Find Research Outputs

1964
4 Citations (Scopus)

LEUKEMIA.

FREI, E. & FREIREICH, E. J., May 1964, In : Scientific American. 210, p. 88-96 9 p.

Research output: Contribution to journalArticle

Lymphoid Leukemia
Oncogenic Viruses
Myeloid Leukemia
Bone Marrow Transplantation
Methotrexate
1 Citation (Scopus)

Paper electrophoresis of cerebrospinal fluid proteins in patients with meningeal leukemia

Rothman, A. R., Carbone, P. P., Rieselbach, R. & Freireich, E. J., Jan 1 1964, In : Cancer. 17, 6, p. 798-802 5 p.

Research output: Contribution to journalArticle

Paper Electrophoresis
Cerebrospinal Fluid Proteins
Meninges
Neurologic Manifestations
Hodgkin Disease
4 Citations (Scopus)

Platelet Therapy and Red Cell Defect In Aplastic Anemia

Levin, R. H., Barrett, P. V. D., Cline, M. J., Berlin, N. I. & Freireich, E. J., 1964, In : Archives of Internal Medicine. 114, 2, p. 278-283 6 p.

Research output: Contribution to journalArticle

Aplastic Anemia
Splenectomy
Cell- and Tissue-Based Therapy
Corticosterone
Blood Transfusion
36 Citations (Scopus)

RECENT ADVANCES IN ACUTE LEUKEMIA.

FREIREICH, E. J. & FREI, E., 1964, In : Progress in hematology. 4, p. 187-202 16 p.

Research output: Contribution to journalReview article

Antineoplastic Agents
Toxicology
Leukemia
Drug Therapy
1 Citation (Scopus)

Replacement transfusion therapy of thrombocytopenia and leukopenia.

Freireich, E. J., 1964, In : Proceedings. National Cancer Conference. 5, p. 659-661 3 p.

Research output: Contribution to journalArticle

Leukopenia
Blood Transfusion
Thrombocytopenia
Lymphoma
Leukemia

Role of nucleolar ribonucleic acid in incorporation of ribosomal amino-acid

Brentani, M. M. C., Brentani, R. R. & Raw, I., Dec 1 1964, In : Nature. 201, 4924, 1 p.

Research output: Contribution to journalArticle

Carbon Isotopes
Nucleoproteins
Valine
Ribonucleases
Cell Nucleus
1 Citation (Scopus)

Supportive therapy in acute leukemia

Freireich, E. J., Jan 1 1964, In : CA: A Cancer Journal for Clinicians. 14, 6, p. 257-260 4 p.

Research output: Contribution to journalArticle

Kidney Diseases
Toxicology
Leukemia
Hemorrhage
Neoplasms

The control of behavior output as related to the concept of activation

Sines, J. O., Adkins, J. & Cleeland, C., Jan 1 1964, In : Journal of Genetic Psychology. 104, 1, p. 99-104 6 p.

Research output: Contribution to journalArticle

Animal Behavior
Behavior Control
Chlorpromazine
Sodium Chloride
activation
112 Citations (Scopus)

THE FUNCTION AND FATE OF TRANSFUSED LEUKOCYTES FROM DONORS WITH CHRONIC MYELOCYTIC LEUKEMIA IN LEUKOPENIC RECIPIENTS

Freireich, E. J., Levin, R. H., Whang, J., Carbone, P. P., Bronson, W. & Morse, E. E., Jan 1 1964, In : Annals of the New York Academy of Sciences. 113, 2, p. 1081-1089 9 p.

Research output: Contribution to journalArticle

Metaraminol
Polymyxins
Pseudomonas Infections
Myeloid Leukemia
Leukopenia
71 Citations (Scopus)

Uric acid excretion and renal function in the acute hyperuricemia of leukemia. Pathogenesis and therapy of uric acid nephropathy

Rieselbach, R. E., Bentzel, C. J., Cotlove, E., Frei, E. & Freireich, E. J., Dec 1 1964, In : The American Journal of Medicine. 37, 6, p. 872-884 13 p.

Research output: Contribution to journalArticle

Hyperuricemia
Uric Acid
Leukemia
Therapeutics
Urine
1963
10 Citations (Scopus)

Different patterns of remission in acute myelocytic leukemia. A comparison of the effects of methyl-glyoxal-bis-guanylhydrazone and 6-mercaptopurine.

LEVIN, R. H., BRITTIN, G. M. & FREIREICH, E. J., Jun 1963, In : Blood. 21, p. 689-698 10 p.

Research output: Contribution to journalArticle

6-Mercaptopurine
Myeloid Leukemia
Acute Myeloid Leukemia
Antineoplastic Agents
glyoxal bis(guanylhydrazone)
38 Citations (Scopus)

FOLIC ACID ANTAGONIST. EFFECTS ON THE CELL AND THE PATIENT. COMBINED CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH.

BERLIN, N. I., RALL, D., MEAD, J. A., Freireich, E. J., VANSCOTT, E., HERTZ, R. & LIPSETT, M. B., Dec 1 1963, In : Annals of Internal Medicine. 59, p. 931-956 26 p.

Research output: Contribution to journalArticle

Biochemical Phenomena
Trophoblastic Neoplasms
Folic Acid Antagonists
Lymphoid Leukemia
Choriocarcinoma
10 Citations (Scopus)

Intrathecal Aminopterin Therapy of Meningeal Leukemia

Rieselbach, R. E., Morse, E. E., Rall, D. P., Frei, E. & Freireich, E. J., 1963, In : Archives of Internal Medicine. 111, 5, p. 620-630 11 p.

Research output: Contribution to journalArticle

Aminopterin
Lymphoid Leukemia
Meninges
Leucovorin
Methotrexate
36 Citations (Scopus)

Persistent mitosis of transfused homologous leukocytes in children receiving antileukemic therapy

Levin, R. H., Whang, J., Tjio, J. H., Carbone, P. P., Frei, E. & Freireich, E. J., Jan 1 1963, In : Science. 142, 3597, p. 1311-1313 3 p.

Research output: Contribution to journalArticle

Philadelphia Chromosome
Cytogenetic Analysis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Blood Donors
Genetic Markers

PERSISTENT MITOSIS OF TRANSFUSED HOMOLOGOUS LEUKOCYTES IN CHILDREN RECEIVING ANTILEUKEMIC THERAPY.

LEVIN, R. H., WHANG, J., TJIO, J. H., CARBONE, P. P., FREI, E. & FREIREICH, E. J., Dec 6 1963, In : Science. 142, p. 1305-1311 7 p.

Research output: Contribution to journalArticle

Lymphoid Leukemia
Mitosis
Cell Division
Antineoplastic Agents
Leukemia
87 Citations (Scopus)

RESPONSE TO REPEATED PLATELET TRANSFUSION FROM THE SAME DONOR.

FREIREICH, E. J., KLIMAN, A., GAYDOS, L. A., MANTEL, N. & FREI, E., Jan 1 1963, In : Annals of Internal Medicine. 59, p. 277-287 11 p.

Research output: Contribution to journalArticle

Platelet Transfusion
Rhabdomyosarcoma
Blood Donors
Blood Transfusion
Thrombocytopenia
7 Citations (Scopus)

The behavior of normal and stomach lesion susceptible rats in several learning situations

Sines, J. O., Cleeland, C. & Adkins, J., Jan 1 1963, In : Journal of Genetic Psychology. 102, 1, p. 91-94 4 p.

Research output: Contribution to journalArticle

learning situation
Stomach
Learning
1962
16 Citations (Scopus)

A study of the explicit distribution of radiation in interstitial

FLETCHER, G. H. & Stovall, M., Jan 1 1962, In : Radiology. 78, p. 766-782 17 p.

Research output: Contribution to journalArticle

Tongue Neoplasms
Mouth Neoplasms
Radiotherapy
Radiation
4 Citations (Scopus)

A study of the explicit distribution of radiation in interstitial implanations. I. A method of calculation with an automatic digital computer.

STOVALL, M. & SHALEK, R. J., Jan 1 1962, In : Radiology. 78, p. 950-954 5 p.

Research output: Contribution to journalArticle

Radiometry
Automatic Data Processing
Radiation

A symposium on cancer chemotherapy. IV. Acute leukemia.

FREIREICH, E. J., Dec 1962, In : The Medical annals of the District of Columbia. 31, p. 675-682 8 p.

Research output: Contribution to journalArticle

Leukemia
Drug Therapy
Neoplasms
9 Citations (Scopus)

Correlations of the biochemical and clinical effects of 6-azauridine in patients with leukemia

Fallon, H. J., Frei, E. & Freireich, E. J., Jan 1 1962, In : The American journal of medicine. 33, 4, p. 526-537 12 p.

Research output: Contribution to journalArticle

Azauridine
Orotic Acid
Leukemia
Leukocytes
Acute Disease
3 Citations (Scopus)

Factors influencing patient selection for chemotherapy studies of acute leukemia

Freireich, E. J., Jan 1 1962, In : Journal of Chronic Diseases. 15, 3, p. 251-257 7 p.

Research output: Contribution to journalArticle

Patient Selection
Leukemia
Drug Therapy
Age Factors
Survival

Factors influencing patient selection for chemotherapy studies of acute leukemia.

FREIREICH, E. J., Feb 1 1962, In : Cancer chemotherapy reports. Part 1. 16, p. 79-87 9 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
Patient Selection
Leukemia
Drug Therapy
2 Citations (Scopus)

Importance of bulk flow in the exchange of compounds across the blood cerebrospinal fluid barrier

Rothman, A. R., Gaskins, J. R., Freireich, E. J. & Rall, D. P., Dec 1 1962, In : Nature. 193, 4813, p. 383-385 3 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Inulin
Molecular Weight
Lipids
Acids
45 Citations (Scopus)

Methylglyoxal bis (guanylhydrazone): a new agent active against acute myelocytic leukemia.

FREIREICH, E. J., FREI, E. & KARON, M., Feb 1962, In : Cancer chemotherapy reports. Part 1. 16, p. 183-186 4 p.

Research output: Contribution to journalArticle

Mitoguazone
Hydrazines
Amidines
Myeloid Leukemia
Acute Myeloid Leukemia
130 Citations (Scopus)

Subarachnoid distribution of drugs after lumbar injection.

RIESELBACH, R. E., DI CHIRO, G., FREIREICH, E. J. & RALL, D. P., Jan 1 1962, In : The New England journal of medicine. 267, p. 1273-1278 6 p.

Research output: Contribution to journalArticle

Subarachnoid Space
Injections
Pharmaceutical Preparations
340 Citations (Scopus)

The quantitative relation between platelet count and hemorrhage in patients with acute leukemia.

GAYDOS, L. A., FREIREICH, E. J. & MANTEL, N., Jan 1 1962, In : The New England journal of medicine. 266, p. 905-909 5 p.

Research output: Contribution to journalArticle

Platelet Count
Thrombocytopenia
Leukemia
Hemorrhage
9 Citations (Scopus)

Treatment of meningeal leukemia with intrathecal aminopterin.

RIESELBACH, R. E., MORSE, E. E., RALL, D. P., FREI, E. & FREIREICH, E. J., Feb 1962, In : Cancer chemotherapy reports. Part 1. 16, p. 191-196 6 p.

Research output: Contribution to journalArticle

Aminopterin
Meninges
Leukemia
1961

A clinical trial of sarcolysin in acute leukemia.

HAYES, D. M., SPURR, C. L., SCHROEDER, L. R. & FREIREICH, E. J., Jun 1961, In : Cancer chemotherapy reports. Part 1. 12, p. 153-155 3 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
Leukemia
Clinical Trials
3 Citations (Scopus)

Alkaline ribonuclease activity increase in rat kidney cortex and liver after trypan blue and other azo dyes administration.

RABINOVITCH, M., Brentani, R. R., FERREIRA, S., FAUSTO, N. & MAACK, T., May 1 1961, In : The Journal of biophysical and biochemical cytology. 10, p. 105-112 8 p.

Research output: Contribution to journalArticle

Azo Compounds
Kidney Cortex
Trypan Blue
Ribonucleases
Kidney
2 Citations (Scopus)

Effect of estradiol on the transfer rate of small molecules into the rat uterus

Kalman, S. M., Lombrozo, M. E. & Lavis, V. R., Jan 1 1961, In : Science. 134, 3487, p. 1372-1373 2 p.

Research output: Contribution to journalArticle

Uterus
Estradiol
Sucrose
Urea
Estrogens
9 Citations (Scopus)

Exchange of inulin and dextran between blood and cerebrospinal fluid

ROTHMAN, A. R., FREIREICH, E. J., GASKINS, J. R., PATLAK, C. S. & RALL, D. P., Dec 1 1961, In : The American journal of physiology. 201, p. 1145-1148 4 p.

Research output: Contribution to journalArticle

Inulin
Dextrans
Blood-Brain Barrier
Cerebrospinal Fluid
18 Citations (Scopus)

Repeated plasmapheresis of blood donors as a source of platelets.

KLIMAN, A., GAYDOS, L. A., SCHROEDER, L. R. & FREIREICH, E. J., Sep 1961, In : Blood. 18, p. 303-309 7 p.

Research output: Contribution to journalArticle

Plasmapheresis
Blood Donors
Blood Transfusion
Blood Platelets
10 Citations (Scopus)

The calculation of isodose distributions in interstitial implantations by a computer.

SHALEK, R. J. & Stovall, M., Jan 1 1961, In : Radiology. 76, p. 119-120 2 p.

Research output: Contribution to journalArticle

Radiotherapy
81 Citations (Scopus)

The effect of chemotherapy on acute leukemia in the human

Freireich, E. J., Gehan, E. A., Sulman, D., Boggs, D. R. & Frei, E., Jan 1 1961, In : Journal of Chronic Diseases. 14, 6, p. 593-608 16 p.

Research output: Contribution to journalArticle

Leukemia
Drug Therapy
Survival
Lymphoid Leukemia
Myeloid Leukemia
1960
79 Citations (Scopus)

A distinctive type of intracerebral hemorrhage associated with “blastic crisis” in patients with leukemia

Freireich, E. J., Thomas, L. B., Frei, E., Fritz, R. D. & Forkner, C. E., Jan 1 1960, In : Cancer. 13, 1, p. 146-154 9 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Leukemia
11 Citations (Scopus)

Evaluation of a new chemotherapeutic agent in patients with 'advanced refractory' acute leukemia. Studies of 6-azauracil.

FREIREICH, E. J., FREI, E., HOLLAND, J. F., PINKEL, D., SELAWRY, O., ROTHBERG, H., HAURANI, F., TAYLOR, R. & GEHAN, E. A., Sep 1 1960, In : Blood. 16, p. 1268-1278 11 p.

Research output: Contribution to journalArticle

Uracil
Refractory materials
azauracil
2 Citations (Scopus)

Increase in 'alkaline' ribonuclease of rat kidney cortex after lysozyme and egg-white administration

Maack, T., Brentani, R. R. & Rabinovitch, M., Dec 1 1960, In : Nature. 186, 4719, 1 p.

Research output: Contribution to journalArticle

Kidney Cortex
Egg White
Ribonucleases
Muramidase
Kidney Glomerulus
2 Citations (Scopus)

Investigations in acute leukemia.

BURCHENAL, J. H., HEYN, R., SUTOW, W. W., Freireich, E. J., WHITTINGTON, R. & LOUIS, J., Aug 1 1960, In : National Cancer Institute monograph. 3, p. 149-168 20 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Meningeal leukemia: A syndrome resulting from increased intracranial pressure in patients with acute leukemia

Shaw, R. K., Moore, E. W., Freireich, E. J. & Thomas, L. B., 1960, In : Neurology. 10, 9, p. 823-833 11 p.

Research output: Contribution to journalArticle

Syndrome
68 Citations (Scopus)

The Central Nervous System in Acute Leukemia: A Postmortem Study of 117 Consecutive Cases, with Particular Reference to Hemorrhages, Leukemic Infiltrations, and the Syndrome of Meningeal Leukemia

Moore, E. W., Thomas, L. B., Shaw, R. K. & Freireich, E. J., Jan 1 1960, In : A.M.A Archives of Internal Medicine. 105, 3, p. 451-468 18 p.

Research output: Contribution to journalArticle

Leukemic Infiltration
Central Nervous System Diseases
Leukemia
Central Nervous System
Hemorrhage
1959
16 Citations (Scopus)

A comparative study of the effect of transfusion of fresh and preserved whole blood on bleeding in patients with acute leukemia.

FREIREICH, E. J., SCHMIDT, P. J., SCHNEIDERMAN, M. A. & FREI, E., Jan 1 1959, In : The New England journal of medicine. 260, 1, p. 6-11 6 p.

Research output: Contribution to journalArticle

Blood Transfusion
Leukemia
Hemorrhage
6 Citations (Scopus)

Inactivation of serum ribonuclease by the kidney.

DOHI, S. R., TERZIAN, J. F., WIDMAN, A., Brentani, R. R., FAUSTO, N., LIBERMAN, B. & RABINOVITCH, M., Apr 1 1959, In : The American journal of physiology. 196, 4, p. 924-926 3 p.

Research output: Contribution to journalArticle

Ribonucleases
Kidney
Serum
52 Citations (Scopus)

The association of fatal intracranial hemorrhage and blastic crisis in patients with acute leukemia.

FRITZ, R. D., FORKNER, C. E., FREIREICH, E. J., FREI, E. & THOMAS, L. B., Jan 1 1959, In : The New England journal of medicine. 261, 2, p. 59-64 6 p.

Research output: Contribution to journalArticle

Intracranial Hemorrhages
Leukocytosis
Cerebral Hemorrhage
Leukemia
1958
79 Citations (Scopus)

A comparative study of two regimens of combination chemotherapy in acute leukemia.

FREI, E., HOLLAND, J. F., SCHNEIDERMAN, M. A., PINKEL, D., SELKIRK, G., Freireich, E. J., SILVER, R. T., GOLD, G. L. & REGELSON, W., Dec 1 1958, In : Blood. 13, 12, p. 1126-1148 23 p.

Research output: Contribution to journalArticle

Folic Acid Antagonists
6-Mercaptopurine
Chemotherapy
1957
29 Citations (Scopus)

Radioactive iron metabolism and erythrocyte survival studies of the mechanism of the anemia associated with rheumatoid arthritis.

Freireich, E. J., ROSS, J. F., BAYLES, T. B., EMERSON, C. P. & FINCH, S. C., Jan 1 1957, In : The Journal of clinical investigation. 36, 7, p. 1043-1058 16 p.

Research output: Contribution to journalArticle

Erythrocyte Aging
Anemia
Rheumatoid Arthritis
Iron
6 Citations (Scopus)

The radiation distribution and dose specification in volume implants of radioactive seeds.

SHALEK, R. J., STOVALL, M. A. & SAMPIERE, V. A., May 1957, In : The American journal of roentgenology, radium therapy, and nuclear medicine. 77, 5, p. 863-868 6 p.

Research output: Contribution to journalArticle

Isotopes
Seeds
Radiation
9 Citations (Scopus)

Tongue worm (Linguatula serrata) infestation in a patient with acute leukemia

TOBIE, J. E., EDGCOMB, J. H. & Freireich, E. J., Dec 1 1957, In : American Journal of Clinical Pathology. 28, 6, p. 628-633 6 p.

Research output: Contribution to journalArticle

Pentastomida
Mites
Leukemia
Infection
1955
28 Citations (Scopus)

Intracranial hemangiopericytomas in children

Herzog, C. E., Leeds, N. E., Bruner, J. M. & Baumgartner, J. E., Jan 1 1955, In : Pediatric Neurosurgery. 22, 5, p. 274-279 6 p.

Research output: Contribution to journalArticle

Hemangiopericytoma
Neoplasms