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2020
Open Access

Anatomic Resection Is Not Required for Colorectal Liver Metastases with RAS Mutation

Joechle, K., Vreeland, T. J., Vega, E. A., Okuno, M., Newhook, T. E., Panettieri, E., Chun, Y. S., Tzeng, C. W. D., Aloia, T. A., Lee, J. E. & Vauthey, J. N., May 1 2020, In : Journal of Gastrointestinal Surgery. 24, 5, p. 1033-1039 7 p.

Research output: Contribution to journalArticle

Ancestry-specific predisposing germline variants in cancer

Oak, N., Cherniack, A. D., Mashl, R. J., Carrot-Zhang, J., Chambwe, N., Damrauer, J. S., Knijnenburg, T. A., Robertson, A. G., Yau, C., Zhou, W., Berger, A. C., Newberg, J., Romanel, A., Sayaman, R. W., Demichelis, F., Felau, I., Frampton, G., Han, S., Hoadley, K. A., Kemal, A. & 25 others, Laird, P. W., Lazar, A. J., Le, X., Shen, H., Wong, C. K., Zenklusen, J. C., Ziv, E., Aguet, F., Demchok, J. A., Mensah, M. K. A., Tarnuzzer, R., Wang, Z., Yang, L., Alfoldi, J., Karczewski, K. J., MacArthur, D. G., Frampton, G. M., Benz, C., Stuart, J. M., Hirsch, F. R., Ding, L., Beroukhim, R., Gümüş, Z. H., Plon, S. E. & Huang, K. L., May 29 2020, In : Genome medicine. 12, 1, 51.

Research output: Contribution to journalArticle

Open Access

Androgen receptor enhances the efficacy of sorafenib against hepatocellular carcinoma through enriched EpCAM stemness

Lai, H. C., Chung, W. M., Chang, C. M., Liao, P. Y., Su, Y. T., Yeh, C. C., Jeng, L. B., Ma, W. L. & Chang, W. C., Jan 1 2020, In : Anticancer research. 40, 3, p. 1285-1295 11 p.

Research output: Contribution to journalArticle

Androgen receptor reverses the oncometabolite R-2-hydroxyglutarate-induced prostate cancer cell invasion via suppressing the circRNA-51217/miRNA-646/TGFβ1/p-Smad2/3 signaling

Xu, H., Sun, Y., You, B., Huang, C. P., Ye, D. & Chang, C., Mar 1 2020, In : Cancer Letters. 472, p. 151-164 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Andrographolide mitigates cardiac apoptosis to provide cardio-protection in high-fat-diet-induced obese mice

Lin, K. H., Marthandam Asokan, S., Kuo, W. W., Hsieh, Y. L., Lii, C. K., Viswanadha, V., Lin, Y. L., Wang, S., Yang, C. & Huang, C. Y., Jan 1 2020, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

An emerging focus on lipids in extracellular vesicles

Skotland, T., Sagini, K., Sandvig, K. & Llorente, A., Jan 1 2020, (Accepted/In press) In : Advanced Drug Delivery Reviews.

Research output: Contribution to journalArticle

Open Access

An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation

Dai, S., Horton, J. R., Wilkinson, A. W., Gozani, O., Zhang, X. & Cheng, X., Feb 28 2020, In : Journal of Biological Chemistry. 295, 9, p. 2582-2589 8 p.

Research output: Contribution to journalArticle

Open Access

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

Escala-Garcia, M., Abraham, J., Andrulis, I. L., Anton-Culver, H., Arndt, V., Ashworth, A., Auer, P. L., Auvinen, P., Beckmann, M. W., Beesley, J., Behrens, S., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Børresen-Dale, A. L., Brauch, H. & 125 others, Brenner, H., Brucker, S. Y., Burwinkel, B., Caldas, C., Canzian, F., Chang-Claude, J., Chanock, S. J., Chin, S. F., Clarke, C. L., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Dennis, J., Devilee, P., Dunn, J. A., Dunning, A. M., Dwek, M., Earl, H. M., Eccles, D. M., Eliassen, A. H., Ellberg, C., Evans, D. G., Fasching, P. A., Figueroa, J., Flyger, H., Gago-Dominguez, M., Gapstur, S. M., García-Closas, M., García-Sáenz, J. A., Gaudet, M. M., George, A., Giles, G. G., Goldgar, D. E., González-Neira, A., Grip, M., Guénel, P., Guo, Q., Haiman, C. A., Håkansson, N., Hamann, U., Harrington, P. A., Hiller, L., Hooning, M. J., Hopper, J. L., Howell, A., Huang, C. S., Huang, G., Hunter, D. J., Jakubowska, A., John, E. M., Kaaks, R., Kapoor, P. M., Keeman, R., Kitahara, C. M., Koppert, L. B., Kraft, P., Kristensen, V. N., Lambrechts, D., Le Marchand, L., Lejbkowicz, F., Lindblom, A., Lubiński, J., Mannermaa, A., Manoochehri, M., Manoukian, S., Margolin, S., Martinez, M. E., Maurer, T., Mavroudis, D., Meindl, A., Milne, R. L., Mulligan, A. M., Neuhausen, S. L., Nevanlinna, H., Newman, W. G., Olshan, A. F., Olson, J. E., Olsson, H., Orr, N., Peterlongo, P., Petridis, C., Prentice, R. L., Presneau, N., Punie, K., Ramachandran, D., Rennert, G., Romero, A., Sachchithananthan, M., Saloustros, E., Sawyer, E. J., Schmutzler, R. K., Schwentner, L., Scott, C., Simard, J., Sohn, C., Southey, M. C., Swerdlow, A. J., Tamimi, R. M., Tapper, W. J., Teixeira, M. R., Terry, M. B., Thorne, H., Tollenaar, R. A. E. M., Tomlinson, I., Troester, M. A., Truong, T., Turnbull, C., Vachon, C. M., van der Kolk, L. E., Wang, Q., Winqvist, R., Wolk, A., Yang, X. R., Ziogas, A., Pharoah, P. D. P., Hall, P., Wessels, L. F. A., Chenevix-Trench, G., Bader, G. D., Dörk, T., Easton, D. F., Canisius, S. & Schmidt, M. K., Dec 1 2020, In : Nature communications. 11, 1, 312.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

An evaluation of apalutamide for the treatment of prostate cancer

Boukovala, M., Spetsieris, N. & Efstathiou, E., 2020, (Accepted/In press) In : Expert opinion on pharmacotherapy.

Research output: Contribution to journalArticle

A new approach to modeling the microdosimetry of proton therapy beams

Abolfath, R., Helo, Y., Carlson, D. J., Stewart, R., Grosshans, D. & Mohan, R., Jul 1 2020, In : Medical physics. 47, 7, p. 3184-3190 7 p.

Research output: Contribution to journalArticle

A new immunological prognostic model based on immunohistochemistry for extranodal natural killer/T-cell lymphoma patients after non-anthracycline-based chemotherapy

Lam, S. T., Huang, H., Fang, X., Wang, Z., Hong, H., Ren, Q., Tian, Y., Lin, S. & Lin, T., 2020, In : Cancer Management and Research. 12, p. 1981-1990 10 p.

Research output: Contribution to journalArticle

Open Access

A new model incorporating axillary ultrasound after neoadjuvant chemotherapy to predict non-sentinel lymph node metastasis in invasive breast cancer

Zhang, K., Zhu, Q., Sheng, D., Li, J. & Chang, C., Jan 1 2020, In : Cancer Management and Research. 12, p. 965-972 8 p.

Research output: Contribution to journalArticle

Open Access

A new series of Invited Reviews on WHO tumor classification

Plass, C., Jun 15 2020, In : International journal of cancer. 146, 12, 1 p.

Research output: Contribution to journalEditorial

Open Access

A New World of Biomarkers and Therapeutics for Female Reproductive System and Breast Cancers: Circular RNAs

Tran, A. M., Chalbatani, G. M., Berland, L., Cruz De los Santos, M., Raj, P., Jalali, S. A., Gharagouzloo, E., Ivan, C., Dragomir, M. P. & Calin, G. A., Mar 9 2020, In : Frontiers in Cell and Developmental Biology. 8, 50.

Research output: Contribution to journalReview article

Open Access

An exercise oncology clinical pathway: Screening and referral for personalized interventions

Stout, N. L., Brown, J. C., Schwartz, A. L., Marshall, T. F., Campbell, A. M., Nekhlyudov, L., Zucker, D. S., Basen-Engquist, K. M., Campbell, G., Meyerhardt, J., Cheville, A. L., Covington, K. R., Ligibel, J. A., Sokolof, J. M., Schmitz, K. H. & Alfano, C. M., Jun 15 2020, In : Cancer. 126, 12, p. 2750-2758 9 p.

Research output: Contribution to journalComment/debate

ANG1005, a Brain-Penetrating Peptide–Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases

Kumthekar, P., Tang, S. C., Brenner, A. J., Kesari, S., Piccioni, D. E., Anders, C., Carrillo, J., Chalasani, P., Kabos, P., Puhalla, S., Tkaczuk, K., Garcia, A. A., Ahluwalia, M. S., Wefel, J. S., Lakhani, N. & Ibrahim, N., Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2789-2799 11 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
Open Access
1 Scopus citations

Angioimmunoblastic T-cell lymphoma in Taiwan reveals worse progression-free survival for RHOA G17V mutated subtype

Hsu, Y. T., Wang, Y. C., Chen, R. Y., Hung, L. Y., Li, S. S., Yen, C. C., Chen, T. Y., Medeiros, L. J. & Chang, K. C., Apr 15 2020, In : Leukemia and Lymphoma. 61, 5, p. 1108-1118 11 p.

Research output: Contribution to journalArticle

An improved method for analyzing and reporting patterns of in-field recurrence after stereotactic ablative radiotherapy in early-stage non-small cell lung cancer

Nantavithya, C., Gomez, D. R., Chang, J. Y., Mohamed, A. S. R., Fuller, C. D., Li, H., Brooks, E. D. & Gandhi, S. J., Apr 2020, In : Radiotherapy and Oncology. 145, p. 209-214 6 p.

Research output: Contribution to journalArticle

Open Access

An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue

Jin, J., Xu, Y., Huo, L., Ma, L., Scott, A. W., Pizzi, M. P., Li, Y., Wang, Y., Yao, X., Song, S. & Ajani, J. A., 2020, In : PloS one. 15, 2, e0228910.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An inflammatory imposter: Three cases of Mullerian carcinoma appearing as inflammatory breast cancer

Grant, S. R., Krishnamurthy, S., Le-Petross, C., Valero, V., Teshome, M. & Woodward, W. A., May 1 2020, In : Breast Journal. 26, 5, p. 1022-1024 3 p.

Research output: Contribution to journalComment/debate

An international multicenter retrospective analysis of patients with extranodal marginal zone lymphoma and histologically confirmed central nervous system and dural involvement

Sunderland, A. J., Steiner, R. E., Al Zahrani, M., Pinnix, C. C., Dabaja, B. S., Gunther, J. R., Nastoupil, L. J., Jerkeman, M., Joske, D., Cull, G., El-Galaly, T., Villa, D. & Cheah, C. Y., Jan 1 2020, In : Cancer medicine. 9, 2, p. 663-670 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An international survey about rapid sequence intubation of 10,003 anaesthetists and 16 airway experts

Zdravkovic, M., Berger-Estilita, J., Sorbello, M. & Hagberg, C. A., Mar 1 2020, In : Anaesthesia. 75, 3, p. 313-322 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

An interobserver reproducibility analysis of size-set semiautomatic counting for Ki67 assessment in breast cancer

Wang, Y. X., Wang, Y. Y., Yang, C. G., Bu, H., Yang, W. T., Wang, L., Xu, W. M., Zhao, X. L., Zhao, W. X., Li, L., Song, S. L. & Yang, J. L., Feb 2020, In : Breast. 49, p. 225-232 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

An inverse association between the Mediterranean diet and bladder cancer risk: a pooled analysis of 13 cohort studies

Witlox, W. J. A., van Osch, F. H. M., Brinkman, M., Jochems, S., Goossens, M. E., Weiderpass, E., White, E., van den Brandt, P. A., Giles, G. G., Milne, R. L., Huybrechts, I., Adami, H. O., Bueno-de-Mesquita, B., Wesselius, A. & Zeegers, M. P., Feb 1 2020, In : European Journal of Nutrition. 59, 1, p. 287-296 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis

Hight, S. K., Mootz, A., Kollipara, R. K., McMillan, E., Yenerall, P., Otaki, Y., Li, L. S., Avila, K., Peyton, M., Rodriguez-Canales, J., Mino, B., Villalobos, P., Girard, L., Dospoy, P., Larsen, J., White, M. A., Heymach, J. V., Wistuba, I. I., Kittler, R. & Minna, J. D., Aug 2020, In : Neoplasia (United States). 22, 8, p. 294-310 17 p.

Research output: Contribution to journalArticle

Open Access

Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites

Kabe, Y., Takemoto, D., Kanai, A., Hirai, M., Ono, Y., Akazawa, S., Horikawa, M., Kitagawa, Y., Handa, H., Rogi, T., Shibata, H. & Suematsu, M., Dec 1 2020, In : npj Science of Food. 4, 1, 4.

Research output: Contribution to journalArticle

Open Access

Annexin-coated particles induce antigen-specific immunosuppression

Link, C., Bujupi, F., Krammer, P. H. & Weyd, H., Feb 17 2020, In : Autoimmunity. 53, 2, p. 86-94 9 p.

Research output: Contribution to journalArticle

Announcement: The International System for Reporting Lymph Node Cytopathology

Zeppa, P., Cozzolino, I., Caraway, N. P., Al-Abbadi, M. A., Barroca, H., Bode-Lesniewska, B., Calaminici, M., Chhieng, D. F., Ehinger, M., Geddie, W. R., Katz, R. L., Lin, O., Medeiros, L. J., Monaco, S. E., Rajwanshi, A., Schmitt, F. C., Vielh, P. & Field, A. S., Jan 1 2020, (Accepted/In press) In : Acta Cytologica.

Research output: Contribution to journalReview article

An observational study on long-term renal outcome in patients with chronic hepatitis B treated with tenofovir disoproxil fumarate

Lim, T. S., Lee, J. S., Kim, B. K., Lee, H. W., Jeon, M. Y., Kim, S. U., Park, J. Y., Kim, D. Y., Han, K. H. & Ahn, S. H., Mar 1 2020, In : Journal of Viral Hepatitis. 27, 3, p. 316-322 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An Odyssey into the Land of Deleterious Rare Mutations in Colorectal Liver Metastases

Newhook, T. E., Chun, Y. S. & Vauthey, J. N., 2020, (Accepted/In press) In : Annals of surgical oncology.

Research output: Contribution to journalComment/debate

Open Access

A nomogram to predict survival of patients with intermediate-stage hepatocellular carcinoma after transarterial chemoembolization combined with microwave ablation

Ni, J. Y., Fang, Z. T., Sun, H. L., An, C., Huang, Z. M., Zhang, T. Q., Jiang, X. Y., Chen, Y. T., Xu, L. F. & Huang, J. H., Apr 1 2020, In : European Radiology. 30, 4, p. 2377-2390 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

An open invitation to join the Pediatric Proton/Photon Consortium Registry to standardize data collection in pediatric radiation oncology

Lawell, M. P., Indelicato, D. J., Paulino, A. C., Hartsell, W., Laack, N. N., Ermoian, R. P., Perentesis, J. P., Vatner, R., Perkins, S., Mangona, V. S., Hill-Kayser, C. E., Wolden, S. L., Kwok, Y., Chang, J. H. C., Wilkinson, J. B., MacEwan, I., Chang, A. L., Eaton, B. R., Ladra, M. M., Gallotto, S. L. & 6 others, Weyman, E. A., Bajaj, B. V. M., Baliga, S., Yeap, B. Y., Berrington de Gonzalez, A. & Yock, T. I., Mar 1 2020, In : The British journal of radiology. 93, 1107, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

An open label, multicenter, noninterventional study of apatinib in advanced gastric cancer patients (AHEAD-G202)

Wang, X., Zhang, R., Du, N., Yang, M., Zang, A., Liu, L., Yu, J., Gao, J., Zhang, J., Fu, Z., Ren, Y., Ma, L., Guo, J., Li, Q., Li, X., Fan, Z., Song, X., Liu, Z., Zhang, Y., Li, G. & 11 others, Yu, Z., Diao, J., Jia, J., Liang, F., Wang, H., Sun, J., Gao, Y., Yang, P., Bai, C., Ren, X. & Zhong, D., 2020, In : Therapeutic Advances in Medical Oncology. 12

Research output: Contribution to journalArticle

Open Access

An open-label, single-arm pilot study of EUS-guided brachytherapy with phosphorus-32 microparticles in combination with gemcitabine +/- nab-paclitaxel in unresectable locally advanced pancreatic cancer (OncoPaC-1): Technical details and study protocol

Bhutani, M. S., Klapman, J. B., Tuli, R., El-Haddad, G., Hoffe, S., Wong, F. C. L., Chasen, B., Fogelman, D. R., Lo, S. K., Nissen, N. N., Hendifar, A. E., Varadhachary, G., Katz, M. H. G., Erwin, W. D., Koay, E. J., Tamm, E. P., Singh, B. S., Mehta, R., Wolff, R. A., Soman, A. & 2 others, Cazacu, I. M. & Herman, J. M., Jan 1 2020, In : Endoscopic Ultrasound. 9, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

An optimal Bayesian predictive probability design for phase II clinical trials with simple and complicated endpoints

Guo, B. & Liu, S., Mar 1 2020, In : Biometrical Journal. 62, 2, p. 339-349 11 p.

Research output: Contribution to journalArticle

A novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies

Phillips, D. C., Jin, S., Gregory, G. P., Zhang, Q., Xue, J., Zhao, X., Chen, J., Tong, Y., Zhang, H., Smith, M., Tahir, S. K., Clark, R. F., Penning, T. D., Devlin, J. R., Shortt, J., Hsi, E. D., Albert, D. H., Konopleva, M., Johnstone, R. W., Leverson, J. D. & 1 others, Souers, A. J., Jun 1 2020, In : Leukemia. 34, 6, p. 1646-1657 12 p.

Research output: Contribution to journalArticle

Open Access

A novel clip-band traction device to facilitate colorectal endoscopic submucosal dissection and defect closure

Ge, P. S. & Aihara, H., May 2020, In : VideoGIE. 5, 5, p. 180-186 7 p.

Research output: Contribution to journalArticle

Open Access

A novel computed tomography image synthesis method for correcting the spectrum dependence of CT numbers

Chen, Y. W., Fang, H. Y., Wang, Y. C., Peng, S. L. & Shih, C. T., Jan 16 2020, In : Physics in medicine and biology. 65, 2, 025013.

Research output: Contribution to journalArticle

A novel deep learning model using dosimetric and clinical information for grade 4 radiotherapy-induced lymphopenia prediction

Zhu, C., Lin, S. H., Jiang, X., Xiang, Y., Belal, Z., Jun, G. & Mohan, R., Feb 4 2020, In : Physics in medicine and biology. 65, 3, 035014.

Research output: Contribution to journalArticle

A novel HDAC inhibitor chidamide combined with imatinib synergistically targets tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

He, B., Wang, Q., Liu, X., Lu, Z., Han, J., Pan, C., Carter, B. Z., Liu, Q., Xu, N. & Zhou, H., Sep 2020, In : Biomedicine and Pharmacotherapy. 129, 110390.

Research output: Contribution to journalArticle

Open Access

A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice

Mattiske, D., Behringer, R. R., Overbeek, P. A. & Pask, A. J., Mar 1 2020, In : Differentiation. 112, p. 1-6 6 p.

Research output: Contribution to journalArticle

A novel nomogram to predict the local tumor progression after microwave ablation in patients with early-stage hepatocellular carcinoma: A tool in prediction of successful ablation

An, C., Wu, S., Huang, Z., Ni, J., Zuo, M., Gu, Y., Zhang, T. & Huang, J., Jan 1 2020, In : Cancer medicine. 9, 1, p. 104-115 12 p.

Research output: Contribution to journalArticle

Open Access

A novel normalization for amide proton transfer CEST MRI to correct for fat signal–induced artifacts: application to human breast cancer imaging

Zimmermann, F., Korzowski, A., Breitling, J., Meissner, J. E., Schuenke, P., Loi, L., Zaiss, M., Bickelhaupt, S., Schott, S., Schlemmer, H. P., Paech, D., Ladd, M. E., Bachert, P. & Goerke, S., Mar 1 2020, In : Magnetic resonance in medicine. 83, 3, p. 920-934 15 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A novel regulator of ER Ca2+ drives Hippo-mediated tumorigenesis

Ma, X., Lu, J. Y., Moraru, A., Teleman, A. A., Fang, J., Qiu, Y., Liu, P. & Xu, T., Feb 6 2020, In : Oncogene. 39, 6, p. 1378-1387 10 p.

Research output: Contribution to journalArticle

A novel ribosomal protein S20 variant in a family with unexplained colorectal cancer and polyposis

Thompson, B. A., Snow, A. K., Koptiuch, C., Kohlmann, W. K., Mooney, R., Johnson, S., Huff, C. D., Yu, Y., Teerlink, C. C., Feng, B. J., Neklason, D. W., Cannon-Albright, L. A. & Tavtigian, S. V., Jun 1 2020, In : Clinical Genetics. 97, 6, p. 943-944 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

A novel salicylanilide derivative induces autophagy cell death in castration-resistant prostate cancer via ER stress-activated PERK signaling pathway

Hsieh, C. L., Huang, H. S., Chen, K. C., Saka, T., Chiang, C. Y., Chung, L. W. K. & Sung, S. Y., Jan 1 2020, In : Molecular cancer therapeutics. 19, 1, p. 101-111 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

A novel strategy for glioblastoma treatment combining alpha-cyano-4-hydroxycinnamic acid with cetuximab using nanotechnology-based delivery systems

Ferreira, N. N., Granja, S., Boni, F. I., Ferreira, L. M. B., Reis, R. M., Baltazar, F. & Gremião, M. P. D., Jun 1 2020, In : Drug Delivery and Translational Research. 10, 3, p. 594-609 16 p.

Research output: Contribution to journalArticle