2019 NCCN Consensus Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL)

Mark Warren Clemens, Eric D. Jacobsen, Steven M. Horwitz

Research output: Contribution to journalArticle

Abstract

National Comprehensive Cancer Network (NCCN) guidelines represent the consensus standard of care for diagnosis and management of the majority of known cancers. NCCN guidelines on breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) have been recognized by the US Food and Drug Administration and widely advocated by national specialty societies. Consensus guidelines have helped create a treatment standardization for BIA-ALCL at all stages of disease. NCCN guidelines are evidence-based where possible and utilize expert consensus opinion to fill in gaps that may exist. NCCN undergoes annual panel review by multidisciplinary faculty members, and this article represents the most up-to-date 2019 guidelines. Recommendations focus on parameters for achieving reliable diagnosis and disease management and emphasize the critical role for complete surgical ablation. Suggestions for adjunct treatments and chemotherapy regimens are included for advanced BIA-ALCL with lymph node involvement. BIA-ALCL recurrence and management of unresectable disease, and organ metastasis are addressed. Adherence to recognized BIA-ALCL guidelines ensures patients receive the most current efficacious treatment available.

Original languageEnglish (US)
Pages (from-to)S3-S13
JournalAesthetic surgery journal
Volume39
DOIs
StatePublished - Jan 31 2019

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Anaplastic Large-Cell Lymphoma
Breast Implants
Guidelines
Neoplasms
Disease Management
Therapeutics
Expert Testimony
United States Food and Drug Administration
Standard of Care
Lymph Nodes
Neoplasm Metastasis
Recurrence
Drug Therapy

ASJC Scopus subject areas

  • Surgery

Cite this

2019 NCCN Consensus Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL). / Clemens, Mark Warren; Jacobsen, Eric D.; Horwitz, Steven M.

In: Aesthetic surgery journal, Vol. 39, 31.01.2019, p. S3-S13.

Research output: Contribution to journalArticle

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