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2019

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. & 1 others, Weinshilboum, R. M., Jul 2019, In : Clinical pharmacology and therapeutics. 106, 1, p. 219-227 9 p.

Research output: Contribution to journalArticle

Open Access
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms
4 Citations (Scopus)

Disease-Free and Overall Survival among Patients with Operable HER2-Positive Breast Cancer Treated with Sequential vs Concurrent Chemotherapy: The ACOSOG Z1041 (Alliance) Randomized Clinical Trial

Buzdar, A. U., Suman, V. J., Meric-Bernstam, F., Leitch, A. M., Ellis, M. J., Boughey, J. C., Unzeitig, G. W., Royce, M. E. & Hunt, K. K., Jan 2019, In : JAMA Oncology. 5, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Arm
Randomized Controlled Trials
Breast Neoplasms
Drug Therapy
2018
4 Citations (Scopus)

A phase II study of tipifarnib and gemcitabine in metastatic breast cancer

Yam, C., Murthy, R. K., Valero, V., Szklaruk, J., Shroff, G. S., Stalzer, C. J., Buzdar, A. U., Murray, J. L., Yang, W., Hortobagyi, G. N., Moulder, S. L. & Arun, B., Apr 1 2018, In : Investigational New Drugs. 36, 2, p. 299-306 8 p.

Research output: Contribution to journalArticle

gemcitabine
tipifarnib
Breast Neoplasms
Confidence Intervals
Farnesyltranstransferase
2017
9 Citations (Scopus)
Clinical Trials
Neoplasms
Health Care Costs
Biomedical Research
Industry
17 Citations (Scopus)

Genomic characterization of HER2-positive breast cancer and response to neoadjuvant trastuzumab and chemotherapy-results from the ACOSOG Z1041 (Alliance) trial

Lesurf, R., Griffith, O. L., Griffith, M., Hundal, J., Trani, L., Watson, M. A., Aft, R., Ellis, M. J., Ota, D., Suman, V. J., Meric-Bernstam, F., Leitch, A. M., Boughey, J. C., Unzeitig, G., Buzdar, A. U., Hunt, K. K. & Mardis, E. R., May 1 2017, In : Annals of oncology : official journal of the European Society for Medical Oncology. 28, 5, p. 1070-1077 8 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Drug Therapy
RNA
erbB-2 Genes
Exome
101 Citations (Scopus)

Long-term prognostic risk after neoadjuvant chemotherapy associated with residual cancer burden and breast cancer subtype

Symmans, W. F., Wei, C., Gould, R., Yu, X., Zhang, Y., Liu, M., Walls, A., Bousamra, A., Ramineni, M., Sinn, B., Hunt, K., Buchholz, T. A., Valero, V., Buzdar, A. U., Yang, W., Brewster, A. M., Moulder, S., Pusztai, L., Hatzis, C. & Hortobagyi, G. N., Apr 1 2017, In : Journal of Clinical Oncology. 35, 10, p. 1049-1060 12 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Breast Neoplasms
Drug Therapy
Hormones
Paclitaxel
2 Citations (Scopus)
Clinical Trials
Research
Neoplasms
Industry
Therapeutics
5 Citations (Scopus)

Risk of acute myeloid leukemia and myelodysplastic syndrome among older women receiving anthracycline-based adjuvant chemotherapy for breast cancer on Modern Cooperative Group Trials (Alliance A151511)

Freedman, R. A., Seisler, D. K., Foster, J. C., Sloan, J. A., Lafky, J. M., Kimmick, G. G., Hurria, A., Cohen, H. J., Winer, E. P., Hudis, C. A., Partridge, A. H., Carey, L. A., Jatoi, A., Klepin, H. D., Citron, M., Berry, D. A., Shulman, L. N., Buzdar, A. U., Suman, V. J. & Muss, H. B., Jan 1 2017, In : Breast Cancer Research and Treatment. 161, 2, p. 363-373 11 p.

Research output: Contribution to journalArticle

Anthracyclines
Myelodysplastic Syndromes
Adjuvant Chemotherapy
Acute Myeloid Leukemia
Breast Neoplasms
7 Citations (Scopus)

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway

Dudenkov, T. M., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Ibrahim-zada, I., Batzler, A., Jenkins, G. D., Pietrzak, T. L., Carlson, E. E., Barman, P., Goetz, M. P., Northfelt, D. W., Moreno-Aspita, A., Williard, C. V., Kalari, K. R., Nakamura, Y., Wang, L. & Weinshilboum, R. M., Jul 1 2017, In : Breast Cancer Research and Treatment. 164, 1, p. 189-199 11 p.

Research output: Contribution to journalArticle

Estrone
Genome-Wide Association Study
Androstenedione
Single Nucleotide Polymorphism
Steryl-Sulfatase
2016
3 Citations (Scopus)

Identification of early breast cancer patient cohorts who may benefit from lapatinib therapy

Strasser-Weippl, K., Horick, N., Smith, I. E., O'Shaughnessy, J., Ejlertsen, B., Boyle, F., Buzdar, A. U., Fumoleau, P., Gradishar, W., Martin, M., Moy, B., Piccart-Gebhart, M., Pritchard, K. I., Lindquist, D., Rappold, E., Finkelstein, D. M. & Goss, P. E., Mar 1 2016, In : European Journal of Cancer. 56, p. 85-92 8 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Numbers Needed To Treat
Therapeutics
Hormones
Protein-Tyrosine Kinases
16 Citations (Scopus)

Impact of race, ethnicity, and BMI on achievement of pathologic complete response following neoadjuvant chemotherapy for breast cancer: a pooled analysis of four prospective Alliance clinical trials (A151426)

Warner, E. T., Ballman, K. V., Strand, C., Boughey, J. C., Buzdar, A. U., Carey, L. A., Sikov, W. M. & Partridge, A. H., Aug 1 2016, In : Breast Cancer Research and Treatment. 159, 1, p. 109-118 10 p.

Research output: Contribution to journalArticle

Body Mass Index
Clinical Trials
Breast Neoplasms
Drug Therapy
Neoadjuvant Therapy
2015
428 Citations (Scopus)

Aromatase inhibitors versus tamoxifen in early breast cancer: Patient-level meta-analysis of the randomised trials

Early Breast Cancer Trialists’ Collaborative Group, Oct 3 2015, In : The Lancet. 386, 10001, p. 1341-1352 12 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
Tamoxifen
Meta-Analysis
Breast Neoplasms
Mortality
19 Citations (Scopus)

Estrogen receptor expression in 21-Gene recurrence score predicts increased late recurrence for estrogen-positive/HER2-Negative breast cancer

Dowsett, M., Sestak, I., Buus, R., Lopez-Knowles, E., Mallon, E., Howell, A., Forbes, J. F., Buzdar, A. U. & Cuzick, J., Jun 15 2015, In : Clinical Cancer Research. 21, 12, p. 2763-2770 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Breast Neoplasms
Recurrence
Gene Regulatory Networks
22 Citations (Scopus)

Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole

Ingle, J. N., Kalari, K. R., Buzdar, A. U., Robson, M. E., Goetz, M. P., Desta, Z., Barman, P., Dudenkov, T. T., Northfelt, D. W., Perez, E. A., Flockhart, D. A., Williard, C. V., Wang, L. & Weinshilboum, R. M., May 26 2015, In : Steroids. 99, Part A, p. 32-38 7 p.

Research output: Contribution to journalArticle

Estrogens
Breast Neoplasms
Estrone
Metabolites
Hormones
6 Citations (Scopus)

Health related quality of life of women in TEACH, a randomised placebo controlled adjuvant trial of lapatinib in early stage Human Epidermal Growth Factor Receptor (HER2) overexpressing breast cancer

Boyle, F. M., Smith, I. E., O'Shaughnessy, J., Ejlertsen, B., Buzdar, A. U., Fumoleau, P., Gradishar, W., Martin, M., Moy, B., Piccart-Gebhart, M., Pritchard, K. I., Lindquist, D., Amonkar, M., Huang, Y., Rappold, E., Williams, L. S., Wang-Silvanto, J., Kaneko, T., Finkelstein, D. M. & Goss, P. E., Apr 2015, In : European Journal of Cancer. 51, 6, p. 685-696 12 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Placebos
Quality of Life
Breast Neoplasms
lapatinib
15 Citations (Scopus)

Long-term hazard of recurrence in HER2+ breast cancer patients untreated with anti-HER2 therapy

Strasser-Weippl, K., Horick, N., Smith, I. E., O'Shaughnessy, J., Ejlertsen, B., Boyle, F., Buzdar, A. U., Fumoleau, P., Gradishar, W., Martin, M., Moy, B., Piccart-Gebhart, M., Pritchard, K. I., Lindquist, D., Rappold, E., Finkelstein, D. M. & Goss, P. E., Apr 16 2015, In : Breast Cancer Research. 17, 1, 56.

Research output: Contribution to journalArticle

Breast Neoplasms
Recurrence
Therapeutics
Hormones
Disease-Free Survival
75 Citations (Scopus)

Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration

Breast International Group-North American Breast Cancer Group (BIG-NABCG) collaboration, Jul 1 2015, In : Annals of Oncology. 26, 7, p. 1280-1291 12 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Clinical Trials
Breast Neoplasms
Interdisciplinary Communication
Residual Neoplasm
2014
73 Citations (Scopus)

Locoregional recurrence risk for patients with T1,2 breast cancer with 1-3 positive lymph nodes treated with mastectomy and systemic treatment

McBride, A., Allen, P., Woodward, W., Kim, M., Kuerer, H. M., Drinka, E. K., Sahin, A., Strom, E. A., Buzdar, A., Valero, V., Hortobagyi, G. N., Hunt, K. K. & Buchholz, T. A., Jun 1 2014, In : International Journal of Radiation Oncology Biology Physics. 89, 2, p. 392-398 7 p.

Research output: Contribution to journalArticle

lymphatic system
Mastectomy
breast
radiation therapy
Radiotherapy
58 Citations (Scopus)

Which threshold for ER positivity? a retrospective study based on 9639 patients

Yi, M., Huo, L., Koenig, K. B., Mittendorf, E. A., Meric-Bernstam, F., Kuerer, H. M., Bedrosian, I., Buzdar, A. U., Symmans, W. F., Crow, J. R., Bender, M., Shah, R. R., Hortobagyi, G. N. & Hunt, K. K., May 1 2014, In : Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 25, 5, p. 1004-1011 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Retrospective Studies
Estrogen Receptor alpha
Neoplasms
Staining and Labeling
2013
96 Citations (Scopus)

Adjuvant lapatinib for women with early-stage HER2-positive breast cancer: A randomised, controlled, phase 3 trial

Goss, P. E., Smith, I. E., O'Shaughnessy, J., Ejlertsen, B., Kaufmann, M., Boyle, F., Buzdar, A. U., Fumoleau, P., Gradishar, W., Martin, M., Moy, B., Piccart-Gebhart, M., Pritchard, K. I., Lindquist, D., Chavarri-Guerra, Y., Aktan, G., Rappold, E., Williams, L. S. & Finkelstein, D. M., Jan 1 2013, In : The lancet oncology. 14, 1, p. 88-96 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Placebos
Disease-Free Survival
lapatinib
Adjuvant Chemotherapy

Breast cancer

Buzdar, A. U., Buchholz, T. A., Taylor, S. H., Hortobagyi, G. N. & Hunt, K. K., Aug 1 2013, 60 Years of Survival Outcomes at the University of Texas MD Anderson Cancer Center. Springer New York, Vol. 9781461451976. p. 19-34 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Breast Neoplasms
Radical Mastectomy
Therapeutics
Breast
Radiation
1 Citation (Scopus)

Combination endocrine treatments unproven in breast cancer

Buzdar, A. U., Sep 1 2013, In : The lancet oncology. 14, 10, p. 917-918 2 p.

Research output: Contribution to journalLetter

Androstadienes
Estrogen Antagonists
Nitriles
Aromatase Inhibitors
Triazoles

Commentary

Buzdar, A. U., 2013, In : Annals of Internal Medicine. 159, 6

Research output: Contribution to journalComment/debate

110 Citations (Scopus)
Epirubicin
Neoadjuvant Therapy
Paclitaxel
Fluorouracil
Cyclophosphamide
12 Citations (Scopus)

Immunohistochemical BAG1 expression improves the estimation of residual risk by IHC4 in postmenopausal patients treated with anastrazole or tamoxifen: A TransATAC study

Afentakis, M., Dowsett, M., Sestak, I., Salter, J., Howell, T., Buzdar, A., Forbes, J. & Cuzick, J., Jul 2013, In : Breast Cancer Research and Treatment. 140, 2, p. 253-262 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Recurrence
Apoptosis Regulatory Proteins
Estrogen Receptors
Chromosomes
18 Citations (Scopus)

Mammographic breast density response to aromatase inhibition

Vachon, C. M., Suman, V. J., Brandt, K. R., Kosel, M. L., Buzdar, A. U., Olson, J. E., Wu, F. F., Flickinger, L. M., Ursin, G., Elliott, C. R., Shepherd, L., Weinshilboum, R. M., Goss, P. E. & Ingle, J. N., Apr 15 2013, In : Clinical Cancer Research. 19, 8, p. 2144-2153 10 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
Aromatase
Therapeutics
Breast Density
Hormones
46 Citations (Scopus)

Pathologic complete response to neoadjuvant chemotherapy with trastuzumab predicts for improved survival in women with HER2-overexpressing breast cancer

Kim, M. M., Allen, P., Gonzalez-Angulo, A. M., Woodward, W. A., Meric-Bernstam, F., Buzdar, A. U., Hunt, K. K., Kuerer, H. M., Litton, J. K., Hortobagyi, G. N., Buchholz, T. A. & Mittendorf, E. A., Aug 1 2013, In : Annals of Oncology. 24, 8, p. 1999-2004 6 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Drug Therapy
Survival
Recurrence
Confidence Intervals
2 Citations (Scopus)

Tamoxifen therapy for patients with breast cancer

Litton, J., Buzdar, A. U., Chavez Mac Gregor, M., Gonzalez-Angulo, A. & Hortobagyi, G., 2013, In : The Lancet. 381, 9883, p. 2077-2078 2 p.

Research output: Contribution to journalLetter

Hormonal Antineoplastic Agents
Premenopause
Postmenopause
Nitriles
Aromatase Inhibitors
31 Citations (Scopus)

TSPYl5 SNPs: Association with plasma estradiol concentrations and aromatase expression

Liu, M., Ingle, J. N., Fridley, B. L., Buzdar, A. U., Robson, M. E., Kubo, M., Wang, L., Batzler, A., Jenkins, G. D., Pietrzak, T. L., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Perez, E. A., Williard, C. V., Schaid, D. J., Nakamura, Y. & Weinshilboum, R. M., Apr 1 2013, In : Molecular Endocrinology. 27, 4, p. 657-670 14 p.

Research output: Contribution to journalArticle

Aromatase
Single Nucleotide Polymorphism
Estradiol
Estrogen Receptors
Genotype
11 Citations (Scopus)

Using multiple targeted therapies in oncology: Considerations for use, and progress to date in breast cancer

Kelly, C. M. & Buzdar, A. U., May 1 2013, In : Drugs. 73, 6, p. 505-515 11 p.

Research output: Contribution to journalArticle

Breast Neoplasms
letrozole
Epidermal Growth Factor
Clinical Trials
Triple Negative Breast Neoplasms
2012
1 Citation (Scopus)

Aromatase inhibitors in premenopausal breast cancer

Kelly, C. M. & Buzdar, A. U., Apr 1 2012, In : The lancet oncology. 13, 4, p. 320-321 2 p.

Research output: Contribution to journalLetter

Antineoplastic Combined Chemotherapy Protocols
Goserelin
Nitriles
Aromatase Inhibitors
Neoadjuvant Therapy
34 Citations (Scopus)

Efficacy of neoadjuvant therapy with trastuzumab concurrent with anthracycline- and nonanthracycline-based regimens for HER2-positive breast cancer

Bayraktar, S., Gonzalez-Angulo, A. M., Lei, X., Buzdar, A. U., Valero, V., Melhem-Bertrandt, A., Kuerer, H. M., Hortobagyi, G. N., Sahin, A. A. & Meric-Bernstam, F., May 1 2012, In : Cancer. 118, 9, p. 2385-2393 9 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Anthracyclines
Breast Neoplasms
Recurrence
Survival
38 Citations (Scopus)

Ensuring quality cancer care: A follow-up review of the Institute of Medicine's 10 recommendations for improving the quality of cancer care in America

Spinks, T., Albright, H. W., Feeley, T. W., Walters, R. S., Burke, T. W., Aloia, T. A., Bruera, E., Buzdar, A. U., Foxhall, L. E., Hui, D., Summers, B., Rodriguez, M. A., Dubois, R. & Shine, K. I., May 15 2012, In : Cancer. 118, 10, p. 2571-2582 12 p.

Research output: Contribution to journalReview article

National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
Quality of Health Care
Neoplasms
State Medicine
Delivery of Health Care
13 Citations (Scopus)

Making genuine progress against metastatic breast cancer

Lyman, G. H., Burstein, H. J., Buzdar, A. U., D'Agostino, R. & Ellis, P. A., Oct 1 2012, In : Journal of Clinical Oncology. 30, 28, p. 3448-3451 4 p.

Research output: Contribution to journalComment/debate

Drug Approval
Quality of Life
Breast Neoplasms
Safety
27 Citations (Scopus)

Phase III trial evaluating weekly paclitaxel versus docetaxel in combination with capecitabine in operable breast cancer

Kelly, C. M., Green, M. C., Broglio, K., Thomas, E. S., Brewster, A. M., Valero, V., Ibrahim, N. K., Gonzalez-Angulo, A. M., Booser, D. J., Walters, R. S., Hunt, K. K., Hortobagyi, G. N. & Buzdar, A. U., Mar 20 2012, In : Journal of Clinical Oncology. 30, 9, p. 930-935 6 p.

Research output: Contribution to journalArticle

docetaxel
Epirubicin
Paclitaxel
Fluorouracil
Cyclophosphamide
191 Citations (Scopus)

Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients

Jung, E. J., Santarpia, L., Kim, J., Esteva, F. J., Moretti, E., Buzdar, A. U., Di Leo, A., Le, X. F., Bast, R. C., Park, S. T., Pusztai, L. & Calin, G. A., May 15 2012, In : Cancer. 118, 10, p. 2603-2614 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Breast Neoplasms
Neoplasms
Drug Therapy
Trastuzumab
4 Citations (Scopus)

Randomized double-blind phase 2 trial of 3 doses of TAS-108 in patients with advanced or metastatic postmenopausal breast cancer

Buzdar, A., Vogel, C., Schwartzberg, L., Garin, A., Perez, A., Ingle, J., Houghton, M., Zergebel, C. & Kimball, B., Jul 1 2012, In : Cancer. 118, 13, p. 3244-3253 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Hormones
Trientine
Double-Blind Method
Hyperglycemia
13 Citations (Scopus)

Randomized phase II non-inferiority study (no16853) of two different doses of capecitabine in combination with docetaxel for locally advanced/metastatic breast cancer

Buzdar, A. U., Xu, B., Digumarti, R., Goedhals, L., Hu, X., Semiglazov, V., Cheporov, S., Gotovkin, E., Hoersch, S., Rittweger, K., Miles, D. W., O'shaughnessy, J. & Tjulandin, S., Mar 1 2012, In : Annals of Oncology. 23, 3, p. 589-597 9 p.

Research output: Contribution to journalArticle

docetaxel
Breast Neoplasms
Disease-Free Survival
Confidence Intervals
Anthracyclines

Screening for cardiac risk before anthracycline administration: What are the real benefits?

Ewer, M. S., Yang, M. & Buzdar, A. U., Feb 2012, In : Clinical breast cancer. 12, 1, p. 1-3 3 p.

Research output: Contribution to journalComment/debate

Anthracyclines
3 Citations (Scopus)

Short-term biomarker modulation prevention study of anastrozole in women at increased risk for second primary breast cancer

Arun, B., Valero, V., Liu, D., Brewster, A., Green, M., Gutierrez-Barrera, A., Akar, U., Rivera, E., Esteva, F. J., Buzdar, A. U., Hortobagyi, G. N. & Sneige, N., Feb 1 2012, In : Cancer Prevention Research. 5, 2, p. 276-282 7 p.

Research output: Contribution to journalArticle

Second Primary Neoplasms
Insulin-Like Growth Factor Binding Protein 1
Biomarkers
Breast Neoplasms
Breast
41 Citations (Scopus)

The sequential use of endocrine treatment for advanced breast cancer: Where are we?

Barrios, C., Forbes, J. F., Jonat, W., Conte, P., Gradishar, W., Buzdar, A., Gelmon, K., Gnant, M., Bonneterre, J., Toi, M., Hudis, C. & Robertson, J. F. R., Jun 6 2012, In : Annals of Oncology. 23, 6, p. 1378-1386 9 p.

Research output: Contribution to journalReview article

Breast Neoplasms
Therapeutics
Randomized Controlled Trials
Hormones
Aromatase Inhibitors
2011
3 Citations (Scopus)

10-year analysis of the ATAC trial: Wrong conclusion? - Authors' reply

Cuzick, J., Sestak, I., Baum, M., Buzdar, A., Howell, A., Dowsett, M. & Forbes, J. F., Mar 2011, In : The lancet oncology. 12, 3, 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Anti-angiogenic therapies in metastatic breast cancer-an unfulfilled dream

Buzdar, A. U., Apr 1 2011, In : The lancet oncology. 12, 4, p. 316-318 3 p.

Research output: Contribution to journalLetter

Antineoplastic Combined Chemotherapy Protocols
Indoles
Angiogenesis Inhibitors
Niacinamide
Paclitaxel
50 Citations (Scopus)

Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast

Kuerer, H. M., Buzdar, A. U., Mittendorf, E. A., Esteva, F. J., Lucci, A., Vence, L. M., Radvanyi, L., Meric-Bernstam, F., Hunt, K. K. & Symmans, W. F., Jan 1 2011, In : Cancer. 117, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Carcinoma, Intraductal, Noninfiltrating
Breast
Antibody-Dependent Cell Cytotoxicity
Natural Killer Cells
Trastuzumab
33 Citations (Scopus)
Segmental Mastectomy
Breast Neoplasms
Recurrence
Neoplasms
Therapeutics
49 Citations (Scopus)

Influence of comorbidities and age on risk of death without recurrence: A retrospective analysis of the arimidex, tamoxifen alone or in combination trial

Ring, A., Sestak, I., Baum, M., Howell, A., Buzdar, A., Dowsett, M., Forbes, J. F. & Cuzick, J., Nov 10 2011, In : Journal of Clinical Oncology. 29, 32, p. 4266-4272 7 p.

Research output: Contribution to journalArticle

Tamoxifen
Comorbidity
Recurrence
Odds Ratio
Breast Neoplasms
63 Citations (Scopus)

Novel staging system for predicting disease-specific survival in patients with breast cancer treated with surgery as the first intervention: Time to modify the current American Joint Committee on Cancer staging system

Yi, M., Mittendorf, E. A., Cormier, J. N., Buchholz, T. A., Bilimoria, K., Sahin, A. A., Hortobagyi, G. N., Gonzalez-Angulo, A. M., Luo, S., Buzdar, A. U., Crow, J. R., Kuerer, H. M. & Hunt, K. K., Dec 10 2011, In : Journal of Clinical Oncology. 29, 35, p. 4654-4661 8 p.

Research output: Contribution to journalArticle

Neoplasm Staging
Estrogen Receptors
Progesterone Receptors
Breast Neoplasms
Survival
14 Citations (Scopus)

Phase III randomized trial of dose intensive neoadjuvant chemotherapy with or without G-CSF in locally advanced breast cancer: Long-term results

Arun, B. K., Dhinghra, K., Valero, V., Kau, S. W., Broglio, K., Booser, D., Guerra, L., Yin, G., Walters, R., Sahin, A., Ibrahim, N., Buzdar, A. U., Frye, D., Sneige, N., Strom, E., Ross, M., Theriault, R. L., Vadhan-Raj, S. & Hortobagyi, G. N., Dec 2 2011, In : Oncologist. 16, 11, p. 1527-1534 8 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Doxorubicin
Fluorouracil
Cyclophosphamide
Breast Neoplasms
25 Citations (Scopus)

Predictive algorithms for adjuvant therapy: TransATAC

Dowsett, M., Salter, J., Zabaglo, L., Mallon, E., Howell, A., Buzdar, A. U., Forbes, J., Pineda, S. & Cuzick, J., Jul 1 2011, In : Steroids. 76, 8, p. 777-780 4 p.

Research output: Contribution to journalArticle

Biomarkers
Tamoxifen
Recurrence
Estrogen Receptors
Decision Making
436 Citations (Scopus)

Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the genomic health recurrence score in early breast cancer

Cuzick, J., Dowsett, M., Pineda, S., Wale, C., Salter, J., Quinn, E., Zabaglo, L., Mallon, E., Green, A. R., Ellis, I. O., Howell, A., Buzdar, A. U. & Forbes, J. F., Nov 10 2011, In : Journal of Clinical Oncology. 29, 32, p. 4273-4278 6 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Estrogen Receptors
Breast Neoplasms
Recurrence
Health