Find Research Outputs

2019

ATRX protein loss and deregulation of PI3K/AKT pathway is frequent in pilocytic astrocytoma with anaplastic features

Olar, A., Tran, D., Mehta, V. P., Reinhardt, A., Manekia, J. H., Garnovskaya, M., Ellezam, B., Luthra, R., Sulman, E. P., Mohila, C. A., Campbell, G. A., Powell, S. Z., Fuller, G. N., Aldape, K. D. & Adesina, A. M., Mar 1 2019, In : Clinical neuropathology. 38, 2, p. 59-73 15 p.

Research output: Contribution to journalArticle

Astrocytoma
Phosphatidylinositol 3-Kinases
Neoplasms
Proteins
Immunohistochemistry
Methadone
Palliative Care
Pediatrics
Physicians
Hospices

A universal anti-cancer vaccine: Chimeric invariant chain potentiates the inhibition of melanoma progression and the improvement of survival

Sharbi-Yunger, A., Grees, M., Cafri, G., Bassan, D., Eichmüller, S. B., Tzehoval, E., Utikal, J., Umansky, V. & Eisenbach, L., Feb 15 2019, In : International Journal of Cancer. 144, 4, p. 909-921 13 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Melanoma
T-Lymphocytes
Neoplasms
Neoplasm Antigens

Author Correction: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization (Nature Cell Biology, (2018), 20, 8, (966-978), 10.1038/s41556-018-0138-8)

Er, E. E., Valiente, M., Ganesh, K., Zou, Y., Agrawal, S., Hu, J., Griscom, B., Rosenblum, M., Boire, A., Brogi, E., Giancotti, F. G., Schachner, M., Malladi, S. & Massagué, J., Mar 1 2019, In : Nature cell biology. 21, 3, 1 p.

Research output: Contribution to journalComment/debate

Pericytes
Cell Biology
Neoplasms

Author Correction: Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition (Nature Cell Biology, (2010), 12, 10, (982-992), 10.1038/ncb2099)

Yang, M. H., Hsu, D. S. S., Wang, H. W., Wang, H. J., Lan, H. Y., Yang, W-H., Huang, C. H., Kao, S. Y., Tzeng, C. H., Tai, S. K., Chang, S. Y., Lee, O. K. S. & Wu, K. J., Apr 1 2019, In : Nature cell biology. 21, 4, 1 p.

Research output: Contribution to journalComment/debate

Ficus
Cell Biology

Author Correction: The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling (Nature Cell Biology, (2014), 17, 1, (81-94), 10.1038/ncb3082)

Okada, T., Sinha, S., Esposito, I., Schiavon, G., López-Lago, M. A., Su, W., Pratilas, C. A., Abele, C., Hernandez, J. M., Ohara, M., Okada, M., Viale, A., Heguy, A., Socci, N. D., Sapino, A., Seshan, V. E., Long, S., Inghirami, G., Rosen, N. & Giancotti, F. G., Apr 1 2019, In : Nature cell biology. 21, 4, 1 p.

Research output: Contribution to journalComment/debate

rho GTP-Binding Proteins
Cell Biology
Carcinogenesis
Breast
Clone Cells
1 Citation (Scopus)
Immunotherapy
End point
Progression
Dose
Immune Response

Autologous stem cell transplantation in multiple myeloma: Post-transplant outcomes of Taiwan Blood and Marrow Transplantation Registry

Huang, T. C., Huang, S. Y., Yao, M., Lin, C-Y., Hwang, W. L., Gau, J. P., Tan, T. D., Wang, P. N., Liu, Y. C., Lin, S. C., Kao, R. H., Pei, S. N., Yu, M. S., Lin, H. Y., Su, Y. C., Chen, C. C., Li, S. S. & Wu, Y. Y., Jan 1 2019, In : Journal of the Formosan Medical Association. 118, 1P3, p. 471-480 10 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Multiple Myeloma
Taiwan
Registries
Transplantation

Automated multiplex immunofluorescence panel for immuno-oncology studies on formalin-fixed carcinoma tissue specimens

Surace, M., DaCosta, K., Huntley, A., Zhao, W., Bagnall, C., Brown, C., Wang, C., Roman, K., Cann, J., Lewis, A., Steele, K., Rebelatto, M., Parra Cuentas, E. R., Hoyt, C. C. & Rodriguez Canales, J., Jan 1 2019, In : Journal of Visualized Experiments. 2019, 143, e58390.

Research output: Contribution to journalArticle

Oncology
Formaldehyde
Fluorescent Antibody Technique
Tissue
Carcinoma

Automatic segmentation of cardiac substructures from noncontrast CT images: accurate enough for dosimetric analysis?

Luo, Y., Xu, Y., Liao, Z., Gomez, D., Wang, J., Jiang, W., Zhou, R., Williamson, R., Court, L. E. & Yang, J., Jan 2 2019, In : Acta Oncologica. 58, 1, p. 81-87 7 p.

Research output: Contribution to journalArticle

Tomography
Pulmonary Veins
Non-Small Cell Lung Carcinoma
Four-Dimensional Computed Tomography
Cardiac Volume

Availability of HLA-allele-matched unrelated donors: estimation from haplotype frequency in the Japanese population

Nishiwaki, S., Tanaka, H., Kojima, H. & Okamoto, S., Feb 1 2019, In : Bone marrow transplantation. 54, 2, p. 300-303 4 p.

Research output: Contribution to journalArticle

Unrelated Donors
HLA Antigens
Haplotypes
Alleles
Tissue Donors

Avoidable cancers in the Nordic countries—the potential impact of increased physical activity on postmenopausal breast, colon and endometrial cancer

Andersson, T. M. L., Engholm, G., Lund, A. S. Q., Lourenço, S., Matthiessen, J., Pukkala, E., Stenbeck, M., Tryggvadottir, L., Weiderpass, E. V. & Storm, H., Mar 1 2019, In : European Journal of Cancer. 110, p. 42-48 7 p.

Research output: Contribution to journalArticle

Metabolic Equivalent
Endometrial Neoplasms
Colonic Neoplasms
Scandinavian and Nordic Countries
Breast Neoplasms

A Web-based survey among adults aged 40–54 years was time effective and yielded stable response patterns

Weigl, K., Tikk, K., Hoffmeister, M., De Toni, E. N., Hampe, J., Kolligs, F., Klug, S. J., Mansmann, U., Nasseh, D., Radlovic, J., Schwab, M., Schweigler, D., Stephan, A. M. & Brenner, H., Jan 1 2019, In : Journal of Clinical Epidemiology. 105, p. 10-18 9 p.

Research output: Contribution to journalArticle

Epidemiologic Studies
Colorectal Neoplasms
Sex Distribution
Age Distribution
Colonoscopy

Axillary web syndrome: What the radiologist needs to know

Mayo III, R. C. & W. T. Leung, J., Jan 1 2019, In : Breast Journal. 25, 1, 1 p.

Research output: Contribution to journalComment/debate

Radiologists

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia

Krombholz, C. F., Gallego-Villar, L., Sahoo, S. S., Panda, P. K., Wlodarski, M. W., Aumann, K., Hartmann, M., Lipka, D. B., Daskalakis, M., Plass, C., Niemeyer, C. M., Erlacher, M. & Flotho, C., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Juvenile Myelomonocytic Leukemia
Azacitidine
Leukemia
Colorectal Neoplasms
Explosions
Protein Sequence Analysis
Computational Biology
Natural History

Back to the Future: In the Era of Cost-Effectiveness Analysis, Affordability Is a Limiting Factor for Patients’ Access to Innovative Cancer Treatments

Aguiar, P. N., Roitberg, F., Noia Barreto, C. M., Adashek, J. J., Giglio, A. D. & Lopes, G. L., Dec 1 2019, In : Value in Health Regional Issues. 20, p. 47-50 4 p.

Research output: Contribution to journalArticle

Cost-Benefit Analysis
Neoplasms
Administrative Personnel
Health Care Costs
Decision Making

Bactericidal activity of ceftaroline, vancomycin and daptomycin against methicillin-resistant Staphylococcus aureus isolates from cancer patients

Rolston, K. V. I., Jamal, M., Nesher, L., Raad, I. I., Rice, S. A., Rybak, M. J. & Prince, R. A., Jun 1 2019, In : Journal of Global Antimicrobial Resistance. 17, p. 16-18 3 p.

Research output: Contribution to journalLetter

Daptomycin
Vancomycin
Methicillin-Resistant Staphylococcus aureus
Neoplasms
T 91825

Baicalein enhances the effect of low dose Levodopa on the gait deficits and protects dopaminergic neurons in experimental Parkinsonism

Zheng, Z. V., Cheung, C. Y., Lyu, H., Chan, H. Y., Li, Y., Bian, Z. X., Wang, K. K. W. & Poon, W., Jan 1 2019, In : Journal of Clinical Neuroscience.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Parkinsonian Disorders
Levodopa
Gait
Parkinson Disease

Barriers in Latin America for the management of locally advanced breast cancer

Pinto, J. A., Pinillos, L. V., Villarreal-Garza, C., Morante, Z., Villarán, M. V., Mejía, G., Caglevic, C., Aguilar, A., Fajardo, W., Usuga, F., Carrasco, M., Rebaza, P., Posada, A. M., Tirado-Hurtado, I., Flores, C. & Vallejos, C. S., Jan 22 2019, In : ecancermedicalscience. 13, 897.

Research output: Contribution to journalArticle

Latin America
Breast Neoplasms
Neoplasms
Standard of Care
Developed Countries

Bayesian analysis of longitudinal dyadic data with informative missing data using a dyadic shared-parameter model

Ahn, J., Morita, S., Wang, W. & Yuan, Y., Jan 1 2019, In : Statistical Methods in Medical Research. 28, 1, p. 70-83 14 p.

Research output: Contribution to journalArticle

Bayes Theorem
Bayesian Analysis
Missing Data
Missing Data Mechanism
Longitudinal Studies
Bayesian Nonparametrics
Transplantation
Stem Cells
Dirichlet Process
Regression

Bayesian personalized treatment selection strategies that integrate predictive with prognostic determinants

Ma, J., Stingo, F. C. & Hobbs, B. P., Jan 1 2019, In : Biometrical Journal.

Research output: Contribution to journalArticle

Determinant
Integrate
Biomarkers
Selection Rules
Methodology
3 Citations (Scopus)

Bayesian treatment comparison using parametric mixture priors computed from elicited histograms

Thall, P. F., Ursino, M., Baudouin, V., Alberti, C. & Zohar, S., Feb 1 2019, In : Statistical Methods in Medical Research. 28, 2, p. 404-418 15 p.

Research output: Contribution to journalArticle

Histogram
Physicians
Methodology
Randomized Trial
Hyperparameters

Bayesian variable selection based on clinical relevance weights in small sample studies—Application to colon cancer

Boulet, S., Ursino, M., Thall, P. F., Jannot, A. S. & Zohar, S., Jan 1 2019, (Accepted/In press) In : Statistics in Medicine.

Research output: Contribution to journalArticle

Bayesian Variable Selection
Small Sample
Colonic Neoplasms
Variable Selection
Cancer

BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor

Jour, G., Vasudevaraja, V., Prieto, V., Snuderl, M., Torres Cabala, C. A., Al-Rohil, R., Sulman, E. P., Ballester, L. Y. & Aung, P. P., Mar 1 2019, In : Modern Pathology. 32, 3, p. 338-345 8 p.

Research output: Contribution to journalArticle

Neurilemmoma
Melanoma
Skin
Methylation
Soft Tissue Neoplasms

Becoming an engaged pathologist

Booth, A. L. & Roy Chowdhuri, S., Feb 1 2019, In : Archives of Pathology and Laboratory Medicine. 143, 2, p. 149-150 2 p.

Research output: Contribution to journalEditorial

Pathologists

Behandlungsergebnisse der Strahlentherapie beim primären Rückenmarksgliom

Choi, S. H., Yoon, H. I., Yi, S., Park, J. W., Cho, J. H., Shin, D. A., Ha, Y., Kim, D. S., Kim, S. H., Lee, S. K., Chang, J. H. & Suh, C-O., Feb 6 2019, In : Strahlentherapie und Onkologie. 195, 2, p. 164-174 11 p.

Research output: Contribution to journalArticle

Glioma
Spinal Cord
Radiotherapy
Survival
Neoplasms

Behavioral conservatism is linked to complexity of behavior in chimpanzees (Pan troglodytes): Implications for cognition and cumulative culture

Davis, S. J., Schapiro, S. J., Lambeth, S. P., Wood, L. A. & Whiten, A., Feb 1 2019, In : Journal of Comparative Psychology. 133, 1, p. 20-35 16 p.

Research output: Contribution to journalArticle

Pan troglodytes
cognition
Politics
Cognition
learning

Benefits of a Psychosocial Intervention on Positive Affect and Posttraumatic Growth for Chinese American Breast Cancer Survivors: A Pilot Study

Warmoth, K., Yeung, N. C. Y., Xie, J., Feng, H., Loh, A., Young, L. & Lu, Q., Jan 1 2019, (Accepted/In press) In : Behavioral Medicine.

Research output: Contribution to journalArticle

Asian Americans
Survivors
Breast Neoplasms
Growth
Linguistics

BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment

Piya, S., Mu, H., Bhattacharya, S., Lorenzi, P. L., Davis, R. E., McQueen, T., Ruvolo, V., Baran, N., Wang, Z., Qian, Y., Crews, C. M., Konopleava, M., Ishizawa, J., You, M. J., Kantarjian, H. M., Andreeff, M. & Borthakur, G., Feb 21 2019, In : The Journal of clinical investigation. 130

Research output: Contribution to journalArticle

Open Access
Stem Cell Niche
Acute Myeloid Leukemia
Down-Regulation
Leukemia
Stem Cells

Bevacizumab treatment for radiation brain necrosis: Mechanism, efficacy and issues

Zhuang, H., Shi, S., Yuan, Z. & Chang, J. Y., Feb 7 2019, In : Molecular cancer. 18, 1, 21.

Research output: Contribution to journalReview article

Open Access
Necrosis
Radiation
Brain
Therapeutics
Vascular Endothelial Growth Factor A
1 Citation (Scopus)

Beyond Autoantibodies: Biologic Roles of Human Autoreactive B Cells in Rheumatoid Arthritis Revealed by RNA-Sequencing

Mahendra, A., Yang, X., Abnouf, S., Adolacion, J. R. T., Park, D., Soomro, S., Roszik, J., Coarfa, C., Romain, G., Wanzeck, K., Bridges, S. L., Aggarwal, A., Qiu, P., Agarwal, S. K., Mohan, C. & Varadarajan, N., Apr 1 2019, In : Arthritis and Rheumatology. 71, 4, p. 529-541 13 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Autoantibodies
Citrulline
Rheumatoid Arthritis
B-Lymphocytes

Beyond chemotherapy: Emerging biomarkers and therapies as small cell lung cancer enters the immune checkpoint era

Della Corte, C. M., Gay, C. M. & Byers, L. A., Feb 15 2019, In : Cancer. 125, 4, p. 496-498 3 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Biomarkers
Drug Therapy
Therapeutics

Biclonal presentation of lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia

Wang, W., Ding, Y., Campbell, A., Handy, B. C., Medeiros, L. J. & Lin, P., Apr 1 2019, In : Pathology. 51, 3, p. 340-343 4 p.

Research output: Contribution to journalLetter

Waldenstrom Macroglobulinemia
Lymphoma

Bicyclic peptides as a new modality for imaging and targeting of proteins overexpressed by tumors

Eder, M., Pavan, S., Bauder-Wüst, U., van Rietschoten, K., Baranski, A. C., Harrison, H., Campbell, S., Stace, C. L., Walker, E. H., Chen, L., Bennett, G., Mudd, G., Schierbaum, U., Leotta, K., Haberkorn, U., Kopka, K. & Teufel, D. P., Feb 15 2019, In : Cancer Research. 79, 4, p. 841-852 12 p.

Research output: Contribution to journalArticle

Protein Transport
Peptides
Matrix Metalloproteinase 14
Neoplasms
Heterografts
Parathyroidectomy
Primary Hyperparathyroidism
Quality Improvement
Neck
Parathyroid Hormone

Bilateral spontaneous pneumothoraces in anaplastic thyroid cancer

Kazzaz, F. I., Cabanillas, M. E., Bashoura, L., Shannon, V. R. & Faiz, S., Jan 1 2019, In : Respiratory Medicine Case Reports. 26, p. 197-199 3 p.

Research output: Contribution to journalArticle

Pneumothorax
Lung
Neoplasm Micrometastasis
Thyroidectomy
Receptor Protein-Tyrosine Kinases
2 Citations (Scopus)

Biliary Decompression in Perihilar Cholangiocarcinoma Improves Survival: A Single-Center Retrospective Analysis

Cassani, L. S., Chouhan, J., Chan, C., Lanke, G., Chen, H. C., Wang, X., Weston, B., Ross, W. A., Raju, G. S. & Lee, J. H., Feb 15 2019, In : Digestive diseases and sciences. 64, 2, p. 561-569 9 p.

Research output: Contribution to journalArticle

Klatskin Tumor
Decompression
Stents
Drainage
Survival

Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats

Lin, K. H., Shibu, M. A., Peramaiyan, R., Chen, Y. F., Shen, C. Y., Hsieh, Y. L., Chen, R. J., Viswanadha, V. P., Kuo, W. W. & Huang, C-Y., Jan 1 2019, In : Journal of Functional Foods. 52, p. 212-218 7 p.

Research output: Contribution to journalArticle

flavone
Cardiomegaly
flavones
hypertrophy
hypertension

Biomarker analysis of the GATSBY study of trastuzumab emtansine versus a taxane in previously treated HER2-positive advanced gastric/gastroesophageal junction cancer

Shah, M. A., Kang, Y. K., Thuss-Patience, P. C., Ohtsu, A., Ajani, J. A., Van Cutsem, E., Hoersch, S., Harle-Yge, M. L. & de Haas, S. L., Jan 1 2019, In : Gastric Cancer.

Research output: Contribution to journalArticle

Esophagogastric Junction
Stomach
Biomarkers
Survival
Neoplasms

Biomarkers of vascular injury in relation to myocardial infarction risk: A population-based study

Pletsch-Borba, L., Grafetstätter, M., Hüsing, A., González Maldonado, S., Kloss, M., Groß, M. L., Johnson, T., Sookthai, D., Bugert, P., Kaaks, R. & Kühn, T., Dec 1 2019, In : Scientific reports. 9, 1, 3004.

Research output: Contribution to journalArticle

Open Access
Vascular System Injuries
Biomarkers
Myocardial Infarction
Population
Cardiovascular Diseases
1 Citation (Scopus)

BisAMP: A web-based pipeline for targeted RNA cytosine-5 methylation analysis

Bormann, F., Tuorto, F., Cirzi, C., Lyko, F. & Legrand, C., Mar 1 2019, In : Methods. 156, p. 121-127 7 p.

Research output: Contribution to journalArticle

Methylation
Cytosine
Pipelines
RNA
Stem cells

Blinatumomab for the treatment of acute lymphoblastic leukemia: an update

Rausch, C. R., Paul, S., Nasnas, P. E., Kantarjian, H. M. & Jabbour, E. J., Feb 1 2019, In : Expert Opinion on Orphan Drugs. 7, 2, p. 41-46 6 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Philadelphia Chromosome
Therapeutics
Phase III Clinical Trials
Expert Testimony

Blood platelet function abnormalities in cirrhotic patients with esophageal varices in relation to the variceal bleeding history*

Rogalski, P., Rogalska-Plonska, M., Wroblewski, E., Kostecka-Roslen, I., Dabrowska, M., Swidnicka-Siergiejko, A. K., Wasielica-Berger, J., Cydzik, M., Hirnle, T., Dobrzycki, S., Flisiak, R. & Dabrowski, A., Jan 1 2019, In : Scandinavian Journal of Gastroenterology.

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Blood Platelets
Hemorrhage
Thrombelastography
von Willebrand Factor

Bmi1 marks gastric stem cells located in the isthmus in mice

Yoshioka, T., Fukuda, A., Araki, O., Ogawa, S., Hanyu, Y., Matsumoto, Y., Yamaga, Y., Nakanishi, Y., Kawada, K., Sakai, Y., Chiba, T. & Seno, H., Jan 1 2019, In : Journal of Pathology.

Research output: Contribution to journalArticle

Stomach
Stem Cells
Tamoxifen
Organoids
Pyloric Antrum

BNIP1 inhibits cell proliferation, migration and invasion, and promotes apoptosis by mTOR in cervical cancer cells

Li, F. H., Xiang, L., Ran, L., Zhou, S., Huang, Z., Chen, M. & Yu, W. F., Jan 1 2019, In : European review for medical and pharmacological sciences. 23, 4, p. 1397-1407 11 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Cell Movement
Cell Proliferation
Apoptosis
Lymphatic Metastasis

Body dissatisfaction and disordered eating symptoms in Finnish preadolescents

Figueiredo, R. A. D. O., Simola-Ström, S., Isomaa, R. & Weiderpass, E. V., Jan 2 2019, In : Eating Disorders. 27, 1, p. 34-51 18 p.

Research output: Contribution to journalArticle

Eating
Odds Ratio
Confidence Intervals
Thinness
Weights and Measures
1 Citation (Scopus)

Body fatness, adipose tissue compartments, and biomarkers of inflammation and angiogenesis in colorectal cancer: The ColoCare study

Himbert, C., Ose, J., Nattenmüller, J., Warby, C. A., Holowatyj, A. N., Böhm, J., Lin, T., Haffa, M., Gigic, B., Hardikar, S., Scherer, D., Zielske, L., Schrotz-King, P., Kölsch, T., Siegel, E. M., Shibata, D., Ulrich, A., Schneider, M., Hursting, S. D., Kauczor, H. U. & 1 othersUlrich, C. M., Jan 1 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 1, p. 76-82 7 p.

Research output: Contribution to journalArticle

Subcutaneous Fat
Adipose Tissue
Colorectal Neoplasms
Biomarkers
Inflammation