Shuxing Zhang

Associate Professor

  • 3280 Citations
  • 31 h-Index
1993 …2019
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Research Output 1993 2019

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Review article
2017
26 Citations (Scopus)

Computational polypharmacology: a new paradigm for drug discovery

Chaudhari, R. R., Tan, Z., Huang, B. & Zhang, S., Mar 4 2017, In : Expert Opinion on Drug Discovery. 12, 3, p. 279-291 13 p.

Research output: Contribution to journalReview article

Polypharmacology
Drug Discovery
Drug Repositioning
Drug Costs
Drug Industry
2016
19 Citations (Scopus)

Polypharmacology in Drug Development: A Minireview of Current Technologies

Tan, Z., Chaudhai, R. & Zhang, S., Jan 1 2016, In : ChemMedChem. p. 1211-1218 8 p.

Research output: Contribution to journalReview article

Polypharmacology
Technology
Pharmaceutical Preparations
Drug Repositioning
Data Mining
2015
68 Citations (Scopus)

Small molecule compounds targeting miRNAs for cancer therapy

Monroig, P. D. C., Chen, L., Zhang, S. & Calin, G. A., Jan 1 2015, In : Advanced Drug Delivery Reviews. 81, p. 104-116 13 p.

Research output: Contribution to journalReview article

MicroRNAs
Neoplasms
Therapeutics
Untranslated RNA
Messenger RNA
23 Citations (Scopus)

Targeting ubiquitination for cancer therapies

Morrow, J. K., Lin, H. K., Sun, S. C. & Zhang, S., Nov 2015, In : Future Medicinal Chemistry. 7, 17, p. 2333-2350 18 p.

Research output: Contribution to journalReview article

Ubiquitination
Proteasome Endopeptidase Complex
Ubiquitin
Neoplasms
Ubiquitin-Protein Ligases
2013
183 Citations (Scopus)

Polypharmacology: Drug discovery for the future

Reddy, A. S. & Zhang, S., Jan 1 2013, In : Expert Review of Clinical Pharmacology. 6, 1, p. 41-47 7 p.

Research output: Contribution to journalReview article

Polypharmacology
Drug Discovery
Pharmaceutical Preparations
Poisons
Drug Interactions
2012
48 Citations (Scopus)

From laptop to benchtop to bedside:Structure-based drug design on protein targets

Chen, L., Morrow, J. K., Tran, H. T., Phatak, S. S., Du-Cuny, L. & Zhang, S., Mar 1 2012, In : Current pharmaceutical design. 18, 9, p. 1217-1239 23 p.

Research output: Contribution to journalReview article

Drug Design
Drug Discovery
Proteins
Polypharmacology
Drug Repositioning
2011
30 Citations (Scopus)

Computer-aided drug discovery and development.

Zhang, S., May 24 2011, In : Methods in molecular biology (Clifton, N.J.). 716, p. 23-38 16 p.

Research output: Contribution to journalReview article

Drug Discovery
Technology
Drug Design
Ligands
Therapeutics
163 Citations (Scopus)

First-pass metabolism via UDP-glucuronosyltransferase: A barrier to oral bioavailability of phenolics

Wu, B., Kulkarni, K., Basu, S., Zhang, S. & Hu, M., Sep 2011, In : Journal of Pharmaceutical Sciences. 100, 9, p. 3655-3681 27 p.

Research output: Contribution to journalReview article

Glucuronosyltransferase
Biological Availability
Polyphenols
Xenobiotics
Metabolic Networks and Pathways

Novel computational biology methods and their applications to drug discovery

Phatak, S. S., Tran, H. T. & Zhang, S., Aug 1 2011, In : Frontiers of Biology in China. 6, 4, p. 289-299 11 p.

Research output: Contribution to journalReview article

Drug Discovery
Computational Biology
bioinformatics
drug
drugs
2010
29 Citations (Scopus)

Molecular networks in drug discovery

Morrow, J. K., Tian, L. & Zhang, S., Jan 1 2010, In : Critical Reviews in Biomedical Engineering. 38, 2, p. 143-156 14 p.

Research output: Contribution to journalReview article

Toxicity
Bioinformatics
Electric network analysis
Ligands
Drug Discovery
89 Citations (Scopus)

Targeting MicroRNAs with small molecules: From dream to reality

Zhang, S., Chen, L., Jung, E. J. & Calin, G. A., Jun 1 2010, In : Clinical pharmacology and therapeutics. 87, 6, p. 754-758 5 p.

Research output: Contribution to journalReview article

MicroRNAs
Neoplasms
Untranslated RNA
Therapeutics
Proteins
2007
87 Citations (Scopus)

Serum response factor micromanaging cardiogenesis

Niu, Z., Li, A., Zhang, S. X. & Schwartz, R. J., Dec 1 2007, In : Current Opinion in Cell Biology. 19, 6, p. 618-627 10 p.

Research output: Contribution to journalReview article

Serum Response Factor
MicroRNAs
Contractile Proteins
Sarcomeres
Muscle Proteins