A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone

David L. Waning; Theresa A. Guise; Khalid S. Mohammad

doi:10.1016/j.cmet.2018.12.014

A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone

David L. Waning, Theresa A. Guise, Khalid S. Mohammad

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

Abstract

Tumor cell interactions with the bone microenvironment are vital for the establishment and progression of bone metastases. Recently in Cancer Cell, Wang et al. (2018) showed that cells of the osteoblast lineage are critical for the delivery of calcium to tumor cells through gap junctions, pointing toward potential therapies for bone metastases.

Original language	English (US)
Pages (from-to)	6-8
Number of pages	3
Journal	Cell Metabolism
Volume	29
Issue number	1
DOIs	https://doi.org/10.1016/j.cmet.2018.12.014
State	Published - Jan 8 2019
Externally published	Yes

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

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10.1016/j.cmet.2018.12.014

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title = "A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone",

abstract = "Tumor cell interactions with the bone microenvironment are vital for the establishment and progression of bone metastases. Recently in Cancer Cell, Wang et al. (2018) showed that cells of the osteoblast lineage are critical for the delivery of calcium to tumor cells through gap junctions, pointing toward potential therapies for bone metastases.",

author = "Waning, {David L.} and Guise, {Theresa A.} and Mohammad, {Khalid S.}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2019",

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AU - Waning, David L.

AU - Guise, Theresa A.

AU - Mohammad, Khalid S.

PY - 2019/1/8

Y1 - 2019/1/8

N2 - Tumor cell interactions with the bone microenvironment are vital for the establishment and progression of bone metastases. Recently in Cancer Cell, Wang et al. (2018) showed that cells of the osteoblast lineage are critical for the delivery of calcium to tumor cells through gap junctions, pointing toward potential therapies for bone metastases.

AB - Tumor cell interactions with the bone microenvironment are vital for the establishment and progression of bone metastases. Recently in Cancer Cell, Wang et al. (2018) showed that cells of the osteoblast lineage are critical for the delivery of calcium to tumor cells through gap junctions, pointing toward potential therapies for bone metastases.

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DO - 10.1016/j.cmet.2018.12.014

M3 - Short survey

C2 - 30625309

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JO - Cell Metabolism

JF - Cell Metabolism

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A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone

Abstract

ASJC Scopus subject areas

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