• 5985 Citations
  • 39 h-Index
19932018
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Fingerprint Dive into the research topics where Ursula Klingmüller is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Erythropoietin Receptors Medicine & Life Sciences
Systems Biology Medicine & Life Sciences
Signal transduction Chemical Compounds
Erythropoietin Medicine & Life Sciences
Signal Transduction Medicine & Life Sciences
Phosphorylation Chemical Compounds
Chemical activation Chemical Compounds
Cells Chemical Compounds

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Research Output 1993 2018

3 Citations (Scopus)

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification

Melnik, S., Dvornikov, D., Müller-Decker, K., Depner, S., Stannek, P., Meister, M., Warth, A., Thomas, M., Muley, T., Risch, A., Plass, C., Klingmüller, U., Niehrs, C. & Glinka, A., Dec 1 2018, In : Cell Discovery. 4, 1, 37.

Research output: Contribution to journalArticle

Catenins
Acidification
Metformin
Cells
Tumors
3 Citations (Scopus)

Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response

Dvornikov, D., Schneider, M. A., Ohse, S., Szczygieł, M., Titkova, I., Rosenblatt, M., Muley, T., Warth, A., Herth, F. J., Dienemann, H., Thomas, M., Timmer, J., Schilling, M., Busch, H., Boerries, M., Meister, M. & Klingmüller, U., Dec 1 2018, In : Scientific reports. 8, 1, 9517.

Research output: Contribution to journalArticle

Squamous Cell Neoplasms
Transforming Growth Factors
Myosins
Lung Neoplasms
Drug Therapy
3 Citations (Scopus)

Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds

Oppelt, A., Kaschek, D., Huppelschoten, S., Sison-Young, R., Zhang, F., Buck-Wiese, M., Herrmann, F., Malkusch, S., Krüger, C. L., Meub, M., Merkt, B., Zimmermann, L., Schofield, A., Jones, R. P., Malik, H., Schilling, M., Heilemann, M., van de Water, B., Goldring, C. E., Park, B. K. & 2 others, Timmer, J. & Klingmüller, U., Dec 1 2018, In : npj Systems Biology and Applications. 4, 1, 23.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Tumor Necrosis Factor
Signal transduction
Signal Transduction
Diclofenac
10 Citations (Scopus)

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression

Lucarelli, P., Schilling, M., Kreutz, C., Vlasov, A., Boehm, M. E., Iwamoto, N., Steiert, B., Lattermann, S., Wäsch, M., Stepath, M., Matter, M. S., Heikenwälder, M., Hoffmann, K., Deharde, D., Damm, G., Seehofer, D., Muciek, M., Gretz, N., Lehmann, W. D., Timmer, J. & 1 others, Klingmüller, U., Jan 24 2018, In : Cell Systems. 6, 1, p. 75-89.e11

Research output: Contribution to journalArticle

Smad Proteins
Hepatocellular Carcinoma
Gene Expression
Phosphorylation
Transforming Growth Factors
9 Citations (Scopus)

Whither systems medicine?

Apweiler, R., Beissbarth, T., Berthold, M. R., Blüthgen, N., Burmeister, Y., Dammann, O., Deutsch, A., Feuerhake, F., Franke, A., Hasenauer, J., Hoffmann, S., Höfer, T., Jansen, P. L. M., Kaderali, L., Klingmüller, U., Koch, I., Kohlbacher, O., Kuepfer, L., Lammert, F., Maier, DI. & 12 others, Pfeifer, N., Radde, N., Rehm, M., Roeder, I., Saez-Rodriguez, J., Sax, U., Schmeck, B., Schuppert, A., Seilheimer, B., Theis, F. J., Vera, J. & Wolkenhauer, O., Mar 2 2018, In : Experimental and Molecular Medicine. 50, 3, e453.

Research output: Contribution to journalReview article

Systems Analysis
Medicine
Biostatistics
Informatics
Translational Medical Research