Find Research Outputs

2019

Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis

Wolff, G., Taranko, A. E., Meln, I., Weinmann, J., Sijmonsma, T., Lerch, S., Heide, D., Billeter, A. T., Tews, D., Krunic, D., Fischer-Posovszky, P., Müller-Stich, B. P., Herzig, S., Grimm, D., Heikenwälder, M., Kao, W. W. & Vegiopoulos, A., Jan 1 2019, In : Molecular Metabolism. 19, p. 97-106 10 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Homeostasis
Obesity
Diet
Glucose

Diet quality and Gleason grade progression among localised prostate cancer patients on active surveillance

Gregg, J. R., Zheng, J., Lopez, D. S., Reichard, C., Browman, G., Chapin, B. F., Kim, J., Davis, J. W. & Daniel-MacDougall, C. R., Jan 1 2019, (Accepted/In press) In : British journal of cancer.

Research output: Contribution to journalArticle

Differences in the efficacies of pazopanib and gemcitabine/docetaxel as second-line treatments for metastatic soft tissue sarcoma

Kim, J. H., Park, H. S., Heo, S. J., Kim, S. K., Han, J. W., Shin, K. H., Kim, S. H., Hur, H., Kim, K. S., Choi, Y. D., Kim, S., Lee, Y. H., Suh, J. S., Ahn, J. B., Chung, H. C., Noh, S. H., Rha, S. Y. & Kim, H. S., Feb 1 2019, In : Oncology (Switzerland). 96, 2, p. 59-69 11 p.

Research output: Contribution to journalArticle

docetaxel
gemcitabine
Sarcoma
Therapeutics
Synovial Sarcoma

Different effects of 4β-hydroxywithanolide E and withaferin A, two withanolides from Solanaceae plants, on the Akt signaling pathway in human breast cancer cells

Wang, H. C., Hu, H. H., Chang, F. R., Tsai, J. Y., Kuo, C. Y., Wu, Y-C. & Wu, C. C., Feb 1 2019, In : Phytomedicine. 53, p. 213-222 10 p.

Research output: Contribution to journalArticle

Withanolides
Solanaceae
Triple Negative Breast Neoplasms
Phosphatidylinositol 3-Kinases
Breast Neoplasms

Differential clinical significance of pre-, interim-, and post-treatment plasma Epstein–Barr virus DNA load in NK/T-cell lymphoma treated with P-GEMOX protocol

Wang, X. X., Li, P. F., Bai, B., Gao, Y., Rong, Q. X., Cai, Q. Q., Lin, S. X., Zhang, Y. J., Li, Z. M., Jiang, W. Q. & Huang, H-Q., Jan 1 2019, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

Natural Killer T-Cells
T-Cell Lymphoma
Human Herpesvirus 4
DNA
Survival

Differential expression of p120-catenin 1 and 3 isoforms in epithelial tissues

Venhuizen, J. H., Sommer, S., Span, P. N., Friedl, P. & Zegers, M. M., Dec 1 2019, In : Scientific reports. 9, 1, 90.

Research output: Contribution to journalArticle

Protein Isoforms
Epithelium
Intercellular Junctions
Epithelial Cells
Hair Follicle

Differential sensitivity analysis for resistant malignancies (DISARM) identifies common candidate therapies across platinum-resistant cancers

Gay, C. M., Tong, P., Cardnell, R. J., Sen, T., Su, X., Ma, J., Bara, R. O., Johnson, F. M., Wakefield, C., Heymach, J. V., Wang, J. & Byers, L. A., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 346-357 12 p.

Research output: Contribution to journalArticle

Platinum
Small Cell Lung Carcinoma
Neoplasms
Pharmaceutical Preparations
Aurora Kinase A

Diffusion-weighted imaging of the dentate nucleus after repeated application of gadolinium-based contrast agents in multiple sclerosis

Eisele, P., Szabo, K., Ebert, A., Radbruch, A., Platten, M., Schoenberg, S. O. & Gass, A., May 1 2019, In : Magnetic Resonance Imaging. 58, p. 1-5 5 p.

Research output: Contribution to journalArticle

Cerebellar Nuclei
Gadolinium
Contrast Media
Multiple Sclerosis
Imaging techniques

Diffusion-weighted MR imaging increases diagnostic accuracy of breast MR imaging for predicting axillary metastases in breast cancer patients

Guvenc, I., Whitman, G. J., Liu, P., Yalniz, C., Ma, J. & Dogan, B. E., Jan 1 2019, In : Breast Journal. 25, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

Diagnostic Imaging
Breast
Breast Neoplasms
Neoplasm Metastasis
Lymph Nodes

Digital artery deformation on movement of the proximal interphalangeal joint

Saito, S., Bise, R., Yoshikawa, A., Sekiguchi, H., Tsuge, I. & Toi, M., Feb 1 2019, In : Journal of Hand Surgery: European Volume. 44, 2, p. 187-195 9 p.

Research output: Contribution to journalArticle

Arteries
Joints
Radial Artery
Fingers
Rehabilitation

Diprophylline inhibits non-small cell lung cancer A549 cell proliferation and migration, and promotes apoptosis, by downregulating PI3K signaling pathway

Zhao, H. Y., Ren, Y. H., Ren, X. & Wang, Y., Jan 1 2019, In : Oncology Letters. 17, 1, p. 857-862 6 p.

Research output: Contribution to journalArticle

Dyphylline
1-Phosphatidylinositol 4-Kinase
Non-Small Cell Lung Carcinoma
Cell Movement
Down-Regulation

Disease-Free and Overall Survival among Patients with Operable HER2-Positive Breast Cancer Treated with Sequential vs Concurrent Chemotherapy: The ACOSOG Z1041 (Alliance) Randomized Clinical Trial

Buzdar, A. U., Suman, V. J., Meric-Bernstam, F., Leitch, A. M., Ellis, M. J., Boughey, J. C., Unzeitig, G. W., Royce, M. E. & Hunt, K. K., Jan 1 2019, In : JAMA Oncology. 5, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Arm
Randomized Controlled Trials
Breast Neoplasms
Drug Therapy

Disparities in gynecologic cancer genetics evaluation

Hinchcliff, E. M., Bednar, E. M., Lu, K. H. & Rauh-Hain, J. A., Jan 1 2019, (Accepted/In press) In : Gynecologic oncology.

Research output: Contribution to journalArticle

Carcinoid Tumor
Rectal Neoplasms
Prostate
Adenocarcinoma
Lymph Nodes

Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast

Müller, M., Samel-Pommerencke, A., Legrand, C., Tuorto, F., Lyko, F. & Ehrenhofer-Murray, A. E., Jan 1 2019, In : RNA biology.

Research output: Contribution to journalArticle

DNA damage response of clinical carbon ion versus photon radiation in human glioblastoma cells

Lopez Perez, R., Nicolay, N. H., Wolf, J. C., Frister, M., Schmezer, P., Weber, K. J. & Huber, P., Apr 1 2019, In : Radiotherapy and Oncology. 133, p. 77-86 10 p.

Research output: Contribution to journalArticle

Glioblastoma
Photons
DNA Damage
Carbon
Ions
3 Citations

DNA methylation profiles in African American prostate cancer patients in relation to disease progression

Rubicz, R., Zhao, S., Geybels, M., Wright, J. L., Kolb, S., Klotzle, B., Bibikova, M., Troyer, D., Lance, R., Ostrander, E. A., Feng, Z., Fan, J. B. & Stanford, J. L., Jan 1 2019, In : Genomics. 111, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

DNA Methylation
African Americans
Disease Progression
Prostatic Neoplasms
Recurrence

DNA Sequencing of Small Bowel Adenocarcinomas Identifies Targetable Recurrent Mutations in the ERBB2 Signaling Pathway

Adam, L., San Lucas, F. A., Fowler, R., Yu, Y., Wu, W., Liu, Y., Wang, H., Menter, D. G., Tetzlaff, M., Ensor, J., Manyam, G., Arold, S. T., Huff, C., Kopetz, E. S., Scheet, P. A. & Overman, M. J., Jan 15 2019, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 25, 2, p. 641-651 11 p.

Research output: Contribution to journalArticle

DNA Sequence Analysis
Adenocarcinoma
Exome
Mutation
Protein Array Analysis

Dnmt1 links BCR-ABLp210 to epigenetic tumor stem cell priming in myeloid leukemia

Vicente-Dueñas, C., González-Herrero, I., Sehgal, L., García-Ramírez, I., Rodríguez-Hernández, G., Pintado, B., Blanco, O., Criado, F. J. G., Cenador, M. B. G., Green, M. & Sánchez-García, I., Jan 1 2019, In : Leukemia. 33, 1, p. 249-278 30 p.

Research output: Contribution to journalArticle

Myeloid Leukemia
Neoplastic Stem Cells
Epigenomics
1 Citations

DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells

Veland, N., Lu, Y., Hardikar, S., Gaddis, S., Zeng, Y., Liu, B., Estecio, M. R., Takata, Y., Lin, K., Tomida, M. W., Shen, J., Saha, D., Gowher, H., Zhao, H. & Chen, T., Jan 10 2019, In : Nucleic acids research. 47, 1, p. 152-167 16 p.

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Methyltransferases
Mouse Embryonic Stem Cells
Germ Cells

Does group size matter? Captive chimpanzee (Pan troglodytes) behavior as a function of group size and composition

Neal Webb, S. J., Hau, J. & Schapiro, S. J., Jan 1 2019, In : American Journal of Primatology. 81, 1, e22947.

Research output: Contribution to journalArticle

group size
Pan troglodytes
locomotion
zoo
animal

Do Internal Mammary Nodes Matter?

Caudle, A. S. & Smith, B., Jan 1 2019, (Accepted/In press) In : Annals of surgical oncology.

Research output: Contribution to journalArticle

Breast

Dose escalation by intensity modulated radiotherapy in liver-directed concurrent chemoradiotherapy for locally advanced BCLC stage C hepatocellular carcinoma

Byun, H. K., Kim, H. J., Im, Y. R., Kim, D. Y., Han, K. H. & Seong, J., Apr 1 2019, In : Radiotherapy and Oncology. 133, p. 1-8 8 p.

Research output: Contribution to journalArticle

Intensity-Modulated Radiotherapy
Chemoradiotherapy
Hepatocellular Carcinoma
Survival
Liver

Dramatic response of nivolumab-associated psoriasiform dermatitis to etoposide

Rios, A., Cen, P., Dihn, B., Mays, S. R. & Patel, A., Jan 1 2019, In : European Journal of Cancer. 107, p. 97-99 3 p.

Research output: Contribution to journalLetter

Dermatitis
Etoposide
nivolumab

Dual-contrast pCASL using simultaneous gradient-echo/spin-echo multiband EPI

Zhang, K., Sturm, V. J., Buschle, L. R., Hahn, A., Yun, S. D., Jon Shah, N., Bendszus, M., Heiland, S., Schlemmer, H-P., Ziener, C. H. & Kurz, F. T., Apr 1 2019, In : Magnetic Resonance Imaging. 57, p. 359-367 9 p.

Research output: Contribution to journalArticle

Artifacts
Labeling
Magnetic Fields
Fingers
Cerebrovascular Circulation

Early Changes in Cardiovascular Biomarkers with Contemporary Thoracic Radiation Therapy for Breast Cancer, Lung Cancer, and Lymphoma

Demissei, B. G., Freedman, G., Feigenberg, S. J., Plastaras, J. P., Maity, A., Smith, A. M., McDonald, C., Sheline, K., Simone, C. B., Lin, L. L., Carver, J. R., Liu, P., Zhang, L., Bekelman, J. E. & Ky, B., Jan 1 2019, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

biomarkers
breast
lungs
radiation therapy
Lymphoma

Ectopic intracranial retinoblastoma in a 3.5-month-old infant without eye involvement and without evidence of heritability

Römer, T., Temming, P., Lohmann, D. R., Sturm, D., von Deimling, A., Sellhaus, B., Mull, M., Kontny, U. & Moser, O., Jan 1 2019, (Accepted/In press) In : Pediatric Blood and Cancer. e27599.

Research output: Contribution to journalArticle

Retinoblastoma
Neoplasms
Germ-Line Mutation
Stem Cell Transplantation
Gene Silencing

Editorial

Heuser, I. & Dantzer, R., Feb 1 2019, In : Psychoneuroendocrinology. 100, p. iii

Research output: Contribution to journalEditorial

Editorial: Basic research in bladder cancer – refining the tools. 3rd IBCN seminars series1

Black, P. C., Goebell, P. J., Kamat, A., Nawroth, R., Seiler, R., Williams, S. B. & Schmitz-Dräger, B. J., Jan 1 2019, (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Organoids
Research
Manuscripts
Neoplasms

EDITORIAL COMMENT

Cata, J. P., Jan 1 2019, In : Urology. 123, 1 p.

Research output: Contribution to journalComment/debate

Neoplasms
Therapeutics
Cardiotoxicity

Effect of health disparities on overall survival of patients with glioblastoma

Mandel, J. J., Youssef, M., Nam, J., Patel, A. J., Jalali, A., Ludmir, E. B., Liu, D., Wu, J., Armstrong, G., Huse, J., Bondy, M. & de Groot, J. F., Jan 1 2019, (Accepted/In press) In : Journal of neuro-oncology.

Research output: Contribution to journalArticle

Glioblastoma
Survival
Health
Standard of Care
County Hospitals

Effect of induction chemotherapy on swallowing in head and neck cancer patients

Portas, J., Corrêa, D., Queija, D., Arantes, L. M. R. B., Viana, L. D. S. & Carvalho, A. L., Jan 1 2019, In : Asian Pacific Journal of Cancer Prevention. 20, 1, p. 91-96 6 p.

Research output: Contribution to journalArticle

Induction Chemotherapy
Deglutition
Head and Neck Neoplasms
Quality of Life
Deglutition Disorders

Effect of inotuzumab ozogamicin on the QT interval in patients with haematologic malignancies using QTc-concentration modelling

Hibma, J. E., Kantarjian, H. M., DeAngelo, D. J. & Boni, J. P., Jan 1 2019, (Accepted/In press) In : British journal of clinical pharmacology.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Non-Hodgkin's Lymphoma
Electrocardiography
B-Lymphocytes

Effect of pregabalin on radiotherapy-related neuropathic pain in patients with head and neck cancer: A randomized controlled trial

Jiang, J., Li, Y., Shen, Q., Rong, X., Huang, X., Li, H., Zhou, L., Mai, H-Q., Zheng, D., Chen, M. Y., Xu, Y., Li, J., Hui, X., Simone, C. B., Gaertner, J., Argyriou, A. A., Chow, E., Chen, P. & Tang, Y., Jan 10 2019, In : Journal of Clinical Oncology. 37, 2, p. 135-143 9 p.

Research output: Contribution to journalArticle

Neuralgia
Head and Neck Neoplasms
Radiotherapy
Randomized Controlled Trials
Placebos

Effect of prior cancer on trial eligibility and treatment outcomes in nasopharyngeal carcinoma: Implications for clinical trial accrual

Wang, Y. Q., Lv, J. W., Tang, L. L., Du, X. J., Chen, L., Li, W. F., Liu, X., Guo, Y., Lin, A. H., Mao, Y. P., Sun, Y., Chen, Y. P. & Ma, J., Mar 1 2019, In : Oral Oncology. 90, p. 23-29 7 p.

Research output: Contribution to journalArticle

Effect of wu chu yu tang on gastroesophageal reflux disease: Randomized, double-blind, placebo-controlled trial

Shih, Y. S., Tsai, C. H., Li, T-C., Yu, C. J., Chou, J-W., Feng, C. L., Wang, K. T., Lai, H-C. & Hsieh, C-L., Mar 15 2019, In : Phytomedicine. 56, p. 118-125 8 p.

Research output: Contribution to journalArticle

Gastroesophageal Reflux
Placebos
Omeprazole
Control Groups
Proton Pump Inhibitors

Effects of adjuvant chemotherapy in T1N0M0 triple-negative breast cancer

Ren, Y. X., Hao, S., Jin, X., Ye, F. G., Gong, Y., Jiang, Y. Z. & Shao, Z., Feb 1 2019, In : Breast. 43, p. 97-104 8 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Adjuvant Chemotherapy
Recurrence
Survival
Anthracyclines

Effects of Chinese herbal medicine therapy on survival and hepatic outcomes in patients with hepatitis C virus infection in Taiwan

Tsai, F-J., Cheng, C. F., Chen, C. J., Lin, C. Y., Wu, Y. F., Li, T. M., Chuang, P-H., Wu, Y-C., Lai, C. H., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, J. C., Lin, C. C., Liang, W. M. & Lin, Y. J., Apr 1 2019, In : Phytomedicine. 57, p. 30-38 9 p.

Research output: Contribution to journalArticle

Phytotherapy
Herbal Medicine
Virus Diseases
Taiwan
Hepacivirus

Efficacy and safety of the combination of metformin, everolimus and exemestane in overweight and obese postmenopausal patients with metastatic, hormone receptor-positive, HER2-negative breast cancer: a phase II study

Yam, C., Esteva, F. J., Patel, M. M., Raghavendra, A. S., Ueno, N. T., Moulder, S., Hess, K. R., Shroff, G., Hodge, S., Koenig, K. B., Chavez Mac Gregor, M., Griner, R. L., Yeung, S. C. J., Hortobagyi, G. N. & Valero, V., Jan 1 2019, (Accepted/In press) In : Investigational New Drugs.

Research output: Contribution to journalArticle

exemestane
Metformin
Hormones
Breast Neoplasms
Safety

Efficacy and safety of the dual SYK/JAK inhibitor cerdulatinib in patients with relapsed or refractory B-cell malignancies: Results of a phase I study

Hamlin, P. A., Flinn, I. W., Wagner-Johnston, N., Burger, J. A., Coffey, G. P., Conley, P. B., Michelson, G., Leeds, J. M., Der, K., Kim, Y., Sabalvaro-Torres, A., Birrell, M., Pandey, A., Curnutte, J. T. & Patel, M. R., Jan 1 2019, (Accepted/In press) In : American journal of hematology.

Research output: Contribution to journalArticle

B-Lymphocytes
Safety
Neoplasms
4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide

Efficacy of cryoablation combined with sorafenib for the treatment of advanced renal cell carcinoma

Liu, C., Cao, F., Xing, W., Si, T., Yu, H., Yang, X. & Guo, Z., Jan 1 2019, (Accepted/In press) In : International Journal of Hyperthermia.

Research output: Contribution to journalArticle

Cryosurgery
Renal Cell Carcinoma
Disease-Free Survival
Drug-Related Side Effects and Adverse Reactions
Therapeutics

Efficacy of Mobile Phone-Delivered Smoking Cessation Interventions for Socioeconomically Disadvantaged Individuals: A Randomized Clinical Trial

Vidrine, D. J., Frank-Pearce, S. G., Vidrine, J. I., Tahay, P. D., Marani, S. K., Chen, S., Yuan, Y., Cantor, S. B. & Prokhorov, A. V., Feb 1 2019, In : JAMA Internal Medicine. 179, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

Cell Phones
Vulnerable Populations
Smoking Cessation
Nicotine
Randomized Controlled Trials

EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression

Liu, L., Yang, Y., Liu, S., Tao, T., Cai, J., Wu, J., Guan, H., Zhu, X., He, Z., Li, J., Song, E., Zeng, M-S. & Li, M., Jan 31 2019, In : Oncogene. 38, 5, p. 747-764 18 p.

Research output: Contribution to journalArticle

beta Catenin
Epidermal Growth Factor
Non-Small Cell Lung Carcinoma
Neoplasms
Proteins

EGFR amplification and classical subtype are associated with a poor response to bevacizumab in recurrent glioblastoma

Hovinga, K. E., McCrea, H. J., Brennan, C., Huse, J., Zheng, J., Esquenazi, Y., Panageas, K. S. & Tabar, V., Jan 1 2019, (Accepted/In press) In : Journal of neuro-oncology.

Research output: Contribution to journalArticle

EGFR mono-antibody salvage therapy for locally advanced and distant metastatic penile cancer: Clinical outcomes and genetic analysis

Huang, K. B., Liu, R-Y., Peng, Q. H., Li, Z. S., Jiang, L. J., Guo, S. J., Zhou, Q. H., Liu, T. Y., Deng, C. Z., Yao, K., Qin, Z. K., Liu, Z. W., Li, Y. H., Han, H. & Zhou, F-J., Jan 1 2019, In : Urologic Oncology: Seminars and Original Investigations. 37, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Penile Neoplasms
Salvage Therapy
Epidermal Growth Factor Receptor
Squamous Cell Carcinoma
Antibodies

EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC

Zhang, R., Lai, L., He, J., Chen, C., You, D., Duan, W., Dong, X., Zhu, Y., Lin, L., Shen, S., Guo, Y., Su, L., Shafer, A., Moran, S., Fleischer, T., Bjaanæs, M. M., Karlsson, A., Planck, M., Staaf, J., Helland, Å. & 4 othersEsteller, M., Wei, Y., Chen, F. & Christiani, D. C., Jan 1 2019, In : Epigenetics.

Research output: Contribution to journalArticle

Skin Neoplasms
CTLA-4 Antigen
Cell Death
Epidermal Growth Factor Receptor
Therapeutics
Marginal Zone B-Cell Lymphoma
Breast
Salvage Therapy
Radiotherapy
Therapeutics