Yusuke Tanigawara &ndash; Research Output

2019

Cerebrospinal pharmacokinetic and pharmacodynamic analysis of efficacy of meropenem in paediatric patients with bacterial meningitis

Ohata, Y., Tomita, Y., Sunakawa, K., Drusano, G. L. & Tanigawara, Y., Sep 1 2019, In : International Journal of Antimicrobial Agents. 54, 3, p. 292-300 9 p.

Research output: Contribution to journal › Article

meropenem

Bacterial Meningitides

Cerebrospinal Fluid

Pharmacokinetics

Pediatrics

Gefitinib exposure and occurrence of interstitial lung disease in Japanese patients with non-small-cell lung cancer

Kawata, T., Higashimori, M., Itoh, Y., Tomkinson, H., Johnson, M. G., Tang, W., Nyberg, F., Jiang, H. & Tanigawara, Y., May 1 2019, In : Cancer chemotherapy and pharmacology. 83, 5, p. 849-858 10 p.

Research output: Contribution to journal › Article

Pulmonary diseases

Interstitial Lung Diseases

Non-Small Cell Lung Carcinoma

Cells

Glycoproteins

1 Citation (Scopus)

Individualized Dosing of Axitinib Based on First-Dose Area Under the Concentration–Time Curve for Metastatic Renal-Cell Carcinoma

Miura, Y., Imamura, C. K., Uchino, K., Kishida, T., Matsubara, N., Shinojima, T., Kondo, K., Hongo, F., Yoshimura, K., Tanigawara, Y. & Takano, T., Feb 1 2019, In : Clinical Genitourinary Cancer. 17, 1, p. e1-e11

Research output: Contribution to journal › Article

Renal Cell Carcinoma

Area Under Curve

Disease-Free Survival

Survival Rate

Confidence Intervals

2018

Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype-Guided Dosing of Tamoxifen

Nakamura, T., Toshimoto, K., Lee, W., Imamura, C. K., Tanigawara, Y. & Sugiyama, Y., Jul 2018, In : CPT: Pharmacometrics and Systems Pharmacology. 7, 7, p. 474-482 9 p.

Research output: Contribution to journal › Article

Cytochrome P-450 CYP2D6

Pharmacokinetics

Tamoxifen

Genotype

Predict

16 Citations (Scopus)

Clinical Factors Predicting Detection of T790M Mutation in Rebiopsy for EGFR-Mutant Non–small-cell Lung Cancer

Kawamura, T., Kenmotsu, H., Omori, S., Nakashima, K., Wakuda, K., Ono, A., Naito, T., Murakami, H., Omae, K., Mori, K., Tanigawara, Y., Nakajima, T., Ohde, Y., Endo, M. & Takahashi, T., Mar 1 2018, In : Clinical Lung Cancer. 19, 2, p. e247-e252

Research output: Contribution to journal › Article

Epidermal Growth Factor Receptor

Non-Small Cell Lung Carcinoma

Protein-Tyrosine Kinases

Mutation

Recurrence

6 Citations (Scopus)

Modeling and simulation of bone mineral density in Japanese osteoporosis patients treated with zoledronic acid using tartrate-resistant acid phosphatase 5b, a bone resorption marker

Mori, Y., Kasai, H., Ose, A., Serada, M., Ishiguro, M., Shiraki, M. & Tanigawara, Y., May 1 2018, In : Osteoporosis International. 29, 5, p. 1155-1163 9 p.

Research output: Contribution to journal › Article

zoledronic acid

Bone Resorption

Bone Density

Osteoporosis

Theoretical Models

Pharmacodynamic analysis of eribulin safety in breast cancer patients using real-world postmarketing surveillance data

Kawamura, T., Kasai, H., Fermanelli, V., Takahashi, T., Sakata, Y., Matsuoka, T., Ishii, M. & Tanigawara, Y., Sep 2018, In : Cancer science. 109, 9, p. 2822-2829 8 p.

Research output: Contribution to journal › Article

eribulin

Neutrophils

Breast Neoplasms

Safety

Neutropenia

2017

5 Citations (Scopus)

Effect of everolimus on the glucose metabolic pathway in mouse skeletal muscle cells (C2C12)

Yoshida, K., Imamura, C. K., Hara, K., Mochizuki, M. & Tanigawara, Y., Aug 1 2017, In : Metabolomics. 13, 8, 98.

Research output: Contribution to journal › Article

Metabolic Networks and Pathways

Muscle Cells

Muscle

Skeletal Muscle

Cells

1 Citation (Scopus)

Population Pharmacokinetic and Exposure–Response Analysis of Weekly Teriparatide in Osteoporosis Patients

Ose, A., Serada, M., Yamashita, K., Tsurui, K. & Tanigawara, Y., Dec 1 2017, In : Journal of Clinical Pharmacology. 57, 12, p. 1545-1553 9 p.

Research output: Contribution to journal › Article

Teriparatide

Osteoporosis

Pharmacokinetics

Bone Density

Population

2 Citations (Scopus)

Population Pharmacokinetics of Diazoxide in Children with Hyperinsulinemic Hypoglycemia

Kizu, R., Nishimura, K., Sato, R., Kosaki, K., Tanaka, T., Tanigawara, Y. & Hasegawa, T., Nov 1 2017, In : Hormone Research in Paediatrics. 88, 5, p. 316-323 8 p.

Research output: Contribution to journal › Article

Diazoxide

Hypoglycemia

Pharmacokinetics

Population

Hyperglycemia

5 Citations (Scopus)

The effects of advanced age and serum α₁-acid glycoprotein on docetaxel unbound exposure and dose-limiting toxicity in cancer patients

Kenmotsu, H., Imamura, C. K., Ono, A., Omori, S., Nakashima, K., Wakuda, K., Taira, T., Naito, T., Murakami, H., Takahashi, T. & Tanigawara, Y., Nov 2017, In : British journal of clinical pharmacology. 83, 11, p. 2416-2425 10 p.

Research output: Contribution to journal › Article

docetaxel

Glycoproteins

Acids

Serum

Neoplasms

2016

3 Citations (Scopus)

Development of an S-1 dosage formula based on renal function by a prospective pharmacokinetic study

Booka, E., Imamura, C. K., Takeuchi, H., Hamamoto, Y., Gomi, D., Mizukami, T., Ichiyama, T., Tateishi, K., Takahashi, T., Kawakubo, H., Soejima, K., Boku, N., Tanigawara, Y. & Kitagawa, Y., Jul 1 2016, In : Gastric Cancer. 19, 3, p. 876-886 11 p.

Research output: Contribution to journal › Article

Fluorouracil

Pharmacokinetics

Prospective Studies

Kidney

Area Under Curve

16 Citations (Scopus)

Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole

Imamura, C. K., Furihata, K., Okamoto, S. & Tanigawara, Y., Apr 1 2016, In : Journal of Clinical Pharmacology. 56, 4, p. 408-413 6 p.

Research output: Contribution to journal › Article

Tacrolimus

Cytochrome P-450 Enzyme System

Pharmacokinetics

Genotype

Cytochrome P-450 CYP3A

2014

11 Citations (Scopus)

Clinical practice guidelines for therapeutic drug monitoring of arbekacin: A consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

Okada, K., Kimura, T., Mikamo, H., Kasahara, K., Seki, M., Takakura, S., Tokimatsu, I., Ohmagari, N., Takahashi, Y., Matsumoto, K., Igarashi, M., Kobayashi, M., Hamada, Y., Mochizuki, T., Kimura, M., Nishi, Y., Tanigawara, Y. & Takesue, Y., Jan 2014, In : Journal of Infection and Chemotherapy. 20, 1, p. 1-5 5 p.

Research output: Contribution to journal › Article

Drug Monitoring

Practice Guidelines

Drug Therapy

Japan

Serum

7 Citations (Scopus)

Forced expression of S100A10 reduces sensitivity to oxaliplatin in colorectal cancer cells

Suzuki, S. & Tanigawara, Y., May 9 2014, In : Proteome Science. 12, 1, 26.

Research output: Contribution to journal › Article

oxaliplatin

Fluorouracil

Colorectal Neoplasms

Cells

Annexin A2

6 Citations (Scopus)

Population PK modelling and simulation based on fluoxetine and norfluoxetine concentrations in milk: a milk concentration-based prediction model

Tanoshima, R., Bournissen, F. G. A., Tanigawara, Y., Kristensen, J. H., Taddio, A., Ilett, K. F., Begg, E. J., Wallach, I. & Ito, S., Oct 1 2014, In : British journal of clinical pharmacology. 78, 4, p. 918-928 11 p.

Research output: Contribution to journal › Article

Fluoxetine

Milk

Population

Pharmacokinetics

norfluoxetine

18 Citations (Scopus)

Sunitinib-induced severe toxicities in a japanese patient with the ABCG2 421 AA genotype

Miura, Y., Imamura, C. K., Fukunaga, K., Katsuyama, Y., Suyama, K., Okaneya, T., Mushiroda, T., Ando, Y., Takano, T. & Tanigawara, Y., Dec 16 2014, In : BMC cancer. 14, 1, 964.

Research output: Contribution to journal › Article

Genotype

sunitinib

Hand-Foot Syndrome

Vascular Endothelial Growth Factor Receptor

Pharmacogenetics

2013

4 Citations (Scopus)

Clinical and bacteriological efficacies of sitafloxacin against community-acquired pneumonia caused by Streptococcus pneumoniae: Nested cohort within a multicenter clinical trial

Fujita, J., Niki, Y., Kadota, J. I., Yanagihara, K., Kaku, M., Watanabe, A., Aoki, N., Hori, S., Tanigawara, Y., Cash, H. L. & Kohno, S., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 472-479 8 p.

Research output: Contribution to journal › Article

Streptococcus pneumoniae

Multicenter Studies

Pneumonia

Clinical Trials

Levofloxacin

12 Citations (Scopus)

Clinical dose findings of sitafloxacin treatment: Pharmacokinetic- pharmacodynamic analysis of two clinical trial results for community-acquired respiratory tract infections

Kohno, S., Niki, Y., Kadota, J. I., Yanagihara, K., Kaku, M., Watanabe, A., Aoki, N., Hori, S., Fujita, J. & Tanigawara, Y., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 486-494 9 p.

Research output: Contribution to journal › Article

Community-Acquired Infections

Respiratory Tract Infections

Pharmacokinetics

Clinical Trials

Microbial Sensitivity Tests

41 Citations (Scopus)

Pharmacogenetic determinants associated with sunitinib-induced toxicity and ethnic difference in Korean metastatic renal cell carcinoma patients

Kim, H. R., Park, H. S., Kwon, W. S., Lee, J. H., Tanigawara, Y., Lim, S. M., Kim, H. S., Shin, S. J., Ahn, J. B. & Rha, S. Y., Oct 1 2013, In : Cancer chemotherapy and pharmacology. 72, 4, p. 825-835 11 p.

Research output: Contribution to journal › Article

Hand-Foot Syndrome

Pharmacogenetics

Renal Cell Carcinoma

Toxicity

Neutropenia

12 Citations (Scopus)

Polymorphisms in the UGT1A1 gene predict adverse effects of irinotecan in the treatment of gynecologic cancer in Japanese patients

Hirasawa, A., Zama, T., Akahane, T., Nomura, H., Kataoka, F., Saito, K., Okubo, K., Tominaga, E., Makita, K., Susumu, N., Kosaki, K., Tanigawara, Y. & Aoki, D., Dec 1 2013, In : Journal of Human Genetics. 58, 12, p. 794-798 5 p.

Research output: Contribution to journal › Article

irinotecan

Glucuronosyltransferase

Uridine Diphosphate

Genes

Neoplasms

9 Citations (Scopus)

Population pharmacokinetics and pharmacodynamics of sitafloxacin in patients with community-acquired respiratory tract infections

Tanigawara, Y., Kaku, M., Totsuka, K., Tsuge, H. & Saito, A., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 5, p. 858-866 9 p.

Research output: Contribution to journal › Article

Community-Acquired Infections

Respiratory Tract Infections

Pharmacokinetics

Population

sitafloxacin

61 Citations (Scopus)

Practice guidelines for therapeutic drug monitoring of vancomycin: A consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

Matsumoto, K., Takesue, Y., Ohmagari, N., Mochizuki, T., Mikamo, H., Seki, M., Takakura, S., Tokimatsu, I., Takahashi, Y., Kasahara, K., Okada, K., Igarashi, M., Kobayashi, M., Hamada, Y., Kimura, M., Nishi, Y., Tanigawara, Y. & Kimura, T., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 365-380 16 p.

Research output: Contribution to journal › Article

Drug Monitoring

Vancomycin

Methicillin-Resistant Staphylococcus aureus

Practice Guidelines

Guidelines

54 Citations (Scopus)

Practice guidelines for therapeutic drug monitoring of voriconazole: A consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

Hamada, Y., Tokimatsu, I., Mikamo, H., Kimura, M., Seki, M., Takakura, S., Ohmagari, N., Takahashi, Y., Kasahara, K., Matsumoto, K., Okada, K., Igarashi, M., Kobayashi, M., Mochizuki, T., Nishi, Y., Tanigawara, Y., Kimura, T. & Takesue, Y., Jan 1 2013, In : Journal of Infection and Chemotherapy. 19, 3, p. 381-392 12 p.

Research output: Contribution to journal › Article

Drug Monitoring

Practice Guidelines

Guidelines

Drug Therapy

Voriconazole

2012

41 Citations (Scopus)

A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese

Kiyotani, K., Mushiroda, T., Tsunoda, T., Morizono, T., Hosono, N., Kubo, M., Tanigawara, Y., Imamura, C. K., Flockhart, D. A., Aki, F., Hirata, K., Takatsuka, Y., Okazaki, M., Ohsumi, S., Yamakawa, T., Sasa, M., Nakamura, Y. & Zembutsu, H., Apr 1 2012, In : Human molecular genetics. 21, 7, p. 1665-1672 8 p., ddr597.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Tamoxifen

Breast Neoplasms

Survival

Recurrence

2 Citations (Scopus)

Blood-direct InvaderPlus® as a new method for genetic testing

Hirasawa, A., Akahane, T., Tanigawara, Y. & Aoki, D., Aug 1 2012, In : Personalized Medicine. 9, 6, p. 657-663 7 p.

Research output: Contribution to journal › Article

Genetic Testing

Genetic Polymorphisms

Genes

64 Citations (Scopus)

Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients

Kiyotani, K., Mushiroda, T., Imamura, C. K., Tanigawara, Y., Hosono, N., Kubo, M., Sasa, M., Nakamura, Y. & Zembutsu, H., Jan 1 2012, In : Breast Cancer Research and Treatment. 131, 1, p. 137-145 9 p.

Research output: Contribution to journal › Article

Cytochrome P-450 CYP2D6

Tamoxifen

Genotype

Breast Neoplasms

Alleles

17 Citations (Scopus)

Expression changes in arrestin β 1 and genetic variation in catechol-O-methyltransferase are biomarkers for the response to morphine treatment in cancer patients

Matsuoka, H., Arao, T., Makimura, C., Takeda, M., Kiyota, H., Tsurutani, J., Fujita, Y., Matsumoto, K., Kimura, H., Otsuka, M., Koyama, A., Imamura, C. K., Tanigawara, Y., Yamanaka, T., Tanaka, K., Nishio, K. & Nakagawa, K., May 1 2012, In : Oncology reports. 27, 5, p. 1393-1399 7 p.

Research output: Contribution to journal › Article

Arrestin

Catechol O-Methyltransferase

Morphine

Biomarkers

Neoplasms

17 Citations (Scopus)

Optimal dose finding of garenoxacin based on population pharmacokinetics/pharmacodynamics and Monte Carlo simulation

Tanigawara, Y., Nozawa, K. & Tsuda, H., Jan 1 2012, In : European Journal of Clinical Pharmacology. 68, 1, p. 39-53 15 p.

Research output: Contribution to journal › Article

Pharmacokinetics

Population

Quinolones

Microbial Sensitivity Tests

Respiratory System

8 Citations (Scopus)

Pharmacokinetics of mizoribine in adult living donor liver transplantation

Shinoda, M., Tanabe, M., Kawachi, S., Ono, Y., Hayakawa, T., Iketani, O., Kojima, M., Itano, O., Obara, H., Kitago, M., Hibi, T., Matsubara, K., Shimojima, N., Fuchimoto, Y., Hoshino, K., Wakabayashi, G., Shimazu, M., Tanigawara, Y., Kuroda, T., Morikawa, Y. & 2 others, Kitajima, M. & Kitagawa, Y., Jun 1 2012, In : Transplantation Proceedings. 44, 5, p. 1329-1335 7 p.

Research output: Contribution to journal › Article

Living Donors

Liver Transplantation

Pharmacokinetics

Serum

Glomerular Filtration Rate

2011

110 Citations (Scopus)

A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures - A randomized, active comparator, double-blind study

Matsumoto, T., Ito, M., Hayashi, Y., Hirota, T., Tanigawara, Y., Sone, T., Fukunaga, M., Shiraki, M. & Nakamura, T., Oct 1 2011, In : Bone. 49, 4, p. 605-612 8 p.

Research output: Contribution to journal › Article

Osteoporotic Fractures

Cholecalciferol

Double-Blind Method

Bone Density

Wrist

142 Citations (Scopus)

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

Watanabe, M., Horai, Y., Houten, S. M., Morimoto, K., Sugizaki, T., Arita, E., Mataki, C., Sato, H., Tanigawara, Y., Schoonjans, K., Itoh, H. & Auwerx, J., Jul 29 2011, In : Journal of Biological Chemistry. 286, 30, p. 26913-26920 8 p.

Research output: Contribution to journal › Article

Medical problems

Bile Acids and Salts

Energy Metabolism

Obesity

High Fat Diet

23 Citations (Scopus)

Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in patients with disseminated intravascular coagulation and normal subjects

Tsuruta, K., Yamada, Y., Serada, M. & Tanigawara, Y., Sep 1 2011, In : Journal of Clinical Pharmacology. 51, 9, p. 1276-1285 10 p.

Research output: Contribution to journal › Article

Thrombomodulin

Disseminated Intravascular Coagulation

Pharmacokinetics

Population

Hematocrit

13 Citations (Scopus)

Optimal dosage regimen of meropenem for pediatric patients based on pharmacokinetic/pharmacodynamic considerations

Ohata, Y., Tomita, Y., Nakayama, M., Kozuki, T., Sunakawa, K. & Tanigawara, Y., Jan 1 2011, In : Drug Metabolism And Pharmacokinetics. 26, 5, p. 523-531 9 p.

Research output: Contribution to journal › Article

meropenem

Pharmacokinetics

Pediatrics

Bacteria

Japan

9 Citations (Scopus)

Optimal treatment schedule of meropenem for adult patients with febrile neutropenia based on pharmacokinetic-pharmacodynamic analysis

Ohata, Y., Tomita, Y., Nakayama, M., Tamura, K. & Tanigawara, Y., Jan 1 2011, In : Journal of Infection and Chemotherapy. 17, 6, p. 831-841 11 p.

Research output: Contribution to journal › Article

meropenem

Febrile Neutropenia

Appointments and Schedules

Pharmacokinetics

Therapeutics

6 Citations (Scopus)

Pharmacokinetics of eldecalcitol in primary osteoporosis patients - Randomized, double-blind, multicentre, long-term phase III clinical study

Miyata, K., Abe, M., Terao, K., Kawanishi, T., Tsuji, N., Shiraki, M., Nakamura, T., Matsumoto, T. & Tanigawara, Y., Mar 2011, In : Japanese Pharmacology and Therapeutics. 39, 3, p. 299-307 9 p.

Research output: Contribution to journal › Article

Osteoporosis

Pharmacokinetics

Serum

eldecalcitol

Clinical Studies

Population pharmacokinetics and pharmacodynamics of levofloxacin following intravenous infusion for respiratory tract infection

Tanigawara, Y., Shimizu, T. & Totsuka, K., May 1 2011, In : Japanese Journal of Chemotherapy. 59, SUPPL. 1, p. 55-64 10 p.

Research output: Contribution to journal › Article

Levofloxacin

Intravenous Infusions

Respiratory Tract Infections

Pharmacokinetics

Population

6 Citations (Scopus)

S100A10 protein expression is associated with oxaliplatin sensitivity in human colorectal cancer cells

Suzuki, S., Yamayoshi, Y., Nishimuta, A. & Tanigawara, Y., Dec 30 2011, In : Proteome Science. 9, 76.

Research output: Contribution to journal › Article

oxaliplatin

S100 Proteins

antineoplaston A10

Colorectal Neoplasms

Cells

2010

17 Citations (Scopus)

Pharmacokinetics of S-1 and CYP2A6 genotype in Japanese patients with advanced cancer

Hirose, T., Fujita, K. I., Nishimura, K., Ishida, H., Yamashita, K., Sunakawa, Y., Mizuno, K., Miwa, K., Nagashima, F., Tanigawara, Y., Adachi, M. & Sasaki, Y., Jan 1 2010, In : Oncology Reports. 24, 2, p. 529-536 8 p.

Research output: Contribution to journal › Article

Pharmacokinetics

Genotype

Area Under Curve

Fluorouracil

Tegafur

170 Citations (Scopus)

Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients

Kiyotani, K., Mushiroda, T., Imamura, C. K., Hosono, N., Tsunoda, T., Kubo, M., Tanigawara, Y., Flockhart, D. A., Desta, Z., Skaar, T. C., Aki, F., Hirata, K., Takatsuka, Y., Okazaki, M., Ohsumi, S., Yamakawa, T., Sasa, M., Nakamura, Y. & Zembutsu, H., Mar 10 2010, In : Journal of Clinical Oncology. 28, 8, p. 1287-1293 7 p.

Research output: Contribution to journal › Article

Cytochrome P-450 CYP2D6

Tamoxifen

Breast Neoplasms

Alleles

Therapeutics

2009

14 Citations (Scopus)

A pharmacokinetic and dose escalation study of pegfilgrastim (KRN125) in lung cancer patients with chemotherapy-induced neutropenia

Yamamoto, N., Sekine, I., Nakagawa, K., Takada, M., Fukuoka, M., Tanigawara, Y. & Saijo, N., Jul 16 2009, In : Japanese journal of clinical oncology. 39, 7, p. 425-430 6 p.

Research output: Contribution to journal › Article

Neutropenia

Lung Neoplasms

Pharmacokinetics

Drug Therapy

pegfilgrastim

13 Citations (Scopus)

A phase i escalating single-dose and weekly fixed-dose study of cetuximab pharmacokinetics in Japanese patients with solid tumors

Shirao, K., Yoshino, T., Boku, N., Kato, K., Hamaguchi, T., Yasui, H., Yamamoto, N., Tanigawara, Y., Nolting, A. & Yoshino, S., Jul 1 2009, In : Cancer chemotherapy and pharmacology. 64, 3, p. 557-564 8 p.

Research output: Contribution to journal › Article

Pharmacokinetics

Tumors

Toxicity

Neoplasms

Epidermal Growth Factor Receptor

Appropriate hemodialysis scheduling based on therapeutic drug monitoring of carboplatin in a patient with lung cancer and chronic renal failure

Kamata, H., Asano, K., Soejima, K., Shirahata, T., Nakatani, M., Inamoto, H., Iketani, O., Yamayoshi, Y., Tanigawara, Y. & Ishizaka, A., Sep 2009, In : Japanese Journal of Cancer and Chemotherapy. 36, 9, p. 1529-1532 4 p.

Research output: Contribution to journal › Article

Drug Monitoring

Carboplatin

Chronic Kidney Failure

Renal Dialysis

Lung Neoplasms

16 Citations (Scopus)

Comparative pharmacodynamics of olmesartan and azelnidipine in patients with hypertension: A population pharmacokinetic/pharmacodynamic analysis

Tanigawara, Y., Yoshihara, K., Kuramoto, K. & Arakawa, K., Jan 1 2009, In : Drug Metabolism And Pharmacokinetics. 24, 4, p. 376-388 13 p.

Research output: Contribution to journal › Article

Pharmacokinetics

Hypertension

Blood Pressure

Renin

Pharmaceutical Preparations

10 Citations (Scopus)

Effects of α-adrenoceptor antagonist doxazosin on MDR1-mediated multidrug resistance and transcellular transport

Takara, K., Sakaeda, T., Kakumoto, M., Tanigawara, Y., Kobayashi, H., Okumura, K., Ohnishi, N. & Yokoyama, T., Jan 1 2009, In : Oncology research. 17, 11-12, p. 527-533 7 p.

Research output: Contribution to journal › Article

Doxazosin

Transcytosis

Multiple Drug Resistance

Terazosin

Adrenergic Receptors

7 Citations (Scopus)

Impact of pharmacokinetics and pharmacogenetics on the efficacy of pranlukast in Japanese asthmatics

Asano, K., Nakade, S., Shiomi, T., Nakajima, T., Suzuki, Y., Fukunaga, K., Oguma, T., Sayama, K., Fujita, H., Tanigawara, Y. & Ishizaka, A., Aug 1 2009, In : Respirology. 14, 6, p. 822-827 6 p.

Research output: Contribution to journal › Article

Pharmacogenetics

Pharmacokinetics

Therapeutic Uses

Asthma

Population

3 Citations (Scopus)

Population pharmacokinetics and pharmacodynamics of 500 mg oral dose levofloxacin in respiratory tract infection patients

Tanigawara, Y., Shimizu, T. & Totsuka, K., Jul 1 2009, In : Japanese Journal of Chemotherapy. 57, SUPPL. 2, p. 47-54 8 p.

Research output: Contribution to journal › Article

Levofloxacin

Respiratory Tract Infections

Pharmacokinetics

Population

Microbial Sensitivity Tests

2008

11 Citations (Scopus)

An open clinical study of arbekacin 200 mg q.d. in patients infected with methicillin-resistant Staphylococcus aureus (MRSA) - A clinical pharmacology study

Aikawa, N., Kohno, S., Kaku, M., Watanabe, A., Yamaguchi, K. & Tanigawara, Y., May 1 2008, In : Japanese Journal of Chemotherapy. 56, 3, p. 299-312 14 p.

Research output: Contribution to journal › Article

Clinical Pharmacology

Methicillin-Resistant Staphylococcus aureus

Drug-Related Side Effects and Adverse Reactions

Safety

Staphylococcal Pneumonia

Efficacy, safety and pharmacokinetics of micafungin in pediatric patients with deep mycoses

Sunakawa, K., Tsukimoto, I., Toyonaga, Y., Tsunematsu, Y., Iwai, N. & Tanigawara, Y., Mar 1 2008, In : Japanese Journal of Chemotherapy. 56, 2, p. 190-201 12 p.

Research output: Contribution to journal › Article

Mycoses

Pharmacokinetics

Pediatrics

Safety

Drug-Related Side Effects and Adverse Reactions

22 Citations (Scopus)

Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole

Mihara, A., Mori, T., Aisa, Y., Yamazaki, R., Iketani, O., Tanigawara, Y., Ikeda, Y. & Okamoto, S., Jan 1 2008, In : European Journal of Clinical Pharmacology. 64, 1, p. 89-91 3 p.

Research output: Contribution to journal › Article

Fluconazole

Drug Interactions

Tacrolimus

Cyclosporine

Calcineurin Inhibitors