• 8473 Citations
  • 41 h-Index
1981 …2019
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Research Output 1981 2019

  • 8473 Citations
  • 41 h-Index
  • 171 Article
  • 8 Review article
  • 1 Letter
  • 1 Short survey
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Article
2019

Cerebrospinal pharmacokinetic and pharmacodynamic analysis of efficacy of meropenem in paediatric patients with bacterial meningitis

Ohata, Y., Tomita, Y., Sunakawa, K., Drusano, G. L. & Tanigawara, Y., Sep 1 2019, In : International Journal of Antimicrobial Agents. 54, 3, p. 292-300 9 p.

Research output: Contribution to journalArticle

meropenem
Bacterial Meningitides
Cerebrospinal Fluid
Pharmacokinetics
Pediatrics

Gefitinib exposure and occurrence of interstitial lung disease in Japanese patients with non-small-cell lung cancer

Kawata, T., Higashimori, M., Itoh, Y., Tomkinson, H., Johnson, M. G., Tang, W., Nyberg, F., Jiang, H. & Tanigawara, Y., May 1 2019, In : Cancer chemotherapy and pharmacology. 83, 5, p. 849-858 10 p.

Research output: Contribution to journalArticle

Pulmonary diseases
Interstitial Lung Diseases
Non-Small Cell Lung Carcinoma
Cells
Glycoproteins
1 Citation (Scopus)

Individualized Dosing of Axitinib Based on First-Dose Area Under the Concentration–Time Curve for Metastatic Renal-Cell Carcinoma

Miura, Y., Imamura, C. K., Uchino, K., Kishida, T., Matsubara, N., Shinojima, T., Kondo, K., Hongo, F., Yoshimura, K., Tanigawara, Y. & Takano, T., Feb 1 2019, In : Clinical Genitourinary Cancer. 17, 1, p. e1-e11

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Area Under Curve
Disease-Free Survival
Survival Rate
Confidence Intervals
2018

Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype-Guided Dosing of Tamoxifen

Nakamura, T., Toshimoto, K., Lee, W., Imamura, C. K., Tanigawara, Y. & Sugiyama, Y., Jul 2018, In : CPT: Pharmacometrics and Systems Pharmacology. 7, 7, p. 474-482 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Pharmacokinetics
Tamoxifen
Genotype
Predict
16 Citations (Scopus)

Clinical Factors Predicting Detection of T790M Mutation in Rebiopsy for EGFR-Mutant Non–small-cell Lung Cancer

Kawamura, T., Kenmotsu, H., Omori, S., Nakashima, K., Wakuda, K., Ono, A., Naito, T., Murakami, H., Omae, K., Mori, K., Tanigawara, Y., Nakajima, T., Ohde, Y., Endo, M. & Takahashi, T., Mar 1 2018, In : Clinical Lung Cancer. 19, 2, p. e247-e252

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Mutation
Recurrence
6 Citations (Scopus)

Modeling and simulation of bone mineral density in Japanese osteoporosis patients treated with zoledronic acid using tartrate-resistant acid phosphatase 5b, a bone resorption marker

Mori, Y., Kasai, H., Ose, A., Serada, M., Ishiguro, M., Shiraki, M. & Tanigawara, Y., May 1 2018, In : Osteoporosis International. 29, 5, p. 1155-1163 9 p.

Research output: Contribution to journalArticle

zoledronic acid
Bone Resorption
Bone Density
Osteoporosis
Theoretical Models

Pharmacodynamic analysis of eribulin safety in breast cancer patients using real-world postmarketing surveillance data

Kawamura, T., Kasai, H., Fermanelli, V., Takahashi, T., Sakata, Y., Matsuoka, T., Ishii, M. & Tanigawara, Y., Sep 2018, In : Cancer science. 109, 9, p. 2822-2829 8 p.

Research output: Contribution to journalArticle

eribulin
Neutrophils
Breast Neoplasms
Safety
Neutropenia
2017
5 Citations (Scopus)

Effect of everolimus on the glucose metabolic pathway in mouse skeletal muscle cells (C2C12)

Yoshida, K., Imamura, C. K., Hara, K., Mochizuki, M. & Tanigawara, Y., Aug 1 2017, In : Metabolomics. 13, 8, 98.

Research output: Contribution to journalArticle

Metabolic Networks and Pathways
Muscle Cells
Muscle
Skeletal Muscle
Cells
1 Citation (Scopus)

Population Pharmacokinetic and Exposure–Response Analysis of Weekly Teriparatide in Osteoporosis Patients

Ose, A., Serada, M., Yamashita, K., Tsurui, K. & Tanigawara, Y., Dec 1 2017, In : Journal of Clinical Pharmacology. 57, 12, p. 1545-1553 9 p.

Research output: Contribution to journalArticle

Teriparatide
Osteoporosis
Pharmacokinetics
Bone Density
Population
2 Citations (Scopus)

Population Pharmacokinetics of Diazoxide in Children with Hyperinsulinemic Hypoglycemia

Kizu, R., Nishimura, K., Sato, R., Kosaki, K., Tanaka, T., Tanigawara, Y. & Hasegawa, T., Nov 1 2017, In : Hormone Research in Paediatrics. 88, 5, p. 316-323 8 p.

Research output: Contribution to journalArticle

Diazoxide
Hypoglycemia
Pharmacokinetics
Population
Hyperglycemia
5 Citations (Scopus)

The effects of advanced age and serum α1-acid glycoprotein on docetaxel unbound exposure and dose-limiting toxicity in cancer patients

Kenmotsu, H., Imamura, C. K., Ono, A., Omori, S., Nakashima, K., Wakuda, K., Taira, T., Naito, T., Murakami, H., Takahashi, T. & Tanigawara, Y., Nov 2017, In : British journal of clinical pharmacology. 83, 11, p. 2416-2425 10 p.

Research output: Contribution to journalArticle

docetaxel
Glycoproteins
Acids
Serum
Neoplasms
2016
3 Citations (Scopus)

Development of an S-1 dosage formula based on renal function by a prospective pharmacokinetic study

Booka, E., Imamura, C. K., Takeuchi, H., Hamamoto, Y., Gomi, D., Mizukami, T., Ichiyama, T., Tateishi, K., Takahashi, T., Kawakubo, H., Soejima, K., Boku, N., Tanigawara, Y. & Kitagawa, Y., Jul 1 2016, In : Gastric Cancer. 19, 3, p. 876-886 11 p.

Research output: Contribution to journalArticle

Fluorouracil
Pharmacokinetics
Prospective Studies
Kidney
Area Under Curve
16 Citations (Scopus)

Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole

Imamura, C. K., Furihata, K., Okamoto, S. & Tanigawara, Y., Apr 1 2016, In : Journal of Clinical Pharmacology. 56, 4, p. 408-413 6 p.

Research output: Contribution to journalArticle

Tacrolimus
Cytochrome P-450 Enzyme System
Pharmacokinetics
Genotype
Cytochrome P-450 CYP3A
2014
11 Citations (Scopus)

Clinical practice guidelines for therapeutic drug monitoring of arbekacin: A consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

Okada, K., Kimura, T., Mikamo, H., Kasahara, K., Seki, M., Takakura, S., Tokimatsu, I., Ohmagari, N., Takahashi, Y., Matsumoto, K., Igarashi, M., Kobayashi, M., Hamada, Y., Mochizuki, T., Kimura, M., Nishi, Y., Tanigawara, Y. & Takesue, Y., Jan 2014, In : Journal of Infection and Chemotherapy. 20, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Drug Monitoring
Practice Guidelines
Drug Therapy
Japan
Serum
7 Citations (Scopus)

Forced expression of S100A10 reduces sensitivity to oxaliplatin in colorectal cancer cells

Suzuki, S. & Tanigawara, Y., May 9 2014, In : Proteome Science. 12, 1, 26.

Research output: Contribution to journalArticle

oxaliplatin
Fluorouracil
Colorectal Neoplasms
Cells
Annexin A2
6 Citations (Scopus)

Population PK modelling and simulation based on fluoxetine and norfluoxetine concentrations in milk: a milk concentration-based prediction model

Tanoshima, R., Bournissen, F. G. A., Tanigawara, Y., Kristensen, J. H., Taddio, A., Ilett, K. F., Begg, E. J., Wallach, I. & Ito, S., Oct 1 2014, In : British journal of clinical pharmacology. 78, 4, p. 918-928 11 p.

Research output: Contribution to journalArticle

Fluoxetine
Milk
Population
Pharmacokinetics
norfluoxetine
18 Citations (Scopus)

Sunitinib-induced severe toxicities in a japanese patient with the ABCG2 421 AA genotype

Miura, Y., Imamura, C. K., Fukunaga, K., Katsuyama, Y., Suyama, K., Okaneya, T., Mushiroda, T., Ando, Y., Takano, T. & Tanigawara, Y., Dec 16 2014, In : BMC cancer. 14, 1, 964.

Research output: Contribution to journalArticle

Genotype
sunitinib
Hand-Foot Syndrome
Vascular Endothelial Growth Factor Receptor
Pharmacogenetics
2013
4 Citations (Scopus)

Clinical and bacteriological efficacies of sitafloxacin against community-acquired pneumonia caused by Streptococcus pneumoniae: Nested cohort within a multicenter clinical trial

Fujita, J., Niki, Y., Kadota, J. I., Yanagihara, K., Kaku, M., Watanabe, A., Aoki, N., Hori, S., Tanigawara, Y., Cash, H. L. & Kohno, S., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 472-479 8 p.

Research output: Contribution to journalArticle

Streptococcus pneumoniae
Multicenter Studies
Pneumonia
Clinical Trials
Levofloxacin
12 Citations (Scopus)

Clinical dose findings of sitafloxacin treatment: Pharmacokinetic- pharmacodynamic analysis of two clinical trial results for community-acquired respiratory tract infections

Kohno, S., Niki, Y., Kadota, J. I., Yanagihara, K., Kaku, M., Watanabe, A., Aoki, N., Hori, S., Fujita, J. & Tanigawara, Y., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 486-494 9 p.

Research output: Contribution to journalArticle

Community-Acquired Infections
Respiratory Tract Infections
Pharmacokinetics
Clinical Trials
Microbial Sensitivity Tests
41 Citations (Scopus)

Pharmacogenetic determinants associated with sunitinib-induced toxicity and ethnic difference in Korean metastatic renal cell carcinoma patients

Kim, H. R., Park, H. S., Kwon, W. S., Lee, J. H., Tanigawara, Y., Lim, S. M., Kim, H. S., Shin, S. J., Ahn, J. B. & Rha, S. Y., Oct 1 2013, In : Cancer chemotherapy and pharmacology. 72, 4, p. 825-835 11 p.

Research output: Contribution to journalArticle

Hand-Foot Syndrome
Pharmacogenetics
Renal Cell Carcinoma
Toxicity
Neutropenia
12 Citations (Scopus)

Polymorphisms in the UGT1A1 gene predict adverse effects of irinotecan in the treatment of gynecologic cancer in Japanese patients

Hirasawa, A., Zama, T., Akahane, T., Nomura, H., Kataoka, F., Saito, K., Okubo, K., Tominaga, E., Makita, K., Susumu, N., Kosaki, K., Tanigawara, Y. & Aoki, D., Dec 1 2013, In : Journal of Human Genetics. 58, 12, p. 794-798 5 p.

Research output: Contribution to journalArticle

irinotecan
Glucuronosyltransferase
Uridine Diphosphate
Genes
Neoplasms
9 Citations (Scopus)

Population pharmacokinetics and pharmacodynamics of sitafloxacin in patients with community-acquired respiratory tract infections

Tanigawara, Y., Kaku, M., Totsuka, K., Tsuge, H. & Saito, A., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 5, p. 858-866 9 p.

Research output: Contribution to journalArticle

Community-Acquired Infections
Respiratory Tract Infections
Pharmacokinetics
Population
sitafloxacin
61 Citations (Scopus)

Practice guidelines for therapeutic drug monitoring of vancomycin: A consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

Matsumoto, K., Takesue, Y., Ohmagari, N., Mochizuki, T., Mikamo, H., Seki, M., Takakura, S., Tokimatsu, I., Takahashi, Y., Kasahara, K., Okada, K., Igarashi, M., Kobayashi, M., Hamada, Y., Kimura, M., Nishi, Y., Tanigawara, Y. & Kimura, T., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 365-380 16 p.

Research output: Contribution to journalArticle

Drug Monitoring
Vancomycin
Methicillin-Resistant Staphylococcus aureus
Practice Guidelines
Guidelines
54 Citations (Scopus)

Practice guidelines for therapeutic drug monitoring of voriconazole: A consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

Hamada, Y., Tokimatsu, I., Mikamo, H., Kimura, M., Seki, M., Takakura, S., Ohmagari, N., Takahashi, Y., Kasahara, K., Matsumoto, K., Okada, K., Igarashi, M., Kobayashi, M., Mochizuki, T., Nishi, Y., Tanigawara, Y., Kimura, T. & Takesue, Y., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 381-392 12 p.

Research output: Contribution to journalArticle

Drug Monitoring
Practice Guidelines
Guidelines
Drug Therapy
Voriconazole
2012
41 Citations (Scopus)

A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese

Kiyotani, K., Mushiroda, T., Tsunoda, T., Morizono, T., Hosono, N., Kubo, M., Tanigawara, Y., Imamura, C. K., Flockhart, D. A., Aki, F., Hirata, K., Takatsuka, Y., Okazaki, M., Ohsumi, S., Yamakawa, T., Sasa, M., Nakamura, Y. & Zembutsu, H., Apr 1 2012, In : Human molecular genetics. 21, 7, p. 1665-1672 8 p., ddr597.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Tamoxifen
Breast Neoplasms
Survival
Recurrence
2 Citations (Scopus)

Blood-direct InvaderPlus® as a new method for genetic testing

Hirasawa, A., Akahane, T., Tanigawara, Y. & Aoki, D., Aug 1 2012, In : Personalized Medicine. 9, 6, p. 657-663 7 p.

Research output: Contribution to journalArticle

Genetic Testing
Genetic Polymorphisms
Genes
64 Citations (Scopus)

Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients

Kiyotani, K., Mushiroda, T., Imamura, C. K., Tanigawara, Y., Hosono, N., Kubo, M., Sasa, M., Nakamura, Y. & Zembutsu, H., Jan 1 2012, In : Breast Cancer Research and Treatment. 131, 1, p. 137-145 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Tamoxifen
Genotype
Breast Neoplasms
Alleles
17 Citations (Scopus)

Expression changes in arrestin β 1 and genetic variation in catechol-O-methyltransferase are biomarkers for the response to morphine treatment in cancer patients

Matsuoka, H., Arao, T., Makimura, C., Takeda, M., Kiyota, H., Tsurutani, J., Fujita, Y., Matsumoto, K., Kimura, H., Otsuka, M., Koyama, A., Imamura, C. K., Tanigawara, Y., Yamanaka, T., Tanaka, K., Nishio, K. & Nakagawa, K., May 1 2012, In : Oncology reports. 27, 5, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

Arrestin
Catechol O-Methyltransferase
Morphine
Biomarkers
Neoplasms
17 Citations (Scopus)

Optimal dose finding of garenoxacin based on population pharmacokinetics/pharmacodynamics and Monte Carlo simulation

Tanigawara, Y., Nozawa, K. & Tsuda, H., Jan 1 2012, In : European Journal of Clinical Pharmacology. 68, 1, p. 39-53 15 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Population
Quinolones
Microbial Sensitivity Tests
Respiratory System
8 Citations (Scopus)

Pharmacokinetics of mizoribine in adult living donor liver transplantation

Shinoda, M., Tanabe, M., Kawachi, S., Ono, Y., Hayakawa, T., Iketani, O., Kojima, M., Itano, O., Obara, H., Kitago, M., Hibi, T., Matsubara, K., Shimojima, N., Fuchimoto, Y., Hoshino, K., Wakabayashi, G., Shimazu, M., Tanigawara, Y., Kuroda, T., Morikawa, Y. & 2 others, Kitajima, M. & Kitagawa, Y., Jun 1 2012, In : Transplantation Proceedings. 44, 5, p. 1329-1335 7 p.

Research output: Contribution to journalArticle

Living Donors
Liver Transplantation
Pharmacokinetics
Serum
Glomerular Filtration Rate
2011
110 Citations (Scopus)

A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures - A randomized, active comparator, double-blind study

Matsumoto, T., Ito, M., Hayashi, Y., Hirota, T., Tanigawara, Y., Sone, T., Fukunaga, M., Shiraki, M. & Nakamura, T., Oct 1 2011, In : Bone. 49, 4, p. 605-612 8 p.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Cholecalciferol
Double-Blind Method
Bone Density
Wrist
142 Citations (Scopus)

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

Watanabe, M., Horai, Y., Houten, S. M., Morimoto, K., Sugizaki, T., Arita, E., Mataki, C., Sato, H., Tanigawara, Y., Schoonjans, K., Itoh, H. & Auwerx, J., Jul 29 2011, In : Journal of Biological Chemistry. 286, 30, p. 26913-26920 8 p.

Research output: Contribution to journalArticle

Medical problems
Bile Acids and Salts
Energy Metabolism
Obesity
High Fat Diet
23 Citations (Scopus)
Thrombomodulin
Disseminated Intravascular Coagulation
Pharmacokinetics
Population
Hematocrit
13 Citations (Scopus)

Optimal dosage regimen of meropenem for pediatric patients based on pharmacokinetic/pharmacodynamic considerations

Ohata, Y., Tomita, Y., Nakayama, M., Kozuki, T., Sunakawa, K. & Tanigawara, Y., Jan 1 2011, In : Drug Metabolism And Pharmacokinetics. 26, 5, p. 523-531 9 p.

Research output: Contribution to journalArticle

meropenem
Pharmacokinetics
Pediatrics
Bacteria
Japan
9 Citations (Scopus)

Optimal treatment schedule of meropenem for adult patients with febrile neutropenia based on pharmacokinetic-pharmacodynamic analysis

Ohata, Y., Tomita, Y., Nakayama, M., Tamura, K. & Tanigawara, Y., Jan 1 2011, In : Journal of Infection and Chemotherapy. 17, 6, p. 831-841 11 p.

Research output: Contribution to journalArticle

meropenem
Febrile Neutropenia
Appointments and Schedules
Pharmacokinetics
Therapeutics
6 Citations (Scopus)

Pharmacokinetics of eldecalcitol in primary osteoporosis patients - Randomized, double-blind, multicentre, long-term phase III clinical study

Miyata, K., Abe, M., Terao, K., Kawanishi, T., Tsuji, N., Shiraki, M., Nakamura, T., Matsumoto, T. & Tanigawara, Y., Mar 2011, In : Japanese Pharmacology and Therapeutics. 39, 3, p. 299-307 9 p.

Research output: Contribution to journalArticle

Osteoporosis
Pharmacokinetics
Serum
eldecalcitol
Clinical Studies

Population pharmacokinetics and pharmacodynamics of levofloxacin following intravenous infusion for respiratory tract infection

Tanigawara, Y., Shimizu, T. & Totsuka, K., May 1 2011, In : Japanese Journal of Chemotherapy. 59, SUPPL. 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

Levofloxacin
Intravenous Infusions
Respiratory Tract Infections
Pharmacokinetics
Population
6 Citations (Scopus)

S100A10 protein expression is associated with oxaliplatin sensitivity in human colorectal cancer cells

Suzuki, S., Yamayoshi, Y., Nishimuta, A. & Tanigawara, Y., Dec 30 2011, In : Proteome Science. 9, 76.

Research output: Contribution to journalArticle

oxaliplatin
S100 Proteins
antineoplaston A10
Colorectal Neoplasms
Cells
2010
17 Citations (Scopus)

Pharmacokinetics of S-1 and CYP2A6 genotype in Japanese patients with advanced cancer

Hirose, T., Fujita, K. I., Nishimura, K., Ishida, H., Yamashita, K., Sunakawa, Y., Mizuno, K., Miwa, K., Nagashima, F., Tanigawara, Y., Adachi, M. & Sasaki, Y., Jan 1 2010, In : Oncology Reports. 24, 2, p. 529-536 8 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Genotype
Area Under Curve
Fluorouracil
Tegafur
170 Citations (Scopus)

Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients

Kiyotani, K., Mushiroda, T., Imamura, C. K., Hosono, N., Tsunoda, T., Kubo, M., Tanigawara, Y., Flockhart, D. A., Desta, Z., Skaar, T. C., Aki, F., Hirata, K., Takatsuka, Y., Okazaki, M., Ohsumi, S., Yamakawa, T., Sasa, M., Nakamura, Y. & Zembutsu, H., Mar 10 2010, In : Journal of Clinical Oncology. 28, 8, p. 1287-1293 7 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Tamoxifen
Breast Neoplasms
Alleles
Therapeutics
2009
14 Citations (Scopus)

A pharmacokinetic and dose escalation study of pegfilgrastim (KRN125) in lung cancer patients with chemotherapy-induced neutropenia

Yamamoto, N., Sekine, I., Nakagawa, K., Takada, M., Fukuoka, M., Tanigawara, Y. & Saijo, N., Jul 16 2009, In : Japanese journal of clinical oncology. 39, 7, p. 425-430 6 p.

Research output: Contribution to journalArticle

Neutropenia
Lung Neoplasms
Pharmacokinetics
Drug Therapy
pegfilgrastim
13 Citations (Scopus)

A phase i escalating single-dose and weekly fixed-dose study of cetuximab pharmacokinetics in Japanese patients with solid tumors

Shirao, K., Yoshino, T., Boku, N., Kato, K., Hamaguchi, T., Yasui, H., Yamamoto, N., Tanigawara, Y., Nolting, A. & Yoshino, S., Jul 1 2009, In : Cancer chemotherapy and pharmacology. 64, 3, p. 557-564 8 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Tumors
Toxicity
Neoplasms
Epidermal Growth Factor Receptor

Appropriate hemodialysis scheduling based on therapeutic drug monitoring of carboplatin in a patient with lung cancer and chronic renal failure

Kamata, H., Asano, K., Soejima, K., Shirahata, T., Nakatani, M., Inamoto, H., Iketani, O., Yamayoshi, Y., Tanigawara, Y. & Ishizaka, A., Sep 2009, In : Japanese Journal of Cancer and Chemotherapy. 36, 9, p. 1529-1532 4 p.

Research output: Contribution to journalArticle

Drug Monitoring
Carboplatin
Chronic Kidney Failure
Renal Dialysis
Lung Neoplasms
16 Citations (Scopus)

Comparative pharmacodynamics of olmesartan and azelnidipine in patients with hypertension: A population pharmacokinetic/pharmacodynamic analysis

Tanigawara, Y., Yoshihara, K., Kuramoto, K. & Arakawa, K., Jan 1 2009, In : Drug Metabolism And Pharmacokinetics. 24, 4, p. 376-388 13 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Hypertension
Blood Pressure
Renin
Pharmaceutical Preparations
10 Citations (Scopus)

Effects of α-adrenoceptor antagonist doxazosin on MDR1-mediated multidrug resistance and transcellular transport

Takara, K., Sakaeda, T., Kakumoto, M., Tanigawara, Y., Kobayashi, H., Okumura, K., Ohnishi, N. & Yokoyama, T., Jan 1 2009, In : Oncology research. 17, 11-12, p. 527-533 7 p.

Research output: Contribution to journalArticle

Doxazosin
Transcytosis
Multiple Drug Resistance
Terazosin
Adrenergic Receptors
7 Citations (Scopus)

Impact of pharmacokinetics and pharmacogenetics on the efficacy of pranlukast in Japanese asthmatics

Asano, K., Nakade, S., Shiomi, T., Nakajima, T., Suzuki, Y., Fukunaga, K., Oguma, T., Sayama, K., Fujita, H., Tanigawara, Y. & Ishizaka, A., Aug 1 2009, In : Respirology. 14, 6, p. 822-827 6 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Pharmacokinetics
Therapeutic Uses
Asthma
Population
3 Citations (Scopus)

Population pharmacokinetics and pharmacodynamics of 500 mg oral dose levofloxacin in respiratory tract infection patients

Tanigawara, Y., Shimizu, T. & Totsuka, K., Jul 1 2009, In : Japanese Journal of Chemotherapy. 57, SUPPL. 2, p. 47-54 8 p.

Research output: Contribution to journalArticle

Levofloxacin
Respiratory Tract Infections
Pharmacokinetics
Population
Microbial Sensitivity Tests
2008
11 Citations (Scopus)

An open clinical study of arbekacin 200 mg q.d. in patients infected with methicillin-resistant Staphylococcus aureus (MRSA) - A clinical pharmacology study

Aikawa, N., Kohno, S., Kaku, M., Watanabe, A., Yamaguchi, K. & Tanigawara, Y., May 1 2008, In : Japanese Journal of Chemotherapy. 56, 3, p. 299-312 14 p.

Research output: Contribution to journalArticle

Clinical Pharmacology
Methicillin-Resistant Staphylococcus aureus
Drug-Related Side Effects and Adverse Reactions
Safety
Staphylococcal Pneumonia

Efficacy, safety and pharmacokinetics of micafungin in pediatric patients with deep mycoses

Sunakawa, K., Tsukimoto, I., Toyonaga, Y., Tsunematsu, Y., Iwai, N. & Tanigawara, Y., Mar 1 2008, In : Japanese Journal of Chemotherapy. 56, 2, p. 190-201 12 p.

Research output: Contribution to journalArticle

Mycoses
Pharmacokinetics
Pediatrics
Safety
Drug-Related Side Effects and Adverse Reactions
22 Citations (Scopus)

Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole

Mihara, A., Mori, T., Aisa, Y., Yamazaki, R., Iketani, O., Tanigawara, Y., Ikeda, Y. & Okamoto, S., Jan 1 2008, In : European Journal of Clinical Pharmacology. 64, 1, p. 89-91 3 p.

Research output: Contribution to journalArticle

Fluconazole
Drug Interactions
Tacrolimus
Cyclosporine
Calcineurin Inhibitors