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    Dimitrios P Kontoyiannis
2019

Acute acalculous cholecystitis due to Fusarium species and review of the literature on fungal cholecystitis

Szvalb, A. D. & Kontoyiannis, D. P., Jan 1 2019, In : Mycoses. 62, 9, p. 847-853 7 p.

Research output: Contribution to journalReview article

Acalculous Cholecystitis
Acute Cholecystitis
Cholecystitis
Fusarium
Fusariosis

A murine model of cutaneous aspergillosis for evaluation of biomaterials-based local delivery therapies

Tatara, A. M., Watson, E., Albert, N. D., Kontoyiannis, P. D., Kontoyiannis, D. P. & Mikos, A. G., Sep 2019, In : Journal of Biomedical Materials Research - Part A. 107, 9, p. 1867-1874 8 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Biomaterials
Defects
Biodegradable polymers
Aspergillus
Triazoles
Aspergillus fumigatus
Real-Time Polymerase Chain Reaction
Alleles
Mutation
Invasive Pulmonary Aspergillosis
Hematologic Neoplasms
Aspergillus
Aspergillus fumigatus
Serum
1 Citation (Scopus)

Checkpoint Inhibition and Infectious Diseases: A Good Thing?

Abers, M. S., Lionakis, M. S. & Kontoyiannis, D. P., Dec 2019, In : Trends in Molecular Medicine. 25, 12, p. 1080-1093 14 p.

Research output: Contribution to journalReview article

Communicable Diseases
Programmed Cell Death 1 Receptor
Neoplasms
Cytotoxic T-Lymphocytes
Infection
1 Citation (Scopus)
Phaeohyphomycosis
Fusariosis
Mucormycosis
Aspergillosis
Mucorales
Clostridium difficile
Microbiology
Candida
Interviews
Confusion

Corrigendum: Azole-resistance in aspergillus terreusand related species: An emerging problem or a rare phenomenon? (Frontiers in Microbiology (2018) 9 (516) DOI: 10.3389/fmicb.2018.00516)

Zoran, T., Sartori, B., Sappl, L., Aigner, M., Sánchez-Reus, F., Rezusta, A., Chowdhary, A., Taj-Aldeen, S. J., Arendrup, M. C., Oliveri, S., Kontoyiannis, D. P., Alastruey-Izquierdo, A., Lagrou, K., Lo Cascio, G., Meis, J. F., Buzina, W., Farina, C., Drogari-Apiranthitou, M., Grancini, A., Tortorano, A. M. & 34 others, Willinger, B., Hamprecht, A., Johnson, E., Klingspor, L., Arsic-Arsenijevic, V., Cornely, O. A., Meletiadis, J., Prammer, W., Tullio, V., Vehreschild, J. J., Trovato, L., Lewis, R. E., Segal, E., Rath, P. M., Hamal, P., Rodriguez-Iglesias, M., Roilides, E., Arikan-Akdagli, S., Chakrabarti, A., Colombo, A. L., Fernández, M. S., Martin-Gomez, M. T., Badali, H., Petrikkos, G., Klimko, N., Heimann, S. M., Uzun, O., Roudbary, M., De La Fuente, S., Houbraken, J., Risslegger, B., Sabino, R., Lass-Flörl, C. & Lackner, M., Jan 1 2019, In : Frontiers in Microbiology. 10, JAN, 3245.

Research output: Contribution to journalComment/debate

Open Access
Azoles
Aspergillus
Microbiology
corrigendum
1 Citation (Scopus)

Culture-documented invasive mold infections at md anderson cancer center in houston, Texas, pre- And post-hurricane harvey

Kontoyiannis, D. P., Shah, E. C., Wurster, S., Aitken, S. L., Graviss, L., Raad, I. I. & Chemaly, R. F., Apr 2019, In : Open Forum Infectious Diseases. 6, 4

Research output: Contribution to journalArticle

Open Access
Cyclonic Storms
Fungi
Infection
Neoplasms
Microbiology
Hemolytic Anemia
B-Cell Chronic Lymphocytic Leukemia
Cytomegalovirus
5 Citations (Scopus)

Defining breakthrough invasive fungal infection–Position paper of the mycoses study group education and research consortium and the European Confederation of Medical Mycology

for the Mycoses Study Group Education and Research Consortium (MSG-ERC) and the European Confederation of Medical Mycology (ECMM), Jan 1 2019, In : Mycoses. 62, 9, p. 716-729 14 p.

Research output: Contribution to journalReview article

Mycology
Mycoses
Education
Research
Invasive Fungal Infections

Development and internal validation of a model for predicting 60-day risk of invasive mould disease in patients with haematological malignancies

Stanzani, M., Vianelli, N., Cavo, M., Kontoyiannis, D. P. & Lewis, R. E., Jun 1 2019, In : Journal of Infection. 78, 6, p. 484-490 7 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Fungi
Lymphopenia
Hematology
Disease Management

Drosophila melanogaster as a model to study virulence and azole treatment of the emerging pathogen Candida auris

Wurster, S., Bandi, A., Beyda, N. D., Albert, N. D., Raman, N. M., Raad, I. I. & Kontoyiannis, D. P., Jul 1 2019, In : Journal of Antimicrobial Chemotherapy. 74, 7, p. 1904-1910 7 p.

Research output: Contribution to journalArticle

Azoles
Drosophila melanogaster
Candida
Diptera
Virulence

Fecal microbiome, metabolites, and stem cell transplant outcomes: A single-center pilot study

Galloway-Peña, J. R., Peterson, C. B., Malik, F., Sahasrabhojane, P. V., Shah, D. P., Brumlow, C. E., Carlin, L. G., Chemaly, R. F., Im, J. S., Rondon, G., Felix, E., Veillon, L., Lorenzi, P. L., Alousi, A. M., Jenq, R. R., Kontoyiannis, D. P., Shpall, E. J., Shelburne, S. A. & Okhuysen, P. C., Jan 1 2019, In : Open Forum Infectious Diseases. 6, 5

Research output: Contribution to journalArticle

Open Access
Microbiota
Butyrates
Hematopoietic Stem Cells
Stem Cells
Transplants

Germline genetic predisposition to myeloid neoplasia from GATA2 gene mutations: Lessons learned from two cases

Dalle, I. A., Bannon, S. A., Patel, K. P., Routbort, M. J., Cortes, J. E., Ferrajoli, A., Kontoyiannis, D. P., Wang, S. A. & DiNardo, C. D., Jan 1 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hurricane-associated mold exposures among patients at risk for invasive mold infections after hurricane harvey — Houston, Texas, 2017

Chow, N. A., Toda, M., Pennington, A. F., Anassi, E., Atmar, R. L., Cox-Ganser, J. M., Da Silva, J., Garcia, B., Kontoyiannis, D. P., Ostrosky-Zeichner, L., Leining, L. M., McCarty, J., Mohajer, M. A., Murthy, B. P., Park, J. H., Schulte, J., Shuford, J. A., Skrobarcek, K. A., Solomon, S., Strysko, J. & 4 others, Chiller, T. M., Jackson, B. R., Chew, G. L. & Beer, K. D., May 31 2019, In : Morbidity and Mortality Weekly Report. 68, 21, p. 470-473 4 p.

Research output: Contribution to journalArticle

Cyclonic Storms
Environmental Exposure
Immunocompromised Host
Disasters
risk assessment

Is Candida auris here to stay? An interview with Dimitrios Kontoyiannis

Kontoyiannis, D. P., Jan 1 2019, In : Future Microbiology. 14, 13, p. 1083-1085 3 p.

Research output: Contribution to journalReview article

Open Access
Mycology
Candida
Interviews
Manuscripts
Immunocompromised Host
1 Citation (Scopus)

Lack of Toxicity with Long-term Isavuconazole Use in Patients with Hematologic Malignancy

Dipippo, A. J. & Kontoyiannis, D. P., Oct 15 2019, In : Clinical Infectious Diseases. 69, 9, p. 1624-1627 4 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Triazoles
Immunocompromised Host
Population
isavuconazole

Live monitoring and analysis of fungal growth, viability, and mycelial morphology using the incucyte neurotrack processing module

Wurster, S., Kumaresan, P. R., Albert, N. D., Hauser, P. J., Lewis, R. E. & Kontoyiannis, D. P., May 1 2019, In : mBio. 10, 3, e00673-19.

Research output: Contribution to journalArticle

Open Access
Fungi
Morphogenesis
Growth
Coculture Techniques
Candida albicans
1 Citation (Scopus)

Mucormycosis of the central nervous system

Chikley, A., Ben-Ami, R. & Kontoyiannis, D. P., Sep 2019, In : Journal of Fungi. 5, 3, 59.

Research output: Contribution to journalArticle

Open Access
Mucormycosis
nervous system
central nervous system
Central Nervous System
diabetes
6 Citations (Scopus)

Multimaterial segmented fiber printing for gradient tissue engineering

Diaz-Gomez, L., Smith, B. T., Kontoyiannis, P. D., Bittner, S. M., Melchiorri, A. J. & Mikos, A. G., Jan 2019, In : Tissue Engineering - Part C: Methods. 25, 1, p. 12-24 13 p.

Research output: Contribution to journalArticle

Printing
Durapatite
Tissue Engineering
Tissue engineering
Scaffolds

Myeloid malignancies with somatic GATA2 mutations can be associated with an immunodeficiency phenotype

Alfayez, M., Wang, S. A., Bannon, S. A., Kontoyiannis, D. P., Kornblau, S. M., Orange, J. S., Mace, E. M. & DiNardo, C. D., Jul 3 2019, In : Leukemia and Lymphoma. 60, 8, p. 2025-2033 9 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Phenotype
Mutation
Neoplasms
Genetic Testing
3 Citations (Scopus)

Necrotizing mucormycosis ofwounds following combat injuries, natural disasters, burns, and other trauma

Walsh, T. J., Hospenthal, D. R., Petraitis, V. & Kontoyiannis, D. P., Sep 2019, In : Journal of Fungi. 5, 3, 57.

Research output: Contribution to journalReview article

Open Access
Saksenaea
Absidia
debridement
disasters
natural disaster

Nitroglycerin-Citrate-Ethanol Catheter Lock Solution Is Highly Effective for in Vitro Eradication of Candida auris Biofilm

Vargas-Cruz, N., Reitzel, R. A., Rosenblatt, J., Chaftari, A-M. P., Dib, R. W., Hachem, R. Y., Kontoyiannis, D. P. & Raad, I. I., Jan 1 2019, In : Antimicrobial Agents and Chemotherapy. 63, 7, e00299-19.

Research output: Contribution to journalArticle

Nitroglycerin
Biofilms
Candida
Citric Acid
Ethanol
2 Citations (Scopus)

Nivolumab–induced encephalitis post allogeneic stem cell transplant in a patient with Hodgkin’s disease

De la Hoz, A., Foolad, F., Gallegos, C., Kornblau, S. M. & Kontoyiannis, D. P., May 1 2019, In : Bone marrow transplantation. 54, 5, p. 749-751 3 p.

Research output: Contribution to journalLetter

Encephalitis
Hodgkin Disease
Stem Cells
Transplants
nivolumab
6 Citations (Scopus)

On the emergence of candida auris: climate change, azoles, swamps, and birds

Casadevall, A., Kontoyiannis, D. P. & Robert, V., Jan 1 2019, In : mBio. 10, 4, e01397-19.

Research output: Contribution to journalArticle

Open Access
Azoles
Mycoses
Wetlands
Climate Change
Candida
1 Citation (Scopus)
Mucorales
Aspergillus fumigatus
Drosophila melanogaster
Virulence
Mucormycosis
2 Citations (Scopus)
B-Cell Chronic Lymphocytic Leukemia
Coccidioides
Therapeutics
Actinic Keratosis
Triazoles

Screening the in vitro susceptibility of posaconazole in clinical isolates of Candida spp. and Aspergillus spp. and analyzing the sequence of ERG11 or CYP51A in non-wild-type isolates from China

Zhang, H., Tan, J., Kontoyiannis, D. P., Zhou, Y., Liu, W., Zhu, P., Shi, X., Wan, Z., Li, R. & Liu, W., Oct 2019, In : Diagnostic Microbiology and Infectious Disease. 95, 2, p. 166-170 5 p.

Research output: Contribution to journalArticle

Aspergillus
Candida
China
Triazoles
Candida tropicalis
1 Citation (Scopus)

Serum levels of crushed posaconazole delayed-release tablets

Mason, M. J., McDaneld, P. M., Musick, W. L. & Kontoyiannis, D. P., May 2019, In : Antimicrobial Agents and Chemotherapy. 63, 5, e02688-18.

Research output: Contribution to journalShort survey

Drug Monitoring
Tablets
Serum
posaconazole

Therapeutic challenges of non-Aspergillus invasive mold infections in immunosuppressed patients

Lamoth, F. & Kontoyiannis, D. P., Jan 1 2019, In : Antimicrobial Agents and Chemotherapy. 63, 11, e01244-19.

Research output: Contribution to journalArticle

Fungi
Infection
Pharmaceutical Preparations
Therapeutics
Mucorales
4 Citations (Scopus)

Three-Dimensional Printing of Tissue Engineering Scaffolds with Horizontal Pore and Composition Gradients

Diaz-Gomez, L., Kontoyiannis, P. D., Melchiorri, A. J. & Mikos, A. G., Jul 2019, In : Tissue Engineering - Part C: Methods. 25, 7, p. 411-420 10 p.

Research output: Contribution to journalArticle

3D printers
Tissue Scaffolds
Porosity
Durapatite
Tissue Engineering
6 Citations (Scopus)

Tolerability of isavuconazole after posaconazole toxicity in leukaemia patients

DiPippo, A. J., Rausch, C. R. & Kontoyiannis, D. P., Jan 2019, In : Mycoses. 62, 1, p. 81-86 6 p.

Research output: Contribution to journalArticle

Leukemia
Liver Function Tests
isavuconazole
posaconazole
Therapeutics
1 Citation (Scopus)
Drug Monitoring
Tablets
Suspensions
Phase III Clinical Trials
posaconazole
2018
1 Citation (Scopus)

Acute myeloid leukemia and the infectious diseases consultant

Mulanovich, V. & Kontoyiannis, D. P., Jun 3 2018, In : Leukemia and Lymphoma. 59, 6, p. 1284-1291 8 p.

Research output: Contribution to journalReview article

Consultants
Acute Myeloid Leukemia
Communicable Diseases
Polypharmacy
Infection Control
17 Citations (Scopus)

Advances in the diagnosis and treatment of fungal infections of the CNS

Schwartz, S., Kontoyiannis, D. P., Harrison, T. & Ruhnke, M., Apr 1 2018, In : The Lancet Neurology. 17, 4, p. 362-372 11 p.

Research output: Contribution to journalReview article

Mycoses
Fungi
Therapeutics
Knowledge Management
Cryptococcus
3 Citations (Scopus)

A New Method for Reactivating and Expanding T Cells Specific for Rhizopus oryzae

Castillo, P., Wright, K. E., Kontoyiannis, D. P., Walsh, T., Patel, S., Chorvinsky, E., Bose, S., Hazrat, Y., Omer, B., Albert, N., Leen, A. M., Rooney, C. M., Bollard, C. M. & Cruz, C. R. Y., Jun 15 2018, In : Molecular Therapy - Methods and Clinical Development. 9, p. 305-312 8 p.

Research output: Contribution to journalArticle

Rhizopus
T-Lymphocytes
Mucormycosis
Fungal Antigens
Tissue Donors
5 Citations (Scopus)
Induction Chemotherapy
Acute Myeloid Leukemia
Inflammation
Remission Induction
Sleep Stages
15 Citations (Scopus)

Azole-resistance in Aspergillus terreus and related species: An emerging problem or a rare Phenomenon?

Zoran, T., Sartori, B., Sappl, L., Aigner, M., Sánchez-Reus, F., Rezusta, A., Chowdhary, A., Taj-Aldeen, S. J., Arendrup, M. C., Oliveri, S., Kontoyiannis, D. P., Alastruey-Izquierdo, A., Lagrou, K., Cascio, G. L., Meis, J. F., Buzina, W., Farina, C., Drogari-Apiranthitou, M., Grancini, A., Tortorano, A. M. & 33 others, Willinger, B., Hamprecht, A., Johnson, E., Klingspor, L., Arsic-Arsenijevic, V., Cornely, O. A., Meletiadis, J., Prammer, W., Tullio, V., Vehreschild, J. J., Trovato, L., Lewis, R. E., Segal, E., Rath, P. M., Hamal, P., Rodriguez-Iglesias, M., Roilides, E., Arikan-Akdagli, S., Chakrabarti, A., Colombo, A. L., Fernández, M. S., Martin-Gomez, M. T., Badali, H., Petrikkos, G., Klimko, N., Heimann, S. M., Uzun, O., Roudbary, M., de la Fuente, S., Houbraken, J., Risslegger, B., Lass-Flörl, C. & Lackner, M., Mar 28 2018, In : Frontiers in Microbiology. 9, MAR, 516.

Research output: Contribution to journalArticle

Azoles
Aspergillus
Itraconazole
Germany
Phenotype
18 Citations (Scopus)

Breakthrough fungal infections in patients with leukemia receiving isavuconazole

Rausch, C. R., Dipippo, A. J., Bose, P. & Kontoyiannis, D. P., Oct 30 2018, In : Clinical Infectious Diseases. 67, 10, p. 1610-1613 4 p.

Research output: Contribution to journalArticle

Mycoses
Leukemia
Mucormycosis
Candidiasis
Neutropenia
19 Citations (Scopus)

Breakthrough invasive mold infections in the hematology patient: Current concepts and future directions

Lionakis, M. S., Lewis, R. E. & Kontoyiannis, D. P., Oct 30 2018, In : Clinical Infectious Diseases. 67, 10, p. 1621-1630 10 p.

Research output: Contribution to journalArticle

Hematology
Fungi
Hematopoietic Stem Cell Transplantation
Infection
Mycology
Invasive Pulmonary Aspergillosis
Hematologic Diseases
Methenamine
Bronchoalveolar Lavage Fluid
Silver Staining
9 Citations (Scopus)

Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis

Kyrmizi, I., Ferreira, H., Carvalho, A., Figueroa, J. A. L., Zarmpas, P., Cunha, C., Akoumianaki, T., Stylianou, K., Deepe, G. S., Samonis, G., Lacerda, J. F., Campos, A., Kontoyiannis, D. P., Mihalopoulos, N., Kwon-Chung, K. J., El-Benna, J., Valsecchi, I., Beauvais, A., Brakhage, A. A., Neves, N. M. & 2 others, Latge, J. P. & Chamilos, G., Jul 1 2018, In : Nature microbiology. 3, 7, p. 791-803 13 p.

Research output: Contribution to journalArticle

Calcium Signaling
Melanins
Calmodulin
Phagocytosis
Phagosomes
62 Citations (Scopus)
Phosphotransferases
Pneumocystis carinii
Cryptococcus neoformans
Opportunistic Infections
Immunosuppressive Agents

Clinical Approach to Infections in the Compromised Host

Shelburne, S., Lewis, R. E. & Kontoyiannis, D. P., Jan 1 2018, Hematology: Basic Principles and Practice. Elsevier Inc., p. 1447-1461 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Febrile Neutropenia
Infection

Clinical Course of Preseptal and Orbital Cellulitis in 50 Immunocompromised Patients with Cancer

Sagiv, O., Thakar, S. D., Kandl, T. J., Kontoyiannis, D. P., Debnam, J. M. & Esmaeli, B., Feb 2018, In : Ophthalmology. 125, 2, p. 318-320 3 p.

Research output: Contribution to journalArticle

Orbital Cellulitis
Immunocompromised Host
Neoplasms
38 Citations (Scopus)

Detecting Infections Rapidly and Easily for Candidemia Trial, Part 2 (DIRECT2): A Prospective, Multicenter Study of the T2Candida Panel

Clancy, C. J., Pappas, P. G., Vazquez, J., Judson, M. A., Kontoyiannis, D. P., Thompson, G. R., Garey, K. W., Reboli, A., Greenberg, R. N., Apewokin, S., Lyon, G. M., Ostrosky-Zeichner, L., Wu, A. H. B., Tobin, E., Nguyen, M. H. & Caliendo, A. M., May 17 2018, In : Clinical Infectious Diseases. 66, 11, p. 1678-1686 9 p.

Research output: Contribution to journalArticle

Candidemia
Multicenter Studies
Candida
Prospective Studies
Candida albicans
10 Citations (Scopus)

Drug delivery and tissue engineering to promote wound healing in the immunocompromised host: Current challenges and future directions

Tatara, A. M., Kontoyiannis, D. P. & Mikos, A. G., Apr 1 2018, In : Advanced Drug Delivery Reviews. 129, p. 319-329 11 p.

Research output: Contribution to journalReview article

Immunocompromised Host
Tissue Engineering
Wound Healing
Pharmaceutical Preparations
Regenerative Medicine

Econazole-releasing porous space maintainers for fungal periprosthetic joint infection

Tatara, A. M., Rozich, A. J., Kontoyiannis, P. D., Watson, E., Albert, N. D., Bennett, G. N. & Mikos, A. G., May 1 2018, In : Journal of Materials Science: Materials in Medicine. 29, 5, 70.

Research output: Contribution to journalArticle

Econazole
Antibiotics
Bioactivity
Repair
Joints
1 Citation (Scopus)

Erratum to: Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species (Nature Communications, (2018), 9, 1, (3333), 10.1038/s41467-018-05820-2)

Andrianaki, A. M., Kyrmizi, I., Thanopoulou, K., Baldin, C., Drakos, E., Soliman, S. S. M., Shetty, A. C., McCracken, C., Akoumianaki, T., Stylianou, K., Ioannou, P., Pontikoglou, C., Papadaki, H. A., Tzardi, M., Belle, V., Etienne, E., Beauvais, A., Samonis, G., Kontoyiannis, D. P., Andreakos, E. & 3 others, Bruno, V. M., Ibrahim, A. S. & Chamilos, G., Dec 1 2018, In : Nature communications. 9, 1, 5015.

Research output: Contribution to journalComment/debate

rhizopus
Rhizopus
macrophages
Alveolar Macrophages
constrictions