• 2258 Citations
  • 27 h-Index
20042019
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  • 10 Similar Profiles
Clinical Trials Mathematics
Dose Finding Mathematics
Dose Mathematics
Toxicity Mathematics
Clinical Trials, Phase I Medicine & Life Sciences
Phase I Trial Mathematics
Phase II Clinical Trials Medicine & Life Sciences
Continual Reassessment Method Mathematics

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Research Output 2004 2019

A dose finding design for seizure reduction in neonates

Ursino, M., Yuan, Y., Alberti, C., Comets, E., Favrais, G., Friede, T., Lentz, F., Stallard, N. & Zohar, S., Feb 1 2019, In : Journal of the Royal Statistical Society. Series C: Applied Statistics. 68, 2, p. 427-444 18 p.

Research output: Contribution to journalArticle

Dose Finding
Toxicity
Efficacy
Weighted Likelihood
Logistic Model

Bayesian analysis of longitudinal dyadic data with informative missing data using a dyadic shared-parameter model

Ahn, J., Morita, S., Wang, W. & Yuan, Y., Jan 1 2019, In : Statistical Methods in Medical Research. 28, 1, p. 70-83 14 p.

Research output: Contribution to journalArticle

Bayes Theorem
Bayesian Analysis
Missing Data
Missing Data Mechanism
Longitudinal Studies
2 Citations

gBOIN: a unified model-assisted phase I trial design accounting for toxicity grades, and binary or continuous end points

Mu, R., Yuan, Y., Xu, J., Mandrekar, S. J. & Yin, J., Feb 1 2019, In : Journal of the Royal Statistical Society. Series C: Applied Statistics. 68, 2, p. 289-308 20 p.

Research output: Contribution to journalArticle

Phase I Trial
End point
Toxicity
Dose
Binary

Latent Class Dynamic Mediation Model with Application to Smoking Cessation Data

Huang, J., Yuan, Y. & Wetter, D., Jan 1 2019, (Accepted/In press) In : Psychometrika.

Research output: Contribution to journalArticle

Latent Class
Mediation
Smoking
Smoking Cessation
Dynamic models

Preface to the themed issue on ‘Early phase clinical trial design methodology’

Wages, N. A. & Yuan, Y., Feb 1 2019, In : Journal of the Royal Statistical Society. Series C: Applied Statistics. 68, 2, p. 267-269 3 p.

Research output: Contribution to journalArticle

Clinical Trials
Design Methodology
Clinical trials
Design methodology