• 4298 Citations
  • 34 h-Index
19972019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1997 2019

Filter
Article
2019

GnRH-R-Targeted lytic peptide sensitizes BRCA wild-type ovarian cancer to PARP inhibition

Ma, S., Pradeep, S., Villar-Prados, A., Wen, Y., Bayraktar, E., Mangala, L. S., Kim, M. S., Wu, S., Hu, W., Rodriguez-Aguayo, C., Leuschner, C., Liang, X., Ram, P., Schlacher, K., Coleman, R. & Sood, A. K., Jan 1 2019, In : Molecular cancer therapeutics. 18, 5, p. 969-979 11 p.

Research output: Contribution to journalArticle

Gonadotropin-Releasing Hormone
Ovarian Neoplasms
Peptides
Protein Array Analysis
Comet Assay
3 Citations (Scopus)

PRKRA/PACT expression promotes chemoresistance of mucinous ovarian cancer

Hisamatsu, T., McGuire, M., Wu, S., Rupaimoole, R., Pradeep, S., Bayraktar, E., Noh, K., Hu, W., Hansen, J. M., Lyons, Y. A., Gharpure, K. M., Nagaraja, A. S., Mangala, L. S., Mitamura, T., Rodriguez-Aguayo, C., Eun, Y. G., Rose, J., Bartholomeusz, G., Ivan, C., Lee, J-S. & 5 others, Matsuo, K., Frumovitz, M., Wong, K. K., Lopez, G. & Sood, A. K., Jan 1 2019, In : Molecular cancer therapeutics. 18, 1, p. 162-172 11 p.

Research output: Contribution to journalArticle

oxaliplatin
Ovarian Neoplasms
Small Interfering RNA
Platinum
Phosphotransferases

Prospective pilot trial with combination of propranolol with chemotherapy in patients with epithelial ovarian cancer and evaluation on circulating immune cell gene expression

Ramondetta, L. M., Hu, W., Thaker, P. H., Urbauer, D. L., Chisholm, G. B., Westin, S. N., Sun, Y., Ramirez, P. T., Fleming, N., Sahai, S. K., Nick, A. M., Arevalo, J. M. G., Dizon, T., Coleman, R., Cole, S. W. & Sood, A. K., Sep 1 2019, In : Gynecologic oncology. 154, 3, p. 524-530 7 p.

Research output: Contribution to journalArticle

Interleukin-8
Propranolol
Interleukin-10
Ovarian Neoplasms
Interleukin-6
2018
2 Citations (Scopus)

ADH1B promotes mesothelial clearance and ovarian cancer infiltration

Gharpure, K. M., Lara, O. D., Wen, Y., Pradeep, S., LaFargue, C., Ivan, C., Rupaimoole, R., Hu, W., Mangala, L. S., Wu, S., Nagaraja, A. S., Baggerly, K. A. & Sood, A. K., May 18 2018, In : Oncotarget. 9, 38, p. 25115-25126 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Adjuvant Chemotherapy
Cell Adhesion
Extracellular Matrix
9 Citations (Scopus)

FABP4 as a key determinant of metastatic potential of ovarian cancer

Gharpure, K. M., Pradeep, S., Sans, M., Rupaimoole, R., Ivan, C., Wu, S., Bayraktar, E., Nagaraja, A. S., Mangala, L. S., Zhang, X., Haemmerle, M., Hu, W., Rodriguez-Aguayo, C., McGuire, M., Mak, S. L. CELIA., Chen, X., Tran, M. A., Villar-Prados, A., Pena, G. A., Kondetimmanahalli, R. & 8 others, Nini, R., Koppula, P., Ram, P., Liu, J., Lopez, G., Baggerly, K. A., S. Eberlin, L. & Sood, A. K., Dec 1 2018, In : Nature communications. 9, 1, 2923.

Research output: Contribution to journalArticle

determinants
Ovarian Neoplasms
cancer
Cells
Surgery
3 Citations (Scopus)

Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma

Matsuo, K., Wong, K. K., Fotopoulou, C., Blake, E. A., Robertson, S. E., Pejovic, T., Frimer, M., Pardeshi, V., Hu, W., Choi, J. S., Sun, C. C., Richmond, A. M., Marcus, J. Z., Hilliard, M. A. M., Mostofizadeh, S., Mhawech-Fauceglia, P., Abdulfatah, E., Post, M. D., Saglam, O., Shahzad, M. M. K. & 6 others, Karabakhtsian, R. G., Ali-Fehmi, R., Gabra, H., Roman, L. D., Sood, A. K. & Gershenson, D. M., Feb 1 2018, In : Journal of Surgical Oncology. 117, 2, p. 236-244 9 p.

Research output: Contribution to journalArticle

Blood Vessels
Carcinoma
Survival
Neoplasms
Odds Ratio

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

Mangala, L. S., Wang, H., Jiang, D., Wu, S., Somasunderam, A., Volk, D. E., Lokesh, G. L. R., Li, X., Pradeep, S., Yang, X., Haemmerle, M., Rodriguez-Aguayo, C., Nagaraja, A. S., Rupaimoole, R., Bayraktar, E., Bayraktar, R., Li, L., Tanaka, T., Hu, W., Ivan, C. & 13 others, Gharpure, K. M., McGuire, M. H., Thiviyanathan, V., Zhang, X., Maiti, S. N., Bulayeva, N., Choi, H. J., Dorniak, P. L., Cooper, L. J., Rosenblatt, K. P., Lopez, G., Gorenstein, D. G. & Sood, A. K., Jun 7 2018, In : JCI insight. 3, 11

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP)

Mitamura, T., Pradeep, S., McGuire, M., Wu, S., Ma, S., Hatakeyama, H., Lyons, Y. A., Hisamatsu, T., Noh, K., Villar-Prados, A., Chen, X., Ivan, C., Rodriguez-Aguayo, C., Hu, W., Lopez, G., Coleman, R. & Sood, A. K., Feb 8 2018, In : Oncogene. 37, 6, p. 722-731 10 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Neoplasms
Therapeutics
R Factors
Acetylation

Inhibiting nuclear phospho-progesterone receptor enhances antitumor activity of onapristone in uterine cancer

Huang, Y., Hu, W., Huang, J., Shen, F., Sun, Y., Ivan, C., Pradeep, S., Dood, R., Haemmerle, M., Jiang, D., Mangala, L. S., Noh, K., Hansen, J. M., Dalton, H. J., Previs, R. A., Nagaraja, A. S., McGuire, M., Jennings, N. B., Broaddus, R., Coleman, R. & 1 others, Sood, A. K., Feb 1 2018, In : Molecular cancer therapeutics. 17, 2, p. 464-473 10 p.

Research output: Contribution to journalArticle

Uterine Neoplasms
Progesterone Receptors
Epidermal Growth Factor
Ligands
onapristone
7 Citations (Scopus)

Paclitaxel with and without pazopanib for persistent or recurrent ovarian cancer: A randomized clinical trial

Richardson, D. L., Sill, M. W., Coleman, R., Sood, A. K., Pearl, M. L., Kehoe, S. M., Carney, M. E., Hanjani, P., Van Le, L., Zhou, X. C., Secord, A. A., Gray, H. J., Landrum, L. M., Lankes, H. A., Hu, W. & Aghajanian, C., Feb 1 2018, In : JAMA Oncology. 4, 2, p. 196-202 7 p.

Research output: Contribution to journalArticle

Paclitaxel
Ovarian Neoplasms
Randomized Controlled Trials
Disease-Free Survival
Hypoxia-Inducible Factor 1
8 Citations (Scopus)

Sustained adrenergic signaling promotes intratumoral innervation through BDNF induction

Allen, J. K., Armaiz-Pena, G. N., Nagaraja, A. S., Sadaoui, N. C., Ortiz, T., Dood, R., Ozcan, M., Herder, D. M., Haemmerle, M., Gharpure, K. M., Rupaimoole, R., Previs, R. A., Wu, S., Pradeep, S., Xu, X., Han, H. D., Zand, B., Dalton, H. J., Taylor, M., Hu, W. & 15 others, Bottsford-Miller, J., Moreno-Smith, M., Kang, Y., Mangala, L. S., Rodriguez-Aguayo, C., Sehgal, V., Spaeth, E. L., Ram, P., Wong, S. T. C., Marini, F. C., Lopez, G., Cole, S. W., Lutgendorf, S. K., De Biasi, M. & Sood, A. K., Jun 15 2018, In : Cancer Research. 78, 12, p. 3233-3242 10 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Adrenergic Agents
Tumor Microenvironment
Neoplasms
TYK2 Kinase
2017
4 Citations (Scopus)

Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis

Noh, K., Mangala, L. S., Han, H. D., Zhang, N., Pradeep, S., Wu, S., Ma, S., Mora, E., Rupaimoole, R., Jiang, D., Wen, Y., Shahzad, M. M. K., Lyons, Y. A., Cho, M. S., Hu, W., Nagaraja, A. S., Haemmerle, M., Mak, S. L. CELIA., Chen, X., Gharpure, K. M. & 11 others, Deng, H., Xiong, W., Kingsley, C. V., Liu, J., Jennings, N., Birrer, M. J., Bouchard, R. R., Lopez, G., Coleman, R., An, Z. & Sood, A. K., Dec 5 2017, In : Cell Reports. 21, 10, p. 2785-2795 11 p.

Research output: Contribution to journalArticle

Tumors
Wounds and Injuries
Neoplasms
Wound Healing
Endothelial cells
12 Citations (Scopus)

Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy

Lyons, Y. A., Pradeep, S., Wu, S., Haemmerle, M., Hansen, J. M., Wagner, M. J., Villar-Prados, A., Nagaraja, A. S., Dood, R. L., Previs, R. A., Hu, W., Zhao, Y., Mak, D. H., Xiao, Z., Melendez, B. D., Lizee, G. A., Mercado-Uribe, I., Baggerly, K. A., Hwu, P., Liu, J. & 3 others, Overwijk, W., Coleman, R. & Sood, A. K., Jan 1 2017, In : Oncotarget. 8, 57, p. 96496-96505 10 p.

Research output: Contribution to journalArticle

Colony-Stimulating Factor Receptors
Macrophage Colony-Stimulating Factor
Vascular Endothelial Growth Factor A
Macrophages
Anti-Idiotypic Antibodies
16 Citations (Scopus)

Macrophages facilitate resistance to anti-VEGF therapy by altered VEGFR expression

Dalton, H. J., Pradeep, S., McGuire, M., Hailemichael, Y., Ma, S., Lyons, Y. A., Armaiz-Pena, G. N., Previs, R. A., Hansen, J. M., Rupaimoole, R., Gonzalez-Villasana, V., Cho, M. S., Wu, S., Mangala, L. S., Jennings, N. B., Hu, W., Langley, R., Mu, H., Andreeff, M., Bar Eli, M. & 5 others, Overwijk, W., Ram, P., Lopez, G., Coleman, R. & Sood, A. K., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 7034-7046 13 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Macrophages
Anti-Idiotypic Antibodies
Therapeutics
Neoplasms
2 Citations (Scopus)

Phase II trial of bevacizumab with dose-dense paclitaxel as first-line treatment in patients with advanced ovarian cancer

Fleming, N., Coleman, R., Tung, C., Westin, S. N., Hu, W., Sun, Y., Bhosale, P. R., Munsell, M. F. & Sood, A. K., Oct 1 2017, In : Gynecologic Oncology. 147, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

Paclitaxel
Ovarian Neoplasms
Therapeutics
Carboplatin
Disease-Free Survival
38 Citations (Scopus)

Platelets reduce anoikis and promote metastasis by activating YAP1 signaling

Haemmerle, M., Taylor, M. L., Gutschner, T., Pradeep, S., Cho, M. S., Sheng, J., Lyons, Y. A., Nagaraja, A. S., Dood, R. L., Wen, Y., Mangala, L. S., Hansen, J. M., Rupaimoole, R., Gharpure, K. M., Rodriguez-Aguayo, C., Yim, S. Y., Lee, J-S., Ivan, C., Hu, W., Lopez, G. & 6 others, Wong, S. T., Karlan, B. Y., Levine, D. A., Liu, J., Afshar-Kharghan, V. & Sood, A. K., Dec 1 2017, In : Nature Communications. 8, 1, 310.

Research output: Contribution to journalArticle

Anoikis
metastasis
Platelets
platelets
Blood Platelets
2016
18 Citations (Scopus)

Adrenergic stimulation of DUSP1 impairs chemotherapy response in ovarian cancer

Kang, Y., Nagaraja, A. S., Armaiz-Pena, G. N., Dorniak, P. L., Hu, W., Rupaimoole, R., Liu, T., Gharpure, K. M., Previs, R. A., Hansen, J. M., Rodriguez-Aguayo, C., Ivan, C., Ram, P., Sehgal, V., Lopez, G., Lutgendorf, S. K., Cole, S. W. & Sood, A. K., Apr 1 2016, In : Clinical Cancer Research. 22, 7, p. 1713-1724 12 p.

Research output: Contribution to journalArticle

Adrenergic Agents
Ovarian Neoplasms
Apoptosis
Drug Therapy
Gene Silencing
16 Citations (Scopus)

Antitumor and antiangiogenic effects of aspirin-PC in ovarian cancer

Huang, Y., Lichtenberger, L. M., Taylor, M., Bottsford-Miller, J. N., Haemmerle, M., Wagner, M. J., Lyons, Y. A., Pradeep, S., Hu, W., Previs, R. A., Hansen, J. M., Fang, D., Dorniak, P. L., Filant, J., Dial, E. J., Shen, F., Hatakeyama, H. & Sood, A. K., Dec 1 2016, In : Molecular cancer therapeutics. 15, 12, p. 2894-2904 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Aspirin
Growth
Vascular Endothelial Growth Factor A
Pharmaceutical Preparations
12 Citations (Scopus)

Dll4 Inhibition plus Aflibercept markedly reduces ovarian tumor growth

Huang, J., Hu, W., Hu, L., Previs, R. A., Dalton, H. J., Yang, X. Y., Sun, Y., McGuire, M., Rupaimoole, R., Nagaraja, A. S., Kang, Y., Liu, T., Nick, A. M., Jennings, N. B., Coleman, R., Jaffe, R. B. & Sood, A. K., Jun 1 2016, In : Molecular cancer therapeutics. 15, 6, p. 1344-1352 9 p.

Research output: Contribution to journalArticle

Growth
Neoplasms
Vascular Endothelial Growth Factor A
docetaxel
Ovarian Neoplasms
16 Citations (Scopus)

Role of Increased n-acetylaspartate Levels in Cancer

Zand, B., Previs, R. A., Millward, N. M. Z., Rupaimoole, R., Mitamura, T., Nagaraja, A. S., Guindani, M., Dalton, H. J., Yang, L., Baddour, J., Achreja, A., Hu, W., Pecot, C. V., Ivan, C., Wu, S., McCullough, C. R., Gharpure, K. M., Shoshan, E., Pradeep, S., Mangala, L. S. & 13 others, Rodriguez-Aguayo, C., Wang, Y., Nick, A. M., Davies, M. A., Armaiz-Pena, G., Liu, J., Lutgendorf, S. K., Baggerly, K. A., Bar Eli, M., Lopez, G., Nagrath, D., Bhattacharya, P. K. & Sood, A. K., Jun 1 2016, In : Journal of the National Cancer Institute. 108, 6, djv426.

Research output: Contribution to journalArticle

Small Interfering RNA
Neoplasms
aspartate N-acetyltransferase
Ovarian Neoplasms
Survival
2015
40 Citations (Scopus)

Differential platelet levels affect response to taxane-based therapy in ovarian cancer

Bottsford-Miller, J., Choi, H. J., Dalton, H. J., Stone, R. L., Cho, M. S., Haemmerle, M., Nick, A. M., Pradeep, S., Zand, B., Previs, R. A., Pecot, C. V., Crane, E. K., Hu, W., Lutgendorf, S. K., Afshar-Kharghan, V. & Sood, A. K., Feb 1 2015, In : Clinical Cancer Research. 21, 3, p. 602-610 9 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Blood Platelets
docetaxel
Tumor Burden
Therapeutics
22 Citations (Scopus)

Erythropoietin Stimulates Tumor Growth via EphB4

Pradeep, S., Huang, J., Mora, E. M., Nick, A. M., Cho, M. S., Wu, S., Noh, K., Pecot, C. V., Rupaimoole, R., Stein, M. A., Brock, S., Wen, Y., Xiong, C., Gharpure, K., Hansen, J. M., Nagaraja, A. S., Previs, R. A., Vivas-Mejia, P., Han, H. D., Hu, W. & 26 others, Mangala, L. S., Zand, B., Stagg, L. J., Ladbury, J. E., Ozpolat, B., Alpay, S. N., Nishimura, M., Stone, R. L., Matsuo, K., Armaiz-Peña, G. N., Dalton, H. J., Danes, C., Goodman, B., Rodriguez-Aguayo, C., Kruger, C., Schneider, A., Haghpeykar, S., Jaladurgam, P., Hung, M-C., Coleman, R., Liu, J., Li, C., Urbauer, D., Lopez, G., Jackson, D. B. & Sood, A. K., Nov 9 2015, In : Cancer Cell. 28, 5, p. 610-622 13 p.

Research output: Contribution to journalArticle

Erythropoietin
Growth
Neoplasms
Survival
Ovarian Neoplasms
31 Citations (Scopus)

Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer

Wen, Y., Graybill, W. S., Previs, R. A., Hu, W., Ivan, C., Mangala, L. S., Zand, B., Nick, A. M., Jennings, N. B., Dalton, H. J., Sehgal, V., Ram, P., Lee, J-S., Vivas-Mejia, P. E., Coleman, R. & Sood, A. K., Jan 15 2015, In : Clinical Cancer Research. 21, 2, p. 448-459 12 p.

Research output: Contribution to journalArticle

Folate Receptor 1
Autophagy
Folic Acid
Ovarian Neoplasms
Immunotherapy
6 Citations (Scopus)

PTEN expression as a predictor of response to focal adhesion kinase inhibition in uterine cancer

Thanapprapasr, D., Previs, R. A., Hu, W., Ivan, C., Armaiz-Pena, G. N., Dorniak, P. L., Hansen, J. M., Rupaimoole, R., Huang, J., Dalton, H. J., Ali-Fehmi, R., Coleman, R. & Sood, A. K., Jun 1 2015, In : Molecular cancer therapeutics. 14, 6, p. 1466-1475 10 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Uterine Neoplasms
Therapeutics
Topotecan
In Situ Nick-End Labeling
8 Citations (Scopus)

XPO1/CRM1 inhibition causes antitumor effects by mitochondrial accumulation of eIF5A

Miyake, T., Pradeep, S., Wu, S., Rupaimoole, R., Zand, B., Wen, Y., Gharpure, K. M., Nagaraja, A. S., Hu, W., Cho, M. S., Dalton, H. J., Previs, R. A., Taylor, M. L., Hisamatsu, T., Kang, Y., Liu, T., Shacham, S., McCauley, D., Hawke, D. H., Wiktorowicz, J. E. & 2 others, Coleman, R. & Sood, A. K., Jul 15 2015, In : Clinical Cancer Research. 21, 14, p. 3286-3297 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Topotecan
Mitochondria
Cell Death
Neoplasms
2014
10 Citations (Scopus)

Biologic effects of platelet-derived growth factor receptor a blockade in uterine cancer

Roh, J. W., Huang, J., Hu, W., Yang, X., Jennings, N. B., Sehgal, V., Sohn, B. H., Han, H. D., Lee, S. J., Thanapprapasr, D., Bottsford-Miller, J., Zand, B., Dalton, H. J., Previs, R. A., Davis, A. N., Matsuo, K., Lee, J-S., Ram, P., Coleman, R. & Sood, A. K., May 15 2014, In : Clinical Cancer Research. 20, 10, p. 2740-2750 11 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Uterine Neoplasms
Cell Survival
Apoptosis
Therapeutics
14 Citations (Scopus)

Clodronate inhibits tumor angiogenesis in mouse models of ovarian cancer

Reusser, N. M., Dalton, H. J., Pradeep, S., Gonzalez-Villasana, V., Jennings, N. B., Vasquez, H. G., Wen, Y., Rupaimoole, R., Nagaraja, A. S., Gharpure, K., Miyake, T., Huang, J., Hu, W., Lopez, G. & Sood, A. K., Jan 1 2014, In : Cancer Biology and Therapy. 15, 8, p. 1061-1067 7 p.

Research output: Contribution to journalArticle

Clodronic Acid
Ovarian Neoplasms
Macrophages
Neoplasms
Diphosphonates
13 Citations (Scopus)

Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to dasatinib

Huang, J., Hu, W., Bottsford-Miller, J., Liu, T., Han, H. D., Zand, B., Pradeep, S., Roh, J. W., Thanapprapasr, D., Dalton, H. J., Pecot, C. V., Rupaimoole, R., Lu, C., Fellman, B., Urbauer, D., Kang, Y., Jennings, N. B., Huang, L., Deavers, M. T., Broaddus, R. & 2 others, Coleman, R. & Sood, A. K., Apr 1 2014, In : Clinical Cancer Research. 20, 7, p. 1846-1855 10 p.

Research output: Contribution to journalArticle

Uterine Neoplasms
Mitogen-Activated Protein Kinases
Protein Array Analysis
Dasatinib
Immunoprecipitation
20 Citations (Scopus)

Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes

Tamir, A., Jag, U., Sarojini, S., Schindewolf, C., Tanaka, T., Gharbaran, R., Patel, H., Sood, A. K., Hu, W., Patwa, R., Blake, P., Chirina, P., Jeong, J. O., Lim, H., Goy, A., Pecora, A. & Suh, K. S., Jan 1 2014, In : Journal of Ovarian Research. 7, 1, 109.

Research output: Contribution to journalArticle

Kallikreins
Ovarian Neoplasms
Peptide Hydrolases
Biomarkers
Proteins
34 Citations (Scopus)

Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancer

Tucker, S. L., Gharpure, K., Herbrich, S. M., Unruh, A. K., Nick, A. M., Crane, E. K., Coleman, R., Guenthoer, J., Dalton, H. J., Wu, S. Y., Rupaimoole, R., Lopez, G., Ozpolat, B., Ivan, C., Hu, W., Baggerly, K. A. & Sood, A. K., Jun 15 2014, In : Clinical Cancer Research. 20, 12, p. 3280-3288 9 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Biomarkers
Genes
Polymerase Chain Reaction
Gene Expression
29 Citations (Scopus)

Notch3 pathway alterations in ovarian cancer

Hu, W., Liu, T., Ivan, C., Sun, Y., Huang, J., Mangala, L. S., Miyake, T., Dalton, H. J., Pradeep, S., Rupaimoole, R., Previs, R. A., Han, H. D., Bottsford-Miller, J., Zand, B., Kang, Y., Pecot, C. V., Nick, A. M., Wu, S., Lee, J-S., Sehgal, V. & 7 others, Ram, P., Liu, J., Tucker, S. L., Lopez, G., Baggerly, K. A., Coleman, R. & Sood, A. K., Jun 15 2014, In : Cancer Research. 74, 12, p. 3282-3293 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Dynamins
Growth
Endocytosis
Up-Regulation
17 Citations (Scopus)

Randomised phase II study of docetaxel plus vandetanib versus docetaxel followed by vandetanib in patients with persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: SWOG S0904

Coleman, R., Moon, J., Sood, A. K., Hu, W., Delmore, J. E., Bonebrake, A. J., Anderson, G. L., Chambers, S. K. & Markman, M., Jan 1 2014, In : European Journal of Cancer. 50, 9, p. 1638-1648 11 p.

Research output: Contribution to journalArticle

docetaxel
Fallopian Tubes
Carcinoma
Disease-Free Survival
Ovarian Neoplasms
2013
18 Citations (Scopus)

A phase II evaluation of motesanib (AMG 706) in the treatment of persistent or recurrent ovarian, fallopian tube and primary peritoneal carcinomas: A Gynecologic Oncology Group study

Schilder, R. J., Sill, M. W., Lankes, H. A., Gold, M. A., Mannel, R. S., Modesitt, S. C., Hanjani, P., Bonebrake, A. J., Sood, A. K., Godwin, A. K., Hu, W. & Alpaugh, R. K., Apr 1 2013, In : Gynecologic oncology. 129, 1, p. 86-91 6 p.

Research output: Contribution to journalArticle

Fallopian Tubes
Carcinoma
Vascular Endothelial Growth Factors
Therapeutics
Ovarian Neoplasms
12 Citations (Scopus)

Enhanced cytotoxic effects of combined valproic acid and the Aurora kinase inhibitor VE465 on gynecologic cancer cells

Li, Y., Liu, T., Ivan, C., Huang, J., Shen, D. Y., Kavanagh, J. J., Bast Jr, R. C., Fu, S., Hu, W. & Sood, A. K., Jan 1 2013, In : Frontiers in Oncology. 3 MAR, Article 00058.

Research output: Contribution to journalArticle

Aurora Kinases
Valproic Acid
Neoplasms
Ovarian Neoplasms
Histone Deacetylase Inhibitors
20 Citations (Scopus)

Epigenetic analysis of the Notch superfamily in high-grade serous ovarian cancer

Ivan, C., Hu, W., Bottsford-Miller, J., Zand, B., Dalton, H. J., Liu, T., Huang, J., Nick, A. M., Lopez, G., Coleman, R., Baggerly, K. A. & Sood, A. K., Mar 1 2013, In : Gynecologic oncology. 128, 3, p. 506-511 6 p.

Research output: Contribution to journalArticle

Epigenomics
Ovarian Neoplasms
MicroRNAs
Methylation
Survival
28 Citations (Scopus)

Methylation and histone deacetylase inhibition in combination with platinum treatment in patients with advanced malignancies

Falchook, G. S., Fu, S., Naing, A., Hong, D. S., Hu, W., Moulder, S., Wheler, J. J., Sood, A. K., Bustinza-Linares, E., Parkhurst, K. L. & Kurzrock, R., Oct 1 2013, In : Investigational New Drugs. 31, 5, p. 1192-1200 9 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Platinum
Methylation
Azacitidine
Carboplatin
17 Citations (Scopus)

Reduced expression of Snail decreases breast cancer cell motility by downregulating the expression and inhibiting the activity of RhoA GTPase

Zhang, A., Wang, Q., Han, Z., Hu, W., Xi, L., Gao, Q., Wang, S., Zhou, J., Xu, G., Meng, L., Chen, G. & Ma, D., Aug 1 2013, In : Oncology Letters. 6, 2, p. 339-346 8 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Cell Movement
Down-Regulation
Breast Neoplasms
Matrix Metalloproteinases
73 Citations (Scopus)

Role of focal adhesion kinase in regulating YB-1-Mediated paclitaxel resistance in ovarian cancer

Kang, Y., Hu, W., Ivan, C., Dalton, H. J., Miyake, T., Pecot, C. V., Zand, B., Liu, T., Huang, J., Jennings, N. B., Rupaimoole, R., Taylor, M., Pradeep, S., Wu, S., Lu, C., Wen, Y., Huang, J., Liu, J. & Sood, A. K., Oct 2 2013, In : Journal of the National Cancer Institute. 105, 19, p. 1485-1495 11 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Paclitaxel
Ovarian Neoplasms
Focal Adhesion Kinase 1
Protein Array Analysis
15 Citations (Scopus)

Targeting Src and tubulin in mucinous ovarian carcinoma

Liu, T., Hu, W., Dalton, H. J., Choi, H. J., Huang, J., Kang, Y., Pradeep, S., Miyake, T., Song, J. H., Wen, Y., Lu, C., Pecot, C. V., Bottsford-Miller, J., Zand, B., Jennings, N. B., Ivan, C., Gallick, G. E., Baggerly, K. A., Hangauer, D. G., Coleman, R. & 2 others, Frumovitz, M. & Sood, A. K., Dec 1 2013, In : Clinical Cancer Research. 19, 23, p. 6532-6543 12 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Tubulin
oxaliplatin
Ovarian Neoplasms
Cell Proliferation
2012
56 Citations (Scopus)

A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: A Gynecologic Oncology Group study

Coleman, R., Sill, M. W., Lankes, H. A., Fader, A. N., Finkler, N. J., Hoffman, J. S., Rose, P. G., Sutton, G. P., Drescher, C. W., McMeekin, D. S., Hu, W., Deavers, M., Godwin, A. K., Alpaugh, R. K. & Sood, A. K., Dec 1 2012, In : Gynecologic oncology. 127, 3, p. 538-543 6 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Disease-Free Survival
Therapeutics
aflibercept
Fibroblast Growth Factor 1
5 Citations (Scopus)

Aurora kinase inhibitor VE 465 synergistically enhances cytotoxicity of carboplatin in ovarian cancer cells through induction of apoptosis and downregulation of histone 3

Fu, S., Li, Y., Huang, J., Liu, T., Hong, Z., Chen, A., Bast Jr, R. C., Kavanagh, J. J., Gershenson, D. M., Sood, A. K. & Hu, W., Sep 1 2012, In : Cancer Biology and Therapy. 13, 11, p. 1034-1041 8 p.

Research output: Contribution to journalArticle

Aurora Kinases
Carboplatin
Ovarian Neoplasms
Histones
Down-Regulation
28 Citations (Scopus)

Metronomic activity of CD44-targeted hyaluronic acid-paclitaxel in ovarian carcinoma

Lee, S. J., Ghosh, S. C., Han, H. D., Stone, R. L., Bottsford-Miller, J., Shen, D. Y., Auzenne, E. J., Lopez-Araujo, A., Lu, C., Nishimura, M., Pecot, C. V., Zand, B., Thanapprapasr, D., Jennings, N. B., Kang, Y., Huang, J., Hu, W., Klostergaard, J. & Sood, A. K., Aug 1 2012, In : Clinical Cancer Research. 18, 15, p. 4114-4121 8 p.

Research output: Contribution to journalArticle

Maximum Tolerated Dose
Hyaluronic Acid
Paclitaxel
Carcinoma
Tumor Burden
356 Citations (Scopus)

Paraneoplastic thrombocytosis in ovarian cancer

Stone, R. L., Nick, A. M., McNeish, I. A., Balkwill, F., Han, H. D., Bottsford-Miller, J., Rupaimoole, R., Armaiz-Pena, G. N., Pecot, C. V., Coward, J., Deavers, M. T., Vasquez, H. G., Urbauer, D., Landen, C. N., Hu, W., Gershenson, H., Matsuo, K., Shahzad, M. M. K., King, E. R., Tekedereli, I. & 14 others, Ozpolat, B., Ahn, E. H., Bond, V. K., Wang, R., Drew, A. F., Gushiken, F., Lamkin, D., Collins, K., DeGeest, K., Lutgendorf, S. K., Chiu, W., Lopez, G., Afshar-Kharghan, V. & Sood, A. K., Feb 16 2012, In : New England Journal of Medicine. 366, 7, p. 610-618 9 p.

Research output: Contribution to journalArticle

Thrombocytosis
Ovarian Neoplasms
Thrombopoietin
Interleukin-6
Neoplasms
37 Citations (Scopus)

Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: A gynecologic oncology group study

Schilder, R. J., Brady, W. E., Lankes, H. A., Fiorica, J. V., Shahin, M. S., Zhou, X. C., Mannel, R. S., Pathak, H. B., Hu, W., Alpaugh, R. K., Sood, A. K. & Godwin, A. K., Oct 1 2012, In : Gynecologic oncology. 127, 1, p. 70-74 5 p.

Research output: Contribution to journalArticle

Carcinoma
Biomarkers
Disease-Free Survival
Circulating Neoplastic Cells
Proto-Oncogenes
2011
61 Citations (Scopus)

Biological roles of the delta family notch ligand Dll4 in tumor and endothelial cells in ovarian cancer

Hu, W., Lu, C., Han, H. D., Huang, J., Shen, D. Y., Stone, R. L., Nick, A. M., Shahzad, M. M. K., Mora, E., Jennings, N. B., Lee, S. J., Roh, J. W., Matsuo, K., Nishimura, M., Goodman, B. W., Jaffe, R. B., Langley, R. R., Deavers, M. T., Lopez, G., Coleman, R. & 1 others, Sood, A. K., Sep 15 2011, In : Cancer Research. 71, 18, p. 6030-6039 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Endothelial Cells
Ligands
Neoplasms
Vascular Endothelial Growth Factor A
61 Citations (Scopus)

Distinctive DNA methylation patterns of cell-free plasma DNA in women with malignant ovarian tumors

Liggett, T. E., Melnikov, A., Yi, Q., Replogle, C., Hu, W., Rotmensch, J., Kamat, A., Sood, A. K. & Levenson, V., Jan 1 2011, In : Gynecologic oncology. 120, 1, p. 113-120 8 p.

Research output: Contribution to journalArticle

DNA Methylation
Plasma Cells
Methylation
Carcinoma
DNA
100 Citations (Scopus)

Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancer

Fu, S., Hu, W., Iyer, R. B., Kavanagh, J. J., Coleman, R., Levenback, C. F., Sood, A. K., Wolf, J. K., Gershenson, D. M., Markman, M., Hennessy, B. T., Kurzrock, R. & Bast Jr, R. C., Apr 15 2011, In : Cancer. 117, 8, p. 1661-1669 9 p.

Research output: Contribution to journalArticle

Azacitidine
Platinum
Carboplatin
Disease-Free Survival
Ovarian epithelial cancer
2010
148 Citations (Scopus)

Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis

Sood, A. K., Armaiz-Pena, G. N., Halder, J., Nick, A. M., Stone, R. L., Hu, W., Carroll, A. R., Spannuth, W. A., Deavers, M. T., Allen, J. K., Han, L. Y., Kamat, A. A., Shahzad, M. M. K., McIntyre, B. W., Diaz-Montero, C. M., Jennings, N. B., Lin, Y. G., Merritt, W. M., DeGeest, K., Vivas-Mejia, P. E. & 4 others, Lopez, G., Schaller, M. D., Cole, S. W. & Lutgendorf, S. K., May 3 2010, In : Journal of Clinical Investigation. 120, 5, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

Anoikis
Focal Adhesion Protein-Tyrosine Kinases
Adrenergic Agents
Ovarian Neoplasms
Epinephrine
49 Citations (Scopus)

Microenvironment and Pathogenesis of Epithelial Ovarian Cancer

Saad, A. F., Hu, W. & Sood, A. K., Dec 1 2010, In : Hormones and Cancer. 1, 6, p. 277-290 14 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Neoplasm Metastasis
Mutation
Fallopian Tubes
13 Citations (Scopus)

Prognostic biomarkers in ovarian cancer

Huang, J., Hu, W. & Sood, A. K., Dec 1 2010, In : Cancer Biomarkers. 8, 4-5, p. 231-251 21 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Biomarkers
Tumor Biomarkers
Research Personnel
Neoplasms