Xiaojun Liu

Assistant Professor

  • 262 Citations
  • 11 h-Index
19952018
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Fingerprint Dive into the research topics where Xiaojun Liu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Nucleosides Medicine & Life Sciences
Ataxia Telangiectasia Medicine & Life Sciences
DNA-Activated Protein Kinase Medicine & Life Sciences
Homologous Recombination Medicine & Life Sciences
DNA Breaks Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
DNA Medicine & Life Sciences
Drug Combinations Medicine & Life Sciences

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Research Output 1995 2018

  • 262 Citations
  • 11 h-Index
  • 18 Article
2 Citations (Scopus)

Targeting BRCA1/2 deficient ovarian cancer with CNDAC-based drug combinations

Liu, X., Jiang, Y., Nowak, B., Qiang, B., Cheng, N., Chen, Y. & Plunkett Jr, W. K., Feb 1 2018, In : Cancer chemotherapy and pharmacology. 81, 2, p. 255-267 13 p.

Research output: Contribution to journalArticle

Cytosine
Drug Combinations
Ovarian Neoplasms
Taxoids
oxaliplatin
7 Citations (Scopus)

TDP1 is critical for the repair of DNA breaks induced by sapacitabine, a nucleoside also targeting ATM- and BRCA-deficient tumors

Al Abo, M., Sasanuma, H., Liu, X., Rajapakse, V. N., Huang, S. Y., Kiselev, E., Takeda, S., Plunkett Jr, W. K. & Pommier, Y., Nov 1 2017, In : Molecular cancer therapeutics. 16, 11, p. 2543-2551 9 p.

Research output: Contribution to journalArticle

DNA Breaks
Nucleosides
Camptothecin
Neoplasms
Cytarabine
3 Citations (Scopus)
Ataxia Telangiectasia
B-Cell Chronic Lymphocytic Leukemia
Mutation
Genes
Chromosomes, Human, Pair 1
2 Citations (Scopus)

Mechanism-based drug combinations with the DNA strand-breaking nucleoside analog CNDAC

Liu, X., Jiang, Y., Nowak, B., Hargis, S. & Plunkett Jr, W. K., Oct 1 2016, In : Molecular cancer therapeutics. 15, 10, p. 2302-2313 12 p.

Research output: Contribution to journalArticle

Drug Combinations
Nucleosides
DNA
DNA Repair
Homologous Recombination
14 Citations (Scopus)

Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks

Liu, X., Nowak, B., Wang, Y. Q. & Plunkett Jr, W. K., Jun 26 2012, In : Chinese journal of cancer. 31, 8, p. 373-380 8 p.

Research output: Contribution to journalArticle

gemcitabine
DNA Breaks
Cytarabine
Prodrugs
Nucleosides