Find Research Outputs

2018
3 Citations

A Bayesian basket trial design using a calibrated Bayesian hierarchical model

Chu, Y. & Yuan, Y., Apr 1 2018, In : Clinical Trials. 15, 2, p. 149-158 10 p.

Research output: Contribution to journalArticle

Therapeutics
Neoplasms
Molecular Biology
Software
Research
Bayesian Learning
Machine Learning
Decision Rules
Q-learning
Regression Model
1 Citations

A Bayesian multi-stage cost-effectiveness design for animal studies in stroke research

Cai, C., Ning, J. & Huang, X., Apr 1 2018, In : Statistical Methods in Medical Research. 27, 4, p. 1219-1229 11 p.

Research output: Contribution to journalArticle

Cost-effectiveness
Stroke
Cost-Benefit Analysis
Animals
Adaptive Design
1 Citations

A Bayesian Phase I/II Trial Design for Immunotherapy

Liu, S., Guo, B. & Yuan, Y., Jul 3 2018, In : Journal of the American Statistical Association. 113, 523, p. 1016-1027 12 p.

Research output: Contribution to journalArticle

Immunotherapy
Dose
Immune Response
Toxicity
Efficacy

A Bayesian screening approach for hepatocellular carcinoma using multiple longitudinal biomarkers

Tayob, N., Stingo, F., Do, K-A., Lok, A. S. F. & Feng, Z., Mar 1 2018, In : Biometrics. 74, 1, p. 249-259 11 p.

Research output: Contribution to journalArticle

Bayes Theorem
Change Point
Biomarkers
hepatoma
Screening

A Bayesian semiparametric latent variable approach to causal mediation

Kim, C., Daniels, M., Li, Y., Milbury, K. & Cohen, L., Mar 30 2018, In : Statistics in Medicine. 37, 7, p. 1149-1161 13 p.

Research output: Contribution to journalArticle

Mediation
Latent Variables
Bayes Theorem
Renal Cell Carcinoma
Cluster Analysis
6 Citations

A Bayesian Simulation Model for Breast Cancer Screening, Incidence, Treatment, and Mortality

Huang, X., Li, Y., Song, J. & Berry, D., Apr 1 2018, In : Medical Decision Making. 38, 1_suppl, p. 78S-88S

Research output: Contribution to journalArticle

Early Detection of Cancer
Breast Neoplasms
Mortality
Incidence
Mammography

Abbreviated MRI Protocols in Breast Cancer Diagnostics

Deike-Hofmann, K., Koenig, F., Paech, D., Dreher, C., Delorme, S., Schlemmer, H-P. & Bickelhaupt, S., Jan 1 2018, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

Breast
Breast Neoplasms
Magnets
Early Detection of Cancer
Costs and Cost Analysis

Abdominal Wall Reconstruction

Selber, J. C., Aug 1 2018, In : Seminars in Plastic Surgery. 32, 3, 1 p.

Research output: Contribution to journalEditorial

Abdominal Wall

Abdominal Wall Reconstruction: An Integrated Approach

Boukovalas, S., Sisk, G. & Selber, J. C., Aug 1 2018, In : Seminars in Plastic Surgery. 32, 3, p. 107-119 13 p.

Research output: Contribution to journalArticle

Abdominal Wall
Surgeons

Abemaciclib for the treatment of breast cancer

Kotake, T. & Toi, M., Mar 24 2018, In : Expert Opinion on Pharmacotherapy. 19, 5, p. 517-524 8 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Clinical Trials
Therapeutics
Neoplasm Metastasis
Survival
1 Citations

A benchmark for comparing precision medicine methods in thyroid cancer diagnosis using tissue microarrays

Wang, C. W., Lee, Y. C., Calista, E., Zhou, F., Zhu, H., Suzuki, R., Komura, D., Ishikawa, S. & Cheng, S. P., May 15 2018, In : Bioinformatics. 34, 10, p. 1767-1773 7 p.

Research output: Contribution to journalArticle

Benchmarking
Precision Medicine
Microarrays
Thyroid Neoplasms
Microarray
3 Citations

Aberrant FGFR tyrosine kinase signaling enhances the warburg effect by reprogramming LDH Isoform expression and activity in prostate cancer

Liu, J., Chen, G., Liu, Z., Liu, S., Cai, Z., You, P., Ke, Y., Lai, L., Huang, Y., Gao, H., Zhao, L., Pelicano, H., Huang, P., McKeehan, W. L., Wu, C. L., Wang, C., Zhong, W. & Wang, F., Aug 15 2018, In : Cancer Research. 78, 16, p. 4459-4470 12 p.

Research output: Contribution to journalArticle

L-Lactate Dehydrogenase
Protein-Tyrosine Kinases
Receptor, Fibroblast Growth Factor, Type 1
Prostatic Neoplasms
Protein Isoforms
2 Citations

Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation

Cao, Y. M., Gu, J., Zhang, Y. S., Wei, W. J., Qu, N., Wen, D., Liao, T., Shi, R. L., Zhang, L., Ji, Q., Wang, Y., Sun, G. H., Zhao, Y. X., Wang, Y. J., Yu, J. & Zhu, Y. X., Jan 1 2018, In : Oncology reports. 39, 1, p. 338-348 11 p.

Research output: Contribution to journalArticle

Mutation
Genes
Methylation
Papillary Thyroid cancer
Cell Line

Aberrant methylation of EYA4 promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma

Luo, M., Li, Y., Shi, X., Yang, W., Zhou, F., Sun, N. & He, J., Jun 1 2018, In : Cancer Science. 109, 6, p. 1811-1824 14 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Methylation
trichostatin A
Glycogen Synthase Kinases
Cell Line

A biobank of patient-derived pediatric brain tumor models

Brabetz, S., Leary, S. E. S., Gröbner, S. N., Nakamoto, M. W., Şeker-Cin, H., Girard, E. J., Cole, B., Strand, A. D., Bloom, K. L., Hovestadt, V., Mack, N. L., Pakiam, F., Schwalm, B., Korshunov, A., Balasubramanian, G. P., Northcott, P. A., Pedro, K. D., Dey, J., Hansen, S., Ditzler, S. & 7 othersLichter, P., Chavez, L., Jones, D. T. W., Koster, J., Pfister, S. M., Kool, M. & Olson, J. M., Nov 1 2018, In : Nature medicine. 24, 11, p. 1752-1761 10 p.

Research output: Contribution to journalArticle

Pediatrics
Brain Neoplasms
Tumors
Brain
Heterografts
3 Citations

Ablation of colorectal liver metastasis: Interaction of ablation margins and RAS mutation profiling on local tumour progression-free survival

Calandri, M., Yamashita, S., Gazzera, C., Fonio, P., Veltri, A., Bustreo, S., Sheth, R. A., Yevich, S. M., Vauthey, J. N. & Odisio, B. C., Jul 1 2018, In : European Radiology. 28, 7, p. 2727-2734 8 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Neoplasm Metastasis
Mutation
Liver
Neoplasms

Ablative Hypofractionated Radiation Therapy Enhances Non-Small Cell Lung Cancer Cell Killing via Preferential Stimulation of Necroptosis In Vitro and In Vivo

Wang, H. H., Wu, Z. Q., Qian, D., Zaorsky, N. G., Qiu, M. H., Cheng, J. J., Jiang, C., Wang, J., Zeng, X. L., Liu, C. L., Tian, L. J., Ying, G. G., Meng, M. B., Hao, X. S. & Yuan, Z. Y., May 1 2018, In : International Journal of Radiation Oncology Biology Physics. 101, 1, p. 49-62 14 p.

Research output: Contribution to journalArticle

stimulation
Non-Small Cell Lung Carcinoma
lungs
radiation therapy
Radiotherapy
2 Citations

Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling

Meng, Q., Shi, S., Liang, C., Liang, D., Hua, J., Zhang, B., Xu, J. & Yu, X., Jul 6 2018, (Accepted/In press) In : Oncogene. p. 1-15 15 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinases
Epithelial-Mesenchymal Transition
gemcitabine
Snails
Pancreatic Neoplasms

Absence of TERT promoter mutations in colorectal precursor lesions and cancer

Cruvinel-Carloni, A., Yamane, L., Scapulatempo, C. N., Guimarães, D. & Reis, R. M. V., Jan 1 2018, In : Genetics and Molecular Biology. 41, 1, p. 82-84 3 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
Colorectal Neoplasms
Skin Neoplasms
Liver Neoplasms

Absence of Tumor on Repeat Transurethral Resection of Bladder Tumor Does Not Predict Final Pathologic T0 Stage in Bladder Cancer Treated with Radical Cystectomy

Kukreja, J. B., Porten, S., Golla, V., Ho, P. L., Noguera-Gonzalez, G., Navai, N., Kamat, A., Dinney, C. P. & Shah, J. B., Sep 1 2018, In : European Urology Focus. 4, 5, p. 720-724 5 p.

Research output: Contribution to journalArticle

Cystectomy
Urinary Bladder Neoplasms
Neoplasms
Survival
Urinary Bladder
7 Citations

Absolute number of new lesions on 18F-FDG PET/CT is more predictive of clinical response than SUV changes in metastatic melanoma patients receiving ipilimumab

Anwar, H., Sachpekidis, C., Winkler, J., Kopp-Schneider, A., Haberkorn, U., Hassel, J. C. & Dimitrakopoulou-Strauss, A., Mar 1 2018, In : European Journal of Nuclear Medicine and Molecular Imaging. 45, 3, p. 376-383 8 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Melanoma
Immunotherapy
Therapeutics
ipilimumab

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts

Yuan, A. L., Ricks, C. B., Bohm, A. K., Lun, X., Maxwell, L., Safdar, S., Bukhari, S., Gerber, A., Sayeed, W., Bering, E. A., Pedersen, H., Chan, J. A., Shen, Y., Marra, M., Kaplan, D. R., Mason, W., Goodman, L. D., Ezhilarasan, R., Kaufmann, A. B., Cabral, M. & 6 othersRobbins, S. M., Senger, D. L., Cahill, D. P., Sulman, E. P., Gregory Cairncross, J. & Blough, M. D., Aug 1 2018, In : PloS one. 13, 8, e0202860.

Research output: Contribution to journalArticle

temozolomide
Heterografts
Glioma
methyltransferases
DNA

Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial

Wang, L., Rule, S., Zinzani, P. L., Goy, A., Casasnovas, O., Smith, S. D., Damaj, G., Doorduijn, J., Lamy, T., Morschhauser, F., Panizo, C., Shah, B., Davies, A., Eek, R., Dupuis, J., Jacobsen, E., Kater, A. P., Le Gouill, S., Oberic, L., Robak, T. & 9 othersCovey, T., Dua, R., Hamdy, A., Huang, X., Izumi, R., Patel, P., Rothbaum, W., Slatter, J. G. & Jurczak, W., Feb 17 2018, In : The Lancet. 391, 10121, p. 659-667 9 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Therapeutics
Safety
acalabrutinib
Myalgia

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

Jerby-Arnon, L., Shah, P., Cuoco, M. S., Rodman, C., Su, M. J., Melms, J. C., Leeson, R., Kanodia, A., Mei, S., Lin, J. R., Wang, S., Rabasha, B., Liu, D., Zhang, G., Margolais, C., Ashenberg, O., Ott, P. A., Buchbinder, E. I., Haq, R., Hodi, F. S. & 32 othersBoland, G. M., Sullivan, R. J., Frederick, D. T., Miao, B., Moll, T., Flaherty, K. T., Herlyn, M., Jenkins, R. W., Thummalapalli, R., Kowalczyk, M. S., Cañadas, I., Schilling, B., Cartwright, A. N. R., Luoma, A. M., Malu, S., Hwu, P., Bernatchez, C., Forget, M. A., Barbie, D. A., Shalek, A. K., Tirosh, I., Sorger, P. K., Wucherpfennig, K., Van Allen, E. M., Schadendorf, D., Johnson, B. E., Rotem, A., Rozenblatt-Rosen, O., Garraway, L. A., Yoon, C. H., Izar, B. & Regev, A., Nov 1 2018, In : Cell. 175, 4, p. 984-997.e24

Research output: Contribution to journalArticle

T-cells
Tumors
Melanoma
Immunotherapy
Cells
Isogeneic Transplantation
Autologous Transplantation
Multiple Myeloma
Case-Control Studies

A Case of Primary Pulmonary Combined Small Cell Carcinoma With Adenocarcinoma Harboring the Same KLC1-ALK Fusion in Both Histologic Components

Bai, Q., Li, Y., Zhang, X., Zhu, X. & Zhou, X., Oct 1 2018, In : Journal of Thoracic Oncology. 13, 10, p. e197-e199

Research output: Contribution to journalLetter

Small Cell Carcinoma
Adenocarcinoma
Lung
1 Citations

A case of radiation-induced bullous morphea/lichen sclerosus overlap in a breast cancer patient

Petersen, E., Yazdani, L. & Hymes, S. R., Jan 1 2018, In : Reports of Practical Oncology and Radiotherapy. 23, 1, p. 47-49 3 p.

Research output: Contribution to journalArticle

Lichen Sclerosus et Atrophicus
Localized Scleroderma
Radiation
Breast Neoplasms
Radiodermatitis
1 Citations

A case report of advanced lung adenocarcinoma harboring KRAS mutation treated with anlotinib

Su, Y., Meng, Z., Xu, X., Wang, X., Zuo, R., Hou, Y., Li, K. & Chen, P., Jan 1 2018, In : Chinese Journal of Lung Cancer. 21, 5, p. 428-430 3 p.

Research output: Contribution to journalArticle

Mutation
Non-Small Cell Lung Carcinoma
Therapeutics
Platelet-Derived Growth Factor Receptors
Fibroblast Growth Factor Receptors

A Case Report—Stevens-Johnson Syndrome as an Adverse Effect of Capecitabine

Jadhav, P., Rogers, J. E. & Shroff, R., Sep 1 2018, In : Journal of Gastrointestinal Cancer. 49, 3, p. 349-350 2 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
Capecitabine
1 Citations

A catalyst for 50 years of cancer research

Wood, R., May 31 2018, In : Nature. 557, 7707, p. 648-649 2 p.

Research output: Contribution to journalShort survey

cancer
catalyst

Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in chronic pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Forsmark, C. E., Andersen, D. K., Farrar, J. T., Golden, M., Habtezion, A., Husain, S. Z., Li, L., Mayerle, J., Pandol, S. J., Uc, A., Zhu, Z. & Yadav, D., Nov 1 2018, In : Pancreas. 47, 10, p. 1200-1207 8 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Chronic Pancreatitis
Education
Pharmaceutical Preparations
Chronic Pain
Colorectal Neoplasms
Technology
Precision Medicine
DNA
Residual Neoplasm

Acceptance: A Letter to My Grieving Self

Hagan, K., Nov 1 2018, In : Anesthesiology. 129, 5, p. 1046-1047 2 p.

Research output: Contribution to journalArticle

Accounting for, Mitigating, and Choice of Margins for Moving Tumors

Li, H. & Chang, J. Y., Jun 1 2018, In : Seminars in radiation oncology. 28, 3, p. 194-200 7 p.

Research output: Contribution to journalReview article

Neoplasms
Radiotherapy
Standard of Care
Uncertainty
Therapeutics
2 Citations

Accuracy, safety, and reliability of novel phase I designs-response

Zhou, H., Yuan, Y. & Nie, L., Nov 1 2018, In : Clinical Cancer Research. 24, 21, p. 5483-5484 2 p.

Research output: Contribution to journalLetter

Safety

Accuracy of diagnosing mantle cell lymphoma and identifying its variants on fine-needle aspiration biopsy

Foshat, M., Stewart, J., Khoury, J., Staerkel, G. A. & Caraway, N. P., Jan 1 2018, (Accepted/In press) In : Cancer Cytopathology.

Research output: Contribution to journalArticle

Large-Core Needle Biopsy
Mantle-Cell Lymphoma
Fine Needle Biopsy
Flow Cytometry
Sensitivity and Specificity

Accuracy of High-Frequency Endoluminal Ultrasonography for Clinical Staging of Upper Tract Urothelial Carcinoma

Farnum, J. A., Vikram, R., Uppore Kukkillaya, A. R., Bedi, D. G., Dinney, C. P. & Matin, S., Sep 1 2018, In : Journal of Endourology. 32, 9, p. 806-811 6 p.

Research output: Contribution to journalArticle

Ultrasonography
Carcinoma
Pathology
Ureteroscopy
Muscles
1 Citations

Accuracy of Intraoperative Frozen Section Diagnosis of Borderline Ovarian Tumors by Hospital Type

Shah, J. S., Mackelvie, M., Gershenson, D. M., Ramalingam, P., Kott, M. M., Brown, J., Gauthier, P., Nugent, E., Ramondetta, L. M. & Frumovitz, M., Jan 1 2018, (Accepted/In press) In : Journal of Minimally Invasive Gynecology.

Research output: Contribution to journalArticle

Frozen Sections
Neoplasms
Carcinoma
Community Hospital
Odds Ratio
3 Citations

Accuracy of presurgical functional MR imaging for language mapping of brain tumors: A systematic review and meta-analysis

Weng, H. H., Noll, K. R., Johnson, J. M., Prabhu, S. S., Tsai, Y. H., Chang, S. W., Huang, Y. C., Lee, J. D., Yang, J. T., Yang, C. T., Tsai, Y. H., Yang, C. Y., Hazle, J. D., Schomer, D. F. & Liu, H-L. A., Feb 1 2018, In : Radiology. 286, 2, p. 512-523 12 p.

Research output: Contribution to journalReview article

Brain Neoplasms
Meta-Analysis
Language
Magnetic Resonance Imaging
Confidence Intervals

Accurate and Reproducible Diagnosis of Canine Soft Tissue Sarcoma Using Mass Spectrometry: A Step in the Right Direction

Keung, E. Z. & Roland, C. L., Nov 12 2018, In : Cancer Cell. 34, 5, p. 697-699 3 p.

Research output: Contribution to journalShort survey

Sarcoma
Canidae
Mass Spectrometry
Lasers
Technology

Accurate quantification of PGE2 in the polyposis in rat colon (Pirc) model by surrogate analyte-based UPLC–MS/MS

Yun, C., Dashwood, W. M., Kwong, L., Gao, S., Yin, T., Ling, Q., Singh, R., Dashwood, R. H. & Hu, M., Jan 30 2018, In : Journal of Pharmaceutical and Biomedical Analysis. 148, p. 42-50 9 p.

Research output: Contribution to journalArticle

Dinoprostone
Rats
Colon
Mucous Membrane
Biomarkers
1 Citations

Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer

Wang, J. N., Zhang, Z. R., Che, Y., Yuan, Z. Y., Lu, Z. L., Li, Y., Li, N., Wan, J., Sun, H. D., Sun, N., Puno, P. T. & He, J., Jul 3 2018, In : Cancer Biology and Therapy. 19, 7, p. 609-621 13 p.

Research output: Contribution to journalArticle

Kaurane Diterpenes
Cyclin B
Caspase 9
Diterpenes
G2 Phase

A chemosensitivity study of colorectal cancer using xenografts of patient-derived tumor-initiating cells

Maekawa, H., Miyoshi, H., Yamaura, T., Itatani, Y., Kawada, K., Sakai, Y. & Taketo, M. M., Oct 1 2018, In : Molecular Cancer Therapeutics. 17, 10, p. 2187-2196 10 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Heterografts
Colorectal Neoplasms
Neoplasms
Compassionate Use Trials

Achieving gender equity in the radiation oncology physician workforce

Holliday, E. B., Siker, M., Chapman, C. H., Jagsi, R., Bitterman, D. S., Ahmed, A. A., Winkfield, K., Kelly, M., Tarbell, N. J. & Deville, C., Oct 1 2018, In : Advances in Radiation Oncology. 3, 4, p. 478-483 6 p.

Research output: Contribution to journalArticle

Radiation Oncology
Physicians
Medicine

A clinical-radiomics nomogram for the preoperative prediction of lung metastasis in colorectal cancer patients with indeterminate pulmonary nodules

Hu, T. D., Wang, S. P., Huang, L., Wang, J. Z., Shi, D. B., Li, Y., Tong, T. & Peng, W., Jun 12 2018, (Accepted/In press) In : European Radiology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Nomograms
Colorectal Neoplasms
Neoplasm Metastasis
Lung
Area Under Curve

A clinical trial for Kienböck disease by cultured autologous multipotent mesenchymal stromal cells augmented with vascularized bone grafts: A report of five cases

Ikeguchi, R., Aoyama, T., Kakinoki, R., Ueda, M., Kasai, Y., Maekawa, T., Tada, H., Yamamoto, M., Matsuda, S., Nakamura, T. & Toguchida, J., Jan 1 2018, (Accepted/In press) In : Journal of Orthopaedic Science.

Research output: Contribution to journalArticle

Osteonecrosis
Mesenchymal Stromal Cells
Clinical Trials
Transplants
Bone and Bones
1 Citations

A combination of approved antibodies overcomes resistance of lung cancer to osimertinib by blocking bypass pathways

Romaniello, D., Mazzeo, L., Mancini, M., Marrocco, I., Noronha, A., Kreitman, M., Srivastava, S., Ghosh, S., Lindzen, M., Salame, T. M., Onn, A., Bar, J. & Yarden, Y., Nov 15 2018, In : Clinical Cancer Research. 24, 22, p. 5610-5621 12 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Antibodies
Drug Resistance
Protein-Tyrosine Kinases
Apoptosis