Find Research Outputs

Search concepts
Selected Filters
2019
2 Citations (Scopus)

Arid1a is essential for intestinal stem cells through Sox9 regulation

Hiramatsu, Y., Fukuda, A., Ogawa, S., Goto, N., Ikuta, K., Tsuda, M., Matsumoto, Y., Kimura, Y., Yoshioka, T., Takada, Y., Maruno, T., Hanyu, Y., Tsuruyama, T., Wang, Z., Akiyama, H., Takaishi, S., Miyoshi, H., Taketo, M. M., Chiba, T. & Seno, H., Jan 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1704-1713 10 p.

Research output: Contribution to journalArticle

Stem Cells
Homeostasis
Wnt Receptors
Epithelial Cells
Maintenance
1 Citation (Scopus)

Bmi1 marks gastric stem cells located in the isthmus in mice

Yoshioka, T., Fukuda, A., Araki, O., Ogawa, S., Hanyu, Y., Matsumoto, Y., Yamaga, Y., Nakanishi, Y., Kawada, K., Sakai, Y., Chiba, T. & Seno, H., Jun 2019, In : Journal of Pathology. 248, 2, p. 179-190 12 p.

Research output: Contribution to journalArticle

Stomach
Stem Cells
Tamoxifen
Organoids
Pyloric Antrum
2 Citations (Scopus)
Sclerosing Cholangitis
Pancreatitis
Autoantibodies
Autoimmune Diseases
Immunoglobulin G
13 Citations (Scopus)

Clinical practice guidelines for IgG4-related sclerosing cholangitis

Kamisawa, T., Nakazawa, T., Tazuma, S., Zen, Y., Tanaka, A., Ohara, H., Muraki, T., Inui, K., Inoue, D., Nishino, T., Naitoh, I., Itoi, T., Notohara, K., Kanno, A., Kubota, K., Hirano, K., Isayama, H., Shimizu, K., Tsuyuguchi, T., Shimosegawa, T. & 7 others, Kawa, S., Chiba, T., Okazaki, K., Takikawa, H., Kimura, W., Unno, M. & Yoshida, M., Jan 2019, In : Journal of Hepato-Biliary-Pancreatic Sciences. 26, 1, p. 9-42 34 p.

Research output: Contribution to journalReview article

Open Access
Sclerosing Cholangitis
Practice Guidelines
Immunoglobulin G
Guidelines
Cholangitis
2 Citations (Scopus)

Genetic analysis of a case of Helicobacter pylori-uninfected intramucosal gastric cancer in a family with hereditary diffuse gastric cancer

Funakoshi, T., Miyamoto, S., Kakiuchi, N., Nikaido, M., Setoyama, T., Yokoyama, A., Horimatsu, T., Yamada, A., Torishima, M., Kosugi, S., Yamada, H., Sugimura, H., Haga, H., Sakai, Y., Ogawa, S., Seno, H., Muto, M. & Chiba, T., Jul 12 2019, In : Gastric Cancer. 22, 4, p. 892-898 7 p.

Research output: Contribution to journalArticle

Signet Ring Cell Carcinoma
Helicobacter pylori
Stomach Neoplasms
Mutation
Germ-Line Mutation

Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis

Nishikawa, Y., Kodama, Y., Shiokawa, M., Matsumori, T., Marui, S., Kuriyama, K., Kuwada, T., Sogabe, Y., Kakiuchi, N., Tomono, T., Mima, A., Morita, T., Ueda, T., Tsuda, M., Yamauchi, Y., Sakuma, Y., Ota, Y., Maruno, T., Uza, N., Uesugi, M. & 3 others, Kageyama, R., Chiba, T. & Seno, H., May 30 2019, In : Oncogene. 38, 22, p. 4283-4296 14 p.

Research output: Contribution to journalArticle

Carcinogenesis
Acinar Cells
Metaplasia
Adenocarcinoma
Neoplasms
1 Citation (Scopus)

Impaired expression of innate immunity-related genes in IgG4-related disease: A possible mechanism in the pathogenesis of IgG4-RD

Nakamura, T., Satoh-Nakamura, T., Nakajima, A., Kawanami, T., Sakai, T., Fujita, Y., Iwao, H., Miki, M., Masaki, Y., Okazaki, T., Ishigaki, Y., Kawano, M., Yamada, K., Matsui, S., Saeki, T., Kamisawa, T., Yamamoto, M., Hamano, H., Origuchi, T., Hirata, S. & 8 others, Tanaka, Y., Tsuboi, H., Sumida, T., Okazaki, K., Tanaka, M., Chiba, T., Mimori, T. & Umehara, H., Jan 1 2019, (Accepted/In press) In : Modern Rheumatology.

Research output: Contribution to journalArticle

Innate Immunity
Immunoglobulin G
Genes
Secretory Leukocyte Peptidase Inhibitor
Steroids
2 Citations (Scopus)

Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells

Goto, N., Fukuda, A., Yamaga, Y., Yoshikawa, T., Maruno, T., Maekawa, H., Inamoto, S., Kawada, K., Sakai, Y., Miyoshi, H., Taketo, M. M., Chiba, T. & Seno, H., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 26, p. 12996-13005 10 p.

Research output: Contribution to journalArticle

Open Access
Neoplastic Stem Cells
Colorectal Neoplasms
Neoplasms
Interleukin-13
Cell Differentiation
2 Citations (Scopus)

Risk Factors for Pancreatic Stone Formation in Type 1 Autoimmune Pancreatitis: A Long-term Japanese Multicenter Analysis of 624 Patients

Ito, T., Kawa, S., Matsumoto, A., Kubota, K., Kamisawa, T., Okazaki, K., Hirano, K., Hirooka, Y., Uchida, K., Masuda, A., Ohara, H., Shimizu, K., Arakura, N., Masamune, A., Kanno, A., Sakagami, J., Itoi, T., Ito, T., Ueki, T., Nishino, T. & 8 others, Inui, K., Mizuno, N., Yoshida, H., Sugiyama, M., Iwasaki, E., Irisawa, A., Shimosegawa, T. & Chiba, T., Jan 1 2019, In : Pancreas. 48, 1, p. 49-54 6 p.

Research output: Contribution to journalArticle

Pancreatitis
Intrahepatic Bile Ducts
Pancreatic Juice
Chronic Pancreatitis
Atrophy
2018
14 Citations (Scopus)

ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice

Kimura, Y., Fukuda, A., Ogawa, S., Maruno, T., Takada, Y., Tsuda, M., Hiramatsu, Y., Araki, O., Nagao, M., Yoshikawa, T., Ikuta, K., Yoshioka, T., Wang, Z., Akiyama, H., Wright, C. V., Takaori, K., Uemoto, S., Chiba, T. & Seno, H., Jul 2018, In : Gastroenterology. 155, 1, p. 194-209.e2

Research output: Contribution to journalArticle

Adenocarcinoma
Pancreatic Neoplasms
Neoplasms
Papillary Adenocarcinoma
S 6

Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice

Sakuma, Y., Kodama, Y., Eguchi, T., Uza, N., Tsuji, Y., Shiokawa, M., Maruno, T., Kuriyama, K., Nishikawa, Y., Yamauchi, Y., Tsuda, M., Ueda, T., Matsumori, T., Morita, T., Tomono, T., Kakiuchi, N., Mima, A., Sogabe, Y., Marui, S., Kuwada, T. & 5 others, Okada, A., Watanabe, T., Nakase, H., Chiba, T. & Seno, H., Dec 1 2018, In : Scientific reports. 8, 1, 8829.

Research output: Contribution to journalArticle

Ceruletide
Acinar Cells
Chemokines
Pancreatitis
Necrosis
4 Citations (Scopus)

Clinical course of type 1 autoimmune pancreatitis patients without steroid treatment: a Japanese multicenter study of 97 patients

Kubota, K., Kamisawa, T., Hirano, K., Hirooka, Y., Uchida, K., Ikeura, T., Shiomi, H., Ohara, H., Shimizu, K., Arakura, N., Kanno, A., Sakagami, J., Itoi, T., Ito, T., Ueki, T., Nishino, T., Inui, K., Mizuno, N., Yoshida, H., Sugiyama, M. & 7 others, Iwasaki, E., Irisawa, A., Okazaki, K., Kawa, S., Shimosegawa, T., Takeyama, Y. & Chiba, T., Apr 2018, In : Journal of Hepato-Biliary-Pancreatic Sciences. 25, 4, p. 223-230 8 p.

Research output: Contribution to journalArticle

Pancreatitis
Multicenter Studies
Steroids
Therapeutics
Recurrence

Colonoscopic removal of a denture migrated in the appendix

Ikeda, K., Nakamura, T., Uose, S., Someda, H. & Chiba, T., Mar 1 2018, In : Gastrointestinal endoscopy. 87, 3, p. 893-894 2 p.

Research output: Contribution to journalArticle

Dentures
7 Citations (Scopus)

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine

Muta, Y., Fujita, Y., Sumiyama, K., Sakurai, A., Taketo, M. M., Chiba, T., Seno, H., Aoki, K., Matsuda, M. & Imajo, M., Dec 1 2018, In : Nature communications. 9, 1, 2174.

Research output: Contribution to journalArticle

intestines
Extracellular Signal-Regulated MAP Kinases
Intestines
Tumors
tumors

Endoscopically resected long giant polypoidal lesion caused by arteriovenous malformation

Ikeda, K., Kishimoto, H., Uose, S., Nakamura, T. & Chiba, T., Oct 2018, In : Gastrointestinal endoscopy. 88, 4, p. 775-777 3 p.

Research output: Contribution to journalArticle

Arteriovenous Malformations
1 Citation (Scopus)

Evaluation of the safety and efficacy of endoscopic treatment for early gastric cancers in patients aged over 80 years

Setoyama, T., Miyamoto, SI., Nikaido, M., Horimatsu, T., Matsumoto, S., Ezoe, Y., Morita, S., Aoyama, I., Kawanami, C., Kusaka, T., Chiba, T., Muto, M. & Seno, H., Jan 1 2018, In : Journal of Japanese Society of Gastroenterology. 115, 5, p. 467-475 9 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Safety
Aspiration Pneumonia
Therapeutics
Incidence
7 Citations (Scopus)

Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study

Shirakashi, M., Yoshifuji, H., Kodama, Y., Chiba, T., Yamamoto, M., Takahashi, H., Uchida, K., Okazaki, K., Ito, T., Kawa, S., Yamada, K., Kawano, M., Hirata, S., Tanaka, Y., Moriyama, M., Nakamura, S., Kamisawa, T., Matsui, S., Tsuboi, H., Sumida, T. & 5 others, Shibata, M., Goto, H., Sato, Y., Yoshino, T. & Mimori, T., Dec 1 2018, In : Scientific reports. 8, 1, 10262.

Research output: Contribution to journalArticle

Open Access
Glucocorticoids
Multicenter Studies
Immunoglobulin G
Recurrence
Prednisolone
7 Citations (Scopus)

Gastrointestinal manifestation of immunoglobulin G4-related disease: clarification through a multicenter survey

Notohara, K., Kamisawa, T., Uchida, K., Zen, Y., Kawano, M., Kasashima, S., Sato, Y., Shiokawa, M., Uehara, T., Yoshifuji, H., Hayashi, H., Inoue, K., Iwasaki, K., Kawano, H., Matsubayashi, H., Moritani, Y., Murakawa, K., Oka, Y., Tateno, M., Okazaki, K. & 1 others, Chiba, T., Jul 1 2018, In : Journal of gastroenterology. 53, 7, p. 845-853 9 p.

Research output: Contribution to journalArticle

Immunoglobulins
Immunoglobulin G
Plasma Cell Granuloma
Gastrointestinal Diseases
Gastric Mucosa
1 Citation (Scopus)

Gene expression profile of Dclk1 + cells in intestinal tumors

Yamaga, Y., Fukuda, A., Nakanishi, Y., Goto, N., Matsumoto, Y., Yoshioka, T., Maruno, T., Chiba, T. & Seno, H., Dec 2018, In : Digestive and Liver Disease. 50, 12, p. 1353-1361 9 p.

Research output: Contribution to journalArticle

Transcriptome
Phosphotransferases
Neoplastic Stem Cells
Neoplasms
src-Family Kinases
31 Citations (Scopus)

Laminin 511 is a target antigen in autoimmune pancreatitis

Shiokawa, M., Kodama, Y., Sekiguchi, K., Kuwada, T., Tomono, T., Kuriyama, K., Yamazaki, H., Morita, T., Marui, S., Sogabe, Y., Kakiuchi, N., Matsumori, T., Mima, A., Nishikawa, Y., Ueda, T., Tsuda, M., Yamauchi, Y., Sakuma, Y., Maruno, T., Uza, N. & 4 others, Tsuruyama, T., Mimori, T., Seno, H. & Chiba, T., Aug 8 2018, In : Science Translational Medicine. 10, 453, eaaq0997.

Research output: Contribution to journalArticle

Pancreatitis
Antigens
Antibodies
Immunoglobulin G
Autoantibodies
4 Citations (Scopus)

Multiple roles of single-minded 2 in esophageal squamous cell carcinoma and its clinical implications

Tamaoki, M., Komatsuzaki, R., Komatsu, M., Minashi, K., Aoyagi, K., Nishimura, T., Chiwaki, F., Hiroki, T., Daiko, H., Morishita, K., Sakai, Y., Seno, H., Chiba, T., Muto, M., Yoshida, T. & Sasaki, H., Apr 2018, In : Cancer science. 109, 4, p. 1121-1134 14 p.

Research output: Contribution to journalArticle

Chemoradiotherapy
Aryl Hydrocarbon Receptor Nuclear Translocator
Neoplasms
DNA Repair Enzymes
Epithelial-Mesenchymal Transition
1 Citation (Scopus)

Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation

Kanda, K., Sakamoto, J., Matsumoto, Y., Ikuta, K., Goto, N., Morita, Y., Ohno, M., Nishi, K., Eto, K., Kimura, Y., Nakanishi, Y., Ikegami, K., Yoshikawa, T., Fukuda, A., Kawada, K., Sakai, Y., Ito, A., Yoshida, M., Kimura, T., Chiba, T. & 2 others, Nishi, E. & Seno, H., Apr 19 2018, In : JCI Insight. 3, 8

Research output: Contribution to journalArticle

Open Access
Carcinogenesis
Colonic Neoplasms
Epigenomics
Metalloendopeptidases
Epithelial Cells
1 Citation (Scopus)

Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice

Ikuta, K., Fukuda, A., Ogawa, S., Masuo, K., Goto, N., Hiramatsu, Y., Tsuda, M., Kimura, Y., Matsumoto, Y., Kimura, Y., Maruno, T., Kanda, K., Nishi, K., Takaori, K., Uemoto, S., Takaishi, S., Chiba, T., Nishi, E. & Seno, H., May 24 2018, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

Pancreatitis
Adenocarcinoma
Pancreas
Acinar Cells
Chronic Pancreatitis
4 Citations (Scopus)

Serum soluble interleukin-2 receptor as a biomarker in immunoglobulin G4-related disease

Handa, T., Matsui, S., Yoshifuji, H., Kodama, Y., Yamamoto, H., Minamoto, S., Waseda, Y., Sato, Y., Kubo, K., Mimori, T., Chiba, T., Hirai, T. & Mishima, M., Sep 3 2018, In : Modern Rheumatology. 28, 5, p. 838-844 7 p.

Research output: Contribution to journalArticle

Interleukin-2 Receptors
Immunoglobulins
Interleukin-2
Biomarkers
Serum
8 Citations (Scopus)

The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis

Tsuda, M., Fukuda, A., Roy, N., Hiramatsu, Y., Leonhardt, L., Kakiuchi, N., Hoyer, K., Ogawa, S., Goto, N., Ikuta, K., Kimura, Y., Matsumoto, Y., Takada, Y., Yoshioka, T., Maruno, T., Yamaga, Y., Kim, G. E., Akiyama, H., Ogawa, S., Wright, C. V. & 6 others, Saur, D., Takaori, K., Uemoto, S., Hebrok, M., Chiba, T. & Seno, H., Aug 1 2018, In : Journal of Clinical Investigation. 128, 8, p. 3475-3489 15 p.

Research output: Contribution to journalArticle

Acinar Cells
Carcinogenesis
Adenocarcinoma
Genes
Pancreatic Neoplasms
2017
2 Citations (Scopus)

Activation of TNF-α-AID axis and co-inhibitory signals in coordination with Th1-type immunity in a mouse model recapitulating hepatitis B

Matsumoto, T., Takahashi, K., Inuzuka, T., Kim, S. K., Kurosaki, T., Kawakami, S., Chiba, T., Seno, H. & Marusawa, H., Mar 1 2017, In : Antiviral Research. 139, p. 138-145 8 p.

Research output: Contribution to journalArticle

Hepatitis B
Hepatitis B virus
Immunity
Virus Diseases
Tumor Necrosis Factor-alpha
34 Citations (Scopus)

Clinical Features, Response to Treatment, and Outcomes of IgG4-Related Sclerosing Cholangitis

Tanaka, A., Tazuma, S., Okazaki, K., Nakazawa, T., Inui, K., Chiba, T. & Takikawa, H., Jun 2017, In : Clinical Gastroenterology and Hepatology. 15, 6, p. 920-926.e3

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Immunoglobulins
Japan
Cholangiocarcinoma
Prednisolone
47 Citations (Scopus)

Current approach to the diagnosis of IgG4-related disease–Combination of comprehensive diagnostic and organ-specific criteria

Umehara, H., Okazaki, K., Nakamura, T., Satoh-Nakamura, T., Nakajima, A., Kawano, M., Mimori, T. & Chiba, T., May 4 2017, In : Modern Rheumatology. 27, 3, p. 381-391 11 p.

Research output: Contribution to journalReview article

Immunoglobulin G
Pancreatitis
Mikulicz' Disease
Orbital Diseases
Retroperitoneal Fibrosis
8 Citations (Scopus)

Diagnostic performance of a new endoscopic scraper for malignant biliary strictures: a multicenter prospective study

for the Kyoto Pancreatobiliary Study Group & Kyoto Pancreatobiliary Study Group, Feb 1 2017, In : Gastrointestinal endoscopy. 85, 2, p. 371-379 9 p.

Research output: Contribution to journalArticle

Multicenter Studies
Surgical Instruments
Pathologic Constriction
Prospective Studies
Equipment and Supplies
12 Citations (Scopus)

Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

Yoshioka, M., Ohashi, S., Ida, T., Nakai, Y., Kikuchi, O., Amanuma, Y., Matsubara, J., Yamada, A., Miyamoto, SI., Natsuizaka, M., Nakagawa, H., Chiba, T., Seno, H. & Muto, M., Aug 1 2017, In : Journal of Experimental and Clinical Cancer Research. 36, 1, 101.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Epithelial Cells
Esophageal Squamous Cell Carcinoma
Heterografts
Phenotype
4 Citations (Scopus)

Distinct roles of HES1 in normal stem cells and tumor stem-like cells of the intestine

Goto, N., Ueo, T., Fukuda, A., Kawada, K., Sakai, Y., Miyoshi, H., Taketo, M. M., Chiba, T. & Seno, H., Jul 1 2017, In : Cancer research. 77, 13, p. 3442-3454 13 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Intestines
Stem Cells
Neoplasms
Homeostasis
3 Citations (Scopus)

Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis

Tsuji, Y., Takahashi, N., Isoda, H., Koizumi, K., Koyasu, S., Sekimoto, M., Imanaka, Y., Yazumi, S., Asada, M., Nishikawa, Y., Yamamoto, H., Kikuchi, O., Yoshida, T., Inokuma, T., Katsushima, S., Esaka, N., Okano, A., Kawanami, C., Kakiuchi, N., Shiokawa, M. & 5 others, Kodama, Y., Moriyama, I., Kajitani, T., Kinoshita, Y. & Chiba, T., Oct 1 2017, In : Journal of gastroenterology. 52, 10, p. 1130-1139 10 p.

Research output: Contribution to journalArticle

Pancreatitis
Early Diagnosis
Necrosis
Perfusion
Area Under Curve
2 Citations (Scopus)

Erratum to: Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis (Journal of Gastroenterology, (2017), 52, 10, (1130-1139), 10.1007/s00535-017-1330-5)

Tsuji, Y., Takahashi, N., Isoda, H., Koizumi, K., Koyasu, S., Sekimoto, M., Imanaka, Y., Yazumi, S., Asada, M., Nishikawa, Y., Yamamoto, H., Kikuchi, O., Yoshida, T., Inokuma, T., Katsushima, S., Esaka, N., Okano, A., Kawanami, C., Kakiuchi, N., Shiokawa, M. & 5 others, Kodama, Y., Moriyama, I., Kajitani, T., Kinoshita, Y. & Chiba, T., Oct 1 2017, In : Journal of gastroenterology. 52, 10, p. 1147-1148 2 p.

Research output: Contribution to journalComment/debate

Gastroenterology
Pancreatitis
Names
Early Diagnosis
Necrosis
8 Citations (Scopus)

Helicobacter pylori-mediated genetic instability and gastric carcinogenesis

Shimizu, T., Chiba, T. & Marusawa, H., Jan 1 2017, Current Topics in Microbiology and Immunology. Springer Verlag, p. 305-323 19 p. (Current Topics in Microbiology and Immunology; vol. 400).

Research output: Chapter in Book/Report/Conference proceedingChapter

Helicobacter pylori
Stomach
Carcinogenesis
Helicobacter Infections
Stomach Neoplasms
14 Citations (Scopus)

How to diagnose IgG4-related disease

Umehara, H., Okazaki, K., Kawano, M., Mimori, T. & Chiba, T., Nov 1 2017, In : Annals of the rheumatic diseases. 76, 11, e46.

Research output: Contribution to journalLetter

Biomarkers
Adrenal Cortex Hormones
Immunoglobulin G
25 Citations (Scopus)

Low-dose maintenance steroid treatment could reduce the relapse rate in patients with type 1 autoimmune pancreatitis: a long-term Japanese multicenter analysis of 510 patients

Kubota, K., Kamisawa, T., Okazaki, K., Kawa, S., Hirano, K., Hirooka, Y., Uchida, K., Shiomi, H., Ohara, H., Shimizu, K., Arakura, N., Kanno, A., Sakagami, J., Itoi, T., Ito, T., Ueki, T., Nishino, T., Inui, K., Mizuno, N., Yoshida, H. & 6 others, Sugiyama, M., Iwasaki, E., Irisawa, A., Shimosegawa, T., Takeyama, Y. & Chiba, T., Aug 1 2017, In : Journal of gastroenterology. 52, 8, p. 955-964 10 p.

Research output: Contribution to journalArticle

Pancreatitis
Steroids
Maintenance
Recurrence
Therapeutics
6 Citations (Scopus)

Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach

Kimura, Y., Ikuta, K., Kimura, T., Chiba, T., Oshima, H., Oshima, M., Nishi, E. & Seno, H., Feb 23 2017, In : Scientific reports. 7, 43052.

Research output: Contribution to journalArticle

Metaplasia
Stomach
Inflammation
Neoplasms
Helicobacter felis
9 Citations (Scopus)

Proliferating EpCAM-positive ductal cells in the inflamed liver give rise to hepatocellular carcinoma

Matsumoto, T., Takai, A., Eso, Y., Kinoshita, K., Manabe, T., Seno, H., Chiba, T. & Marusawa, H., Nov 15 2017, In : Cancer Research. 77, 22, p. 6131-6143 13 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Liver
Hepatocytes
Epithelial Cell Adhesion Molecule
Carcinoma
2016
14 Citations (Scopus)

A retrospective analysis on the utility and complications of upper arm ports in 433 cases at a single institute

Mori, Y., Nagayama, S., Kawamura, J. I., Hasegawa, S., Tanaka, E., Okabe, H., Takeuchi, M., Sonobe, M., Matsumoto, S., Kanai, M., Muto, M., Chiba, T. & Sakai, Y., Jun 1 2016, In : International Journal of Clinical Oncology. 21, 3, p. 474-482 9 p.

Research output: Contribution to journalArticle

Arm
Catheters
Thorax
Medical Records
Thrombosis
7 Citations (Scopus)

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling

Takada, Y., Fukuda, A., Chiba, T. & Seno, H., Oct 1 2016, In : Development (Cambridge). 143, 19, p. 3532-3539 8 p.

Research output: Contribution to journalArticle

Duodenum
Homeostasis
Stem Cells
Morphogenesis
Apoptosis
3 Citations (Scopus)

Concomitant Case of Intraductal Papillary Mucinous Neoplasm of the Pancreas and Functioning Pancreatic Neuroendocrine Tumor (Vasoactive Intestinal Polypeptide-Producing Tumor): First Report

Ishizu, S., Setoyama, T., Ueo, T., Ueda, Y., Kodama, Y., Ida, H., Kawaguchi, Y., Yoshizawa, A., Chiba, T. & Miyamoto, SI., Jul 1 2016, In : Pancreas. 45, 6, p. e24-e25

Research output: Contribution to journalLetter

Multiple Primary Neoplasms
Pancreatic Ductal Carcinoma
Neuroendocrine Tumors
Vasoactive Intestinal Peptide
Pancreatic Neoplasms
15 Citations (Scopus)

Impact of EUS-FNA for preoperative para-aortic lymph node staging in patients with pancreatobiliary cancer

Kurita, A., Kodama, Y., Nakamoto, Y., Isoda, H., Minamiguchi, S., Yoshimura, K., Kuriyama, K., Sawai, Y., Uza, N., Hatano, E., Uemoto, S., Togashi, K., Haga, H. & Chiba, T., Sep 1 2016, In : Gastrointestinal endoscopy. 84, 3, p. 467-475.e1

Research output: Contribution to journalArticle

Endoscopic Ultrasound-Guided Fine Needle Aspiration
Lymph Nodes
Neoplasm Metastasis
Positron-Emission Tomography
Neoplasms

Involvement of gene abnormalities in the development of digestive diseases

Chiba, T. & Seno, H., Jan 1 2016, In : Journal of Japanese Society of Gastroenterology. 113, 11, p. 1849-1856 8 p.

Research output: Contribution to journalReview article

Genes
8 Citations (Scopus)

Long-term efficacy of hepatitis B vaccination as post-transplant prophylaxis in hepatitis B surface antigen (HBsAg) positive recipients and HBsAg negative recipients of anti-hepatitis B core positive grafts

Yoshizawa, A., Yamashiki, N., Ueda, Y., Kaido, T., Okajima, H., Marusawa, H., Chiba, T. & Uemoto, S., May 1 2016, In : Hepatology Research. 46, 6, p. 541-551 11 p.

Research output: Contribution to journalArticle

Hepatitis B Surface Antigens
Hepatitis B
Hepatitis B virus
Vaccination
Transplants
7 Citations (Scopus)

MSH2 dysregulation is triggered by proinflammatory cytokine stimulation and is associated with liver cancer development

Eso, Y., Takai, A., Matsumoto, T., Inuzuka, T., Horie, T., Ono, K., Uemoto, S., Lee, K., Edelmann, W., Chiba, T. & Marusawa, H., Aug 1 2016, In : Cancer research. 76, 15, p. 4383-4393 11 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Cytokines
Inflammation
Hepatocytes
DNA Mismatch Repair
7 Citations (Scopus)

Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma

Kikuchi, O., Ohashi, S., Horibe, T., Kohno, M., Nakai, Y., Miyamoto, SI., Chiba, T., Muto, M. & Kawakami, K., Mar 9 2016, In : Scientific reports. 6, 22452.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Peptides
Peptide Fragments
Esophageal Squamous Cell Carcinoma
Neoplasms
13 Citations (Scopus)

Nucleotide-binding oligomerization domain 1 acts in concert with the cholecystokinin receptor agonist, cerulein, to induce IL-33-dependent chronic pancreatitis

Watanabe, T., Sadakane, Y., Yagama, N., Sakurai, T., Ezoe, H., Kudo, M., Chiba, T. & Strober, W., Sep 1 2016, In : Mucosal Immunology. 9, 5, p. 1234-1249 16 p.

Research output: Contribution to journalArticle

Cholecystokinin Receptors
Ceruletide
Chronic Pancreatitis
Nucleotides
Inflammation
60 Citations (Scopus)

Pathogenicity of IgG in patients with IgG4-related disease

Shiokawa, M., Kodama, Y., Kuriyama, K., Yoshimura, K., Tomono, T., Morita, T., Kakiuchi, N., Matsumori, T., Mima, A., Nishikawa, Y., Ueda, T., Tsuda, M., Yamauchi, Y., Minami, R., Sakuma, Y., Ota, Y., Maruno, T., Kurita, A., Sawai, Y., Tsuji, Y. & 7 others, Uza, N., Matsumura, K., Watanabe, T., Notohara, K., Tsuruyama, T., Seno, H. & Chiba, T., Aug 1 2016, In : Gut. 65, 8, p. 1322-1332 11 p.

Research output: Contribution to journalArticle

Virulence
Immunoglobulin G
Pancreatitis
Organ Culture Techniques
Wounds and Injuries
22 Citations (Scopus)

Prognostic model for survival based on readily available pretreatment factors in patients with advanced pancreatic cancer receiving palliative chemotherapy

Kou, T., Kanai, M., Yamamoto, M., Xue, P., Mori, Y., Kudo, Y., Kurita, A., Uza, N., Kodama, Y., Asada, M., Kawaguchi, M., Masui, T., Mizumoto, M., Yazumi, S., Matsumoto, S., Takaori, K., Morita, S., Muto, M., Uemoto, S. & Chiba, T., Feb 1 2016, In : International Journal of Clinical Oncology. 21, 1, p. 118-125 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Drug Therapy
Survival
Carcinoembryonic Antigen
Calibration
14 Citations (Scopus)

TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma

Ki Kim, S., Ueda, Y., Hatano, E., Kakiuchi, N., Takeda, H., Goto, T., Shimizu, T., Yoshida, K., Ikura, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Uemoto, S., Chiba, T., Ogawa, S. & Marusawa, H., Dec 1 2016, In : International Journal of Cancer. 139, 11, p. 2512-2518 7 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Chromosomes
Mutation
Exome
Genes