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20022024

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  • Article

    Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

    Ceccarelli, M., Barthel, F. P., Malta, T. M., Sabedot, T. S., Salama, S. R., Murray, B. A., Morozova, O., Newton, Y., Radenbaugh, A., Pagnotta, S. M., Anjum, S., Wang, J., Manyam, G., Zoppoli, P., Ling, S., Rao, A. A., Grifford, M., Cherniack, A. D., Zhang, H., Poisson, L., & 188 othersCarlotti, C. G., Tirapelli, D. P. D. C., Rao, A., Mikkelsen, T., Lau, C. C., Yung, W. K. A., Rabadan, R., Huse, J., Brat, D. J., Lehman, N. L., Barnholtz-Sloan, J. S., Zheng, S., Hess, K., Rao, G., Meyerson, M., Beroukhim, R., Cooper, L., Akbani, R., Wrensch, M., Haussler, D., Aldape, K. D., Laird, P. W., Gutmann, D. H., Noushmehr, H., Arachchi, H., Auman, J. T., Balasundaram, M., Balu, S., Barnett, G., Baylin, S., Bell, S., Benz, C., Bir, N., Black, K. L., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Bristow, C. A., Butterfield, Y. S. N., Chen, Q. R., Chin, L., Cho, J., Chuah, E., Chudamani, S., Coetzee, S. G., Cohen, M. L., Colman, H., Couce, M., D'Angelo, F., Davidsen, T., Davis, A., Demchok, J. A., Devine, K., Ding, L., Duell, R., Elder, J. B., Eschbacher, J. M., Fehrenbach, A., Ferguson, M., Frazer, S., Fuller, G., Fulop, J., Gabriel, S. B., Garofano, L., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Giannini, C., Gibson, W. J., Hadjipanayis, A., Hayes, D. N., Heiman, D. I., Hermes, B., Hilty, J., Hoadley, K. A., Hoyle, A. P., Huang, M., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Ju, Z., Kastl, A., Kendler, A., Kim, J., Kucherlapati, R., Lai, P. H., Lawrence, M. S., Lee, S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Liu, Y., Liu, J., Ljubimova, J. Y., Lu, Y., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., McGraw, M., McPherson, C., Meng, S., Mieczkowski, P. A., Miller, C. R., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Naresh, R., Naska, T., Neder, L., Noble, M. S., Noss, A., O'Neill, B. P., Ostrom, Q. T., Palmer, C., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pierson, C. R., Pihl, T., Protopopov, A., Radenbaugh, A., Ramirez, N. C., Rathmell, W. K., Ren, X., Roach, J., Robertson, A. G., Saksena, G., Schein, J. E., Schumacher, S. E., Seidman, J., Senecal, K., Seth, S., Shen, H., Shi, Y., Shih, J., Shimmel, K., Sicotte, H., Sifri, S., Silva, T., Simons, J. V., Singh, R., Skelly, T., Sloan, A. E., Sofia, H. J., Soloway, M. G., Song, X., Sougnez, C., Souza, C., Staugaitis, S. M., Sun, H., Sun, C., Tan, D., Tang, J., Tang, Y., Thorne, L., Trevisan, F. A., Triche, T., Van Den Berg, D. J., Veluvolu, U., Voet, D., Wan, Y., Wang, Z., Warnick, R., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Williams, F., Wise, L., Wolinsky, Y., Wu, J., Xu, A. W., Yang, L., Yang, L., Zack, T. I., Zenklusen, J. C., Zhang, J., Zhang, W., Zhang, J., Zmuda, E., Noushmehr, H., Iavarone, A. & Verhaak, R. G. W., Jan 28 2016, In: Cell. 164, 3, p. 550-563 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1446 Scopus citations
  • Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

    The Cancer Genome Atlas Research Network, Aug 14 2014, In: Cell. 158, 4, p. 929-944 16 p.

    Research output: Contribution to journalArticlepeer-review

    1093 Scopus citations
  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 321-337.e10

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1748 Scopus citations
  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    The Cancer Genome Atlas Network, Mar 28 2018, In: Cell Systems. 6, 3, p. 282-300.e2

    Research output: Contribution to journalArticlepeer-review

    Open Access
    240 Scopus citations
  • Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 297-312.e12

    Research output: Contribution to journalArticlepeer-review

    Open Access
    189 Scopus citations
  • Pan-cancer clinical and molecular analysis of racial disparities

    Lara, O. D., Wang, Y., Asare, A., Xu, T., Chiu, H. S., Liu, Y., Hu, W., Sumazin, P., Uppal, S., Zhang, L., Rauh-Hain, J. A. & Sood, A. K., Feb 15 2020, In: Cancer. 126, 4, p. 800-807 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Pathogenic Germline Variants in 10,389 Adult Cancers

    The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 355-370.e14

    Research output: Contribution to journalArticlepeer-review

    Open Access
    507 Scopus citations
  • Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

    The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 305-320.e10

    Research output: Contribution to journalArticlepeer-review

    Open Access
    218 Scopus citations
  • Predicting high-risk endometrioid carcinomas using proteins

    Du, D., Ma, W., Yates, M. S., Chen, T., Lu, K. H., Lu, Y., Weinstein, J. N., Broaddus, R. R., Mills, G. B. & Liu, Y., Apr 13 2018, In: Oncotarget. 9, 28, p. 19704-19715 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Open Access
    1 Scopus citations
  • Regulatory MiR-148a-ACVR1/BMP circuit defines a cancer stem cell-like aggressive subtype of hepatocellular carcinoma

    Li, L., Liu, Y., Guo, Y., Liu, B., Zhao, Y., Li, P., Song, F., Zheng, H., Yu, J., Song, T., Niu, R., Li, Q., Wang, X. W., Zhang, W. & Chen, K., Feb 1 2015, In: Hepatology. 61, 2, p. 574-584 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    75 Scopus citations
  • Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

    MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In: Cell Systems. 6, 3, p. 271-281.e7

    Research output: Contribution to journalArticlepeer-review

    Open Access
    446 Scopus citations
  • Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 282-296.e4

    Research output: Contribution to journalArticlepeer-review

    Open Access
    268 Scopus citations
  • Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 181-193.e7

    Research output: Contribution to journalArticlepeer-review

    Open Access
    585 Scopus citations
  • Survival correlation of immune response in human cancers

    Liu, Y., 2019, In: Oncotarget. 10, 64, p. 6885-6897 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Systematic Analysis of Splice-Site-Creating Mutations in Cancer

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 270-281.e3

    Research output: Contribution to journalArticlepeer-review

    Open Access
    159 Scopus citations
  • The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 313-326.e5

    Research output: Contribution to journalArticlepeer-review

    Open Access
    514 Scopus citations
  • The cancer genome atlas pan-cancer analysis project

    Weinstein, J. N., Collisson, E. A., Mills, G. B., Shaw, K. R. M., Ozenberger, B. A., Ellrott, K., Sander, C., Stuart, J. M., Chang, K., Creighton, C. J., Davis, C., Donehower, L., Drummond, J., Wheeler, D., Ally, A., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chu, A., Chuah, E., & 316 othersChun, H. J. E., Dhalla, N., Guin, R., Hirst, M., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Robertson, A. G., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Varhol, R. J., Beroukhim, R., Bhatt, A. S., Brooks, A. N., Cherniack, A. D., Freeman, S. S., Gabriel, S. B., Helman, E., Jung, J., Meyerson, M., Ojesina, A. I., Pedamallu, C. S., Saksena, G., Schumacher, S. E., Tabak, B., Zack, T., Lander, E. S., Bristow, C. A., Hadjipanayis, A., Haseley, P., Kucherlapati, R., Lee, S., Lee, E., Luquette, L. J., Mahadeshwar, H. S., Pantazi, A., Parfenov, M., Park, P. J., Protopopov, A., Ren, X., Santoso, N., Seidman, J., Seth, S., Song, X., Tang, J., Xi, R., Xu, A. W., Yang, L., Zeng, D., Auman, J. T., Balu, S., Buda, E., Fan, C., Hoadley, K. A., Jones, C. D., Meng, S., Mieczkowski, P. A., Parker, J. S., Perou, C. M., Roach, J., Shi, Y., Silva, G. O., Tan, D., Veluvolu, U., Waring, S., Wilkerson, M. D., Wu, J., Zhao, W., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jeffreys, S. R., Mose, L. E., Simons, J. V., Soloway, M. G., Baylin, S. B., Berman, B. P., Bootwalla, M. S., Danilova, L., Herman, J. G., Hinoue, T., Laird, P. W., Rhie, S. K., Shen, H., Triche, T., Weisenberger, D. J., Carter, S. L., Cibulskis, K., Chin, L., Zhang, J., Sougnez, C., Wang, M., Getz, G., Dinh, H., Doddapaneni, H. V., Gibbs, R., Gunaratne, P., Han, Y., Kalra, D., Kovar, C., Lewis, L., Morgan, M., Morton, D., Muzny, D., Reid, J., Xi, L., Cho, J., Dicara, D., Frazer, S., Gehlenborg, N., Heiman, D. I., Kim, J., Lawrence, M. S., Lin, P., Liu, Y., Noble, M. S., Stojanov, P., Voet, D., Zhang, H., Zou, L., Stewart, C., Bernard, B., Bressler, R., Eakin, A., Iype, L., Knijnenburg, T., Kramer, R., Kreisberg, R., Leinonen, K., Lin, J., Liu, Y., Miller, M., Reynolds, S. M., Rovira, H., Shmulevich, I., Thorsson, V., Yang, D., Zhang, W., Amin, S., Wu, C. J., Wu, C. C., Akbani, R., Aldape, K., Baggerly, K. A., Broom, B., Casasent, T. D., Cleland, J., Dodda, D., Edgerton, M., Han, L., Herbrich, S. M., Ju, Z., Kim, H., Lerner, S., Li, J., Liang, H., Liu, W., Lorenzi, P. L., Lu, Y., Melott, J., Nguyen, L., Su, X., Verhaak, R., Wang, W., Wong, A., Yang, Y., Yao, J., Yao, R., Yoshihara, K., Yuan, Y., Yung, A. K., Zhang, N., Zheng, S., Ryan, M., Kane, D. W., Aksoy, B. A., Ciriello, G., Dresdner, G., Gao, J., Gross, B., Jacobsen, A., Kahles, A., Ladanyi, M., Lee, W., Lehmann, K. V., Miller, M. L., Ramirez, R., Rätsch, G., Reva, B., Schultz, N., Senbabaoglu, Y., Shen, R., Sinha, R., Sumer, S. O., Sun, Y., Taylor, B. S., Weinhold, N., Fei, S., Spellman, P., Benz, C., Carlin, D., Cline, M., Craft, B., Goldman, M., Haussler, D., Ma, S., Ng, S., Paull, E., Radenbaugh, A., Salama, S., Sokolov, A., Swatloski, T., Uzunangelov, V., Waltman, P., Yau, C., Zhu, J., Hamilton, S. R., Abbott, S., Abbott, R., Dees, N. D., Delehaunty, K., Ding, L., Dooling, D. J., Eldred, J. M., Fronick, C. C., Fulton, R., Fulton, L. L., Kalicki-Veizer, J., Kanchi, K. L., Kandoth, C., Koboldt, D. C., Larson, D. E., Ley, T. J., Lin, L., Lu, C., Magrini, V. J., Mardis, E. R., McLellan, M. D., McMichael, J. F., Miller, C. A., O'Laughlin, M., Pohl, C., Schmidt, H., Smith, S. M., Walker, J., Wallis, J. W., Wendl, M. C., Wilson, R. K., Wylie, T., Zhang, Q., Burton, R., Jensen, M. A., Kahn, A., Pihl, T., Pot, D., Wan, Y., Levine, D. A., Black, A. D., Bowen, J., Frick, J., Gastier-Foster, J. M., Harper, H. A., Helsel, C., Leraas, K. M., Lichtenberg, T. M., McAllister, C., Ramirez, N. C., Sharpe, S., Wise, L., Zmuda, E., Chanock, S. J., Davidsen, T., Demchok, J. A., Eley, G., Felau, I., Sheth, M., Sofia, H., Staudt, L., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Omberg, L., Margolin, A., Raphael, B. J., Vandin, F., Wu, H. T., Leiserson, M. D. M., Benz, S. C., Vaske, C. J., Noushmehr, H., Wolf, D., Veer, L. V. T., Anastassiou, D., Yang, T. H. O., Lopez-Bigas, N., Gonzalez-Perez, A., Tamborero, D., Xia, Z., Li, W., Cho, D. Y., Przytycka, T., Hamilton, M., McGuire, S., Nelander, S., Johansson, P., Jörnsten, R. & Kling, T., Oct 1 2013, In: Nature Genetics. 45, 10, p. 1113-1120 8 p.

    Research output: Contribution to journalArticlepeer-review

    5099 Scopus citations
  • The Immune Landscape of Cancer

    The Cancer Genome Atlas Research Network, Apr 17 2018, In: Immunity. 48, 4, p. 812-830.e14

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3139 Scopus citations
  • The somatic genomic landscape of glioblastoma

    TCGA Research Network, Oct 10 2013, In: Cell. 155, 2, p. 462 1 p.

    Research output: Contribution to journalArticlepeer-review

    3492 Scopus citations
  • Transcriptome and small RNA deep sequencing reveals deregulation of miRNA biogenesis in human glioma

    Moore, L. M., Kivinen, V., Liu, Y., Annala, M., Cogdell, D., Liu, X., Liu, C. G., Sawaya, R., Yli-Harja, O., Shmulevich, I., Fuller, G. N., Zhang, W. & Nykter, M., Feb 2013, In: Journal of Pathology. 229, 3, p. 449-459 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • Tumor-associated methylation of the putative tumor suppressor ajap1 gene and association between decreased ajap1 expression and shorter survival in patients with glioma

    Cogdell, D., Chung, W., Liu, Y., Matthew McDonald, J., Aldape, K., Issa, J. P. J., Fuller, G. N. & Zhang, W., 2011, In: Chinese Journal of Cancer. 30, 4, p. 254-263 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Tumour angiogenesis regulation by the miR-200 family

    Pecot, C. V., Rupaimoole, R., Yang, D., Akbani, R., Ivan, C., Lu, C., Wu, S., Han, H. D., Shah, M. Y., Rodriguez-Aguayo, C., Bottsford-Miller, J., Liu, Y., Kim, S. B., Unruh, A., Gonzalez-Villasana, V., Huang, L., Zand, B., Moreno-Smith, M., Mangala, L. S., Taylor, M., & 17 othersDalton, H. J., Sehgal, V., Wen, Y., Kang, Y., Baggerly, K. A., Lee, J. S., Ram, P. T., Ravoori, M. K., Kundra, V., Zhang, X., Ali-Fehmi, R., Gonzalez-Angulo, A. M., Massion, P. P., Calin, G. A., Lopez-Berestein, G., Zhang, W. & Sood, A. K., Sep 10 2013, In: Nature communications. 4, 2427.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    340 Scopus citations
  • Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

    Li, X., Liu, Y., Granberg, K. J., Wang, Q., Moore, L. M., Ji, P., Gumin, J., Sulman, E. P., Calin, G. A., Haapasalo, H., Nykter, M., Shmulevich, I., Fuller, G. N., Lang, F. F. & Zhang, W., Mar 26 2015, In: Oncogene. 34, 13, p. 1619-1628 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    79 Scopus citations
  • Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway

    TCGA Research Network, Feb 2 2021, In: Cell Reports. 34, 5, 108707.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations