18 Citations (Scopus)

MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes

Dhar, S. S., Zhao, D., Lin, T., Gu, B., Pal, K., Wu, S. J., Alam, H., Lv, J., Yun, K., Gopalakrishnan, V., Flores, E. R., Northcott, P. A., Rajaram, V., Li, W., Shilatifard, A., Sillitoe, R. V., Chen, K. & Lee, M. G., Jun 7 2018, In : Molecular cell. 70, 5, p. 825-841.e6

Research output: Contribution to journalArticle

Tumor Suppressor Genes
Medulloblastoma
Epigenomics
Down-Regulation
Gene Expression
6 Citations (Scopus)
Protein-Arginine N-Methyltransferases
Stem cells
MicroRNAs
Clustered Regularly Interspaced Short Palindromic Repeats
Maintenance
23 Citations (Scopus)

A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

Lee, S. H., Chen, T. Y., Dhar, S. S., Gu, B., Chen, K., Kim, Y. Z., Li, W. & Lee, M. G., Dec 1 2016, In : Nucleic acids research. 44, 22, p. 10603-10618 16 p.

Research output: Contribution to journalArticle

Protein-Arginine N-Methyltransferases
Embryonic Stem Cells
MicroRNAs
Epigenomics
3' Untranslated Regions