Swaminathan Padmanabhan Iyer

Professor

  • 3533 Citations
  • 29 h-Index
20032019
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Research Output 2003 2019

  • 3533 Citations
  • 29 h-Index
  • 64 Article
  • 11 Letter
  • 7 Review article
  • 2 Comment/debate
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Article
2019

Adoptive cell therapy for acute myeloid leukemia

Ma, H., Iyer, S. P., Parmar, S. & Gong, Y., Jun 1 2019, In : Leukemia & Lymphoma. 60, 6, p. 1370-1380 11 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Acute Myeloid Leukemia
Antigen Receptors
Natural Killer Cells
Immunotherapy

A pilot study to evaluate home-based screening for the common non-communicable diseases by a dedicated cadre of community health workers in a rural setting in India

Basu, P., Mahajan, M., Patira, N., Prasad, S., Mogri, S., Muwonge, R., Lucas, E., Sankaranarayanan, R., Iyer, S. P., Naik, N. & Jain, K., Jan 3 2019, In : BMC public health. 19, 1, 14.

Research output: Contribution to journalArticle

Open Access
India
Tobacco
Oral Diagnosis
Mouth Neoplasms
Blood Glucose
15 Citations (Scopus)

Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial

ECHELON-2 Study Group, Jan 19 2019, In : The Lancet. 393, 10168, p. 229-240 12 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Drug Therapy
Vincristine
Prednisone
Doxorubicin

Characteristics and Treatment of Advanced Breast Implant-Associated Anaplastic Large Cell Lymphoma

Collins, M. S., Miranda, R., Medeiros, L. J., Silva de Meneses, M. P., Iyer, S. P., Butler, C. E., Liu, J. & Clemens, M. W., Mar 1 2019, In : Plastic and reconstructive surgery. 143, 3 A Review of Breast ImplantAssociated Anaplastic Large Cell ..., p. 41S-50S

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Breast Implants
Therapeutics
Lymph Nodes
Radiation

Parsaclisib, a potent and highly selective PI3Kδ inhibitor, in patients with relapsed or refractory B-cell malignancies

Forero-Torres, A., Ramchandren, R., Yacoub, A., Wertheim, M. S., Edenfield, W. J., Caimi, P., Gutierrez, M., Akard, L., Escobar, C., Call, J., Persky, D., Iyer, S. P., DeMarini, D. J., Zhou, L., Chen, X., Dawkins, F. & Phillips, T. J., Apr 18 2019, In : Blood. 133, 16, p. 1742-1752 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Refractory materials
B-Lymphocytes
Cells
Non-Hodgkin's Lymphoma

Triple-hit lymphoma of the cavernous sinus

Tran, J., Vickers, A., Ponce, C. P., Iyer, S. P. & Lee, A. G., Apr 1 2019, In : Canadian Journal of Ophthalmology. 54, 2, p. e61-e66

Research output: Contribution to journalArticle

Cavernous Sinus
Lymphoma
2018
7 Citations (Scopus)

Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma

Qin, Q., Nan, X., Miller, T., Fisher, R., Teh, B., Pandita, S., Farach, A. M., Pingali, S. R., Pandita, R. K., Butler, E. B., Pandita, T. K. & Iyer, S. P., Sep 1 2018, In : Radiation research. 190, 3, p. 322-329 8 p.

Research output: Contribution to journalArticle

refractories
Hodgkin Disease
Radiation
inhibitors
radiation
2 Citations (Scopus)

Cryptococcal meningoencephalitis in patients with mantle cell lymphoma on ibrutinib

Sun, K., Kasparian, S., Iyer, S. P. & Pingali, S. R., May 17 2018, In : ecancermedicalscience. 12, 836.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Meningoencephalitis
B-Cell Chronic Lymphocytic Leukemia
Opportunistic Infections
Infection

Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma

Kelly, K. R., Friedberg, J. W., Park, S. I., McDonagh, K., Hayslip, J., Persky, D., Ruan, J., Puvvada, S., Rosen, P., Iyer, S. P., Stefanovic, A., Bernstein, S. H., Weitman, S., Karnad, A., Monohan, G., VanderWalde, A., Mena, R., Schmelz, M., Spier, C., Groshen, S. & 5 othersVenkatakrishnan, K., Zhou, X., Sheldon-Waniga, E., Jane Leonard, E. & Mahadevan, D., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6150-6159 10 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Vincristine
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Lymphoma, Large B-Cell, Diffuse
3 Citations (Scopus)

SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair

Chakraborty, S., Pandita, R. K., Hambarde, S., Mattoo, A. R., Charaka, V., Ahmed, K. M., Iyer, S. P., Hunt, C. R. & Pandita, T. K., Apr 27 2018, In : Food Science and Human Wellness. 2, p. 123-135 13 p.

Research output: Contribution to journalArticle

Open Access
Double-Stranded DNA Breaks
Ubiquitination
resection
DNA Damage
Recombinational DNA Repair

Use of PEG-asparaginase in a case of Hepatosplenic γδ T-cell lymphoma with long-term remission after stem cell transplantation

Sun, K., Sanchez, C. G., Pingali, S. R. & Iyer, S. P., Sep 20 2018, In : ecancermedicalscience. 12, 872.

Research output: Contribution to journalArticle

Asparaginase
T-Cell Lymphoma
Stem Cell Transplantation
Peripheral T-Cell Lymphoma
Peripheral Blood Stem Cell Transplantation
2017
1 Citation (Scopus)

Associations of ofatumumab exposure and treatment outcomes in patients with untreated CLL receiving chemoimmunotherapy

for the Hx-CD20-407 Study Investigators, Feb 1 2017, In : Leukemia and Lymphoma. 58, 2, p. 348-356 9 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Cyclophosphamide
Thymidine Kinase
B-Cell Chronic Lymphocytic Leukemia
Multivariate Analysis
1 Citation (Scopus)

Hematology oncology practice in the Asia-Pacific APHCON survey results from the 6th international hematologic malignancies conference: Bridging the gap 2015, Beijing, China

Huang, X. J., Liu, K., Ritchie, D., Andersson, B. S., Lu, J., Hou, J., Burguera, A. D. L. F., Wang, J. X., Yeoh, A., Yan, C., Zhou, D., Tan, D., Kim, D. W., Wu, D., Shpall, E., Kornblau, S. M., Neelapu, S. S., Hongeng, S., Li, J., Hu, J. & 22 othersZhang, L. S., Wang, L., Malhotra, P., Jiang, Q., Qin, Y., Wong, R., Champlin, R. E., Hagemeister, F. B., Westin, J. R., Iyer, S. P., Mathews, V., Wang, Y., Hu, Y., Xiao, Z., Shao, Z., Orlowski, R., Chim, C. S., Mulligan, S., Sanz, M., Ozawa, K., Parmar, S. & Issaragrisil, S., Jan 1 2017, In : Oncotarget. 8, 25, p. 41620-41630 11 p.

Research output: Contribution to journalArticle

Hematology
Hematologic Neoplasms
China
Practice Guidelines
Mobile Applications
3 Citations (Scopus)

Leukapheresis reduces 4-week mortality in acute myeloid leukemia patients with hyperleukocytosis–a retrospective study from a tertiary center

Nan, X., Qin, Q., Gentille, C., Ensor, J., Leveque, C., Pingali, S. R., Phan, A. T., Rice, L. & Iyer, S. P., Sep 2 2017, In : Leukemia and Lymphoma. 58, 9, p. 2110-2117 8 p.

Research output: Contribution to journalArticle

Leukapheresis
Acute Myeloid Leukemia
Retrospective Studies
Mortality
Leukostasis
2 Citations (Scopus)

Use of PEG-asparaginase in monomorphic epitheliotropic intestinal T-cell lymphoma, a disease with diagnostic and therapeutic challenges

Gentille, C., Qin, Q., Barbieri, A., Pingali, S. R. & Iyer, S. P., Sep 27 2017, In : ecancermedicalscience. 11, 771.

Research output: Contribution to journalArticle

T-Cell Lymphoma
Anthracyclines
Enteropathy-Associated T-Cell Lymphoma
Therapeutics
Investigational Therapies
2016
74 Citations (Scopus)

Results of the phase i trial of RG7112, a small-molecule MDM2 antagonist in leukemia

Andreeff, M., Kelly, K. R., Yee, K., Assouline, S., Strair, R., Popplewell, L., Bowen, D., Martinelli, G., Drummond, M. W., Vyas, P., Kirschbaum, M., Iyer, S. P., Ruvolo, V., Gonzalez, G. M. N., Huang, X., Chen, G., Graves, B., Blotner, S., Bridge, P., Jukofsky, L. & 6 othersMiddleton, S., Reckner, M., Rueger, R., Zhi, J., Nichols, G. & Kojima, K., Feb 15 2016, In : Clinical Cancer Research. 22, 4, p. 868-876 9 p.

Research output: Contribution to journalArticle

Leukemia
p53 Genes
Mutation
RG7112
Pharmacokinetics
2015
30 Citations (Scopus)

Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia

Zhao, N., Pei, S. N., Qi, J., Zeng, Z., Iyer, S. P., Lin, P., Tung, C. H. & Zu, Y., Oct 1 2015, In : Biomaterials. 67, p. 42-51 10 p.

Research output: Contribution to journalArticle

Oligonucleotides
Acute Myeloid Leukemia
Methotrexate
Cells
Biomarkers
16 Citations (Scopus)

Phase 1/1B trial of the heat shock protein 90 inhibitor NVP-AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma

Seggewiss-Bernhardt, R., Bargou, R. C., Goh, Y. T., Stewart, A. K., Spencer, A., Alegre, A., Bladé, J., Ottmann, O. G., Fernandez-Ibarra, C., Lu, H., Pain, S., Akimov, M. & Iyer, S. P., Jan 1 2015, In : Cancer. 121, 13, p. 2185-2192 8 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Multiple Myeloma
Maximum Tolerated Dose
5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide
Bortezomib
23 Citations (Scopus)

Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells

Fiskus, W. C., Sharma, S., Saha, S., Shah, B., Devaraj, S. G. T., Sun, B., Horrigan, S., Leveque, C., Zu, Y., Iyer, S. P. & Bhalla, K., Jun 9 2015, In : Leukemia. 29, 6, p. 1267-1278 12 p.

Research output: Contribution to journalArticle

Catenins
Histone Deacetylase Inhibitors
Myeloid Cells
Acute Myeloid Leukemia
Stem Cells
78 Citations (Scopus)

Randomized phase II trial comparing obinutuzumab (GA101) with rituximab in patients with relapsed CD20+ indolent B-Cell non-hodgkin lymphoma: Final analysis of the GAUSS study

Sehn, L. H., Goy, A., Offner, F. C., Martinelli, G., Caballero, M. D., Gadeberg, O., Baetz, T., Zelenetz, A. D., Gaidano, G., Fayad, L. E., Buckstein, R., Friedberg, J. W., Crump, M., Jaksic, B., Zinzani, P. L., Iyer, S. P., Sahin, D., Chai, A., Fingerle-Rowson, G. & Press, O. W., Oct 20 2015, In : Journal of Clinical Oncology. 33, 30, p. 3467-3474 8 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Lymphoma
Follicular Lymphoma
Safety
17 Citations (Scopus)

Romidepsin for the treatment of peripheral t-cell lymphoma

Iyer, S. P. & Foss, F. F., Jun 22 2015, In : Oncologist. 20, 9, p. 1084-1091 8 p.

Research output: Contribution to journalArticle

Lymphoma
Peripheral T-Cell Lymphoma
Therapeutics
romidepsin
Cutaneous T-Cell Lymphoma
7 Citations (Scopus)

Utility of 18fluoro-deoxyglucose positron emission tomography for prognosis and response assessments in a phase 2 study of romidepsin in patients with relapsed or refractory peripheral T-cell lymphoma

Horwitz, S., Coiffier, B., Foss, F., Prince, H. M., Sokol, L., Greenwood, M., Caballero, D., Morschhauser, F., Pinter-Brown, L., Iyer, S. P., Shustov, A., Nichols, J., Balser, J., Balser, B. & Pro, B., Jan 1 2015, In : Annals of Oncology. 26, 4, p. 774-779 6 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Deoxyglucose
Positron-Emission Tomography
Radiology
Education
2014
66 Citations (Scopus)

A Phase IB multicentre dose-determination study of BHQ880 in combination with anti-myeloma therapy and zoledronic acid in patients with relapsed or refractory multiple myeloma and prior skeletal-related events

Iyer, S. P., Beck, J. T., Stewart, A. K., Shah, J., Kelly, K. R., Isaacs, R., Bilic, S., Sen, S. & Munshi, N. C., Nov 1 2014, In : British Journal of Haematology. 167, 3, p. 366-375 10 p.

Research output: Contribution to journalArticle

zoledronic acid
Multiple Myeloma
Maximum Tolerated Dose
Bone Diseases
Bone Density
74 Citations (Scopus)

BET protein antagonist JQ1 is synergistically lethal with FLT3 Tyrosine Kinase Inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD

Fiskus, W. C., Sharma, S., Qi, J., Shah, B., Devaraj, S. G. T., Leveque, C., Portier, B. P., Iyer, S. P., Bradner, J. E. & Bhalla, K., Oct 1 2014, In : Molecular cancer therapeutics. 13, 10, p. 2315-2327 13 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Proteins
Apoptosis
Histone Deacetylase Inhibitors
94 Citations (Scopus)

Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells

Fiskus, W. C., Sharma, S., Qi, J., Valenta, J. A., Schaub, L. J., Shah, B., Peth, K., Portier, B. P., Rodriguez, M., Devaraj, S. G. T., Zhan, M., Sheng, J., Iyer, S. P., Bradner, J. E. & Bhalla, K., Jan 1 2014, In : Molecular Cancer Therapeutics. 13, 5, p. 1142-1154 13 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Acute Myeloid Leukemia
Histones
Inbred NOD Mouse
SCID Mice
123 Citations (Scopus)

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells

Fiskus, W. C., Sharma, S., Shah, B., Portier, B. P., Devaraj, S. G. T., Liu, K., Iyer, S. P., Bearss, D. & Bhalla, K., Nov 1 2014, In : Leukemia. 28, 11, p. 2155-2164 10 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Myeloid Cells
Acute Myeloid Leukemia
Histone Demethylases
CCAAT-Enhancer-Binding Proteins
51 Citations (Scopus)

Phase I study of MLN8237 - Investigational Aurora A kinase inhibitor - In relapsed/refractory multiple myeloma, non-Hodgkin lymphoma and chronic lymphocytic leukemia

Kelly, K. R., Shea, T. C., Goy, A., Berdeja, J. G., Reeder, C. B., McDonagh, K. T., Zhou, X., Danaee, H., Liu, H., Ecsedy, J. A., Niu, H., Benaim, E. & Iyer, S. P., Jan 1 2014, In : Investigational New Drugs. 32, 3, p. 489-499 11 p.

Research output: Contribution to journalArticle

Aurora Kinase A
B-Cell Chronic Lymphocytic Leukemia
Enteric-Coated Tablets
Multiple Myeloma
Non-Hodgkin's Lymphoma
97 Citations (Scopus)

Romidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: Pivotal study update demonstrates durable responses

Coiffier, B., Pro, B., Prince, H. M., Foss, F., Sokol, L., Greenwood, M., Caballero, D., Morschhauser, F., Wilhelm, M., Pinter-Brown, L., Iyer, S. P., Shustov, A., Nielsen, T., Nichols, J., Wolfson, J., Balser, B. & Horwitz, S., Jan 23 2014, In : Journal of Hematology and Oncology. 7, 1, 11.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Therapeutics
romidepsin
Cutaneous T-Cell Lymphoma
Histone Deacetylase Inhibitors
2013
31 Citations (Scopus)

A multicentre, phase II trial of ofatumumab monotherapy in relapsed/progressive diffuse large B-cell lymphoma

Coiffier, B., Radford, J., Bosly, A., Martinelli, G., Barca, G., Davies, A., Decaudin, D., Gallop-Evans, E., Iyer, S. P., Van Eygen, K., Wu, K. L., Gupta, I. V., Lin, T. S., Goldstein, N., Jewell, R. C., Winter, P. & Lisby, S., Nov 1 2013, In : British Journal of Haematology. 163, 3, p. 334-342 9 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Transplantation
Lymphopenia
Leukopenia
Stem Cell Transplantation
27 Citations (Scopus)

Clinical and laboratory studies of the novel cyclin-dependent kinase inhibitor dinaciclib (SCH 727965) in acute leukemias

Gojo, I., Sadowska, M., Walker, A., Feldman, E. J., Iyer, S. P., Baer, M. R., Sausville, E. A., Lapidus, R. G., Zhang, D., Zhu, Y., Jou, Y. M., Poon, J., Small, K. & Bannerji, R., Oct 1 2013, In : Cancer chemotherapy and pharmacology. 72, 4, p. 897-908 12 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Leukemia
Pharmacodynamics
Pharmacokinetics
alvocidib
25 Citations (Scopus)

Pharmacokinetic study of omacetaxine mepesuccinate administered subcutaneously to patients with advanced solid and hematologic tumors

Nemunaitis, J., Mita, A., Stephenson, J., Mita, M. M., Sarantopoulos, J., Iyer, S. P., Nanda, N., Gleich, L., Benichou, A. C. & Craig, A., Jan 1 2013, In : Cancer Chemotherapy and Pharmacology. 71, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Tumors
Plasmas
Metabolites
Neoplasms
2012
130 Citations (Scopus)

Aphase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma

Benson, D. M., Hofmeister, C. C., Iyer, S. P., Suvannasankha, A., Jagannath, S., Abonour, R., Bakan, C., Andre, P., Efebera, Y., Tiollier, J., Caligiuri, M. A. & Farag, S. S., Nov 22 2012, In : Blood. 120, 22, p. 4324-4333 10 p.

Research output: Contribution to journalArticle

KIR Receptors
Multiple Myeloma
Refractory materials
Pharmacodynamics
Pharmacokinetics

Bridging the gap in hematological malignancies

Parmar, S. & Iyer, S. P., Jun 1 2012, In : Expert Review of Hematology. 5, 3, p. 257-259 3 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Physicians
Medical Faculties
Singapore
Hong Kong
25 Citations (Scopus)

Phase I/II multicenter study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD4877 in patients with refractory acute myeloid leukemia

Kantarjian, H. M., Iyer, S. P., Stock, W., Tallman, M. S., Curt, G. A., Li, J., Osmukhina, A., Wu, K., Huszar, D., Borthukar, G., Faderl, S., Garcia-Manero, G., Kadia, T. M., Sankhala, K., Odenike, O., Altman, J. K. & Minden, M., Jun 1 2012, In : Investigational New Drugs. 30, 3, p. 1107-1115 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Multicenter Studies
Pharmacokinetics
Safety
Maximum Tolerated Dose
331 Citations (Scopus)

Results from a pivotal, open-label, phase II study of romidepsin in relapsed or refractory peripheral T-cell lymphoma after prior systemic therapy

Coiffier, B., Pro, B., Prince, H. M., Foss, F., Sokol, L., Greenwood, M., Caballero, D., Borchmann, P., Morschhauser, F., Wilhelm, M., Pinter-Brown, L., Iyer, S. P., Shustov, A., Nichols, J., Carroll, S., Balser, J., Balser, B. & Horwitz, S., Feb 20 2012, In : Journal of Clinical Oncology. 30, 6, p. 631-636 6 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Therapeutics
Drug Approval
Histone Deacetylase Inhibitors
Stem Cell Transplantation
33 Citations (Scopus)

Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO-dependent mechanism

Kelly, K. R., Nawrocki, S. T., Espitia, C. M., Zhang, M., Yang, J. J., Iyer, S. P., Ecsedy, J., Giles, F. J. & Carew, J. S., Dec 1 2012, In : International Journal of Cancer. 131, 11, p. 2693-2703 11 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Cytarabine
Acute Myeloid Leukemia
Myeloid Cells
Investigational Drugs
14 Citations (Scopus)
Myeloid Leukemia
Wilms Tumor
Myeloid Cells
Tumors
Transcription Factors
2011
3 Citations (Scopus)

A comparison of races and leukemia subtypes among patients in different cancer survivorship phases

Pandya, D. M., Patel, S., Ketchum, N. S., Pollock, B. H. & Iyer, S. P., Jun 1 2011, In : Clinical Lymphoma, Myeloma and Leukemia. 11, SUPPL.1

Research output: Contribution to journalArticle

Leukemia
Survival Rate
Survival
Neoplasms
Hispanic Americans
27 Citations (Scopus)

A prospective rAnDomised study of a rotary powered device (OnControl) for Bone marrow aspiration and biopsy

Swords, R. T., Anguita, J., Higgins, R. A., Yunes, A. C., Naski, M., Iyer, S. P., Kelly, K. R., Mahalingam, D., Philbeck, T., Miller, L., Puga, T. A., Giles, F. J., Kinney, M. C. & Brenner, A. J., Sep 1 2011, In : Journal of Clinical Pathology. 64, 9, p. 809-813 5 p.

Research output: Contribution to journalArticle

Needle Biopsy
Bone Marrow
Prospective Studies
Equipment and Supplies
Pain
99 Citations (Scopus)

Chemoimmunotherapy with O-FC in previously untreated patients with chronic lymphocytic leukemia

Wierda, W. G., Kipps, T. J., Dürig, J., Griskevicius, L., Stilgenbauer, S., Mayer, J., Smolej, L., Hess, G., Griniute, R., Hernandez-Ilizaliturri, F. J., Iyer, S. P., Gorczyca, M., Chang, C. N., Chan, G., Gupta, I., Nielsen, T. G. & Russell, C. A., Jun 16 2011, In : Blood. 117, 24, p. 6450-6458 9 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Cyclophosphamide
Patient treatment
Terminology
National Cancer Institute (U.S.)
135 Citations (Scopus)

Ofatumumab is active in patients with fludarabine-refractory CLL irrespective of prior rituximab: Results from the phase 2 international study

Wierda, W. G., Iyer, S. P., Chan, G. W., Gupta, I. V., Lisby, S. & Österborg, A., Nov 10 2011, In : Blood. 118, 19, p. 5126-5129 4 p.

Research output: Contribution to journalArticle

Refractory materials
B-Cell Chronic Lymphocytic Leukemia
fludarabine
ofatumumab
Rituximab
65 Citations (Scopus)

The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib

Kelly, K. R., Ecsedy, J., Medina, E., Mahalingam, D., Iyer, S. P., Nawrocki, S. T., Giles, F. J. & Carew, J. S., Oct 1 2011, In : Journal of Cellular and Molecular Medicine. 15, 10, p. 2057-2070 14 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Phosphotransferases
Myeloid Cells
Aurora Kinases
62 Citations (Scopus)

Tumor flare reaction associated with lenalidomide treatment in patients with chronic lymphocytic leukemia predicts clinical response

Chanan-Khan, A., Miller, K. C., Lawrence, D., Iyer, S. P., Miller, A., Hernandez-Illatazurri, F., Czuczman, M. S., Wallace, P. K., Zeldis, J. B. & Lee, K., May 15 2011, In : Cancer. 117, 10, p. 2127-2135 9 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Neoplasms
Therapeutics
lenalidomide
Cellular Microenvironment
2010
27 Citations (Scopus)

Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias

Bansal, H., Bansal, S., Rao, M., Foley, K. P., Sang, J., Proia, D. A., Blackman, R. K., Ying, W., Barsoum, J., Baer, M. R., Kelly, K., Swords, R., Tomlinson, G. E., Battiwalla, M., Giles, F. J., Lee, K. P. & Iyer, S. P., Nov 25 2010, In : Blood. 116, 22, p. 4591-4599 9 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Myeloid Leukemia
Wilms Tumor
Tumors
Proteins
144 Citations (Scopus)

Inhibition of NEDD8-activating enzyme: A novel approach for the treatment of acute myeloid leukemia

Swords, R. T., Kelly, K. R., Smith, P. G., Garnsey, J. J., Mahalingam, D., Medina, E., Oberheu, K., Iyer, S. P., O'Dwyer, M., Nawrocki, S. T., Giles, F. J. & Carew, J. S., May 6 2010, In : Blood. 115, 18, p. 3796-3800 5 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Enzymes
fms-Like Tyrosine Kinase 3
Bearings (structural)
Cullin Proteins
452 Citations (Scopus)

Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia

Wierda, W. G., Kipps, T. J., Mayer, J., Stilgenbauer, S., Williams, C. D., Hellmann, A., Robak, T., Furman, R. R., Hillmen, P., Trneny, M., Dyer, M. J. S., Iyer, S. P., Piotrowska, M., Kozak, T., Chan, G., Davis, R., Losic, N., Wilms, J., Russell, C. A. & Österborg, A., Apr 1 2010, In : Journal of Clinical Oncology. 28, 10, p. 1749-1755 7 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Immunotherapy
Therapeutics
National Cancer Institute (U.S.)
ofatumumab
93 Citations (Scopus)

Phase II trial of weekly bortezomib in combination with rituximab in relapsed or relapsed and refractory Waldenström macroglobulinemia

Ghobrial, I. M., Hong, F., Iyer, S. P., Badros, A., Rourke, M., Leduc, R., Chuma, S., Kunsman, J., Warren, D., Harris, B., Sam, A., Anderson, K. C., Richardson, P. G., Treon, S. P., Weller, E. & Matous, J., Mar 10 2010, In : Journal of Clinical Oncology. 28, 8, p. 1422-1428 7 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Bortezomib
Rituximab
Viral Pneumonia
Peripheral Nervous System Diseases
86 Citations (Scopus)

Phase II trial of weekly bortezomib in combination with rituximab in untreated patients with Waldenström Macroglobulinemia

Ghobrial, I. M., Xie, W., Iyer, S. P., Badros, A., Rourke, M., Leduc, R., Chuma, S., Kunsman, J., Warren, D., Poon, T., Harris, B., Sam, A., Anderson, K. C., Richardson, P. G., Treon, S. P., Weller, E. & Matous, J., Jan 1 2010, In : American Journal of Hematology. 85, 9, p. 670-674 5 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Bortezomib
Rituximab
Neutropenia
Thrombocytopenia
2009

Acute lymphoblastic leukemia presenting with avascular necrosis of the elbow

Kelly, K., Swords, R., Kilcoyne, A., Sankhala, K., Mahalingam, D., Iyer, S. P. & Giles, F., Mar 6 2009, In : Leukemia and Lymphoma. 50, 2, p. 297-299 3 p.

Research output: Contribution to journalArticle

Elbow
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Young Adult
Necrosis
Magnetic Resonance Imaging